PubMed

JNK inhibition and inflammation after cerebral ischemia.

Benakis C, Bonny C, Hirt L.

Brain Behav Immun. 2009 Nov 10. [Epub ahead of print]PMID: 19903520 [PubMed - as supplied by publisher]Related articles

The JNK-inhibitor XG-102 enhances the neuroprotection of hyperbaric oxygen after cerebral ischaemia in adult rats.

Liu JR, Zhao Y, Patzer A, Staak N, Boehm R, Deuschl G, Culman J, Bonny C, Herdegen T, Eschenfelder C.

Neuropathol Appl Neurobiol. 2009 Oct 22. [Epub ahead of print]PMID: 19849792 [PubMed - as supplied by publisher]Related articles

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis.

Abdelli S, Puyal J, Bielmann C, Buchillier V, Abderrahmani A, Clarke PG, Beckmann JS, Bonny C.

Diabetologia. 2009 Sep;52(9):1871-80. Epub 2009 Jul 16.PMID: 19609503 [PubMed - in process]Related articles

c-Jun N-terminal kinase binding domain-dependent phosphorylation of mitogen-activated protein kinase kinase 4 and mitogen-activated protein kinase kinase 7 and balancing cross-talk between c-Jun N-terminal kinase and extracellular signal-regulated kinase pathways in cortical neurons.

Repici M, Mare L, Colombo A, Ploia C, Sclip A, Bonny C, Nicod P, Salmona M, Borsello T.

Neuroscience. 2009 Mar 3;159(1):94-103. Epub 2008 Dec 14.PMID: 19135136 [PubMed - indexed for MEDLINE]Related articles

The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator.

Wiegler K, Bonny C, Coquoz D, Hirt L.

Cerebrovasc Dis. 2008;26(4):360-6. Epub 2008 Aug 27.PMID: 18728363 [PubMed - indexed for MEDLINE]Related articles

Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels.

Sarre A, Gardier S, Maurer F, Bonny C, Raddatz E.

Mol Cell Biochem. 2008 Jun;313(1-2):133-8. Epub 2008 Apr 17.PMID: 18418700 [PubMed - indexed for MEDLINE]Related articles

Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases.

Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.

FASEB J. 2008 Jun;22(6):1905-13. Epub 2008 Feb 8.PMID: 18263705 [PubMed - indexed for MEDLINE]Related articlesFree article

D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats.

Esneault E, Castagne V, Moser P, Bonny C, Bernaudin M.

Neuroscience. 2008 Mar 18;152(2):308-20. Epub 2008 Jan 4.PMID: 18262367 [PubMed - indexed for MEDLINE]Related articles

Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation.

Repici M, Centeno C, Tomasi S, Forloni G, Bonny C, Vercelli A, Borsello T.

Neuroscience. 2007 Nov 30;150(1):40-9. Epub 2007 Aug 28.PMID: 17900813 [PubMed - indexed for MEDLINE]Related articles

The epidemiology and virology of hepatitis C virus genotype 5 in central France.

Abergel A, Ughetto S, Dubost S, Bonny C, Aublet-Cuvelier B, Delarocque-Astagneau E, Bailly JL, Bommelaer G, Casanova S, Delteil J, Deny P, Laurichesse H, Odent-Malaure H, Roussel J, Peigue-Lafeuille H, Henquell C.

Aliment Pharmacol Ther. 2007 Nov 15;26(10):1437-46. Epub 2007 Sep 26.PMID: 17900267 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-permeable peptides induce dose- and length-dependent cytotoxic effects.

Cardozo AK, Buchillier V, Mathieu M, Chen J, Ortis F, Ladrière L, Allaman-Pillet N, Poirot O, Kellenberger S, Beckmann JS, Eizirik DL, Bonny C, Maurer F.

Biochim Biophys Acta. 2007 Sep;1768(9):2222-34. Epub 2007 Jun 14.PMID: 17626783 [PubMed - indexed for MEDLINE]Related articles

The c-Jun N-terminal kinase JNK participates in cytokine- and isolation stress-induced rat pancreatic islet apoptosis.

Abdelli S, Abderrahmani A, Hering BJ, Beckmann JS, Bonny C.

Diabetologia. 2007 Aug;50(8):1660-9. Epub 2007 Jun 9.PMID: 17558486 [PubMed - indexed for MEDLINE]Related articles

Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase.

Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL.

J Virol. 2007 Jul;81(13):6984-92. Epub 2007 May 2.PMID: 17475657 [PubMed - indexed for MEDLINE]Related articlesFree article

[Iron overload and chronic liver diseases]

Abergel A, Ruivard M, Bonny C.

Rev Prat. 2006 Dec 15;56(19):2130-4. French. PMID: 17416050 [PubMed - indexed for MEDLINE]Related articles

A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo.

Milano G, Morel S, Bonny C, Samaja M, von Segesser LK, Nicod P, Vassalli G.

Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1828-35. Epub 2006 Dec 8.PMID: 17158645 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals.

Wang J, Ruel J, Ladrech S, Bonny C, van de Water TR, Puel JL.

Mol Pharmacol. 2007 Mar;71(3):654-66. Epub 2006 Nov 28.PMID: 17132689 [PubMed - indexed for MEDLINE]Related articlesFree article

Peginterferon alpha-2b plus ribavirin for treatment of chronic hepatitis C with severe fibrosis: a multicentre randomized controlled trial comparing two doses of peginterferon alpha-2b.

Abergel A, Hezode C, Leroy V, Barange K, Bronowicki JP, Tran A, Alric L, Castera L, Bernard PH, Henquell C, Lafeuille H, Ughetto S, Darcha C, Chevallier M, Martineau N, Dubost S, Randl K, Dhumeaux D, Bommelaer G, Bonny C; French multicenter study group.

J Viral Hepat. 2006 Dec;13(12):811-20.PMID: 17109680 [PubMed - indexed for MEDLINE]Related articles

Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.

Eshraghi AA, Wang J, Adil E, He J, Zine A, Bublik M, Bonny C, Puel JL, Balkany TJ, Van De Water TR.

Hear Res. 2007 Apr;226(1-2):168-77. Epub 2006 Nov 13.PMID: 17098385 [PubMed - indexed for MEDLINE]Related articles

Homogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates.

Guenat S, Rouleau N, Bielmann C, Bedard J, Maurer F, Allaman-Pillet N, Nicod P, Bielefeld-Sévigny M, Beckmann JS, Bonny C, Bossé R, Roduit R.

J Biomol Screen. 2006 Dec;11(8):1015-26. Epub 2006 Nov 7.PMID: 17092917 [PubMed - indexed for MEDLINE]Related articles

Blocking stress signaling pathways with cell permeable peptides.

Bonny C.

Adv Exp Med Biol. 2006;588:133-43. Review.PMID: 17089885 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of interferon plus ribavirin combination in the treatment of naive patients with hepatitis C virus type 5. A French multicentre retrospective study.

Bonny C, Fontaine H, Poynard T, Hézode C, Larrey D, Marcellin P, Bourlière M, Bronowicki JP, Merle P, Zarski JP, Sapey T, Guillemard C, Ughetto S, Henquell C, Nicolas C, Roche C, Randl K, Bommelaer G, Abergel A.

Aliment Pharmacol Ther. 2006 Aug 15;24(4):593-600. Erratum in: Aliment Pharmacol Ther. 2006 Oct 15;24(8):1268. PMID: 16907892 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons.

Centeno C, Repici M, Chatton JY, Riederer BM, Bonny C, Nicod P, Price M, Clarke PG, Papa S, Franzoso G, Borsello T.

Cell Death Differ. 2007 Feb;14(2):240-53. Epub 2006 Jun 23.PMID: 16794604 [PubMed - indexed for MEDLINE]Related articlesFree article

D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma.

Eshraghi AA, He J, Mou CH, Polak M, Zine A, Bonny C, Balkany TJ, Van De Water TR.

Otol Neurotol. 2006 Jun;27(4):504-11.PMID: 16791042 [PubMed - indexed for MEDLINE]Related articles

Brief reoxygenation episodes during chronic hypoxia enhance posthypoxic recovery of LV function: role of mitogen-activated protein kinase signaling pathways.

Morel S, Milano G, Ludunge KM, Corno AF, Samaja M, Fleury S, Bonny C, Kappenberger L, von Segesser LK, Vassalli G.

Basic Res Cardiol. 2006 Jul;101(4):336-45. Epub 2006 May 16.PMID: 16705469 [PubMed - indexed for MEDLINE]Related articles

A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR.

J Neurosci. 2006 Mar 29;26(13):3551-60.PMID: 16571763 [PubMed - indexed for MEDLINE]Related articlesFree article

Significance of patient-controlled sedation during colonoscopy. Results from a prospective randomized controlled study.

Crepeau T, Poincloux L, Bonny C, Lighetto S, Jaffeux P, Artigue F, Walleckx P, Bazin JE, Dapoigny M, Bommelaer G.

Gastroenterol Clin Biol. 2005 Nov;29(11):1090-6.PMID: 16505753 [PubMed - indexed for MEDLINE]Related articlesFree article

A unique set of SH3-SH3 interactions controls IB1 homodimerization.

Kristensen O, Guenat S, Dar I, Allaman-Pillet N, Abderrahmani A, Ferdaoussi M, Roduit R, Maurer F, Beckmann JS, Kastrup JS, Gajhede M, Bonny C.

EMBO J. 2006 Feb 22;25(4):785-97. Epub 2006 Feb 2.PMID: 16456539 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of outcome in patients with cirrhosis and ascites following treatment with albumin or a synthetic colloid: a randomised controlled pilot trail.

Moreau R, Valla DC, Durand-Zaleski I, Bronowicki JP, Durand F, Chaput JC, Dadamessi I, Silvain C, Bonny C, Oberti F, Gournay J, Lebrec D, Grouin JM, Guémas E, Golly D, Padrazzi B, Tellier Z.

Liver Int. 2006 Feb;26(1):46-54.PMID: 16420509 [PubMed - indexed for MEDLINE]Related articles

D-TAT transporter as an ocular peptide delivery system.

Schorderet DF, Manzi V, Canola K, Bonny C, Arsenijevic Y, Munier FL, Maurer F.

Clin Experiment Ophthalmol. 2005 Dec;33(6):628-35.PMID: 16402957 [PubMed - indexed for MEDLINE]Related articles

Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.

Larsen L, Størling J, Darville M, Eizirik DL, Bonny C, Billestrup N, Mandrup-Poulsen T.

Diabetologia. 2005 Dec;48(12):2582-90. Epub 2005 Nov 11.PMID: 16283237 [PubMed - indexed for MEDLINE]Related articles

[Role of intracellular signalling pathways in the development of type 1 diabetes]

Bonny C.

Rev Med Suisse. 2005 Apr 27;1(17):1153-6. French. PMID: 15941087 [PubMed - indexed for MEDLINE]Related articles

Targeting the JNK pathway as a therapeutic protective strategy for nervous system diseases.

Bonny C, Borsello T, Zine A.

Rev Neurosci. 2005;16(1):57-67. Review.PMID: 15810654 [PubMed - indexed for MEDLINE]Related articles

Antitumorigenic effect of proteasome inhibitors on insulinoma cells.

Størling J, Allaman-Pillet N, Karlsen AE, Billestrup N, Bonny C, Mandrup-Poulsen T.

Endocrinology. 2005 Apr;146(4):1718-26. Epub 2004 Dec 23.PMID: 15618349 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure.

Abdelli S, Ansite J, Roduit R, Borsello T, Matsumoto I, Sawada T, Allaman-Pillet N, Henry H, Beckmann JS, Hering BJ, Bonny C.

Diabetes. 2004 Nov;53(11):2815-23.PMID: 15504961 [PubMed - indexed for MEDLINE]Related articlesFree article

Histological response in patients treated by interferon plus ribavirin for hepatitis C virus-related severe fibrosis.

Abergel A, Darcha C, Chevallier M, Ughetto S, Henquell C, Pol S, de Ledinghen V, Canva V, Bronowicki JP, Tran A, Martineau N, Lafeuille H, Dechelotte P, Bommelaer G, Bonny C; French Multicentre Study Group.

Eur J Gastroenterol Hepatol. 2004 Nov;16(11):1219-27.PMID: 15489585 [PubMed - indexed for MEDLINE]Related articles

Circadian regulation of islet genes involved in insulin production and secretion.

Allaman-Pillet N, Roduit R, Oberson A, Abdelli S, Ruiz J, Beckmann JS, Schorderet DF, Bonny C.

Mol Cell Endocrinol. 2004 Oct 29;226(1-2):59-66.PMID: 15489006 [PubMed - indexed for MEDLINE]Related articles

A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells.

Michod D, Yang JY, Chen J, Bonny C, Widmann C.

Oncogene. 2004 Nov 25;23(55):8971-8.PMID: 15467750 [PubMed - indexed for MEDLINE]Related articles

Profiling treatment-specific post-translational modifications in a complex proteome with subtractive substrate phage display.

Tenzer A, Hofstetter B, Sauser C, Bodis S, Schubiger AP, Bonny C, Pruschy M.

Proteomics. 2004 Sep;4(9):2796-804.PMID: 15352253 [PubMed - indexed for MEDLINE]Related articles

D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia.

Hirt L, Badaut J, Thevenet J, Granziera C, Regli L, Maurer F, Bonny C, Bogousslavsky J.

Stroke. 2004 Jul;35(7):1738-43. Epub 2004 Jun 3.PMID: 15178829 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of cell-permeable peptides to prevent neuronal degeneration.

Borsello T, Bonny C.

Trends Mol Med. 2004 May;10(5):239-44. Review.PMID: 15121051 [PubMed - indexed for MEDLINE]Related articles

[Medical practices and expectations of general practitioners in relation to hepatitis C virus infection in the Auvergne region]

Bonny C, Rayssiguier R, Ughetto S, Aublet-Cuvelier B, Baranger J, Blanchet G, Delteil J, Hautefeuille P, Lapalus F, Montanier P, Bommelaer G, Abergel A.

Gastroenterol Clin Biol. 2003 Nov;27(11):1021-5. French. PMID: 14732848 [PubMed - indexed for MEDLINE]Related articlesFree article

Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein.

Dar I, Bonny C, Pedersen JT, Gajhede M, Kristensen O.

Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2300-2. Epub 2003 Nov 27.PMID: 14646101 [PubMed - indexed for MEDLINE]Related articles

The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines.

Nikulina MA, Sandhu N, Shamim Z, Andersen NA, Oberson A, Dupraz P, Thorens B, Karlsen AE, Bonny C, Mandrup-Poulsen T.

Cytokine. 2003 Oct;24(1-2):13-24.PMID: 14561487 [PubMed - indexed for MEDLINE]Related articles

Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.

Allaman-Pillet N, Størling J, Oberson A, Roduit R, Negri S, Sauser C, Nicod P, Beckmann JS, Schorderet DF, Mandrup-Poulsen T, Bonny C.

J Biol Chem. 2003 Dec 5;278(49):48720-6. Epub 2003 Sep 24.PMID: 14507925 [PubMed - indexed for MEDLINE]Related articlesFree article

A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.

Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel JL, Zine A.

J Neurosci. 2003 Sep 17;23(24):8596-607.PMID: 13679429 [PubMed - indexed for MEDLINE]Related articlesFree article

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia.

Borsello T, Clarke PG, Hirt L, Vercelli A, Repici M, Schorderet DF, Bogousslavsky J, Bonny C.

Nat Med. 2003 Sep;9(9):1180-6. Epub 2003 Aug 24.PMID: 12937412 [PubMed - indexed for MEDLINE]Related articles

Induction of apoptosis in human corneal and HeLa cells by mutated BIGH3.

Morand S, Buchillier V, Maurer F, Bonny C, Arsenijevic Y, Munier FL, Schorderet DF.

Invest Ophthalmol Vis Sci. 2003 Jul;44(7):2973-9.PMID: 12824240 [PubMed - indexed for MEDLINE]Related articlesFree article

[Polycystic liver disease and its main complications]

Rosenfeld L, Bonny C, Kallita M, Heng AE, Deteix P, Bommelaer G, Abergel A.

Gastroenterol Clin Biol. 2002 Dec;26(12):1097-106. Review. French. No abstract available. PMID: 12520197 [PubMed - indexed for MEDLINE]Related articles

[Radiofrequency ablation of hepatocellular carcinoma in patients with cirrhosis]

Bonny C, Abergel A, Gayard P, Chouzet S, Ughetto S, Slim K, Rosenfeld L, Guillon R, Poincloux L, Bommelaer G.

Gastroenterol Clin Biol. 2002 Aug-Sep;26(8-9):735-41. French. PMID: 12434078 [PubMed - indexed for MEDLINE]Related articlesFree article

Large Family With Maturity-Onset Diabetes of the Young and a Novel V121I Mutation in HNF4A.

Monney CT, Kaltenrieder V, Cousin P, Bonny C, Schorderet DF.

Hum Mutat. 2002 Sep;20(3):230-1.PMID: 12203996 [PubMed - indexed for MEDLINE]Related articles