PubMed

Nonmyeloablative HLA-Haploidentical BMT with High-Dose Posttransplantation Cyclophosphamide: Effect of HLA Disparity on Outcome.

Kasamon YL, Luznik L, Leffell MS, Kowalski J, Tsai HL, Bolaños-Meade J, Morris LE, Crilley PA, O'Donnell PV, Rossiter N, Huff CA, Brodsky RA, Matsui WH, Swinnen LJ, Borrello I, Powell JD, Ambinder RF, Jones RJ, Fuchs EJ.

Biol Blood Marrow Transplant. 2009 Nov 16. [Epub ahead of print]PMID: 19925877 [PubMed - as supplied by publisher]

Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma.

Kasamon YL, Jones RJ, Brodsky RA, Fuchs EJ, Matsui W, Luznik L, Powell JD, Blackford AL, Goodrich A, Gocke CD, Abrams RA, Ambinder RF, Flinn IW.

Ann Oncol. 2009 Oct 30. [Epub ahead of print]PMID: 19880437 [PubMed - as supplied by publisher]Related articles

Cyclophosphamide and cancer: golden anniversary.

Emadi A, Jones RJ, Brodsky RA.

Nat Rev Clin Oncol. 2009 Nov;6(11):638-47. Epub 2009 Sep 29.PMID: 19786984 [PubMed - in process]Related articles

Successful discontinuation of anticoagulation following eculizumab administration in paroxysmal nocturnal hemoglobinuria.

Emadi A, Brodsky RA.

Am J Hematol. 2009 Oct;84(10):699-701. No abstract available. PMID: 19705437 [PubMed - in process]Related articles

Blood and marrow transplantation for sickle cell disease: overcoming barriers to success.

Bolaños-Meade J, Brodsky RA.

Curr Opin Oncol. 2009 Mar;21(2):158-61. Review.PMID: 19532018 [PubMed - indexed for MEDLINE]Related articles

Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.

Singer AL, Locke JE, Stewart ZA, Lonze BE, Hamilton JP, Scudiere JR, Anders RA, Rother RP, Brodsky RA, Cameron AM.

Liver Transpl. 2009 May;15(5):540-3.PMID: 19399743 [PubMed - indexed for MEDLINE]Related articles

How I treat paroxysmal nocturnal hemoglobinuria.

Brodsky RA.

Blood. 2009 Jun 25;113(26):6522-7. Epub 2009 Apr 16.PMID: 19372253 [PubMed - indexed for MEDLINE]Related articles

Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.

Hu R, Mukhina GL, Lee SH, Jones RJ, Englund PT, Brown P, Sharkis SJ, Buckley JT, Brodsky RA.

Exp Hematol. 2009 Apr;37(4):423-434.e2.PMID: 19302917 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment versus transplant for challenging hematologic disorders.

Parker CJ, Brodsky RA, Levine JE.

Biol Blood Marrow Transplant. 2009 Jan;15(1 Suppl):72-8. No abstract available. PMID: 19147082 [PubMed - indexed for MEDLINE]Related articles

Successful pregnancy and childbirth after reduced-intensity conditioning and partially HLA-mismatched BMT.

Fuchs EJ, Luznik L, Bolaños-Meade J, Miller CB, Brodsky RA, Ambinder RF, Jones RJ.

Bone Marrow Transplant. 2009 Jun;43(12):969-70. Epub 2009 Jan 12. No abstract available. PMID: 19139737 [PubMed - indexed for MEDLINE]Related articles

Paroxysmal nocturnal hemoglobinuria: stem cells and clonality.

Brodsky RA.

Hematology Am Soc Hematol Educ Program. 2008:111-5.PMID: 19074067 [PubMed - indexed for MEDLINE]Related articlesFree article

High dose cyclophosphamide performs better than monthly dose cyclophosphamide in quality of life measures.

Dussán KB, Magder L, Brodsky RA, Jones RJ, Petri M.

Lupus. 2008 Dec;17(12):1079-85.PMID: 19029275 [PubMed - indexed for MEDLINE]Related articles

Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.

Savage WJ, Barber JP, Mukhina GL, Hu R, Chen G, Matsui W, Thoburn C, Hess AD, Cheng L, Jones RJ, Brodsky RA.

Exp Hematol. 2009 Jan;37(1):42-51. Epub 2008 Nov 14.PMID: 19013003 [PubMed - indexed for MEDLINE]Related articles

Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen.

Bolaños-Meade J, Luznik L, Muth M, Matsui WH, Huff CA, Smith BD, Levy MY, Kasamon YL, Swinnen LJ, Powell JD, Brodsky RA, Ambinder RF, Jones RJ, Fuchs EJ.

Bone Marrow Transplant. 2009 Mar;43(6):477-80. Epub 2008 Nov 3.PMID: 18978825 [PubMed - indexed for MEDLINE]Related articles

Intensive immunosuppression with high dose cyclophosphamide but without stem cell rescue for severe autoimmunity: Advantages and disadvantages.

Brodsky RA, Jones RJ.

Autoimmunity. 2008;41(8):596-600.PMID: 18958751 [PubMed - as supplied by publisher]Related articles

Reduced intensity HLA-haploidentical BMT with post transplantation cyclophosphamide in nonmalignant hematologic diseases.

Brodsky RA, Luznik L, Bolaños-Meade J, Leffell MS, Jones RJ, Fuchs EJ.

Bone Marrow Transplant. 2008 Oct;42(8):523-7. Epub 2008 Jul 14.PMID: 18622413 [PubMed - indexed for MEDLINE]Related articles

Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis.

Drachman DB, Adams RN, Hu R, Jones RJ, Brodsky RA.

Ann N Y Acad Sci. 2008;1132:305-14.PMID: 18567882 [PubMed - indexed for MEDLINE]Related articles

Reduction of disease activity and disability with high-dose cyclophosphamide in patients with aggressive multiple sclerosis.

Krishnan C, Kaplin AI, Brodsky RA, Drachman DB, Jones RJ, Pham DL, Richert ND, Pardo CA, Yousem DM, Hammond E, Quigg M, Trecker C, McArthur JC, Nath A, Greenberg BM, Calabresi PA, Kerr DA.

Arch Neurol. 2008 Aug;65(8):1044-51. Epub 2008 Jun 9.PMID: 18541787 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide.

Luznik L, O'Donnell PV, Symons HJ, Chen AR, Leffell MS, Zahurak M, Gooley TA, Piantadosi S, Kaup M, Ambinder RF, Huff CA, Matsui W, Bolaños-Meade J, Borrello I, Powell JD, Harrington E, Warnock S, Flowers M, Brodsky RA, Sandmaier BM, Storb RF, Jones RJ, Fuchs EJ.

Biol Blood Marrow Transplant. 2008 Jun;14(6):641-50.PMID: 18489989 [PubMed - indexed for MEDLINE]Related articlesFree article

Narrative review: paroxysmal nocturnal hemoglobinuria: the physiology of complement-related hemolytic anemia.

Brodsky RA.

Ann Intern Med. 2008 Apr 15;148(8):587-95. Review. No abstract available. PMID: 18413620 [PubMed - indexed for MEDLINE]Related articlesFree article

Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.

Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L.

Cell Stem Cell. 2008 Apr 10;2(4):345-55.PMID: 18397754 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria.

Brodsky RA.

Blood Rev. 2008 Mar;22(2):65-74. Epub 2007 Dec 3. Review.PMID: 18063459 [PubMed - indexed for MEDLINE]Related articlesFree article

Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.

Brodsky RA, Young NS, Antonioli E, Risitano AM, Schrezenmeier H, Schubert J, Gaya A, Coyle L, de Castro C, Fu CL, Maciejewski JP, Bessler M, Kroon HA, Rother RP, Hillmen P.

Blood. 2008 Feb 15;111(4):1840-7. Epub 2007 Nov 30.PMID: 18055865 [PubMed - indexed for MEDLINE]Related articlesFree article

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria.

Rother RP, Rollins SA, Mojcik CF, Brodsky RA, Bell L.

Nat Biotechnol. 2007 Nov;25(11):1256-64. Erratum in: Nat Biotechnol. 2007 Dec;25(12):1488. PMID: 17989688 [PubMed - indexed for MEDLINE]Related articles

High-dose cyclophosphamide without stem cell rescue in scleroderma.

Tehlirian CV, Hummers LK, White B, Brodsky RA, Wigley FM.

Ann Rheum Dis. 2008 Jun;67(6):775-81. Epub 2007 Nov 1.PMID: 17974598 [PubMed - indexed for MEDLINE]Related articles

New insights into paroxysmal nocturnal hemoglobinuria.

Savage WJ, Brodsky RA.

Hematology. 2007 Oct;12(5):371-6. Review.PMID: 17852463 [PubMed - indexed for MEDLINE]Related articles

Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.

Hillmen P, Muus P, Dührsen U, Risitano AM, Schubert J, Luzzatto L, Schrezenmeier H, Szer J, Brodsky RA, Hill A, Socié G, Bessler M, Rollins SA, Bell L, Rother RP, Young NS.

Blood. 2007 Dec 1;110(12):4123-8. Epub 2007 Aug 16.PMID: 17702897 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of hepatitis-associated aplastic anemia with high-dose cyclophosphamide.

Savage WJ, DeRusso PA, Resar LM, Chen AR, Higman MA, Loeb DM, Jones RJ, Brodsky RA.

Pediatr Blood Cancer. 2007 Dec;49(7):947-51.PMID: 17252566 [PubMed - indexed for MEDLINE]Related articles

New insights into paroxysmal nocturnal hemoglobinuria.

Brodsky RA.

Hematology Am Soc Hematol Educ Program. 2006:24-8, 516. Review.PMID: 17124035 [PubMed - indexed for MEDLINE]Related articlesFree article

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.

Hillmen P, Young NS, Schubert J, Brodsky RA, Socié G, Muus P, Röth A, Szer J, Elebute MO, Nakamura R, Browne P, Risitano AM, Hill A, Schrezenmeier H, Fu CL, Maciejewski J, Rollins SA, Mojcik CF, Rother RP, Luzzatto L.

N Engl J Med. 2006 Sep 21;355(12):1233-43.PMID: 16990386 [PubMed - indexed for MEDLINE]Related articlesFree article

PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.

Brodsky RA, Hu R.

Leuk Lymphoma. 2006 Jul;47(7):1215-21. Review.PMID: 16923549 [PubMed - indexed for MEDLINE]Related articles

A GPI-anchored co-receptor for tissue factor pathway inhibitor controls its intracellular trafficking and cell surface expression.

Maroney SA, Cunningham AC, Ferrel J, Hu R, Haberichter S, Mansbach CM, Brodsky RA, Dietzen DJ, Mast AE.

J Thromb Haemost. 2006 May;4(5):1114-24.PMID: 16689766 [PubMed - indexed for MEDLINE]Related articles

Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions.

Huff CA, Fuchs EJ, Smith BD, Blackford A, Garrett-Mayer E, Brodsky RA, Flinn IW, Ambinder RF, Borrello IM, Matsui WH, Vogelsang GB, Griffin CA, Luznik L, Jones RJ.

Biol Blood Marrow Transplant. 2006 Apr;12(4):414-21.PMID: 16545725 [PubMed - indexed for MEDLINE]Related articles

Catheter-directed thrombolysis and thrombectomy for the Budd-Chiari syndrome in paroxysmal nocturnal hemoglobinuria in three patients.

Kuo GP, Brodsky RA, Kim HS.

J Vasc Interv Radiol. 2006 Feb;17(2 Pt 1):383-7.PMID: 16517788 [PubMed - indexed for MEDLINE]Related articles

Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes.

Matsui WH, Brodsky RA, Smith BD, Borowitz MJ, Jones RJ.

Leukemia. 2006 Mar;20(3):458-62.PMID: 16437138 [PubMed - indexed for MEDLINE]Related articles

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita.

Armanios M, Chen JL, Chang YP, Brodsky RA, Hawkins A, Griffin CA, Eshleman JR, Cohen AR, Chakravarti A, Hamosh A, Greider CW.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15960-4. Epub 2005 Oct 24.PMID: 16247010 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe aplastic anemia associated with paroxysmal nocturnal hemoglobinuria and lymphoplasmacytic lymphoma.

Veidt RG, Ansari-Lari A, Brodsky RA.

Leuk Lymphoma. 2005 Aug;46(8):1243-6.PMID: 16085570 [PubMed - indexed for MEDLINE]Related articles

Aplastic anaemia.

Brodsky RA, Jones RJ.

Lancet. 2005 May 7-13;365(9471):1647-56. Review.PMID: 15885298 [PubMed - indexed for MEDLINE]Related articles

High-dose therapy for autoimmune neurologic diseases.

Drachman DB, Brodsky RA.

Curr Opin Oncol. 2005 Mar;17(2):83-8. Review.PMID: 15725909 [PubMed - indexed for MEDLINE]Related articles

PIG-A mutations in normal hematopoiesis.

Hu R, Mukhina GL, Piantadosi S, Barber JP, Jones RJ, Brodsky RA.

Blood. 2005 May 15;105(10):3848-54. Epub 2005 Feb 1.PMID: 15687243 [PubMed - indexed for MEDLINE]Related articlesFree article

Riddle: what do aplastic anemia, acute promyelocytic leukemia, and chronic myeloid leukemia have in common?

Brodsky RA, Jones RJ.

Leukemia. 2004 Oct;18(10):1740-2. Review.PMID: 15356647 [PubMed - indexed for MEDLINE]Related articles

Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.

Moyo VM, Mukhina GL, Garrett ES, Brodsky RA.

Br J Haematol. 2004 Jul;126(1):133-8.PMID: 15198744 [PubMed - indexed for MEDLINE]Related articles

Enhanced cytotoxicity of rituximab following genetic and biochemical disruption of glycosylphosphatidylinositol anchored proteins.

Nagajothi N, Matsui WH, Mukhina GL, Brodsky RA.

Leuk Lymphoma. 2004 Apr;45(4):795-9.PMID: 15160958 [PubMed - indexed for MEDLINE]Related articles

High-dose cyclophosphamide as salvage therapy for severe aplastic anemia.

Brodsky RA, Chen AR, Brodsky I, Jones RJ.

Exp Hematol. 2004 May;32(5):435-40.PMID: 15145211 [PubMed - indexed for MEDLINE]Related articles

High-dose cyclophosphamide in severe aplastic anaemia.

Jones RJ, Brodsky RA.

Br J Haematol. 2004 May;125(3):408-9; author reply 409-10. No abstract available. PMID: 15086426 [PubMed - indexed for MEDLINE]Related articles

High dose cyclophosphamide treatment for autoimmune disorders.

Brodsky RA.

ScientificWorldJournal. 2002 Jun 28;2:1808-15. Review.PMID: 12806171 [PubMed - indexed for MEDLINE]Related articles

Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: importance of allogeneic T cells.

Huff CA, Fuchs EJ, Noga SJ, O'Donnell PV, Ambinder RF, Diehl L, Borrello I, Vogelsang GB, Miller CB, Flinn IA, Brodsky RA, Marcellus D, Jones RJ.

Biol Blood Marrow Transplant. 2003 May;9(5):312-9.PMID: 12766881 [PubMed - indexed for MEDLINE]Related articles

Paroxysmal nocturnal hemoglobinuria arising from Fanconi anemia.

Wainwright L, Brodsky RA, Erasmus LK, Poyiadjis S, Naidu G, MacKinnon D.

J Pediatr Hematol Oncol. 2003 Feb;25(2):167-8.PMID: 12571472 [PubMed - indexed for MEDLINE]Related articles

High-dose cyclophosphamide without stem cell transplantation in systemic lupus erythematosus.

Petri M, Jones RJ, Brodsky RA.

Arthritis Rheum. 2003 Jan;48(1):166-73.PMID: 12528116 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of refractory myasthenia: "rebooting" with high-dose cyclophosphamide.

Drachman DB, Jones RJ, Brodsky RA.

Ann Neurol. 2003 Jan;53(1):29-34.PMID: 12509845 [PubMed - indexed for MEDLINE]Related articles