PubMed

Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study.

Palmer ND, Langefeld CD, Ziegler JT, Hsu F, Haffner SM, Fingerlin T, Norris JM, Chen YI, Rich SS, Haritunians T, Taylor KD, Bergman RN, Rotter JI, Bowden DW.

Diabetologia. 2009 Nov 10. [Epub ahead of print]PMID: 19902172 [PubMed - as supplied by publisher]Related articles

Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: African American-Diabetes Heart Study.

Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Xu J, Langefeld CD, Freedman BI.

Diabetes Care. 2009 Oct 13. [Epub ahead of print]PMID: 19825824 [PubMed - as supplied by publisher]Related articles

Variant in the 3' Region of the IkappaBalpha Gene Associated With Insulin Resistance in Hispanic Americans: The IRAS Family Study.

Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE.

Obesity (Silver Spring). 2009 Oct 1. [Epub ahead of print]PMID: 19798070 [PubMed - as supplied by publisher]Related articles

Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the family investigation of nephropathy and diabetes research group.

Malhotra A, Igo RP Jr, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, Kohn O, Leehey D, Meoni LA, Nelson RG, Nicholas SB, Parekh RS, Rich SS, Chen YD, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Taylor KD, Thornley-Brown D, Zager PG, Horvath A, Hanson RL; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes Metab Res Rev. 2009 Nov;25(8):740-7.PMID: 19795399 [PubMed - in process]Related articles

Potential donor-recipient MYH9 genotype interactions in posttransplant nephrotic syndrome after pediatric kidney transplantation.

Freedman BI, Nagaraj SK, Lin JJ, Gautreaux MD, Bowden DW, Iskandar SS, Stratta RJ, Rogers J, Hartmann EL, Farney AC, Reeves-Daniel AM.

Am J Transplant. 2009 Oct;9(10):2435-40.PMID: 19764949 [PubMed - in process]Related articles

Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.

McDonough CW, Bostrom MA, Lu L, Hicks PJ, Langefeld CD, Divers J, Mychaleckyj JC, Freedman BI, Bowden DW.

Hum Genet. 2009 Aug 19. [Epub ahead of print]PMID: 19690890 [PubMed - as supplied by publisher]Related articles

Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.

Freedman BI, Hicks PJ, Bostrom MA, Comeau ME, Divers J, Bleyer AJ, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.

Nephrol Dial Transplant. 2009 Nov;24(11):3366-71. Epub 2009 Jun 30.PMID: 19567477 [PubMed - in process]Related articles

Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study.

Norris JM, Langefeld CD, Talbert ME, Wing MR, Haritunians T, Fingerlin TE, Hanley AJ, Ziegler JT, Taylor KD, Haffner SM, Chen YD, Bowden DW, Wagenknecht LE.

Obesity (Silver Spring). 2009 Oct;17(10):1932-41. Epub 2009 May 21.PMID: 19461586 [PubMed - in process]Related articles

Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study.

Freedman BI, Bowden DW, Ziegler JT, Langefeld CD, Lehtinen AB, Rudock ME, Lenchik L, Hruska KA, Register TC, Carr JJ.

J Bone Miner Res. 2009 Oct;24(10):1719-27.PMID: 19453255 [PubMed - in process]Related articles

Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans.

Schmitz KJ, Skinner HG, Bautista LE, Fingerlin TE, Langefeld CD, Hicks PJ, Haffner SM, Bryer-Ash M, Wagenknecht LE, Bowden DW, Norris JM, Engelman CD.

Am J Hypertens. 2009 Aug;22(8):867-70. Epub 2009 May 14.PMID: 19444222 [PubMed - indexed for MEDLINE]Related articles

A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).

Rich SS, Goodarzi MO, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, Rotter JI, Chen YD, Wagenknecht LE, Bowden DW, Bergman RN.

Diabetologia. 2009 Jul;52(7):1326-33. Epub 2009 May 9.PMID: 19430760 [PubMed - indexed for MEDLINE]Related articles

The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans.

McDonough CW, Hicks PJ, Lu L, Langefeld CD, Freedman BI, Bowden DW.

Hum Genet. 2009 Aug;126(2):265-75. Epub 2009 Apr 17.PMID: 19373489 [PubMed - indexed for MEDLINE]Related articles

INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.

Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Obesity (Silver Spring). 2009 Aug;17(8):1554-62. Epub 2009 Apr 9.PMID: 19360016 [PubMed - indexed for MEDLINE]Related articles

Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study.

Sutton BS, Palmer ND, Langefeld CD, Xue B, Proctor A, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Diabetes. 2009 Jun;58(6):1457-62. Epub 2009 Mar 26.PMID: 19324939 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW.

Hum Genet. 2009 Jun;125(5-6):615-26. Epub 2009 Mar 26.PMID: 19322589 [PubMed - indexed for MEDLINE]Related articles

Ethnic variation in the correlation between random serum glucose concentration and glycated haemoglobin.

Bleyer AJ, Hire D, Russell GB, Xu J, Divers J, Shihabi Z, Bowden DW, Freedman BI.

Diabet Med. 2009 Feb;26(2):128-33.PMID: 19236614 [PubMed - indexed for MEDLINE]Related articles

Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans.

Leak TS, Perlegas PS, Smith SG, Keene KL, Hicks PJ, Langefeld CD, Mychaleckyj JC, Rich SS, Kirk JK, Freedman BI, Bowden DW, Sale MM.

Ann Hum Genet. 2009 Mar;73(2):152-9. Epub 2009 Jan 23.PMID: 19183347 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.

Freedman BI, Hicks PJ, Bostrom MA, Cunningham ME, Liu Y, Divers J, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.

Kidney Int. 2009 Apr;75(7):736-45. Epub 2009 Jan 28.PMID: 19177153 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study.

Lehtinen AB, Daniel KR, Shah SA, Nelson MR, Ziegler JT, Freedman BI, Carr JJ, Herrington DM, Langefeld CD, Bowden DW.

Ann Noninvasive Electrocardiol. 2009 Jan;14(1):72-9.PMID: 19149796 [PubMed - indexed for MEDLINE]Related articles

Functional ENTPD1 polymorphisms in African Americans with diabetes and end-stage renal disease.

Friedman DJ, Talbert ME, Bowden DW, Freedman BI, Mukanya Y, Enjyoji K, Robson SC.

Diabetes. 2009 Apr;58(4):999-1006. Epub 2008 Dec 18.PMID: 19095759 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.

Talbert ME, Langefeld CD, Ziegler J, Mychaleckyj JC, Haffner SM, Norris JM, Bowden DW.

Hum Genet. 2009 Mar;125(2):153-62. Epub 2008 Dec 13.PMID: 19083014 [PubMed - indexed for MEDLINE]Related articles

Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy.

Bostrom MA, Freedman BI, Langefeld CD, Liu L, Hicks PJ, Bowden DW.

Diabetes. 2009 Feb;58(2):499-504. Epub 2008 Dec 3.PMID: 19056609 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study.

McKimmie RL, Daniel KR, Carr JJ, Bowden DW, Freedman BI, Register TC, Hsu FC, Lohman KK, Weinberg RB, Wagenknecht LE.

Am J Gastroenterol. 2008 Dec;103(12):3029-35. Epub 2008 Oct 3.PMID: 18853970 [PubMed - indexed for MEDLINE]Related articles

Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy.

Zhang D, Freedman BI, Flekac M, Santos E, Hicks PJ, Bowden DW, Efendic S, Brismar K, Gu HF.

Am J Nephrol. 2009;29(3):244-51. Epub 2008 Sep 19.PMID: 18802326 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans.

Palmer ND, Langefeld CD, Bryer-Ash M, Rotter JI, Taylor KD, Bowden DW.

J Clin Endocrinol Metab. 2008 Dec;93(12):4979-83. Epub 2008 Sep 16.PMID: 18796522 [PubMed - indexed for MEDLINE]Related articles

MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.

Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, Bowden DW, Oleksyk T, McKenzie LM, Kajiyama H, Ahuja TS, Berns JS, Briggs W, Cho ME, Dart RA, Kimmel PL, Korbet SM, Michel DM, Mokrzycki MH, Schelling JR, Simon E, Trachtman H, Vlahov D, Winkler CA.

Nat Genet. 2008 Oct;40(10):1175-84. Epub 2008 Sep 14.PMID: 18794856 [PubMed - indexed for MEDLINE]Related articles

Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.

Rudock ME, Liu Y, Ziegler JT, Allen SG, Lehtinen AB, Freedman BI, Carr JJ, Langefeld CD, Bowden DW.

Atherosclerosis. 2009 Apr;203(2):459-65. Epub 2008 Jul 26.PMID: 18768181 [PubMed - indexed for MEDLINE]Related articles

Heritability of the severity of diabetic retinopathy: the FIND-Eye study.

Arar NH, Freedman BI, Adler SG, Iyengar SK, Chew EY, Davis MD, Satko SG, Bowden DW, Duggirala R, Elston RC, Guo X, Hanson RL, Igo RP Jr, Ipp E, Kimmel PL, Knowler WC, Molineros J, Nelson RG, Pahl MV, Quade SR, Rasooly RS, Rotter JI, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Zager PG, Abboud HE; Family Investigation of Nephropathy and Diabetes Research Group.

Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3839-45.PMID: 18765632 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.

Keene KL, Mychaleckyj JC, Leak TS, Smith SG, Perlegas PS, Divers J, Langefeld CD, Freedman BI, Bowden DW, Sale MM.

Hum Genet. 2008 Sep;124(2):147-54. Epub 2008 Jul 25. Erratum in: Hum Genet. 2008 Sep;124(2):197-8. PMID: 18654799 [PubMed - indexed for MEDLINE]Related articles

Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes.

Liu Y, Freedman BI, Burdon KP, Langefeld CD, Howard T, Herrington D, Goff DC Jr, Bowden DW, Wagenknecht LE, Hedrick CC, Rich SS.

Am J Kidney Dis. 2008 Aug;52(2):242-50. Epub 2008 Mar 25.PMID: 18640486 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

Bento JL, Palmer ND, Zhong M, Roh B, Lewis JP, Wing MR, Pandya H, Freedman BI, Langefeld CD, Rich SS, Bowden DW, Mychaleckyj JC.

Genomics. 2008 Oct;92(4):226-34. Epub 2008 Aug 9.PMID: 18602983 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans.

Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, Wagenknecht LE, Bowden DW, Norris JM.

J Clin Endocrinol Metab. 2008 Sep;93(9):3381-8. Epub 2008 Jul 1.PMID: 18593774 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.

Hicks PJ, Staten JL, Palmer ND, Langefeld CD, Ziegler JT, Keene KL, Sale MM, Bowden DW, Freedman BI.

Am J Nephrol. 2008;28(6):914-20. Epub 2008 Jun 26.PMID: 18580054 [PubMed - indexed for MEDLINE]Related articles

Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population.

Leak TS, Mychaleckyj JC, Smith SG, Keene KL, Gordon CJ, Hicks PJ, Freedman BI, Bowden DW, Sale MM.

Hum Genet. 2008 Aug;124(1):63-71. Epub 2008 Jun 17.PMID: 18560894 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study.

Burdon KP, Lehtinen AB, Langefeld CD, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW.

Diab Vasc Dis Res. 2008 Jun;5(2):128-34.PMID: 18537101 [PubMed - indexed for MEDLINE]Related articles

Genetic epidemiology of subclinical cardiovascular disease in the diabetes heart study.

Bowden DW, Lehtinen AB, Ziegler JT, Rudock ME, Xu J, Wagenknecht LE, Herrington DM, Rich SS, Freedman BI, Carr JJ, Langefeld CD.

Ann Hum Genet. 2008 Sep;72(Pt 5):598-610. Epub 2008 Apr 29.PMID: 18460048 [PubMed - indexed for MEDLINE]Related articles

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW.

Diabetes. 2008 Aug;57(8):2220-5. Epub 2008 Apr 28.PMID: 18443202 [PubMed - indexed for MEDLINE]Related articlesFree article

ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: the multi-ethnic study of atherosclerosis (MESA).

Bielinski SJ, Pankow JS, Li N, Hsu FC, Adar SD, Jenny NS, Bowden DW, Wasserman BA, Arnett D.

Atherosclerosis. 2008 Dec;201(2):339-44. Epub 2008 Mar 14.PMID: 18420209 [PubMed - indexed for MEDLINE]Related articles

Associations between electrocardiographic interval durations and coronary artery calcium scores: the Diabetes Heart Study.

Nelson MR, Daniel KR, Carr JJ, Freedman BI, Prineas RJ, Bowden DW, Herrington DM.

Pacing Clin Electrophysiol. 2008 Mar;31(3):314-21.PMID: 18307626 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage scans for renal function and albuminuria in Type 2 diabetes mellitus: the Diabetes Heart Study.

Freedman BI, Bowden DW, Rich SS, Xu J, Wagenknecht LE, Ziegler J, Hicks PJ, Langefeld CD.

Diabet Med. 2008 Mar;25(3):268-76.PMID: 18307454 [PubMed - indexed for MEDLINE]Related articles

Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.

Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Herrington DM, Freedman BI, Rich SS, Bowden DW, Sale MM.

Hum Genet. 2008 May;123(4):333-41. Epub 2008 Feb 28.PMID: 18305958 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

Chromogranin A polymorphisms are associated with hypertensive renal disease.

Salem RM, Cadman PE, Chen Y, Rao F, Wen G, Hamilton BA, Rana BK, Smith DW, Stridsberg M, Ward HJ, Mahata M, Mahata SK, Bowden DW, Hicks PJ, Freedman BI, Schork NJ, O'Connor DT.

J Am Soc Nephrol. 2008 Mar;19(3):600-14. Epub 2008 Jan 30.PMID: 18235090 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study.

Lehtinen AB, Newton-Cheh C, Ziegler JT, Langefeld CD, Freedman BI, Daniel KR, Herrington DM, Bowden DW.

Diabetes. 2008 Apr;57(4):1108-14. Epub 2008 Jan 30.PMID: 18235038 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy.

Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Freedman BI, Rich SS, Bowden DW, Sale MM.

Diabetes. 2008 Apr;57(4):1057-62. Epub 2008 Jan 9.PMID: 18184924 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney volume associations with subclinical renal and cardiovascular disease: the Diabetes Heart Study.

Saran AM, Hsu FC, Lohman KK, Carr JJ, Bowden DW, Wagenknecht LE, Freedman BI.

Am J Nephrol. 2008;28(3):366-71. Epub 2007 Dec 5.PMID: 18057869 [PubMed - indexed for MEDLINE]Related articles

Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND).

Schelling JR, Abboud HE, Nicholas SB, Pahl MV, Sedor JR, Adler SG, Arar NH, Bowden DW, Elston RC, Freedman BI, Goddard KA, Guo X, Hanson RL, Ipp E, Iyengar SK, Jun G, Kao WH, Kasinath BS, Kimmel PL, Klag MJ, Knowler WC, Nelson RG, Parekh RS, Quade SR, Rich SS, Saad MF, Scavini M, Smith MW, Taylor K, Winkler CA, Zager PG, Shah VO; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes. 2008 Jan;57(1):235-43. Epub 2007 Nov 14.PMID: 18003762 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.

Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW.

J Clin Endocrinol Metab. 2008 Jan;93(1):304-9. Epub 2007 Oct 30.PMID: 17971425 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcified atherosclerotic plaque and bone mineral density in type 2 diabetes: the diabetes heart study.

Carr JJ, Register TC, Hsu FC, Lohman K, Lenchik L, Bowden DW, Langefeld CD, Xu J, Rich SS, Wagenknecht LE, Freedman BI.

Bone. 2008 Jan;42(1):43-52. Epub 2007 Aug 22.PMID: 17964237 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic factors in diabetic nephropathy.

Freedman BI, Bostrom M, Daeihagh P, Bowden DW.

Clin J Am Soc Nephrol. 2007 Nov;2(6):1306-16. Epub 2007 Oct 17. Review.PMID: 17942768 [PubMed - indexed for MEDLINE]Related articlesFree article