PubMed

Eating Slowly Increases the Postprandial Response of the Anorexigenic Gut Hormones, Peptide YY and Glucagon-Like Peptide-1.

Kokkinos A, le Roux CW, Alexiadou K, Tentolouris N, Vincent RP, Kyriaki D, Perrea D, Ghatei MA, Bloom SR, Katsilambros N.

J Clin Endocrinol Metab. 2009 Oct 29. [Epub ahead of print]PMID: 19875483 [PubMed - as supplied by publisher]Related articles

Serum molecular signatures of weight change during early breast cancer chemotherapy.

Keun HC, Sidhu J, Pchejetski D, Lewis JS, Marconell H, Patterson M, Bloom SR, Amber V, Coombes RC, Stebbing J.

Clin Cancer Res. 2009 Nov 1;15(21):6716-23. Epub 2009 Oct 27.PMID: 19861449 [PubMed - in process]Related articles

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin.

Ashby DR, Gale DP, Busbridge M, Murphy KG, Duncan ND, Cairns TD, Taube DH, Bloom SR, Tam FW, Chapman R, Maxwell PH, Choi P.

Haematologica. 2009 Oct 14. [Epub ahead of print]PMID: 19833632 [PubMed - as supplied by publisher]Related articlesFree article

The Gut Hormone Response Following Roux-en-Y Gastric Bypass: Cross-sectional and Prospective Study.

Pournaras DJ, Osborne A, Hawkins SC, Mahon D, Ghatei MA, Bloom SR, Welbourn R, le Roux CW.

Obes Surg. 2009 Oct 14. [Epub ahead of print]PMID: 19826888 [PubMed - as supplied by publisher]Related articles

Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis.

Jayasena CN, Nijher GM, Chaudhri OB, Murphy KG, Ranger A, Lim A, Patel D, Mehta A, Todd C, Ramachandran R, Salem V, Stamp GW, Donaldson M, Ghatei MA, Bloom SR, Dhillo WS.

J Clin Endocrinol Metab. 2009 Nov;94(11):4315-23. Epub 2009 Oct 9.PMID: 19820030 [PubMed - in process]Related articles

Ghrelin and peptide YY (PYY) profiles in gastrointestinal tissues and the circulation of the rat during pregnancy and lactation.

Taylor VJ, Patterson M, Ghatei MA, Bloom SR, Wilson CA.

Peptides. 2009 Sep 22. [Epub ahead of print]PMID: 19778563 [PubMed - as supplied by publisher]Related articles

Cerebral activation by fasting induces lactate accumulation in the hypothalamus.

Violante IR, Anastasovska J, Sanchez-Canon GJ, Rodrigues TB, Righi V, Nieto-Charques L, Parkinson JR, Bloom SR, Bell JD, Cerdán S.

Magn Reson Med. 2009 Aug;62(2):279-83.PMID: 19526502 [PubMed - indexed for MEDLINE]Related articles

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance.

Semjonous NM, Smith KL, Parkinson JR, Gunner DJ, Liu YL, Murphy KG, Ghatei MA, Bloom SR, Small CJ.

Int J Obes (Lond). 2009 Jul;33(7):775-85. Epub 2009 Jun 2.PMID: 19488048 [PubMed - in process]Related articles

Hypothalamic regulation of food intake and clinical therapeutic applications.

Simpson KA, Martin NM, Bloom SR.

Arq Bras Endocrinol Metabol. 2009 Mar;53(2):120-8.PMID: 19466203 [PubMed - in process]Related articlesFree article

Relaxin-3 and its role in neuroendocrine function.

McGowan BM, Stanley SA, Ghatei MA, Bloom SR.

Ann N Y Acad Sci. 2009 Apr;1160:250-5.PMID: 19416197 [PubMed - indexed for MEDLINE]Related articles

The future of health insurance for children with special health care needs.

Newacheck PW, Houtrow AJ, Romm DL, Kuhlthau KA, Bloom SR, Van Cleave JM, Perrin JM.

Pediatrics. 2009 May;123(5):e940-7.PMID: 19403486 [PubMed - indexed for MEDLINE]Related articles

Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment.

Ashby DR, Ford HE, Wynne KJ, Wren AM, Murphy KG, Busbridge M, Brown EA, Taube DH, Ghatei MA, Tam FW, Bloom SR, Choi P.

Kidney Int. 2009 Jul;76(2):199-206. Epub 2009 Apr 22.PMID: 19387475 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic injection of oxyntomodulin suppresses circulating ghrelin-like immunoreactivity.

Patterson M, Murphy KG, Patel SR, Patel NA, Greenwood HC, Cooke JH, Campbell D, Bewick GA, Ghatei MA, Bloom SR.

Endocrinology. 2009 Aug;150(8):3513-20. Epub 2009 Apr 9.PMID: 19359390 [PubMed - indexed for MEDLINE]Related articles

Kisspeptin-54 at high doses acutely induces testicular degeneration in adult male rats via central mechanisms.

Thompson EL, Amber V, Stamp GW, Patterson M, Curtis AE, Cooke JH, Appleby GF, Dhillo WS, Ghatei MA, Bloom SR, Murphy KG.

Br J Pharmacol. 2009 Feb;156(4):609-25.PMID: 19226253 [PubMed - indexed for MEDLINE]Related articles

Peripheral and central administration of xenin and neurotensin suppress food intake in rodents.

Cooke JH, Patterson M, Patel SR, Smith KL, Ghatei MA, Bloom SR, Murphy KG.

Obesity (Silver Spring). 2009 Jun;17(6):1135-43. Epub 2009 Feb 12.PMID: 19214175 [PubMed - indexed for MEDLINE]Related articles

Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease.

Ashby DR, Gale DP, Busbridge M, Murphy KG, Duncan ND, Cairns TD, Taube DH, Bloom SR, Tam FW, Chapman RS, Maxwell PH, Choi P.

Kidney Int. 2009 May;75(9):976-81. Epub 2009 Feb 11.PMID: 19212416 [PubMed - indexed for MEDLINE]Related articles

Mice with hyperghrelinemia are hyperphagic and glucose intolerant and have reduced leptin sensitivity.

Bewick GA, Kent A, Campbell D, Patterson M, Ghatei MA, Bloom SR, Gardiner JV.

Diabetes. 2009 Apr;58(4):840-6. Epub 2009 Jan 16.PMID: 19151202 [PubMed - indexed for MEDLINE]Related articlesFree article

Gastrointestinal satiety signals.

Chaudhri OB, Field BC, Bloom SR.

Int J Obes (Lond). 2008 Dec;32 Suppl 7:S28-31. Review.PMID: 19136988 [PubMed - indexed for MEDLINE]Related articles

Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogs.

Druce MR, Minnion JS, Field BC, Patel SR, Shillito JC, Tilby M, Beale KE, Murphy KG, Ghatei MA, Bloom SR.

Endocrinology. 2009 Apr;150(4):1712-22. Epub 2008 Dec 12.PMID: 19074579 [PubMed - indexed for MEDLINE]Related articles

Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI).

Parkinson JR, Chaudhri OB, Kuo YT, Field BC, Herlihy AH, Dhillo WS, Ghatei MA, Bloom SR, Bell JD.

Neuroimage. 2009 Feb 1;44(3):1022-31. Epub 2008 Oct 15.PMID: 18983926 [PubMed - indexed for MEDLINE]Related articles

Gut hormones and appetite control.

Hameed S, Dhillo WS, Bloom SR.

Oral Dis. 2009 Jan;15(1):18-26. Epub 2008 Oct 17. Review.PMID: 18939959 [PubMed - indexed for MEDLINE]Related articles

The effects of pancreatic polypeptide on locomotor activity and food intake in mice.

Liu YL, Semjonous NM, Murphy KG, Ghatei MA, Bloom SR.

Int J Obes (Lond). 2008 Nov;32(11):1712-5. Epub 2008 Sep 9.PMID: 18779824 [PubMed - indexed for MEDLINE]Related articles

Role of gut hormones in obesity.

Jayasena CN, Bloom SR.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):769-87, xi. Review.PMID: 18775363 [PubMed - indexed for MEDLINE]Related articles

Overexpression of CART in the PVN increases food intake and weight gain in rats.

Smith KL, Gardiner JV, Ward HL, Kong WM, Murphy KG, Martin NM, Ghatei MA, Bloom SR.

Obesity (Silver Spring). 2008 Oct;16(10):2239-44. Epub 2008 Jul 31.PMID: 18719668 [PubMed - indexed for MEDLINE]Related articles

The thyroid hormone derivative 3-iodothyronamine increases food intake in rodents.

Dhillo WS, Bewick GA, White NE, Gardiner JV, Thompson EL, Bataveljic A, Murphy KG, Roy D, Patel NA, Scutt JN, Armstrong A, Ghatei MA, Bloom SR.

Diabetes Obes Metab. 2009 Mar;11(3):251-60. Epub 2008 Jul 29.PMID: 18671794 [PubMed - indexed for MEDLINE]Related articles

Kisspeptins and the control of gonadotropin secretion in humans.

Jayasena CN, Dhillo WS, Bloom SR.

Peptides. 2009 Jan;30(1):76-82. Epub 2008 Jul 4.PMID: 18656511 [PubMed - indexed for MEDLINE]Related articles

No evidence of an additive inhibitory feeding effect following PP and PYY 3-36 administration.

Neary NM, McGowan BM, Monteiro MP, Jesudason DR, Ghatei MA, Bloom SR.

Int J Obes (Lond). 2008 Sep;32(9):1438-40. Epub 2008 Jul 8.PMID: 18607381 [PubMed - indexed for MEDLINE]Related articles

Long-acting octreotide treatment causes a sustained decrease in ghrelin concentrations but does not affect weight, behaviour and appetite in subjects with Prader-Willi syndrome.

De Waele K, Ishkanian SL, Bogarin R, Miranda CA, Ghatei MA, Bloom SR, Pacaud D, Chanoine JP.

Eur J Endocrinol. 2008 Oct;159(4):381-8. Epub 2008 Jul 4.PMID: 18603572 [PubMed - indexed for MEDLINE]Related articlesFree article

Gut hormones: a weight off your mind.

Gardiner JV, Jayasena CN, Bloom SR.

J Neuroendocrinol. 2008 Jun;20(6):834-41. Review.PMID: 18601707 [PubMed - indexed for MEDLINE]Related articles

Peptide YY: a gut hormone associated with anorexia during infectious diarrhea in children.

Beck AL, Cabrera L, Pan WK, Cama V, Friedland JS, Ghatei MA, Bloom SR, Lewis J, Gilman RH.

J Pediatr. 2008 Nov;153(5):677-82. Epub 2008 Jun 24.PMID: 18571670 [PubMed - indexed for MEDLINE]Related articles

Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats.

Patel SR, Murphy KG, Thompson EL, Patterson M, Curtis AE, Ghatei MA, Bloom SR.

Endocrinology. 2008 Sep;149(9):4747-54. Epub 2008 Jun 5.PMID: 18535111 [PubMed - indexed for MEDLINE]Related articlesFree article

Relaxin-3 stimulates the hypothalamic-pituitary-gonadal axis.

McGowan BM, Stanley SA, Donovan J, Thompson EL, Patterson M, Semjonous NM, Gardiner JV, Murphy KG, Ghatei MA, Bloom SR.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E278-86. Epub 2008 May 20.PMID: 18492777 [PubMed - indexed for MEDLINE]Related articlesFree article

An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivo.

Keen KL, Wegner FH, Bloom SR, Ghatei MA, Terasawa E.

Endocrinology. 2008 Aug;149(8):4151-7. Epub 2008 May 1.PMID: 18450954 [PubMed - indexed for MEDLINE]Related articlesFree article

The obesity epidemic: pharmacological challenges.

Bloom SR, Kuhajda FP, Laher I, Pi-Sunyer X, Ronnett GV, Tan TM, Weigle DS.

Mol Interv. 2008 Apr;8(2):82-98. Review.PMID: 18403653 [PubMed - indexed for MEDLINE]Related articlesFree article

Preanalytical factors affecting RIA measurement of plasma kisspeptin.

Ramachandran R, Patterson M, Murphy KG, Dhillo WS, Patel S, Kazarian A, Ghatei MA, Bloom SR.

Clin Chem. 2008 Mar;54(3):615-7. No abstract available. PMID: 18310154 [PubMed - indexed for MEDLINE]Related articlesFree article

PYY3-36 injection in mice produces an acute anorexigenic effect followed by a delayed orexigenic effect not observed with other anorexigenic gut hormones.

Parkinson JR, Dhillo WS, Small CJ, Chaudhri OB, Bewick GA, Pritchard I, Moore S, Ghatei MA, Bloom SR.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E698-708. Epub 2008 Feb 19.PMID: 18285527 [PubMed - indexed for MEDLINE]Related articlesFree article

Supraphysiological doses of intravenous PYY3-36 cause nausea, but no additional reduction in food intake.

le Roux CW, Borg CM, Murphy KG, Vincent RP, Ghatei MA, Bloom SR.

Ann Clin Biochem. 2008 Jan;45(Pt 1):93-5.PMID: 18275682 [PubMed - indexed for MEDLINE]Related articles

Can gut hormones control appetite and prevent obesity?

Chaudhri OB, Wynne K, Bloom SR.

Diabetes Care. 2008 Feb;31 Suppl 2:S284-9. Review.PMID: 18227498 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated cocaine- and amphetamine-regulated transcript immunoreactivity in the circulation of patients with neuroendocrine malignancy.

Bech P, Winstanley V, Murphy KG, Sam AH, Meeran K, Ghatei MA, Bloom SR.

J Clin Endocrinol Metab. 2008 Apr;93(4):1246-53. Epub 2008 Jan 22.PMID: 18211969 [PubMed - indexed for MEDLINE]Related articlesFree article

Gut hormones as potential new targets for appetite regulation and the treatment of obesity.

Field BC, Wren AM, Cooke D, Bloom SR.

Drugs. 2008;68(2):147-63. Review.PMID: 18197723 [PubMed - indexed for MEDLINE]Related articles

Biliopancreatic diversion in rats is associated with intestinal hypertrophy and with increased GLP-1, GLP-2 and PYY levels.

Borg CM, le Roux CW, Ghatei MA, Bloom SR, Patel AG.

Obes Surg. 2007 Sep;17(9):1193-8.PMID: 18074494 [PubMed - indexed for MEDLINE]Related articles

Postprandial ghrelin, cholecystokinin, peptide YY, and appetite before and after weight loss in overweight women with and without polycystic ovary syndrome.

Moran LJ, Noakes M, Clifton PM, Wittert GA, Le Roux CW, Ghatei MA, Bloom SR, Norman RJ.

Am J Clin Nutr. 2007 Dec;86(6):1603-10.PMID: 18065576 [PubMed - indexed for MEDLINE]Related articlesFree article

The temporal sequence of gut peptide CNS interactions tracked in vivo by magnetic resonance imaging.

Kuo YT, Parkinson JR, Chaudhri OB, Herlihy AH, So PW, Dhillo WS, Small CJ, Bloom SR, Bell JD.

J Neurosci. 2007 Nov 7;27(45):12341-8.PMID: 17989298 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in thyroid status do not affect plasma peptide YY (PYY) and ghrelin concentrations.

Manuchehri AM, Sathyapalan T, Jayagopal V, Kilpatrick ES, Ghatei MA, Bloom SR, Atkin SL.

Clin Endocrinol (Oxf). 2008 May;68(5):836-8. Epub 2007 Oct 30. No abstract available. PMID: 17973938 [PubMed - indexed for MEDLINE]Related articles

Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass.

le Roux CW, Welbourn R, Werling M, Osborne A, Kokkinos A, Laurenius A, Lönroth H, Fändriks L, Ghatei MA, Bloom SR, Olbers T.

Ann Surg. 2007 Nov;246(5):780-5.PMID: 17968169 [PubMed - indexed for MEDLINE]Related articles

Co-administration of SR141716 with peptide YY3-36 or oxyntomodulin has additive effects on food intake in mice.

White NE, Dhillo WS, Liu YL, Small CJ, Kennett GA, Gardiner JV, Ghatei MA, Bloom SR.

Diabetes Obes Metab. 2008 Feb;10(2):167-70. Epub 2007 Oct 15.PMID: 17941865 [PubMed - indexed for MEDLINE]Related articles

Gastrointestinal satiety signals.

Chaudhri OB, Salem V, Murphy KG, Bloom SR.

Annu Rev Physiol. 2008;70:239-55. Review.PMID: 17937600 [PubMed - indexed for MEDLINE]Related articles

Postprandial ghrelin suppression is exaggerated following major surgery; implications for nutritional recovery.

Nematy M, Brynes AE, Hornick PI, Patterson M, Ghatei MA, Bloom SR, Brett SJ, Frost GS.

Nutr Metab (Lond). 2007 Oct 8;4:20.PMID: 17922905 [PubMed - in process]Related articlesFree article

A family-centered, community-based system of services for children and youth with special health care needs.

Perrin JM, Romm D, Bloom SR, Homer CJ, Kuhlthau KA, Cooley C, Duncan P, Roberts R, Sloyer P, Wells N, Newacheck P.

Arch Pediatr Adolesc Med. 2007 Oct;161(10):933-6. Review.PMID: 17909135 [PubMed - indexed for MEDLINE]Related articlesFree article

Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women.

Dhillo WS, Chaudhri OB, Thompson EL, Murphy KG, Patterson M, Ramachandran R, Nijher GK, Amber V, Kokkinos A, Donaldson M, Ghatei MA, Bloom SR.

J Clin Endocrinol Metab. 2007 Oct;92(10):3958-66. Epub 2007 Jul 17.PMID: 17635940 [PubMed - indexed for MEDLINE]Related articlesFree article