PubMed

Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition.

Battaglia S, Benzoubir N, Nobilet S, Charneau P, Samuel D, Zignego AL, Atfi A, Bréchot C, Bourgeade MF.

PLoS One. 2009;4(2):e4355. Epub 2009 Feb 3.PMID: 19190755 [PubMed - indexed for MEDLINE]Related articlesFree article

Internal radiotherapy of liver cancer with rat hepatocarcinoma-intestine-pancreas gene as a liver tumor-specific promoter.

Hervé J, Cunha AS, Liu B, Valogne Y, Longuet M, Boisgard R, Brégerie O, Roux J, Guettier C, Calès P, Tavitian B, Samuel D, Clerc J, Bréchot C, Faivre J.

Hum Gene Ther. 2008 Sep;19(9):915-26.PMID: 18759560 [PubMed - indexed for MEDLINE]Related articles

Internal radiotherapy of liver cancer with rat Hepatocarcinoma-Intestine-Pancreas gene as a liver tumor-specific promoter.

Herve J, Sa Cunha A, Liu B, Valogne Y, Longuet M, Boisgard R, Bregerie O, Roux J, Guettier C, Cales P, Tavitian B, Samuel D, Clerc J, Brechot C, Faivre J.

Hum Gene Ther. 2008 Jul 7. [Epub ahead of print]PMID: 18605895 [PubMed - as supplied by publisher]Related articles

Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells.

Yan XB, Mei L, Feng X, Wan MR, Chen Z, Pavio N, Brechot C.

World J Gastroenterol. 2008 May 14;14(18):2877-81.PMID: 18473414 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocellular carcinoma is associated with an increased risk of hepatitis B virus recurrence after liver transplantation.

Faria LC, Gigou M, Roque-Afonso AM, Sebagh M, Roche B, Fallot G, Ferrari TC, Guettier C, Dussaix E, Castaing D, Brechot C, Samuel D.

Gastroenterology. 2008 Jun;134(7):1890-9; quiz 2155. Epub 2008 Mar 4.PMID: 18424269 [PubMed - indexed for MEDLINE]Related articles

Change in hepatitis C virus genotype in hemodialysis patients after end-of-treatment response to interferon monotherapy--relapse or re-infection?

Arrais TC, Van Dooren S, Vandamme AM, Brechot C, Rimlinger F, Silva AE, Perez RM, Ferraz ML, Thiers V.

J Med Virol. 2008 Jan;80(1):80-6.PMID: 18041025 [PubMed - indexed for MEDLINE]Related articles

Biobanking for Europe.

Yuille M, van Ommen GJ, Bréchot C, Cambon-Thomsen A, Dagher G, Landegren U, Litton JE, Pasterk M, Peltonen L, Taussig M, Wichmann HE, Zatloukal K.

Brief Bioinform. 2008 Jan;9(1):14-24. Epub 2007 Oct 23. Review.PMID: 17959611 [PubMed - indexed for MEDLINE]Related articles

Distinct hepatitis C virus core and F protein quasispecies in tumoral and nontumoral hepatocytes isolated via microdissection.

Sobesky R, Feray C, Rimlinger F, Derian N, Dos Santos A, Roque-Afonso AM, Samuel D, Bréchot C, Thiers V.

Hepatology. 2007 Dec;46(6):1704-12.PMID: 17935229 [PubMed - indexed for MEDLINE]Related articles

Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.

Liu B, Hervé J, Bioulac-Sage P, Valogne Y, Roux J, Yilmaz F, Boisgard R, Guettier C, Calès P, Tavitian B, Samuel D, Clerc J, Bréchot C, Faivre J.

Gastroenterology. 2007 Apr;132(4):1495-503. Epub 2007 Jan 26.PMID: 17408651 [PubMed - indexed for MEDLINE]Related articles

[Impact of calcium signaling in liver carcinogenesis]

Chami M, Benali NL, Bréchot C, Paterlini-Bréchot P.

Med Sci (Paris). 2007 Feb;23(2):133-5. French. No abstract available. PMID: 17291421 [PubMed - indexed for MEDLINE]Related articles

Mapping of the interacting domains of hepatitis C virus core protein and the double-stranded RNA-activated protein kinase PKR.

Yan XB, Battaglia S, Boucreux D, Chen Z, Brechot C, Pavio N.

Virus Res. 2007 Apr;125(1):79-87. Epub 2007 Jan 30.PMID: 17267064 [PubMed - indexed for MEDLINE]Related articles

The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells.

Robert A, Margall-Ducos G, Guidotti JE, Brégerie O, Celati C, Bréchot C, Desdouets C.

J Cell Sci. 2007 Feb 15;120(Pt 4):628-37. Epub 2007 Jan 30. Erratum in: J Cell Sci. 2007 Mar 1;120(Pt 5):918. PMID: 17264151 [PubMed - indexed for MEDLINE]Related articlesFree article

Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice.

Lieu HT, Simon MT, Nguyen-Khoa T, Kebede M, Cortes A, Tebar L, Smith AJ, Bayne R, Hunt SP, Bréchot C, Christa L.

Hepatology. 2006 Dec;44(6):1452-64.PMID: 17133485 [PubMed - indexed for MEDLINE]Related articles

Conserved balance of hepatocyte nuclear DNA content in mononuclear and binuclear hepatocyte populations during the course of chronic viral hepatitis.

Toyoda H, Kumada T, Bregerie O, Brechot C, Desdouets C.

World J Gastroenterol. 2006 Jul 28;12(28):4546-8.PMID: 16874869 [PubMed - indexed for MEDLINE]Related articlesFree article

HIP/PAP, a member of the reg family, is expressed in glucagon-producing enteropancreatic endocrine cells and tumors.

Hervieu V, Christa L, Gouysse G, Bouvier R, Chayvialle JA, Bréchot C, Scoazec JY.

Hum Pathol. 2006 Aug;37(8):1066-75. Epub 2006 Jun 16.PMID: 16867870 [PubMed - indexed for MEDLINE]Related articles

Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis.

Kremsdorf D, Soussan P, Paterlini-Brechot P, Brechot C.

Oncogene. 2006 Jun 26;25(27):3823-33. Review.PMID: 16799624 [PubMed - indexed for MEDLINE]Related articles

Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera.

Chignard N, Shang S, Wang H, Marrero J, Bréchot C, Hanash S, Beretta L.

Gastroenterology. 2006 Jun;130(7):2010-22.PMID: 16762624 [PubMed - indexed for MEDLINE]Related articles

Liver-stage development of Plasmodium falciparum, in a humanized mouse model.

Morosan S, Hez-Deroubaix S, Lunel F, Renia L, Giannini C, Van Rooijen N, Battaglia S, Blanc C, Eling W, Sauerwein R, Hannoun L, Belghiti J, Brechot C, Kremsdorf D, Druilhe P.

J Infect Dis. 2006 Apr 1;193(7):996-1004. Epub 2006 Feb 28.PMID: 16518762 [PubMed - indexed for MEDLINE]Related articles

Automated grading of research performance clearly fails to measure up.

Haeffner-Cavaillon N, Graillot-Gak C, Bréchot C.

Nature. 2005 Dec 1;438(7068):559. No abstract available. PMID: 16319861 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunogenicity of a hepatitis B DNA vaccine administered to chronic HBV carriers.

Mancini-Bourgine M, Fontaine H, Bréchot C, Pol S, Michel ML.

Vaccine. 2006 May 22;24(21):4482-9. Epub 2005 Aug 18.PMID: 16310901 [PubMed - indexed for MEDLINE]Related articles

Human MxA protein participates to the interferon-related inhibition of hepatitis B virus replication in female transgenic mice.

Peltekian C, Gordien E, Garreau F, Meas-Yedid V, Soussan P, Willams V, Chaix ML, Olivo-Marin JC, Bréchot C, Kremsdorf D.

J Hepatol. 2005 Dec;43(6):965-72. Epub 2005 Jul 14.PMID: 16168514 [PubMed - indexed for MEDLINE]Related articles

HIP/PAP accelerates liver regeneration and protects against acetaminophen injury in mice.

Lieu HT, Batteux F, Simon MT, Cortes A, Nicco C, Zavala F, Pauloin A, Tralhao JG, Soubrane O, Weill B, Bréchot C, Christa L.

Hepatology. 2005 Sep;42(3):618-26.PMID: 16116631 [PubMed - indexed for MEDLINE]Related articles

Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas.

Murakami Y, Saigo K, Takashima H, Minami M, Okanoue T, Bréchot C, Paterlini-Bréchot P.

Gut. 2005 Aug;54(8):1162-8.PMID: 16009689 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatitis C virus core variants isolated from liver tumor but not from adjacent non-tumor tissue interact with Smad3 and inhibit the TGF-beta pathway.

Pavio N, Battaglia S, Boucreux D, Arnulf B, Sobesky R, Hermine O, Brechot C.

Oncogene. 2005 Sep 8;24(40):6119-32.PMID: 16007207 [PubMed - indexed for MEDLINE]Related articles

Hepatitis C virus particles and lipoprotein metabolism.

André P, Perlemuter G, Budkowska A, Bréchot C, Lotteau V.

Semin Liver Dis. 2005 Feb;25(1):93-104. Review.PMID: 15732001 [PubMed - indexed for MEDLINE]Related articles

Changes to hepatocyte ploidy and binuclearity profiles during human chronic viral hepatitis.

Toyoda H, Bregerie O, Vallet A, Nalpas B, Pivert G, Brechot C, Desdouets C.

Gut. 2005 Feb;54(2):297-302.PMID: 15647198 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats.

Faivre J, Clerc J, Gérolami R, Hervé J, Longuet M, Liu B, Roux J, Moal F, Perricaudet M, Bréchot C.

Cancer Res. 2004 Nov 1;64(21):8045-51. Erratum in: Cancer Res. 2004 Dec 15;64(24):9230. PMID: 15520214 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms.

Bréchot C.

Gastroenterology. 2004 Nov;127(5 Suppl 1):S56-61. Review.PMID: 15508104 [PubMed - indexed for MEDLINE]Related articles

[Health translational research, a new paradigm]

Bréchot C.

Med Sci (Paris). 2004 Oct;20(10):939-40. French. No abstract available. PMID: 15461977 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers.

Mancini-Bourgine M, Fontaine H, Scott-Algara D, Pol S, Bréchot C, Michel ML.

Hepatology. 2004 Oct;40(4):874-82.PMID: 15382173 [PubMed - indexed for MEDLINE]Related articles

HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RII alpha regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling.

Demaugre F, Philippe Y, Sar S, Pileire B, Christa L, Lasserre C, Brechot C.

Eur J Biochem. 2004 Oct;271(19):3812-20.PMID: 15373827 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses.

Girard S, Vossman E, Misek DE, Podevin P, Hanash S, Bréchot C, Beretta L.

Hepatology. 2004 Sep;40(3):708-18.PMID: 15349911 [PubMed - indexed for MEDLINE]Related articles

Intrahepatic hepatitis C virus RNA quantification in microdissected hepatocytes.

Vona G, Tuveri R, Delpuech O, Vallet A, Canioni D, Ballardini G, Baptiste Trabut J, Le Bail B, Nalpas B, Carnot F, Pol S, Brechot C, Thiers V.

J Hepatol. 2004 Apr;40(4):682-8.PMID: 15030986 [PubMed - indexed for MEDLINE]Related articles

Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer.

Vona G, Estepa L, Béroud C, Damotte D, Capron F, Nalpas B, Mineur A, Franco D, Lacour B, Pol S, Bréchot C, Paterlini-Bréchot P.

Hepatology. 2004 Mar;39(3):792-7.PMID: 14999698 [PubMed - indexed for MEDLINE]Related articles

Influence of HFE gene polymorphism on the progression and treatment of chronic hepatitis C.

Lebray P, Zylberberg H, Hue S, Poulet B, Carnot F, Martin S, Chretien Y, Pol S, Caillat-Zuckman S, Bréchot C, Nalpas B.

J Viral Hepat. 2004 Mar;11(2):175-82.PMID: 14996353 [PubMed - indexed for MEDLINE]Related articles

Reversibility of hepatitis C virus-related cirrhosis.

Pol S, Carnot F, Nalpas B, Lagneau JL, Fontaine H, Serpaggi J, Serfaty L, Bedossa P, Bréchot C.

Hum Pathol. 2004 Jan;35(1):107-12.PMID: 14745732 [PubMed - indexed for MEDLINE]Related articles

Herpes simplex virus thymidine kinase-mediated suicide gene therapy for hepatocellular carcinoma using HIV-1-derived lentiviral vectors.

Gerolami R, Uch R, Faivre J, Garcia S, Hardwigsen J, Cardoso J, Mathieu S, Bagnis C, Brechot C, Mannoni P.

J Hepatol. 2004 Feb;40(2):291-7.PMID: 14739101 [PubMed - indexed for MEDLINE]Related articles

Immunomodulatory drugs and therapeutic vaccine in chronic hepatitis B infection.

Lebray P, Vallet-Pichard A, Michel ML, Fontaine H, Sobesky R, Bréchot C, Pol S.

J Hepatol. 2003;39 Suppl 1:S151-9. Review. No abstract available. PMID: 14708695 [PubMed - indexed for MEDLINE]Related articles

Alcohol and hepatitis C virus core protein additively increase lipid peroxidation and synergistically trigger hepatic cytokine expression in a transgenic mouse model.

Perlemuter G, Lettéron P, Carnot F, Zavala F, Pessayre D, Nalpas B, Bréchot C.

J Hepatol. 2003 Dec;39(6):1020-7.PMID: 14642621 [PubMed - indexed for MEDLINE]Related articles

Gene therapy of hepatocarcinoma: a long way from the concept to the therapeutical impact.

Gérolami R, Uch R, Bréchot C, Mannoni P, Bagnis C.

Cancer Gene Ther. 2003 Sep;10(9):649-60. Review.PMID: 12944984 [PubMed - indexed for MEDLINE]Related articles

HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway.

Simon MT, Pauloin A, Normand G, Lieu HT, Mouly H, Pivert G, Carnot F, Tralhao JG, Brechot C, Christa L.

FASEB J. 2003 Aug;17(11):1441-50.PMID: 12890698 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection.

Iavarone M, Trabut JB, Delpuech O, Carnot F, Colombo M, Kremsdorf D, Bréchot C, Thiers V.

J Hepatol. 2003 Aug;39(2):253-61.PMID: 12873823 [PubMed - indexed for MEDLINE]Related articles

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

Paterlini-Bréchot P, Saigo K, Murakami Y, Chami M, Gozuacik D, Mugnier C, Lagorce D, Bréchot C.

Oncogene. 2003 Jun 19;22(25):3911-6.PMID: 12813464 [PubMed - indexed for MEDLINE]Related articles

INSERM fosters researches on infectious diseases.

Bréchot C.

Infect Genet Evol. 2002 Jul;1(4):311-2. No abstract available. PMID: 12798011 [PubMed - indexed for MEDLINE]Related articles

New research actions and organizations in France.

Brechot C.

Hepatology. 2003 May;37(5):970-1. Review. No abstract available. PMID: 12717375 [PubMed - indexed for MEDLINE]Related articles

Hepatitis C virus biology.

Giannini C, Bréchot C.

Cell Death Differ. 2003 Jan;10 Suppl 1:S27-38. Review.PMID: 12655344 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver cell polyploidization: a pivotal role for binuclear hepatocytes.

Guidotti JE, Brégerie O, Robert A, Debey P, Brechot C, Desdouets C.

J Biol Chem. 2003 May 23;278(21):19095-101. Epub 2003 Mar 7.PMID: 12626502 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative fluorescence imaging approach for the study of polyploidization in hepatocytes.

Lamas E, Chassoux D, Decaux JF, Brechot C, Debey P.

J Histochem Cytochem. 2003 Mar;51(3):319-30.PMID: 12588960 [PubMed - indexed for MEDLINE]Related articlesFree article

The expression of hepatitis B spliced protein (HBSP) encoded by a spliced hepatitis B virus RNA is associated with viral replication and liver fibrosis.

Soussan P, Tuveri R, Nalpas B, Garreau F, Zavala F, Masson A, Pol S, Brechot C, Kremsdorf D.

J Hepatol. 2003 Mar;38(3):343-8.PMID: 12586301 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated anti insulin-like growth factor I gene transfer for the treatment of hepatocellular carcinoma.

Lafarge-Frayssinet C, Martin C, Van Binh PN, Achard-Ellouk S, Duc HT, Frayssinet C, Cardoso G, Desauty G, Warnet JM, Bréchot C, Sarasin A.

Anticancer Res. 2002 Nov-Dec;22(6C):3895-904.PMID: 12553010 [PubMed - indexed for MEDLINE]Related articles