PubMed

Association of Polymorphism in the Receptor for Advanced Glycation End Products (RAGE) Gene with Circulating RAGE Levels.

Gaens KH, Ferreira I, van der Kallen CJ, van Greevenbroek MM, Blaak EE, Feskens EJ, Dekker JM, Nijpels G, Heine RJ, 't Hart LM, de Groot PG, Stehouwer CD, Schalkwijk CG.

J Clin Endocrinol Metab. 2009 Nov 4. [Epub ahead of print]PMID: 19890027 [PubMed - as supplied by publisher]Related articles

Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study.

Corpeleijn E, Petersen L, Holst C, Saris WH, Astrup A, Langin D, Macdonald I, Martinez JA, Oppert JM, Polak J, Pedersen O, Froguel P, Arner P, Sørensen TI, Blaak EE.

Obesity (Silver Spring). 2009 Oct 29. [Epub ahead of print]PMID: 19876004 [PubMed - as supplied by publisher]Related articles

Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use.

van Can JG, Ijzerman TH, van Loon LJ, Brouns F, Blaak EE.

Br J Nutr. 2009 Nov;102(10):1408-13. Epub 2009 Aug 11.PMID: 19671200 [PubMed - in process]Related articles

Reduced glycaemic and insulinaemic responses following trehalose ingestion: implications for postprandial substrate use.

van Can JG, Ijzerman TH, van Loon LJ, Brouns F, Blaak EE.

Br J Nutr. 2009 Nov;102(10):1395-9. Epub 2009 Aug 7.PMID: 19664296 [PubMed - in process]Related articles

Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies.

Engelen L, Ferreira I, Brouwers O, Henry RM, Dekker JM, Nijpels G, Heine RJ, van Greevenbroek MM, van der Kallen CJ, Blaak EE, Feskens EJ, ten Cate H, Stehouwer CD, Schalkwijk CG.

J Hypertens. 2009 Jul;27(7):1399-403.PMID: 19412133 [PubMed - indexed for MEDLINE]Related articles

Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study.

Goossens GH, Petersen L, Blaak EE, Hul G, Arner P, Astrup A, Froguel P, Patel K, Pedersen O, Polak J, Oppert JM, Martinez JA, Sørensen TI, Saris WH; NUGENOB Consortium.

Int J Obes (Lond). 2009 Jun;33(6):669-79. Epub 2009 Apr 28.PMID: 19399022 [PubMed - in process]Related articles

Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study.

Jacobs M, van Greevenbroek MM, van der Kallen CJ, Ferreira I, Blaak EE, Feskens EJ, Jansen EH, Schalkwijk CG, Stehouwer CD.

Eur J Clin Invest. 2009 Jun;39(6):437-44. Epub 2009 Apr 9.PMID: 19397692 [PubMed - in process]Related articles

Lifestyle intervention for prevention of diabetes: determinants of success for future implementation.

Roumen C, Blaak EE, Corpeleijn E.

Nutr Rev. 2009 Mar;67(3):132-46. Review.PMID: 19239628 [PubMed - indexed for MEDLINE]Related articles

Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyle.

Corpeleijn E, Saris WH, Blaak EE.

Obes Rev. 2009 Mar;10(2):178-93. Epub 2009 Jan 15. Review.PMID: 19207879 [PubMed - indexed for MEDLINE]Related articles

Changes in transferrin are related to changes in insulin resistance: the SLIM study.

Roumen C, Feskens EJ, Jansen EH, Saris WH, Blaak EE.

Diabet Med. 2008 Dec;25(12):1478-82.PMID: 19046249 [PubMed - indexed for MEDLINE]Related articles

Fasting and postprandial remnant-like particle cholesterol concentrations in obese participants are associated with plasma triglycerides, insulin resistance, and body fat distribution.

van Hees AM, Saris WH, Dallinga-Thie GM, Hul GB, Martinez JA, Oppert JM, Stich V, Astrup A, Arner P, Sørensen TI, Blaak EE.

J Nutr. 2008 Dec;138(12):2399-405.PMID: 19022964 [PubMed - indexed for MEDLINE]Related articles

Obesity and the lung: 5. Obesity and COPD.

Franssen FM, O'Donnell DE, Goossens GH, Blaak EE, Schols AM.

Thorax. 2008 Dec;63(12):1110-7. Review.PMID: 19020276 [PubMed - indexed for MEDLINE]Related articles

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients.

Boon H, Bosselaar M, Praet SF, Blaak EE, Saris WH, Wagenmakers AJ, McGee SL, Tack CJ, Smits P, Hargreaves M, van Loon LJ.

Diabetologia. 2008 Oct;51(10):1893-900. Epub 2008 Aug 16.PMID: 18709353 [PubMed - indexed for MEDLINE]Related articles

LIPGENE food-exchange model for alteration of dietary fat quantity and quality in free-living participants from eight European countries.

Shaw DI, Tierney AC, McCarthy S, Upritchard J, Vermunt S, Gulseth HL, Drevon CA, Blaak EE, Saris WH, Karlström B, Helal O, Defoort C, Gallego R, López-Miranda J, Siedlecka D, Malczewska-Malec M, Roche HM, Lovegrove JA.

Br J Nutr. 2009 Mar;101(5):750-9. Epub 2008 Aug 5.PMID: 18680629 [PubMed - in process]Related articles

Adipose tissue fatty acid metabolism in insulin-resistant men.

Bickerton AS, Roberts R, Fielding BA, Tornqvist H, Blaak EE, Wagenmakers AJ, Gilbert M, Humphreys SM, Karpe F, Frayn KN.

Diabetologia. 2008 Aug;51(8):1466-74. Epub 2008 May 27. Erratum in: Diabetologia. 2008 Oct;51(10):1936. PMID: 18504545 [PubMed - indexed for MEDLINE]Related articles

Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians.

Meex SJ, van Vliet-Ostaptchouk JV, van der Kallen CJ, van Greevenbroek MM, Schalkwijk CG, Feskens EJ, Blaak EE, Wijmenga C, Hofker MH, Stehouwer CD, de Bruin TW.

Mol Genet Metab. 2008 Jul;94(3):352-5. Epub 2008 Apr 28.PMID: 18445538 [PubMed - indexed for MEDLINE]Related articles

Impact of 3-year lifestyle intervention on postprandial glucose metabolism: the SLIM study.

Roumen C, Corpeleijn E, Feskens EJ, Mensink M, Saris WH, Blaak EE.

Diabet Med. 2008 May;25(5):597-605.PMID: 18445174 [PubMed - indexed for MEDLINE]Related articles

Insulin acutely upregulates protein expression of the fatty acid transporter CD36 in human skeletal muscle in vivo.

Corpeleijn E, Pelsers MM, Soenen S, Mensink M, Bouwman FG, Kooi ME, Saris WH, Glatz JF, Blaak EE.

J Physiol Pharmacol. 2008 Mar;59(1):77-83.PMID: 18441389 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term beta-adrenergic regulation of leptin, adiponectin and interleukin-6 secretion in vivo in lean and obese subjects.

Goossens GH, Jocken JW, van Baak MA, Jansen EH, Saris WH, Blaak EE.

Diabetes Obes Metab. 2008 Nov;10(11):1029-38. Epub 2008 Apr 22.PMID: 18435774 [PubMed - indexed for MEDLINE]Related articles

Reduced oxidation of dietary fat after a short term high-carbohydrate diet.

Roberts R, Bickerton AS, Fielding BA, Blaak EE, Wagenmakers AJ, Chong MF, Gilbert M, Karpe F, Frayn KN.

Am J Clin Nutr. 2008 Apr;87(4):824-31.PMID: 18400703 [PubMed - indexed for MEDLINE]Related articlesFree article

Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.

Jocken JW, Roepstorff C, Goossens GH, van der Baan P, van Baak M, Saris WH, Kiens B, Blaak EE.

Diabetes. 2008 Jul;57(7):1834-41. Epub 2008 Apr 8.PMID: 18398140 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population.

Du H, van der A DL, van Bakel MM, van der Kallen CJ, Blaak EE, van Greevenbroek MM, Jansen EH, Nijpels G, Stehouwer CD, Dekker JM, Feskens EJ.

Am J Clin Nutr. 2008 Mar;87(3):655-61.PMID: 18326604 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired skeletal muscle substrate oxidation in glucose-intolerant men improves after weight loss.

Corpeleijn E, Mensink M, Kooi ME, Roekaerts PM, Saris WH, Blaak EE.

Obesity (Silver Spring). 2008 May;16(5):1025-32. Epub 2008 Feb 28.PMID: 18309299 [PubMed - indexed for MEDLINE]Related articles

Catecholamine-induced lipolysis in adipose tissue and skeletal muscle in obesity.

Jocken JW, Blaak EE.

Physiol Behav. 2008 May 23;94(2):219-30. Epub 2008 Jan 11. Review.PMID: 18262211 [PubMed - indexed for MEDLINE]Related articles

Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene.

Jocken JW, Blaak EE, van der Kallen CJ, van Baak MA, Saris WH.

Metabolism. 2008 Mar;57(3):326-32.PMID: 18249203 [PubMed - indexed for MEDLINE]Related articles

Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific.

Jocken JW, Smit E, Goossens GH, Essers YP, van Baak MA, Mensink M, Saris WH, Blaak EE.

Histochem Cell Biol. 2008 Apr;129(4):535-8. Epub 2008 Jan 26.PMID: 18224330 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men.

Jocken JW, Goossens GH, van Hees AM, Frayn KN, van Baak M, Stegen J, Pakbiers MT, Saris WH, Blaak EE.

Diabetologia. 2008 Feb;51(2):320-7. Epub 2007 Dec 5.PMID: 18060661 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate source use in older, trained males after decades of endurance training.

Boon H, Jonkers RA, Koopman R, Blaak EE, Saris WH, Wagenmakers AJ, VAN Loon LJ.

Med Sci Sports Exerc. 2007 Dec;39(12):2160-70.PMID: 18046187 [PubMed - indexed for MEDLINE]Related articles

The effects of hydralazine on lipolysis in subcutaneous adipose tissue in humans.

Boon N, Goossens GH, Blaak EE, Saris WH.

Metabolism. 2007 Dec;56(12):1742-8.PMID: 17998030 [PubMed - indexed for MEDLINE]Related articles

Lifestyle intervention and adipokine levels in subjects at high risk for type 2 diabetes: the Study on Lifestyle intervention and Impaired glucose tolerance Maastricht (SLIM).

Corpeleijn E, Feskens EJ, Jansen EH, Mensink M, Saris WH, Blaak EE.

Diabetes Care. 2007 Dec;30(12):3125-7. Epub 2007 Sep 21.PMID: 17890316 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle uncoupling protein-3 restores upon intervention in the prediabetic and diabetic state: implications for diabetes pathogenesis?

Mensink M, Hesselink MK, Borghouts LB, Keizer H, Moonen-Kornips E, Schaart G, Blaak EE, Schrauwen P.

Diabetes Obes Metab. 2007 Jul;9(4):594-6.PMID: 17587402 [PubMed - indexed for MEDLINE]Related articles

Impaired fat-induced thermogenesis in obese subjects: the NUGENOB study.

Blaak EE, Hul G, Verdich C, Stich V, Martinez JA, Petersen M, Feskens EF, Patel K, Oppert JM, Barbe P, Toubro S, Polak J, Anderson I, Astrup A, Macdonald I, Langin D, Sørensen T, Saris WH; NUGENOB Consortium.

Obesity (Silver Spring). 2007 Mar;15(3):653-63.PMID: 17372316 [PubMed - indexed for MEDLINE]Related articles

Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state.

Jocken JW, Langin D, Smit E, Saris WH, Valle C, Hul GB, Holm C, Arner P, Blaak EE.

J Clin Endocrinol Metab. 2007 Jun;92(6):2292-9. Epub 2007 Mar 13.PMID: 17356053 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocrine role of the renin-angiotensin system in human adipose tissue and muscle: effect of beta-adrenergic stimulation.

Goossens GH, Jocken JW, Blaak EE, Schiffers PM, Saris WH, van Baak MA.

Hypertension. 2007 Mar;49(3):542-7. Epub 2007 Jan 15.PMID: 17224474 [PubMed - indexed for MEDLINE]Related articlesFree article

Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period.

Bickerton AS, Roberts R, Fielding BA, Hodson L, Blaak EE, Wagenmakers AJ, Gilbert M, Karpe F, Frayn KN.

Diabetes. 2007 Jan;56(1):168-76.PMID: 17192479 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery.

Boon H, Blaak EE, Saris WH, Keizer HA, Wagenmakers AJ, van Loon LJ.

Diabetologia. 2007 Jan;50(1):103-12. Epub 2006 Nov 28.PMID: 17131144 [PubMed - indexed for MEDLINE]Related articles

Association of a beta-2 adrenoceptor (ADRB2) gene variant with a blunted in vivo lipolysis and fat oxidation.

Jocken JW, Blaak EE, Schiffelers S, Arner P, van Baak MA, Saris WH.

Int J Obes (Lond). 2007 May;31(5):813-9. Epub 2006 Nov 28.PMID: 17130852 [PubMed - indexed for MEDLINE]Related articles

Genotype-by-nutrient interactions assessed in European obese women. A case-only study.

Santos JL, Boutin P, Verdich C, Holst C, Larsen LH, Toubro S, Dina C, Saris WH, Blaak EE, Hoffstedt J, Taylor MA, Polak J, Clement K, Langin D, Astrup A, Froguel P, Pedersen O, Sorensen TI, Martinez JA; NUGENOB* consortium.

Eur J Nutr. 2006 Dec;45(8):454-62. Epub 2006 Nov 1.PMID: 17080261 [PubMed - indexed for MEDLINE]Related articles

Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects.

Goossens GH, Blaak EE, Schiffers PM, Saris WH, van Baak MA.

Diabetologia. 2006 Dec;49(12):3009-16. Epub 2006 Sep 26.PMID: 17019594 [PubMed - indexed for MEDLINE]Related articles

Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance.

Corpeleijn E, van der Kallen CJ, Kruijshoop M, Magagnin MG, de Bruin TW, Feskens EJ, Saris WH, Blaak EE.

Diabet Med. 2006 Aug;23(8):907-11.PMID: 16911630 [PubMed - indexed for MEDLINE]Related articles

Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities: the SLIM study.

Corpeleijn E, Feskens EJ, Jansen EH, Mensink M, Saris WH, de Bruin TW, Blaak EE.

Diabetologia. 2006 Oct;49(10):2392-401. Epub 2006 Aug 3.PMID: 16896932 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II: a hormone that affects lipid metabolism in adipose tissue.

Goossens GH, Blaak EE, Arner P, Saris WH, van Baak MA.

Int J Obes (Lond). 2007 Feb;31(2):382-4. Epub 2006 May 16.PMID: 16703000 [PubMed - indexed for MEDLINE]Related articles

Fat oxidation before and after a high fat load in the obese insulin-resistant state.

Blaak EE, Hul G, Verdich C, Stich V, Martinez A, Petersen M, Feskens EF, Patel K, Oppert JM, Barbe P, Toubro S, Anderson I, Polak J, Astrup A, Macdonald IA, Langin D, Holst C, Sørensen TI, Saris WH.

J Clin Endocrinol Metab. 2006 Apr;91(4):1462-9. Epub 2006 Jan 31.PMID: 16449343 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.

Goossens GH, McQuaid SE, Dennis AL, van Baak MA, Blaak EE, Frayn KN, Saris WH, Karpe F.

J Physiol. 2006 Mar 1;571(Pt 2):451-60. Epub 2006 Jan 5.PMID: 16396927 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment.

Schrauwen P, Mensink M, Schaart G, Moonen-Kornips E, Sels JP, Blaak EE, Russell AP, Hesselink MK.

J Clin Endocrinol Metab. 2006 Apr;91(4):1520-5. Epub 2005 Dec 29.PMID: 16384852 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic fluxes in skeletal muscle in relation to obesity and insulin resistance.

Blaak EE.

Best Pract Res Clin Endocrinol Metab. 2005 Sep;19(3):391-403. Review.PMID: 16150382 [PubMed - indexed for MEDLINE]Related articles

Lifestyle intervention and fatty acid metabolism in glucose-intolerant subjects.

Mensink M, Blaak EE, Wagenmakers AJ, Saris WH.

Obes Res. 2005 Aug;13(8):1354-62.PMID: 16129717 [PubMed - indexed for MEDLINE]Related articles

Postprandial interleukin-6 release from skeletal muscle in men with impaired glucose tolerance can be reduced by weight loss.

Corpeleijn E, Saris WH, Jansen EH, Roekaerts PM, Feskens EJ, Blaak EE.

J Clin Endocrinol Metab. 2005 Oct;90(10):5819-24. Epub 2005 Jul 19.PMID: 16030153 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired beta-adrenergically mediated lipolysis in skeletal muscle of obese subjects.

Blaak EE, Schiffelers SL, Saris WH, Mensink M, Kooi ME.

Diabetologia. 2004 Aug;47(8):1462-8. Epub 2004 Jul 28.PMID: 15309296 [PubMed - indexed for MEDLINE]Related articles

Basic disturbances in skeletal muscle fatty acid metabolism in obesity and type 2 diabetes mellitus.

Blaak EE.

Proc Nutr Soc. 2004 May;63(2):323-30. Review.PMID: 15294050 [PubMed - indexed for MEDLINE]Related articles