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PHARMACOLOGIC ANTAGONISM OF THE ORAL AVERSIVE TASTE-DIRECTED RESPONSE TO CAPSAICIN IN A MOUSE BRIEF ACCESS TASTE AVERSION (BATA) ASSAY.

Long DL, Devantier HR, Brennan FX, Bryant RW, Salemme FR, Palmer RK.

J Pharmacol Exp Ther. 2009 Nov 10. [Epub ahead of print]PMID: 19903834 [PubMed - as supplied by publisher]Related articlesFree article

The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies.

Muller PY, Milton M, Lloyd P, Sims J, Brennan FR.

Curr Opin Biotechnol. 2009 Dec;20(6):722-9. Epub 2009 Nov 5.PMID: 19896825 [PubMed - in process]Related articles

Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis.

Hillyer P, Larché MJ, Bowman EP, McClanahan TK, de Waal Malefyt R, Schewitz LP, Giddins G, Feldmann M, Kastelein RA, Brennan FM.

Rheumatology (Oxford). 2009 Dec;48(12):1581-9. Epub 2009 Oct 8.PMID: 19815670 [PubMed - in process]Related articlesFree article

Advancing palliative care as a human right.

Gwyther L, Brennan F, Harding R.

J Pain Symptom Manage. 2009 Nov;38(5):767-74. Epub 2009 Sep 24.PMID: 19783399 [PubMed - in process]Related articles

TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.

Kuai J, Gregory B, Hill A, Pittman DD, Feldman JL, Brown T, Carito B, O'Toole M, Ramsey R, Adolfsson O, Shields KM, Dower K, Hall JP, Kurdi Y, Beech JT, Nanchahal J, Feldmann M, Foxwell BM, Brennan FM, Winkler DG, Lin LL.

Rheumatology (Oxford). 2009 Nov;48(11):1352-8. Epub 2009 Aug 27.PMID: 19713442 [PubMed - indexed for MEDLINE]Related articles

Invasive potential of human rheumatoid tenosynovial cells is in part MT1-MMP dependent.

Jain A, Miller MC, Troeberg L, Itoh Y, Brennan F, Nanchahal J.

J Hand Surg Am. 2009 Sep;34(7):1282-90. Epub 2009 Jul 12.PMID: 19596176 [PubMed - in process]Related articles

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

Midwood K, Sacre S, Piccinini AM, Inglis J, Trebaul A, Chan E, Drexler S, Sofat N, Kashiwagi M, Orend G, Brennan F, Foxwell B.

Nat Med. 2009 Jul;15(7):774-80. Epub 2009 Jun 28.PMID: 19561617 [PubMed - indexed for MEDLINE]Related articles

In memoriam: Professor Brian Maurice John Foxwell, 1956 to 2008.

Brennan F, Feldmann M.

Arthritis Res Ther. 2009;11(1):104. Epub 2009 Feb 27. No abstract available. PMID: 19473552 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiotherapy and cardiac rhythm devices: a review of the current scope of practice.

Digby GC, Daubney ME, Baggs J, Campbell D, Simpson CS, Redfearn DP, Brennan FJ, Abdollah H, Baranchuk A.

Europace. 2009 Jul;11(7):850-9. Epub 2009 May 2. Review.PMID: 19411677 [PubMed - indexed for MEDLINE]Related articles

Abdominal pain in a college football player.

Brennan FH Jr.

Curr Sports Med Rep. 2009 Mar-Apr;8(2):76. No abstract available. PMID: 19276907 [PubMed - indexed for MEDLINE]Related articles

Safety assessment and dose selection for first-in-human clinical trials with immunomodulatory monoclonal antibodies.

Muller PY, Brennan FR.

Clin Pharmacol Ther. 2009 Mar;85(3):247-58. Epub 2009 Jan 28. Review.PMID: 19177065 [PubMed - indexed for MEDLINE]Related articles

Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.

Sacre SM, Lo A, Gregory B, Simmonds RE, Williams L, Feldmann M, Brennan FM, Foxwell BM.

J Immunol. 2008 Dec 1;181(11):8002-9.PMID: 19017992 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of tumour necrosis factor production from mononuclear cells by a novel synthetic compound, CLX-090717.

Sumariwalla PF, Palmer CD, Pickford LB, Feldmann M, Foxwell BM, Brennan FM.

Rheumatology (Oxford). 2009 Jan;48(1):32-8. Epub 2008 Nov 16.PMID: 19015145 [PubMed - indexed for MEDLINE]Related articles

Return to physical activity after exertional rhabdomyolysis.

O'Connor FG, Brennan FH Jr, Campbell W, Heled Y, Deuster P.

Curr Sports Med Rep. 2008 Nov-Dec;7(6):328-31. Review.PMID: 19005354 [PubMed - indexed for MEDLINE]Related articles

Evidence that cytokines play a role in rheumatoid arthritis.

Brennan FM, McInnes IB.

J Clin Invest. 2008 Nov;118(11):3537-45. Review.PMID: 18982160 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative assessment of TRPM5-dependent oral aversiveness of pharmaceuticals using a mouse brief-access taste aversion assay.

Devantier HR, Long DJ, Brennan FX, Carlucci SA, Hendrix C, Bryant RW, Salemme FR, Palmer RK.

Behav Pharmacol. 2008 Oct;19(7):673-82.PMID: 18797244 [PubMed - indexed for MEDLINE]Related articles

"Those who knew the ways of water"--Bruce Dawe and the nature of palliative care.

Brennan F.

J Palliat Care. 2008 Summer;24(2):119-21. No abstract available. PMID: 18681249 [PubMed - indexed for MEDLINE]Related articles

Stress-induced increases in avoidance responding: an animal model of post-traumatic stress disorder behavior?

Brennan FX, Beck KD, Ross RJ, Servatius RJ.

Neuropsychiatr Dis Treat. 2005 Mar;1(1):69-72.PMID: 18568126 [PubMed - in process]Related articlesFree article

Neutralizing IL-21 and IL-15 inhibits pro-inflammatory cytokine production in rheumatoid arthritis.

Andersson AK, Feldmann M, Brennan FM.

Scand J Immunol. 2008 Jul;68(1):103-11. Epub 2008 May 9.PMID: 18482208 [PubMed - indexed for MEDLINE]Related articles

Long-term effect of cued fear conditioning on REM sleep microarchitecture in rats.

Madan V, Brennan FX, Mann GL, Horbal AA, Dunn GA, Ross RJ, Morrison AR.

Sleep. 2008 Apr 1;31(4):497-503.PMID: 18457237 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-10 regulates TNF-alpha-converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism.

Brennan FM, Green P, Amjadi P, Robertshaw HJ, Alvarez-Iglesias M, Takata M.

Eur J Immunol. 2008 Apr;38(4):1106-17.PMID: 18383040 [PubMed - indexed for MEDLINE]Related articles

Recent developments in the immunobiology of rheumatoid arthritis.

Andersson AK, Li C, Brennan FM.

Arthritis Res Ther. 2008;10(2):204. Epub 2008 Mar 14. Review.PMID: 18373887 [PubMed - indexed for MEDLINE]Related articlesFree article

Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function.

Brennan FM, Smith NM, Owen S, Li C, Amjadi P, Green P, Andersson A, Palfreeman AC, Hillyer P, Foey A, Beech JT, Feldmann M.

Arthritis Res Ther. 2008;10(2):R36. Epub 2008 Mar 19.PMID: 18353171 [PubMed - indexed for MEDLINE]Related articlesFree article

Rac mediates TNF-induced cytokine production via modulation of NF-kappaB.

Williams LM, Lali F, Willetts K, Balague C, Godessart N, Brennan F, Feldmann M, Foxwell BM.

Mol Immunol. 2008 May;45(9):2446-54. Epub 2008 Feb 6. Review.PMID: 18258304 [PubMed - indexed for MEDLINE]Related articles

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

Elliot MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Katasikis P, Brennan FM, Bijl H, Ghrayeb J, Woody JN.

Arthritis Rheum. 2008 Feb;58(2 Suppl):S92-S101.PMID: 18240199 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of opioids in pain management.

Brennan F, Carr DB, Cousins M.

Anesth Analg. 2007 Dec;105(6):1865-6; author reply 1866. No abstract available. PMID: 18042900 [PubMed - indexed for MEDLINE]Related articles

Could toll-like receptors provide a missing link in chronic inflammation in rheumatoid arthritis? Lessons from a study on human rheumatoid tissue.

Sacre SM, Drexler SK, Andreakos E, Feldmann M, Brennan FM, Foxwell BM.

Ann Rheum Dis. 2007 Nov;66 Suppl 3:iii81-6. Review.PMID: 17934103 [PubMed - indexed for MEDLINE]Related articles

Preparation of mononuclear cells from synovial tissue.

Beech JT, Brennan FM.

Methods Mol Med. 2007;135:105-19.PMID: 17951655 [PubMed - indexed for MEDLINE]Related articles

Stress-induced changes in sleep in rodents: models and mechanisms.

Pawlyk AC, Morrison AR, Ross RJ, Brennan FX.

Neurosci Biobehav Rev. 2008;32(1):99-117. Epub 2007 Jun 29. Review.PMID: 17764741 [PubMed - indexed for MEDLINE]Related articlesFree article

Pain management: a fundamental human right.

Brennan F, Carr DB, Cousins M.

Anesth Analg. 2007 Jul;105(1):205-21. Review.PMID: 17578977 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis.

Edwards CJ, Feldman JL, Beech J, Shields KM, Stover JA, Trepicchio WL, Larsen G, Foxwell BM, Brennan FM, Feldmann M, Pittman DD.

Mol Med. 2007 Jan-Feb;13(1-2):40-58.PMID: 17515956 [PubMed - indexed for MEDLINE]Related articlesFree article

Palliative care as an international human right.

Brennan F.

J Pain Symptom Manage. 2007 May;33(5):494-9. Review.PMID: 17482036 [PubMed - indexed for MEDLINE]Related articles

The athletic preparticipation evaluation: cardiovascular assessment.

Giese EA, O'Connor FG, Brennan FH, Depenbrock PJ, Oriscello RG.

Am Fam Physician. 2007 Apr 1;75(7):1008-14. Review.PMID: 17427614 [PubMed - indexed for MEDLINE]Related articles

Update on cytokines in rheumatoid arthritis.

Brennan F, Beech J.

Curr Opin Rheumatol. 2007 May;19(3):296-301. Review.PMID: 17414959 [PubMed - indexed for MEDLINE]Related articles

Words.

Brennan F.

Ann Intern Med. 2007 Mar 20;146(6):464. No abstract available. PMID: 17371893 [PubMed - indexed for MEDLINE]Related articlesFree article

TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

Zhang Z, Gorman CL, Vermi AC, Monaco C, Foey A, Owen S, Amjadi P, Vallance A, McClinton C, Marelli-Berg F, Isomäki P, Russell A, Dazzi F, Vyse TJ, Brennan FM, Cope AP.

Blood. 2007 May 15;109(10):4328-35. Epub 2007 Jan 25.PMID: 17255353 [PubMed - indexed for MEDLINE]Related articlesFree article

The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.

Sacre SM, Andreakos E, Kiriakidis S, Amjadi P, Lundberg A, Giddins G, Feldmann M, Brennan F, Foxwell BM.

Am J Pathol. 2007 Feb;170(2):518-25.PMID: 17255320 [PubMed - indexed for MEDLINE]Related articlesFree article

A direct effect of aldosterone on endothelin-1 gene expression in vivo.

Wong S, Brennan FE, Young MJ, Fuller PJ, Cole TJ.

Endocrinology. 2007 Apr;148(4):1511-7. Epub 2007 Jan 11.PMID: 17218419 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of constitutively active STAT3 can replicate the cytokine-suppressive activity of interleukin-10 in human primary macrophages.

Williams LM, Sarma U, Willets K, Smallie T, Brennan F, Foxwell BM.

J Biol Chem. 2007 Mar 9;282(10):6965-75. Epub 2006 Dec 27.PMID: 17194701 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFkappaB: implications for rheumatoid arthritis.

Beech JT, Andreakos E, Ciesielski CJ, Green P, Foxwell BM, Brennan FM.

Arthritis Res Ther. 2006;8(6):R168.PMID: 17101049 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy of particle-based DNA delivery for vaccination of sheep against FMDV.

Niborski V, Li Y, Brennan F, Lane M, Torché AM, Remond M, Bonneau M, Riffault S, Stirling C, Hutchings G, Takamatsu H, Barnett P, Charley B, Schwartz-Cornil I.

Vaccine. 2006 Nov 30;24(49-50):7204-13. Epub 2006 Jul 7.PMID: 16949709 [PubMed - indexed for MEDLINE]Related articles

Fmr1 knockout mice are impaired in a leverpress escape/avoidance task.

Brennan FX, Albeck DS, Paylor R.

Genes Brain Behav. 2006 Aug;5(6):467-71.PMID: 16923151 [PubMed - indexed for MEDLINE]Related articles

Centrally administered tumor necrosis factor-alpha facilitates the avoidance performance of Sprague-Dawley rats.

Brennan FX, Tieder JB 3rd.

Brain Res. 2006 Sep 13;1109(1):142-5. Epub 2006 Jul 11.PMID: 16836982 [PubMed - indexed for MEDLINE]Related articles

The importance of T cell interactions with macrophages in rheumatoid cytokine production.

Brennan FM, Foey AD, Feldmann M.

Curr Top Microbiol Immunol. 2006;305:177-94. Review.PMID: 16724806 [PubMed - indexed for MEDLINE]Related articles

Silent.

Brennan F.

Am J Hosp Palliat Care. 2006 Mar-Apr;23(2):157-8. No abstract available. PMID: 16572755 [PubMed - indexed for MEDLINE]Related articles

Mammalian K-ras2 is a corticosteroid-induced gene in vivo.

Brennan FE, Fuller PJ.

Endocrinology. 2006 Jun;147(6):2809-16. Epub 2006 Mar 16.PMID: 16543373 [PubMed - indexed for MEDLINE]Related articlesFree article

Corticotropin-releasing factor microinjection into the central nucleus of the amygdala alters REM sleep.

Pawlyk AC, Sanford LD, Brennan FX, Morrison AR, Ross RJ.

Pharmacol Rep. 2006 Jan-Feb;58(1):125-30.PMID: 16531640 [PubMed - indexed for MEDLINE]Related articlesFree article

Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production.

Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, Brennan FM, Webster D, Foxwell BM.

J Immunol. 2006 Mar 15;176(6):3635-41.PMID: 16517732 [PubMed - indexed for MEDLINE]Related articlesFree article

Predator odor exposure facilitates acquisition of a leverpress avoidance response in rats.

Brennan FX, Beck KD, Servatius RJ.

Neuropsychiatr Dis Treat. 2006 Mar;2(1):65-9.PMID: 19412447 [PubMed - in process]Related articlesFree article

Leverpress escape/avoidance training increases neurotrophin levels in rat brain.

Albeck DS, Beck KD, Kung LH, Sano K, Brennan FX.

Integr Physiol Behav Sci. 2005 Jan-Mar;40(1):28-34.PMID: 16491929 [PubMed - indexed for MEDLINE]Related articles