PubMed

Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).

Léger S, Black WC, Deschenes D, Dolman S, Falgueyret JP, Gagnon M, Guiral S, Huang Z, Guay J, Leblanc Y, Li CS, Massé F, Oballa R, Zhang L.

Bioorg Med Chem Lett. . [Epub ahead of print]PMID: 20004097 [PubMed - as supplied by publisher]

Towards a genetic map for Anopheles albimanus: identification of microsatellite markers and a preliminary linkage map for chromosome 2.

Penilla RP, Ranson H, Padilla N, Morgan JC, Steen K, Pignatelli P, Rodríguez AD, Hemingway J, Brogdon WG, Black WC 4th, Benedict MQ.

Am J Trop Med Hyg. 2009 Dec;81(6):1007-12.PMID: 19996429 [PubMed - in process]Related articles

Evidence of multiple chromosomal inversions in Aedes aegypti formosus from Senegal.

Bernhardt SA, Blair C, Sylla M, Bosio C, Black WC 4th.

Insect Mol Biol. 2009 Oct;18(5):557-69.PMID: 19754736 [PubMed - indexed for MEDLINE]Related articles

Epidemiology of Colorado Tick Fever in Montana, Utah, and Wyoming, 1995-2003.

Brackney MM, Marfin AA, Erin Staples J, Stallones L, Keefe T, Black WC, Campbell GL.

Vector Borne Zoonotic Dis. 2009 Sep 2. [Epub ahead of print]PMID: 19725767 [PubMed - as supplied by publisher]Related articles

Aedes aegypti densonucleosis virus amplifies, spreads, and reduces host populations in laboratory cage studies.

Suchman EL, Piper J, De Valdez MW, Kleker B, Neeper L, Plake E, Black WC, Carlson J.

J Med Entomol. 2009 Jul;46(4):909-18.PMID: 19645297 [PubMed - indexed for MEDLINE]Related articles

Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado, New Mexico and Montana.

Black WC 4th, Doty JB, Hughes MT, Beaty BJ, Calisher CH.

Virol J. 2009 Jul 14;6:102.PMID: 19602267 [PubMed - indexed for MEDLINE]Related articlesFree article

Population-based molecular epidemiology of leprosy in Cebu, Philippines.

Sakamuri RM, Kimura M, Li W, Kim HC, Lee H, Kiran MD, Black WC 4th, Balagon M, Gelber R, Cho SN, Brennan PJ, Vissa V.

J Clin Microbiol. 2009 Sep;47(9):2844-54. Epub 2009 Jul 1.PMID: 19571027 [PubMed - indexed for MEDLINE]Related articles

The Neovolcanic Axis Is a Barrier to Gene Flow among Aedes aegypti Populations in Mexico That Differ in Vector Competence for Dengue 2 Virus.

Lozano-Fuentes S, Fernandez-Salas I, de Lourdes Munoz M, Garcia-Rejon J, Olson KE, Beaty BJ, Black WC.

PLoS Negl Trop Dis. 2009 Jun 30;3(6):e468.PMID: 19564909 [PubMed - in process]Related articlesFree article

Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?

Donnelly MJ, Corbel V, Weetman D, Wilding CS, Williamson MS, Black WC 4th.

Trends Parasitol. 2009 May;25(5):213-9.PMID: 19369117 [PubMed - indexed for MEDLINE]Related articles

Gene Flow, Subspecies Composition, and Dengue Virus-2 Susceptibility among Aedes aegypti Collections in Senegal.

Sylla M, Bosio C, Urdaneta-Marquez L, Ndiaye M, Black WC.

PLoS Negl Trop Dis. 2009;3(4):e408. Epub 2009 Apr 14.PMID: 19365540 [PubMed - in process]Related articlesFree article

Patterns of variation in the inhibitor of apoptosis 1 gene of Aedes triseriatus, a transovarial vector of La Crosse virus.

Beck ET, Lozano Fuentes S, Geske DA, Blair CD, Beaty BJ, Black WC 4th.

J Mol Evol. 2009 Apr;68(4):403-13. Epub 2009 Mar 24.PMID: 19308633 [PubMed - indexed for MEDLINE]Related articles

Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors.

Boyd MJ, Crane SN, Robichaud J, Scheigetz J, Black WC, Chauret N, Wang Q, Massé F, Oballa RM.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):675-9. Epub 2008 Dec 24.PMID: 19117756 [PubMed - in process]Related articles

Potential for La Crosse virus segment reassortment in nature.

Reese SM, Blitvich BJ, Blair CD, Geske D, Beaty BJ, Black WC 4th.

Virol J. 2008 Dec 30;5:164.PMID: 19114023 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotyping North American animal Mycobacterium bovis isolates using multilocus variable number tandem repeat analysis.

Martinez LR, Harris B, Black WC 4th, Meyer RM, Brennan PJ, Vissa VD, Jones RL.

J Vet Diagn Invest. 2008 Nov;20(6):707-15.PMID: 18987219 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis.

Robichaud J, Black WC, Thérien M, Paquet J, Oballa RM, Bayly CI, McKay DJ, Wang Q, Isabel E, Léger S, Mellon C, Kimmel DB, Wesolowski G, Percival MD, Massé F, Desmarais S, Falgueyret JP, Crane SN.

J Med Chem. 2008 Oct 23;51(20):6410-20. Epub 2008 Sep 24.PMID: 18811135 [PubMed - indexed for MEDLINE]Related articles

Development and application of a simple colorimetric assay reveals widespread distribution of sodium channel mutations in Thai populations of Aedes aegypti.

Rajatileka S, Black WC 4th, Saavedra-Rodriguez K, Trongtokit Y, Apiwathnasorn C, McCall PJ, Ranson H.

Acta Trop. 2008 Oct;108(1):54-7. Epub 2008 Aug 29.PMID: 18801327 [PubMed - indexed for MEDLINE]Related articles

Comparative genomics of small RNA regulatory pathway components in vector mosquitoes.

Campbell CL, Black WC 4th, Hess AM, Foy BD.

BMC Genomics. 2008 Sep 18;9:425.PMID: 18801182 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegypti.

Saavedra-Rodriguez K, Strode C, Flores Suarez A, Fernandez Salas I, Ranson H, Hemingway J, Black WC 4th.

Genetics. 2008 Oct;180(2):1137-52. Epub 2008 Aug 24.PMID: 18723882 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance to permethrin in Culex tarsalis in northeastern Colorado.

Strong AC, Kondratieff BC, Doyle MS, Black WC 4th.

J Am Mosq Control Assoc. 2008 Jun;24(2):281-8.PMID: 18666537 [PubMed - indexed for MEDLINE]Related articles

A dengue receptor as possible genetic marker of vector competence in Aedes aegypti.

Mercado-Curiel RF, Black WC 4th, Muñoz Mde L.

BMC Microbiol. 2008 Jul 15;8:118.PMID: 18625079 [PubMed - indexed for MEDLINE]Related articlesFree article

The Yin and Yang of linkage disequilibrium: mapping of genes and nucleotides conferring insecticide resistance in insect disease vectors.

Black WC 4th, Gorrochetegui-Escalante N, Randle NP, Donnelly MJ.

Adv Exp Med Biol. 2008;627:71-83. Review.PMID: 18510015 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait loci determining autogeny and body size in the Asian tiger mosquito (Aedes albopictus).

Mori A, Romero-Severson J, Black WC 4th, Severson DW.

Heredity. 2008 Jul;101(1):75-82. Epub 2008 May 7.PMID: 18461085 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic relationships among Aedes aegypti collections in Venezuela as determined by mitochondrial DNA variation and nuclear single nucleotide polymorphisms.

Urdaneta-Marquez L, Bosio C, Herrera F, Rubio-Palis Y, Salasek M, Black WC 4th.

Am J Trop Med Hyg. 2008 Mar;78(3):479-91.PMID: 18337347 [PubMed - indexed for MEDLINE]Related articlesFree article

Methodology and application of prospective reader studies: self-assessment module.

Krupinski EA, Black WC, Chew FS.

AJR Am J Roentgenol. 2008 Mar;190(3 Suppl):S29-34.PMID: 18321846 [PubMed - indexed for MEDLINE]Related articlesFree article

Methodology and application of clinical trials in radiology: self-assessment module.

Black WC, Krupinski EA, Relyea-Chew A, Chew FS.

AJR Am J Roentgenol. 2008 Mar;190(3 Suppl):S23-8.PMID: 18321845 [PubMed - indexed for MEDLINE]Related articlesFree article

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

Gauthier JY, Chauret N, Cromlish W, Desmarais S, Duong le T, Falgueyret JP, Kimmel DB, Lamontagne S, Léger S, LeRiche T, Li CS, Massé F, McKay DJ, Nicoll-Griffith DA, Oballa RM, Palmer JT, Percival MD, Riendeau D, Robichaud J, Rodan GA, Rodan SB, Seto C, Thérien M, Truong VL, Venuti MC, Wesolowski G, Young RN, Zamboni R, Black WC.

Bioorg Med Chem Lett. 2008 Feb 1;18(3):923-8. Epub 2008 Jan 15.PMID: 18226527 [PubMed - indexed for MEDLINE]Related articles

A mutation in the voltage-gated sodium channel gene associated with pyrethroid resistance in Latin American Aedes aegypti.

Saavedra-Rodriguez K, Urdaneta-Marquez L, Rajatileka S, Moulton M, Flores AE, Fernandez-Salas I, Bisset J, Rodriguez M, McCall PJ, Donnelly MJ, Ranson H, Hemingway J, Black WC 4th.

Insect Mol Biol. 2007 Dec;16(6):785-98.PMID: 18093007 [PubMed - indexed for MEDLINE]Related articles

Genomic analysis of detoxification genes in the mosquito Aedes aegypti.

Strode C, Wondji CS, David JP, Hawkes NJ, Lumjuan N, Nelson DR, Drane DR, Karunaratne SH, Hemingway J, Black WC 4th, Ranson H.

Insect Biochem Mol Biol. 2008 Jan;38(1):113-23. Epub 2007 Sep 29.PMID: 18070670 [PubMed - indexed for MEDLINE]Related articles

Computed tomography screening for lung cancer: review of screening principles and update on current status.

Black WC.

Cancer. 2007 Dec 1;110(11):2370-84. Review.PMID: 17941031 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of cathepsin k inhibitor basicity on in vivo off-target activities.

Desmarais S, Black WC, Oballa R, Lamontagne S, Riendeau D, Tawa P, Duong le T, Pickarski M, Percival MD.

Mol Pharmacol. 2008 Jan;73(1):147-56. Epub 2007 Oct 16.PMID: 17940194 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternative splicing generates multiple transcripts of the inhibitor of apoptosis protein 1 in Aedes and Culex spp. mosquitoes.

Beck ET, Blair CD, Black WC 4th, Beaty BJ, Blitvich BJ.

Insect Biochem Mol Biol. 2007 Nov;37(11):1222-33. Epub 2007 Aug 7.PMID: 17916508 [PubMed - indexed for MEDLINE]Related articlesFree article

The identification of potent, selective, and bioavailable cathepsin S inhibitors.

Gauthier JY, Black WC, Courchesne I, Cromlish W, Desmarais S, Houle R, Lamontagne S, Li CS, Massé F, McKay DJ, Ouellet M, Robichaud J, Truchon JF, Truong VL, Wang Q, Percival MD.

Bioorg Med Chem Lett. 2007 Sep 1;17(17):4929-33. Epub 2007 Jun 10.PMID: 17590332 [PubMed - indexed for MEDLINE]Related articles

Primary amides as selective inhibitors of cathepsin K.

Léger S, Bayly CI, Black WC, Desmarais S, Falgueyret JP, Massé F, Percival MD, Truchon JF.

Bioorg Med Chem Lett. 2007 Aug 1;17(15):4328-32. Epub 2007 May 16.PMID: 17544269 [PubMed - indexed for MEDLINE]Related articles

Affordable assays for genotyping single nucleotide polymorphisms in insects.

Black WC 4th, Vontas JG.

Insect Mol Biol. 2007 Aug;16(4):377-87. Epub 2007 May 4. Review.PMID: 17488301 [PubMed - indexed for MEDLINE]Related articles

Screening coronary CT angiography: no time soon.

Black WC, Czum JM.

J Am Coll Radiol. 2007 May;4(5):295-9. Review. No abstract available. PMID: 17467611 [PubMed - indexed for MEDLINE]Related articles

Large field trial for lung cancer screening: putting the wrong cart before the horse?

Black WC, Aberle DR, Berg CD.

Radiology. 2007 May;243(2):314-6; discussion 317-8. No abstract available. PMID: 17456862 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological study.

Weng X, Wang Z, Liu J, Kimura M, Black WC 4th, Brennan PJ, Li H, Vissa VD.

J Clin Microbiol. 2007 Jun;45(6):1728-34. Epub 2007 Apr 11.PMID: 17428944 [PubMed - indexed for MEDLINE]Related articlesFree article

The appropriateness of employing imaging screening technologies: report of the methods committee of the ACR task force on screening technologies.

Hillman BJ, Black WC, D'orsi C, Hauser JB, Smith R.

J Am Coll Radiol. 2004 Nov;1(11):861-4. Review.PMID: 17411718 [PubMed - indexed for MEDLINE]Related articles

Beta-substituted cyclohexanecarboxamide cathepsin K inhibitors: modification of the 1,2-disubstituted aromatic core.

Robichaud J, Bayly CI, Black WC, Desmarais S, Léger S, Massé F, McKay DJ, Oballa RM, Pâquet J, Percival MD, Truchon JF, Wesolowski G, Crane SN.

Bioorg Med Chem Lett. 2007 Jun 1;17(11):3146-51. Epub 2007 Mar 15.PMID: 17408953 [PubMed - indexed for MEDLINE]Related articles

CT screening for lung cancer: spiraling into confusion?

Black WC, Baron JA.

JAMA. 2007 Mar 7;297(9):995-7. No abstract available. PMID: 17341714 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of insecticide resistance in field populations of Aedes aegypti (L.) from Quintana Roo, Southern Mexico.

Flores AE, Grajales JS, Salas IF, Garcia GP, Becerra MH, Lozano S, Brogdon WG, Black WC 4th, Beaty B.

J Am Mosq Control Assoc. 2006 Dec;22(4):672-7.PMID: 17304936 [PubMed - indexed for MEDLINE]Related articles

Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus.

Wondji CS, Morgan J, Coetzee M, Hunt RH, Steen K, Black WC 4th, Hemingway J, Ranson H.

BMC Genomics. 2007 Jan 29;8:34.PMID: 17261170 [PubMed - indexed for MEDLINE]Related articlesFree article

Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones.

Isabel E, Aspiotis R, Black WC, Colucci J, Fortin R, Giroux A, Grimm EL, Han Y, Mellon C, Nicholson DW, Rasper DM, Renaud J, Roy S, Tam J, Tawa P, Vaillancourt JP, Xanthoudakis S, Zamboni RJ.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1671-4. Epub 2007 Jan 11.PMID: 17251019 [PubMed - indexed for MEDLINE]Related articles

Phylogeny of parasitiform mites (Acari) based on rRNA.

Klompen H, Lekveishvili M, Black WC 4th.

Mol Phylogenet Evol. 2007 Jun;43(3):936-51. Epub 2006 Nov 6.PMID: 17197202 [PubMed - indexed for MEDLINE]Related articles

Spatial population genetic structure and limited dispersal in a Rocky Mountain alpine stream insect.

Finn DS, Theobald DM, Black WC 4th, Poff NL.

Mol Ecol. 2006 Oct;15(12):3553-66.PMID: 17032257 [PubMed - indexed for MEDLINE]Related articles

The consequences of lysosomotropism on the design of selective cathepsin K inhibitors.

Black WC, Percival MD.

Chembiochem. 2006 Oct;7(10):1525-35. Review.PMID: 16921579 [PubMed - indexed for MEDLINE]Related articles

Randomized clinical trials for cancer screening: rationale and design considerations for imaging tests.

Black WC.

J Clin Oncol. 2006 Jul 10;24(20):3252-60. Review.PMID: 16829649 [PubMed - indexed for MEDLINE]Related articles

Dengue virus circulation and evolution in Mexico: a phylogenetic perspective.

Díaz FJ, Black WC 4th, Farfán-Ale JA, Loroño-Pino MA, Olson KE, Beaty BJ.

Arch Med Res. 2006 Aug;37(6):760-73.PMID: 16824937 [PubMed - indexed for MEDLINE]Related articles

Molecular evidence for trypanosomatids in Culex mosquitoes collected during a West Nile virus survey.

Van Dyken M, Bolling BG, Moore CG, Blair CD, Beaty BJ, Black WC 4th, Foy BD.

Int J Parasitol. 2006 Aug;36(9):1015-23. Epub 2006 Jun 2.PMID: 16782103 [PubMed - indexed for MEDLINE]Related articles

Heated oligonucleotide ligation assay (HOLA): an affordable single nucleotide polymorphism assay.

Black WC 4th, Gorrochotegui-Escalante N, Duteau NM.

J Med Entomol. 2006 Mar;43(2):238-47.PMID: 16619605 [PubMed - indexed for MEDLINE]Related articles