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Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase.
Borradaile NM, Pickering JG.
Am J Physiol Cell Physiol. 2009 Oct 21. [Epub ahead of print]PMID: 19846757 [PubMed - as supplied by publisher]Related articles
Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment.
Aging Cell. 2009 Apr;8(2):100-12.PMID: 19302375 [PubMed - indexed for MEDLINE]Related articles
NAD(+), sirtuins, and cardiovascular disease.
Curr Pharm Des. 2009;15(1):110-7. Review.PMID: 19149606 [PubMed - indexed for MEDLINE]Related articles
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death.
Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE.
J Lipid Res. 2006 Dec;47(12):2726-37. Epub 2006 Sep 7.PMID: 16960261 [PubMed - indexed for MEDLINE]Related articlesFree article
Lipotoxicity in the heart.
Borradaile NM, Schaffer JE.
Curr Hypertens Rep. 2005 Dec;7(6):412-7. Review.PMID: 16386196 [PubMed - indexed for MEDLINE]Related articles
A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death.
Borradaile NM, Buhman KK, Listenberger LL, Magee CJ, Morimoto ET, Ory DS, Schaffer JE.
Mol Biol Cell. 2006 Feb;17(2):770-8. Epub 2005 Nov 30.PMID: 16319173 [PubMed - indexed for MEDLINE]Related articlesFree article
Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes.
Allister EM, Borradaile NM, Edwards JY, Huff MW.
Diabetes. 2005 Jun;54(6):1676-83.PMID: 15919788 [PubMed - indexed for MEDLINE]Related articlesFree article
Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation.
Borradaile NM, de Dreu LE, Huff MW.
Diabetes. 2003 Oct;52(10):2554-61.PMID: 14514640 [PubMed - indexed for MEDLINE]Related articlesFree article
Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation.
Borradaile NM, de Dreu LE, Barrett PH, Behrsin CD, Huff MW.
Biochemistry. 2003 Feb 11;42(5):1283-91.PMID: 12564931 [PubMed - indexed for MEDLINE]Related articles
Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.
Borradaile NM, de Dreu LE, Barrett PH, Huff MW.
J Lipid Res. 2002 Sep;43(9):1544-54.PMID: 12235187 [PubMed - indexed for MEDLINE]Related articlesFree article
Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms.
Borradaile NM, de Dreu LE, Wilcox LJ, Edwards JY, Huff MW.
Biochem J. 2002 Sep 1;366(Pt 2):531-9.PMID: 12030847 [PubMed - indexed for MEDLINE]Related articlesFree article
Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP.
Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW.
J Lipid Res. 2001 May;42(5):725-34.PMID: 11352979 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin.
Borradaile NM, Carroll KK, Kurowska EM.
Lipids. 1999 Jun;34(6):591-8.PMID: 10405973 [PubMed - indexed for MEDLINE]Related articles
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Mol Biol Cell. 2006 Feb; 17(2):770-8.
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