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    Results: 28

    1.

    Selective inhibition of retinal angiogenesis by targeting PI3 kinase.

    Alvarez Y, Astudillo O, Jensen L, Reynolds AL, Waghorne N, Brazil DP, Cao Y, O'Connor JJ, Kennedy BN.

    PLoS One. 2009 Nov 17;4(11):e7867.PMID: 19924235 [PubMed - in process]Related articlesFree article

    2.

    High-Frequency Ultrasound Assessment of the Murine Heart From Embryo Through to Juvenile.

    Corrigan N, Brazil DP, McAuliffe FM.

    Reprod Sci. 2009 Oct 20. [Epub ahead of print]PMID: 19843878 [PubMed - as supplied by publisher]Related articles

    3.

    Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

    Piao L, Li Y, Yang KJ, Park KA, Byun HS, Won M, Hong J, Kim JL, Kweon GR, Hur GM, Seok JH, Cho JY, Chun T, Hess D, Sack R, Maira SM, Brazil DP, Hemmings BA, Park J.

    BMC Cell Biol. 2009 Jul 15;10:53.PMID: 19604401 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Comparative analysis of DNA methylation profiles in peripheral blood leukocytes versus lymphoblastoid cell lines.

    Brennan EP, Ehrich M, Brazil DP, Crean JK, Murphy M, Sadlier DM, Martin F, Godson C, McKnight AJ, van den Boom D, Maxwell AP, Savage DA.

    Epigenetics. 2009 Apr;4(3):159-64. Epub 2009 Apr 18.PMID: 19440041 [PubMed - indexed for MEDLINE]Related articles

    5.

    The Carboxy-Terminal Modulator Protein (CTMP) regulates mitochondrial dynamics.

    Parcellier A, Tintignac LA, Zhuravleva E, Dummler B, Brazil DP, Hynx D, Cron P, Schenk S, Olivieri V, Hemmings BA.

    PLoS One. 2009;4(5):e5471. Epub 2009 May 7.PMID: 19421406 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Allelic depletion of grem1 attenuates diabetic kidney disease.

    Roxburgh SA, Kattla JJ, Curran SP, O'Meara YM, Pollock CA, Goldschmeding R, Godson C, Martin F, Brazil DP.

    Diabetes. 2009 Jul;58(7):1641-50. Epub 2009 Apr 28.PMID: 19401426 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death.

    Piao L, Li Y, Kim SJ, Byun HS, Huang SM, Hwang SK, Yang KJ, Park KA, Won M, Hong J, Hur GM, Seok JH, Shong M, Cho MH, Brazil DP, Hemmings BA, Park J.

    Cancer Res. 2009 Apr 15;69(8):3397-404. Epub 2009 Mar 24.PMID: 19318571 [PubMed - indexed for MEDLINE]Related articles

    8.

    Fetal cardiac effects of maternal hyperglycemia during pregnancy.

    Corrigan N, Brazil DP, McAuliffe F.

    Birth Defects Res A Clin Mol Teratol. 2009 Jun;85(6):523-30. Review.PMID: 19180650 [PubMed - indexed for MEDLINE]Related articles

    9.

    Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis.

    Piao L, Li Y, Kim SJ, Sohn KC, Yang KJ, Park KA, Byun HS, Won M, Hong J, Hur GM, Seok JH, Shong M, Sack R, Brazil DP, Hemmings BA, Park J.

    Cell Signal. 2009 May;21(5):767-77. Epub 2009 Jan 9.PMID: 19168126 [PubMed - indexed for MEDLINE]Related articles

    10.

    DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif.

    Park J, Feng J, Li Y, Hammarsten O, Brazil DP, Hemmings BA.

    J Biol Chem. 2009 Mar 6;284(10):6169-74. Epub 2009 Jan 14.PMID: 19144640 [PubMed - indexed for MEDLINE]Related articles

    11.

    Regulation and consequences of differential gene expression in diabetic kidney disease.

    Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, Godson C.

    Biochem Soc Trans. 2008 Oct;36(Pt 5):941-5.PMID: 18793165 [PubMed - indexed for MEDLINE]Related articles

    12.

    Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.

    Kattla JJ, Carew RM, Heljic M, Godson C, Brazil DP.

    Am J Physiol Renal Physiol. 2008 Jul;295(1):F215-25. Epub 2008 May 21.PMID: 18495798 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

    Yang KJ, Shin S, Piao L, Shin E, Li Y, Park KA, Byun HS, Won M, Hong J, Kweon GR, Hur GM, Seok JH, Chun T, Brazil DP, Hemmings BA, Park J.

    J Biol Chem. 2008 Jan 18;283(3):1480-91. Epub 2007 Nov 16.PMID: 18024423 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Co-regulation of Gremlin and Notch signalling in diabetic nephropathy.

    Walsh DW, Roxburgh SA, McGettigan P, Berthier CC, Higgins DG, Kretzler M, Cohen CD, Mezzano S, Brazil DP, Martin F.

    Biochim Biophys Acta. 2008 Jan;1782(1):10-21. Epub 2007 Oct 11.PMID: 17980714 [PubMed - indexed for MEDLINE]Related articles

    15.

    Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1alpha and promotes cell viability.

    Barry RE, Allan BB, Cummins EP, Kattla JJ, Giblin A, Scally N, Taylor CT, Brazil DP.

    Eur J Cell Biol. 2007 Jul;86(7):393-403. Epub 2007 Jun 4.PMID: 17544543 [PubMed - indexed for MEDLINE]Related articles

    16.

    Recapitulation of embryological programmes in renal fibrosis--the importance of epithelial cell plasticity and developmental genes.

    Roxburgh SA, Murphy M, Pollock CA, Brazil DP.

    Nephron Physiol. 2006;103(3):p139-48. Epub 2006 Mar 23. Review.PMID: 16582577 [PubMed - indexed for MEDLINE]Related articles

    17.

    Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.

    Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA.

    J Biol Chem. 2004 Aug 20;279(34):35510-7. Epub 2004 May 28.PMID: 15169778 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Advances in protein kinase B signalling: AKTion on multiple fronts.

    Brazil DP, Yang ZZ, Hemmings BA.

    Trends Biochem Sci. 2004 May;29(5):233-42. Review. No abstract available. PMID: 15130559 [PubMed - indexed for MEDLINE]Related articles

    19.

    Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy.

    Sadlier DM, Connolly SB, Kieran NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DC, Doran P, Brady HR.

    J Biol Chem. 2004 Jul 9;279(28):29670-80. Epub 2004 Mar 18.PMID: 15033991 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.

    Schubert M, Brazil DP, Burks DJ, Kushner JA, Ye J, Flint CL, Farhang-Fallah J, Dikkes P, Warot XM, Rio C, Corfas G, White MF.

    J Neurosci. 2003 Aug 6;23(18):7084-92.PMID: 12904469 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    PKB binding proteins. Getting in on the Akt.

    Brazil DP, Park J, Hemmings BA.

    Cell. 2002 Nov 1;111(3):293-303. Review.PMID: 12419241 [PubMed - indexed for MEDLINE]Related articles

    22.

    Ten years of protein kinase B signalling: a hard Akt to follow.

    Brazil DP, Hemmings BA.

    Trends Biochem Sci. 2001 Nov;26(11):657-64. Review.PMID: 11701324 [PubMed - indexed for MEDLINE]Related articles

    23.

    Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.

    Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA.

    Science. 2001 Oct 12;294(5541):374-80.PMID: 11598301 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.

    Park J, Hill MM, Hess D, Brazil DP, Hofsteenge J, Hemmings BA.

    J Biol Chem. 2001 Oct 5;276(40):37459-71. Epub 2001 Jul 31.PMID: 11481331 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase.

    Hill MM, Andjelkovic M, Brazil DP, Ferrari S, Fabbro D, Hemmings BA.

    J Biol Chem. 2001 Jul 13;276(28):25643-6. Epub 2001 May 23.PMID: 11373274 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase.

    Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK.

    Nature. 2000 Sep 28;407(6803):538-41.PMID: 11029009 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    Cell polarity: Scaffold proteins par excellence.

    Brazil DP, Hemmings BA.

    Curr Biol. 2000 Aug 24;10(16):R592-4.PMID: 10985375 [PubMed - indexed for MEDLINE]Related articles

    28.

    On the mechanism of the inhibition of transducin function by farnesylcysteine analogs.

    Parish CA, Brazil DP, Rando RR.

    Biochemistry. 1997 Mar 4;36(9):2686-93.PMID: 9054576 [PubMed - indexed for MEDLINE]Related articles

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