PubMed

A dietary combination of omega-3 and omega-6 polyunsaturated fatty acids is more efficient than single supplementations in the prevention of retinal damage induced by elevation of intraocular pressure in rats.

Schnebelen C, Pasquis B, Salinas-Navarro M, Joffre C, Creuzot-Garcher CP, Vidal-Sanz M, Bron AM, Bretillon L, Acar N.

Graefes Arch Clin Exp Ophthalmol. 2009 Nov 13. [Epub ahead of print] No abstract available. PMID: 19911188 [PubMed - as supplied by publisher]Related articles

Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma.

Acar N, Berdeaux O, Juaneda P, Grégoire S, Cabaret S, Joffre C, Creuzot-Garcher CP, Bretillon L, Bron AM.

Exp Eye Res. 2009 Dec;89(6):840-53. Epub 2009 Jul 21.PMID: 19627986 [PubMed - in process]Related articles

Primary Open Angle Glaucoma: Association with Cholesterol 24S-Hydroxylase (CYP46A1) Gene Polymorphism and Plasma 24-Hydroxycholesterol Levels.

Fourgeux C, Martine L, Björkhem I, Diczfalusy U, Joffre C, Acar N, Creuzot-Garcher C, Bron A, Bretillon L.

Invest Ophthalmol Vis Sci. 2009 Jun 24. [Epub ahead of print]PMID: 19553612 [PubMed - as supplied by publisher]Related articles

Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells.

Joffre C, Souchier M, Leclere L, Buteau B, Grégoire S, Lizard G, Montange T, Acar N, Bron A, Creuzot-Garcher C, Diebold Y, Bretillon L.

Br J Ophthalmol. 2009 Oct;93(10):1391-5. Epub 2009 Jun 10.PMID: 19520694 [PubMed - indexed for MEDLINE]Related articles

Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation.

Schnebelen C, Viau S, Grégoire S, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon L, Acar N.

Ophthalmic Res. 2009;41(4):216-24. Epub 2009 May 15.PMID: 19451735 [PubMed - indexed for MEDLINE]Related articles

A dietary combination of omega-3 and omega-6 polyunsaturated fatty acids is more efficient than single supplementations in the prevention of retinal damage induced by elevation of intraocular pressure in rats.

Schnebelen C, Pasquis B, Salinas-Navarro M, Joffre C, Creuzot-Garcher CP, Vidal-Sanz M, Bron AM, Bretillon L, Acar N.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1191-203. Epub 2009 May 13.PMID: 19437028 [PubMed - indexed for MEDLINE]Related articles

Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model.

Viau S, Maire MA, Pasquis B, Grégoire S, Acar N, Bron AM, Bretillon L, Creuzot-Garcher CP, Joffre C.

Graefes Arch Clin Exp Ophthalmol. 2009 Aug;247(8):1039-50. Epub 2009 May 5.PMID: 19415319 [PubMed - indexed for MEDLINE]Related articles

Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland.

Wu K, Joffre C, Li X, MacVeigh-Aloni M, Hom M, Hwang J, Ding C, Gregoire S, Bretillon L, Zhong JF, Hamm-Alvarez SF.

Exp Eye Res. 2009 Sep;89(3):319-32. Epub 2009 Apr 2.PMID: 19345210 [PubMed - indexed for MEDLINE]Related articles

Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels.

Schnebelen C, Grégoire S, Pasquis B, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon L, Acar N.

Lipids. 2009 May;44(5):465-70. Epub 2009 Feb 26.PMID: 19242743 [PubMed - indexed for MEDLINE]Related articles

Lipid and fatty acid profile of the retina, retinal pigment epithelium/choroid, and the lacrimal gland, and associations with adipose tissue fatty acids in human subjects.

Bretillon L, Thuret G, Grégoire S, Acar N, Joffre C, Bron AM, Gain P, Creuzot-Garcher CP.

Exp Eye Res. 2008 Dec;87(6):521-8. Epub 2008 Aug 29.PMID: 18801361 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of myocardial postconditioning are associated with reduced oxidative stress in a senescent mouse model.

Lauzier B, Delemasure S, Debin R, Collin B, Sicard P, Acar N, Bretillon L, Joffre C, Bron A, Creuzot-Garcher C, Vergely C, Rochette L.

Transplantation. 2008 Jun 27;85(12):1802-8.PMID: 18580474 [PubMed - indexed for MEDLINE]Related articles

Changes in meibomian fatty acids and clinical signs in patients with meibomian gland dysfunction after minocycline treatment.

Souchier M, Joffre C, Grégoire S, Bretillon L, Muselier A, Acar N, Beynat J, Bron A, D'Athis P, Creuzot-Garcher C.

Br J Ophthalmol. 2008 Jun;92(6):819-22. Epub 2008 May 29.PMID: 18511542 [PubMed - indexed for MEDLINE]Related articles

ApoB100,LDLR-/- mice exhibit reduced electroretinographic response and cholesteryl esters deposits in the retina.

Bretillon L, Acar N, Seeliger MW, Santos M, Maire MA, Juanéda P, Martine L, Grégoire S, Joffre C, Bron AM, Creuzot-Garcher C.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1307-14.PMID: 18385042 [PubMed - indexed for MEDLINE]Related articlesFree article

Time course of ocular surface and lacrimal gland changes in a new scopolamine-induced dry eye model.

Viau S, Maire MA, Pasquis B, Grégoire S, Fourgeux C, Acar N, Bretillon L, Creuzot-Garcher CP, Joffre C.

Graefes Arch Clin Exp Ophthalmol. 2008 Jun;246(6):857-67. Epub 2008 Mar 21.PMID: 18357464 [PubMed - indexed for MEDLINE]Related articles

Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye.

Joffre C, Souchier M, Grégoire S, Viau S, Bretillon L, Acar N, Bron AM, Creuzot-Garcher C.

Br J Ophthalmol. 2008 Jan;92(1):116-9.PMID: 18156378 [PubMed - indexed for MEDLINE]Related articles

Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats.

Sicard P, Acar N, Grégoire S, Lauzier B, Bron AM, Creuzot-Garcher C, Bretillon L, Vergely C, Rochette L.

Br J Pharmacol. 2007 Aug;151(7):979-86. Epub 2007 Jun 18.PMID: 17572703 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.

Bretillon L, Diczfalusy U, Björkhem I, Maire MA, Martine L, Joffre C, Acar N, Bron A, Creuzot-Garcher C.

Curr Eye Res. 2007 Apr;32(4):361-6.PMID: 17453958 [PubMed - indexed for MEDLINE]Related articles

Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.

Joffre C, Leclère L, Buteau B, Martine L, Cabaret S, Malvitte L, Acar N, Lizard G, Bron A, Creuzot-Garcher C, Bretillon L.

Curr Eye Res. 2007 Mar;32(3):271-80.PMID: 17453947 [PubMed - indexed for MEDLINE]Related articles

The retina is more susceptible than the brain and the liver to the incorporation of trans isomers of DHA in rats consuming trans isomers of alpha-linolenic acid.

Acar N, Bonhomme B, Joffre C, Bron AM, Creuzot-Garcher C, Bretillon L, Doly M, Chardigny JM.

Reprod Nutr Dev. 2006 Sep-Oct;46(5):515-25. Epub 2006 Sep 23.PMID: 17107641 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasmalogens in the retina: in situ hybridization of dihydroxyacetone phosphate acyltransferase (DHAP-AT)--the first enzyme involved in their biosynthesis--and comparative study of retinal and retinal pigment epithelial lipid composition.

Acar N, Gregoire S, Andre A, Juaneda P, Joffre C, Bron AM, Creuzot-Garcher CP, Bretillon L.

Exp Eye Res. 2007 Jan;84(1):143-51. Epub 2006 Nov 1.PMID: 17081518 [PubMed - indexed for MEDLINE]Related articles

In vivo oxidation of [9-14C] cyclic fatty acids derived from linolenic acid in the rat.

Bretillon L, Loreau O, Sébédio JL, Taran F.

Reprod Nutr Dev. 2006 Mar-Apr;46(2):189-93. Epub 2006 Apr 6.PMID: 16597424 [PubMed - indexed for MEDLINE]Related articlesFree article

In situ hybridization of dihydroxyacetone phosphate acyltransferase, the regulating enzyme involved in plasmalogen biosynthesis.

André A, Tessier C, Brétillon L, Sébédio JL, Chardigny JM.

Brain Res Mol Brain Res. 2005 May 20;136(1-2):142-7.PMID: 15893598 [PubMed - indexed for MEDLINE]Related articles

Metabolites of conjugated isomers of alpha-linolenic acid (CLnA) in the rat.

Destaillats F, Berdeaux O, Sébédio JL, Juaneda P, Grégoire S, Chardigny JM, Bretillon L, Angers P.

J Agric Food Chem. 2005 Mar 9;53(5):1422-7.PMID: 15740017 [PubMed - indexed for MEDLINE]Related articles

Fatty acid isomers in lipid metabolism.

Sébédio JL, Bretillon L, Chardigny JM, Berdeaux O.

Nestle Nutr Workshop Ser Clin Perform Programme. 2004;9:125-36; discussion 136-9. Review. No abstract available. PMID: 15361683 [PubMed - indexed for MEDLINE]Related articles

In vivo oxidation of carboxyl-labelled cyclic fatty acids formed from linoleic and linolenic acids in the rat.

Joffre F, Roy A, Bretillon L, Pasquis B, Sergiel JP, Loreau O, Chardigny JM, Sébédio JL.

Reprod Nutr Dev. 2004 Mar-Apr;44(2):123-30.PMID: 15270550 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor alpha is not the exclusive mediator of the effects of dietary cyclic FA in mice.

Bretillon L, Alexson SE, Joffre F, Pasquis B, Sébédio JL.

Lipids. 2003 Sep;38(9):957-63.PMID: 14584603 [PubMed - indexed for MEDLINE]Related articles

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease.

Heverin M, Bogdanovic N, Lütjohann D, Bayer T, Pikuleva I, Bretillon L, Diczfalusy U, Winblad B, Björkhem I.

J Lipid Res. 2004 Jan;45(1):186-93. Epub 2003 Oct 1.PMID: 14523054 [PubMed - indexed for MEDLINE]Related articlesFree article

Might analysis, synthesis and metabolism of CLA contribute to explain the biological effects of CLA?

Bretillon L, Sébédio JL, Chardigny JM.

Eur J Med Res. 2003 Aug 20;8(8):363-9. Review.PMID: 12915331 [PubMed - indexed for MEDLINE]Related articles

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells.

Bogdanovic N, Bretillon L, Lund EG, Diczfalusy U, Lannfelt L, Winblad B, Russell DW, Björkhem I.

Neurosci Lett. 2001 Nov 13;314(1-2):45-8.PMID: 11698143 [PubMed - indexed for MEDLINE]Related articles

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.

Bodin K, Bretillon L, Aden Y, Bertilsson L, Broomé U, Einarsson C, Diczfalusy U.

J Biol Chem. 2001 Oct 19;276(42):38685-9. Epub 2001 Aug 20.PMID: 11514559 [PubMed - indexed for MEDLINE]Related articlesFree article

Isomerization increases the postprandial oxidation of linoleic acid but not alpha-linolenic acid in men.

Bretillon L, Chardigny JM, Sébédio JL, Noël JP, Scrimgeour CM, Fernie CE, Loreau O, Gachon P, Beaufrère B.

J Lipid Res. 2001 Jun;42(6):995-7.PMID: 11369808 [PubMed - indexed for MEDLINE]Related articlesFree article

No effect of dietary trans isomers of alpha-linolenic acid on platelet aggregation and haemostatic factors in european healthy men. The TRANSLinE study.

Armstrong RA, Chardigny JM, Beaufrère B, Bretillon L, Vermunt SH, Mensink RP, Macvean A, Elton RA, Sébédio JL, Riemersma RA.

Thromb Res. 2000 Nov 1;100(3):133-41.PMID: 11108899 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.

Bretillon L, Sidén A, Wahlund LO, Lütjohann D, Minthon L, Crisby M, Hillert J, Groth CG, Diczfalusy U, Björkhem I.

Neurosci Lett. 2000 Oct 27;293(2):87-90.PMID: 11027840 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface.

Bretillon L, Lütjohann D, Ståhle L, Widhe T, Bindl L, Eggertsen G, Diczfalusy U, Björkhem I.

J Lipid Res. 2000 May;41(5):840-5.PMID: 10787445 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of conjugated linoleic acid isomers on the hepatic microsomal desaturation activities in vitro.

Bretillon L, Chardigny JM, Grégoire S, Berdeaux O, Sébédio JL.

Lipids. 1999 Sep;34(9):965-9.PMID: 10574661 [PubMed - indexed for MEDLINE]Related articles

Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and alpha-linolenic acids in perfused rat liver.

Bretillon L, Chardigny JM, Noël JP, Sébédio JL.

J Lipid Res. 1998 Nov;39(11):2228-36.PMID: 9799809 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro desaturation or elongation of monotrans isomers of linoleic acid by rat liver microsomes.

Berdeaux O, Blond JP, Bretillon L, Chardigny JM, Mairot T, Vatèle JM, Poullain D, Sébédio JL.

Mol Cell Biochem. 1998 Aug;185(1-2):17-25.PMID: 9746207 [PubMed - indexed for MEDLINE]Related articles

Oxidative metabolism of [1-14C] mono-trans isomers of linoleic and alpha-linolenic acids in the rat.

Bretillon L, Chardigny JM, Sébédio JL, Poullain D, Noël JP, Vatèle JM.

Biochim Biophys Acta. 1998 Feb 16;1390(2):207-14.PMID: 9507133 [PubMed - indexed for MEDLINE]Related articles

Conversion of 18:3 delta 9cis, 12cis, 15trans in rat liver microsomes.

Chardigny JM, Blond JP, Bretillon L, Mager E, Poullain D, Martine L, Vatèle JM, Noĕl JP, Sébédio JL.

Lipids. 1997 Jul;32(7):731-5.PMID: 9252961 [PubMed - indexed for MEDLINE]Related articles