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The distinction of metabolically 'healthy' from 'unhealthy' obese individuals.

Blüher M.

Curr Opin Lipidol. 2009 Nov 12. [Epub ahead of print]PMID: 19915462 [PubMed - as supplied by publisher]Related articles

Effect of Genetic Variation in the Human Fatty Acid Synthase Gene (FASN) on Obesity and Fat Depot-Specific mRNA Expression.

Schleinitz D, Klöting N, Körner A, Berndt J, Reichenbächer M, Tönjes A, Ruschke K, Böttcher Y, Dietrich K, Enigk B, Filz M, Schön MR, Jenkner J, Kiess W, Stumvoll M, Blüher M, Kovacs P.

Obesity (Silver Spring). 2009 Oct 29. [Epub ahead of print]PMID: 19876008 [PubMed - as supplied by publisher]Related articles

Amyloid precursor protein expression is induced by tumor necrosis factor alpha in 3T3-L1 adipocytes.

Sommer G, Kralisch S, Lipfert J, Weise S, Krause K, Jessnitzer B, Lössner U, Blüher M, Stumvoll M, Fasshauer M.

J Cell Biochem. 2009 Oct 27. [Epub ahead of print]PMID: 19862700 [PubMed - as supplied by publisher]Related articles

Serum levels of the adipokine chemerin in relation to renal function.

Pfau D, Bachmann A, Lössner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.

Diabetes Care. 2009 Oct 16. [Epub ahead of print]PMID: 19837789 [PubMed - as supplied by publisher]Related articles

Complement Factor H is expressed in adipose tissue in association with insulin resistance.

Moreno-Navarrete JM, Martínez-Barricarte R, Catalán V, Sabater M, Gómez-Ambrosi J, Ortega FJ, Ricart W, Blüher M, Frühbeck G, de Cordoba SR, Fernández-Real MJ.

Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833879 [PubMed - as supplied by publisher]Related articles

Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease.

Sixt S, Beer S, Blüher M, Korff N, Peschel T, Sonnabend M, Teupser D, Thiery J, Adams V, Schuler G, Niebauer J.

Eur Heart J. 2009 Sep 30. [Epub ahead of print]PMID: 19793768 [PubMed - as supplied by publisher]Related articles

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.

Tönjes A, Koriath M, Schleinitz D, Dietrich K, Böttcher Y, Rayner NW, Almgren P, Enigk B, Richter O, Rohm S, Fischer-Rosinsky A, Pfeiffer A, Hoffmann K, Krohn K, Aust G, Spranger J, Groop L, Blüher M, Kovacs P, Stumvoll M.

Hum Mol Genet. 2009 Dec 1;18(23):4662-8. Epub 2009 Sep 3.PMID: 19729412 [PubMed - in process]Related articlesFree article

Serum fibroblast growth factor 21 levels in gestational diabetes mellitus in relation to insulin resistance and dyslipidemia.

Stein S, Stepan H, Kratzsch J, Verlohren M, Verlohren HJ, Drynda K, Lössner U, Blüher M, Stumvoll M, Fasshauer M.

Metabolism. 2009 Aug 20. [Epub ahead of print]PMID: 19699495 [PubMed - as supplied by publisher]Related articles

Lack of Significant Effects of the Type 2 Diabetes Susceptibility Loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on Diabetes and Quantitative Metabolic Traits.

Schleinitz D, Tönjes A, Böttcher Y, Dietrich K, Enigk B, Koriath M, Scholz GH, Blüher M, Zeggini E, McCarthy MI, Kovacs P, Stumvoll M.

Horm Metab Res. 2009 Aug 10. [Epub ahead of print]PMID: 19670153 [PubMed - as supplied by publisher]Related articles

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL.

Scherneck S, Nestler M, Vogel H, Blüher M, Block MD, Berriel Diaz M, Herzig S, Schulz N, Teichert M, Tischer S, Al-Hasani H, Kluge R, Schürmann A, Joost HG.

PLoS Genet. 2009 Jul;5(7):e1000541. Epub 2009 Jul 3.PMID: 19578398 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.

Böttcher Y, Unbehauen H, Klöting N, Ruschke K, Körner A, Schleinitz D, Tönjes A, Enigk B, Wolf S, Dietrich K, Koriath M, Scholz GH, Tseng YH, Dietrich A, Schön MR, Kiess W, Stumvoll M, Blüher M, Kovacs P.

Diabetes. 2009 Sep;58(9):2119-28. Epub 2009 Jun 5.PMID: 19502417 [PubMed - indexed for MEDLINE]Related articles

Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice.

Ruschke K, Ebelt H, Klöting N, Boettger T, Raum K, Blüher M, Braun T.

PLoS One. 2009;4(5):e5516. Epub 2009 May 13.PMID: 19436734 [PubMed - indexed for MEDLINE]Related articlesFree article

Antioxidants prevent health-promoting effects of physical exercise in humans.

Ristow M, Zarse K, Oberbach A, Klöting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Blüher M.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8665-70. Epub 2009 May 11.PMID: 19433800 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue dysfunction in obesity.

Blüher M.

Exp Clin Endocrinol Diabetes. 2009 Jun;117(6):241-50. Epub 2009 Apr 8. Review.PMID: 19358089 [PubMed - indexed for MEDLINE]Related articles

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity.

Blüher M, Bashan N, Shai I, Harman-Boehm I, Tarnovscki T, Avinaoch E, Stumvoll M, Dietrich A, Klöting N, Rudich A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2507-15. Epub 2009 Apr 7.PMID: 19351724 [PubMed - indexed for MEDLINE]Related articles

Serum levels of angiopoietin-related growth factor in diabetes mellitus and chronic hemodialysis.

Ebert T, Bachmann A, Lössner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.

Metabolism. 2009 Apr;58(4):547-51.PMID: 19303977 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1beta is a positive regulator of TIARP/STAMP2 gene and protein expression in adipocytes in vitro.

Kralisch S, Sommer G, Weise S, Lipfert J, Lossner U, Kamprad M, Schröck K, Bluher M, Stumvoll M, Fasshauer M.

FEBS Lett. 2009 Apr 2;583(7):1196-200. Epub 2009 Mar 14.PMID: 19289123 [PubMed - indexed for MEDLINE]Related articles

Percutaneous intragastric catheter (PIC) for administration of an unpalatable substance to large animals.

Oleszczuk A, Spannbauer MM, Bluher M, Ott R, Pietsch UC, Schneider K, Madaj-Sterba P, Furll M, Hauss JP, Schön MR.

J Invest Surg. 2009 Mar-Apr;22(2):122-8.PMID: 19283615 [PubMed - indexed for MEDLINE]Related articles

MicroRNA expression in human omental and subcutaneous adipose tissue.

Klöting N, Berthold S, Kovacs P, Schön MR, Fasshauer M, Ruschke K, Stumvoll M, Blüher M.

PLoS One. 2009;4(3):e4699. Epub 2009 Mar 4.PMID: 19259271 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1beta induces the novel adipokine chemerin in adipocytes in vitro.

Kralisch S, Weise S, Sommer G, Lipfert J, Lossner U, Bluher M, Stumvoll M, Fasshauer M.

Regul Pept. 2009 Apr 10;154(1-3):102-6. Epub 2009 Feb 20.PMID: 19233230 [PubMed - indexed for MEDLINE]Related articles

Preliminary report: Serum levels of retinol-binding protein 4 in preeclampsia.

Stepan H, Ebert T, Schrey S, Reisenbüchler C, Blüher M, Stumvoll M, Kratzsch J, Tönnessen P, Faber R, Fasshauer M.

Metabolism. 2009 Mar;58(3):275-7.PMID: 19217438 [PubMed - indexed for MEDLINE]Related articles

Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells.

Sommer G, Kralisch S, Stangl V, Vietzke A, Köhler U, Stepan H, Faber R, Schubert A, Lössner U, Bluher M, Stumvoll M, Fasshauer M.

J Cell Biochem. 2009 Mar 1;106(4):729-37.PMID: 19173302 [PubMed - indexed for MEDLINE]Related articles

Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.

Linke A, Sonnabend M, Fasshauer M, Höllriegel R, Schuler G, Niebauer J, Stumvoll M, Blüher M.

Atherosclerosis. 2009 Jul;205(1):207-13. Epub 2008 Dec 3.PMID: 19131065 [PubMed - indexed for MEDLINE]Related articles

Serum levels of angiopoietin-related growth factor are increased in preeclampsia.

Stepan H, Ebert T, Schrey S, Reisenbüchler C, Stein S, Lossner U, Bluher M, Stumvoll M, Kratzsch J, Faber R, Fasshauer M.

Am J Hypertens. 2009 Mar;22(3):314-8. Epub 2008 Dec 4.PMID: 19057519 [PubMed - indexed for MEDLINE]Related articles

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue.

Youn BS, Bang SI, Klöting N, Park JW, Lee N, Oh JE, Pi KB, Lee TH, Ruschke K, Fasshauer M, Stumvoll M, Blüher M.

Diabetes. 2009 Mar;58(3):627-36. Epub 2008 Dec 3.PMID: 19056610 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.

Fischer-Rosinsky A, Fisher E, Kovacs P, Blüher M, Möhlig M, Pfeiffer AF, Boeing H, Spranger J.

PLoS One. 2008;3(12):e3852. Epub 2008 Dec 4.PMID: 19052638 [PubMed - indexed for MEDLINE]Related articlesFree article

Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine.

Sommer G, Garten A, Petzold S, Beck-Sickinger AG, Blüher M, Stumvoll M, Fasshauer M.

Clin Sci (Lond). 2008 Jul;115(1):13-23. Review.PMID: 19016657 [PubMed - indexed for MEDLINE]Related articles

Lipocalin-2 is induced by interleukin-1beta in murine adipocytes in vitro.

Sommer G, Weise S, Kralisch S, Lossner U, Bluher M, Stumvoll M, Fasshauer M.

J Cell Biochem. 2009 Jan 1;106(1):103-8.PMID: 19009554 [PubMed - indexed for MEDLINE]Related articles

Serum levels of adipocyte fatty acid binding protein are increased in gestational diabetes mellitus.

Kralisch S, Stepan H, Kratzsch J, Verlohren M, Verlohren HJ, Drynda K, Lössner U, Blüher M, Stumvoll M, Fasshauer M.

Eur J Endocrinol. 2009 Jan;160(1):33-8. Epub 2008 Oct 10.PMID: 18849305 [PubMed - indexed for MEDLINE]Related articles

Vaspin serum concentrations in patients with carotid stenosis.

Aust G, Richter O, Rohm S, Kerner C, Hauss J, Klöting N, Ruschke K, Kovacs P, Youn BS, Blüher M.

Atherosclerosis. 2009 May;204(1):262-6. Epub 2008 Sep 2.PMID: 18848328 [PubMed - indexed for MEDLINE]Related articles

Serum levels of the adipokine FGF21 depend on renal function.

Stein S, Bachmann A, Lössner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.

Diabetes Care. 2009 Jan;32(1):126-8. Epub 2008 Oct 7.PMID: 18840768 [PubMed - in process]Related articlesFree article

The inflammatory process of adipose tissue.

Blüher M.

Pediatr Endocrinol Rev. 2008 Sep;6(1):24-31. Review.PMID: 18806722 [PubMed - indexed for MEDLINE]Related articles

Adipokines influencing metabolic and cardiovascular disease are differentially regulated in maintenance hemodialysis.

Ziegelmeier M, Bachmann A, Seeger J, Lossner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.

Metabolism. 2008 Oct;57(10):1414-21.PMID: 18803947 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.

Kovacs P, Berndt J, Ruschke K, Klöting N, Schön MR, Körner A, Stumvoll M, Blüher M.

Metabolism. 2008 Sep;57(9):1227-31.PMID: 18702948 [PubMed - indexed for MEDLINE]Related articles

Endogenous soluble receptor for advanced glycation endproducts is increased in preeclampsia.

Fasshauer M, Seeger J, Waldeyer T, Schrey S, Ebert T, Lossner U, Bluher M, Stumvoll M, Faber R, Stepan H.

J Hypertens. 2008 Sep;26(9):1824-8.PMID: 18698218 [PubMed - indexed for MEDLINE]Related articles

Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.

Shai I, Schwarzfuchs D, Henkin Y, Shahar DR, Witkow S, Greenberg I, Golan R, Fraser D, Bolotin A, Vardi H, Tangi-Rozental O, Zuk-Ramot R, Sarusi B, Brickner D, Schwartz Z, Sheiner E, Marko R, Katorza E, Thiery J, Fiedler GM, Blüher M, Stumvoll M, Stampfer MJ; Dietary Intervention Randomized Controlled Trial (DIRECT) Group.

N Engl J Med. 2008 Jul 17;359(3):229-41.PMID: 18635428 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue inhibitor of metalloproteinase-1 mRNA production and protein secretion are induced by interleukin-1 beta in 3T3-L1 adipocytes.

Weise S, Kralisch S, Sommer G, Lossner U, Bluher M, Stumvoll M, Fasshauer M.

J Endocrinol. 2008 Jul;198(1):169-74.PMID: 18577571 [PubMed - indexed for MEDLINE]Related articlesFree article

Does retinol-binding protein 4 cause or reflect fatty liver disease?

Blüher M, Tönjes A, Stumvoll M.

Hepatology. 2008 Jul;48(1):4-6. Review. No abstract available. PMID: 18570262 [PubMed - indexed for MEDLINE]Related articles

Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene.

Oberbach A, Lehmann S, Kirsch K, Krist J, Sonnabend M, Linke A, Tönjes A, Stumvoll M, Blüher M, Kovacs P.

Eur J Endocrinol. 2008 Aug;159(2):129-36. Epub 2008 May 9.PMID: 18469018 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic profile and nitric oxide synthase expression of skeletal muscle fibers are altered in patients with type 1 diabetes.

Fritzsche K, Blüher M, Schering S, Buchwalow IB, Kern M, Linke A, Oberbach A, Adams V, Punkt K.

Exp Clin Endocrinol Diabetes. 2008 Nov;116(10):606-13. Epub 2008 May 9.PMID: 18465682 [PubMed - indexed for MEDLINE]Related articles

The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes.

Sommer G, Weise S, Kralisch S, Scherer PE, Lössner U, Blüher M, Stumvoll M, Fasshauer M.

J Cell Biochem. 2008 Aug 15;104(6):2241-7.PMID: 18452164 [PubMed - indexed for MEDLINE]Related articles

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth.

Klöting N, Koch L, Wunderlich T, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M.

Diabetes. 2008 Aug;57(8):2074-82. Epub 2008 Apr 28.PMID: 18443199 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum levels of the adipokine adipocyte fatty acid-binding protein are increased in preeclampsia.

Fasshauer M, Seeger J, Waldeyer T, Schrey S, Ebert T, Kratzsch J, Lössner U, Blüher M, Stumvoll M, Faber R, Stepan H.

Am J Hypertens. 2008 May;21(5):582-6. Epub 2008 Mar 13.PMID: 18437151 [PubMed - indexed for MEDLINE]Related articles

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance.

Kintscher U, Hartge M, Hess K, Foryst-Ludwig A, Clemenz M, Wabitsch M, Fischer-Posovszky P, Barth TF, Dragun D, Skurk T, Hauner H, Blüher M, Unger T, Wolf AM, Knippschild U, Hombach V, Marx N.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1304-10. Epub 2008 Apr 17.PMID: 18420999 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum levels of adipocyte fatty acid-binding protein (AFABP) are increased in chronic haemodialysis (CD).

Sommer G, Ziegelmeier M, Bachmann A, Kralisch S, Lossner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.

Clin Endocrinol (Oxf). 2008 Dec;69(6):901-5. Epub 2008 Apr 16.PMID: 18419784 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of the weight-loss drug rimonabant.

Blüher M.

Lancet. 2008 Feb 16;371(9612):555-6; author reply 556-7. No abstract available. PMID: 18280321 [PubMed - indexed for MEDLINE]Related articles

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.

Klöting N, Schleinitz D, Ruschke K, Berndt J, Fasshauer M, Tönjes A, Schön MR, Kovacs P, Stumvoll M, Blüher M.

Diabetologia. 2008 Apr;51(4):641-7. Epub 2008 Feb 5.PMID: 18251005 [PubMed - indexed for MEDLINE]Related articles

R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians.

Böttcher Y, Schleinitz D, Tönjes A, Blüher M, Stumvoll M, Kovacs P.

J Hum Genet. 2008;53(4):365-7. Epub 2008 Jan 31.PMID: 18231709 [PubMed - indexed for MEDLINE]Related articles

Circulating high-molecular-weight adiponectin is upregulated in preeclampsia and is related to insulin sensitivity and renal function.

Fasshauer M, Waldeyer T, Seeger J, Schrey S, Ebert T, Kratzsch J, Lössner U, Blüher M, Stumvoll M, Faber R, Stepan H.

Eur J Endocrinol. 2008 Feb;158(2):197-201.PMID: 18230826 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose triglyceride lipase gene expression in human visceral obesity.

Berndt J, Kralisch S, Klöting N, Ruschke K, Kern M, Fasshauer M, Schön MR, Stumvoll M, Blüher M.

Exp Clin Endocrinol Diabetes. 2008 Apr;116(4):203-10. Epub 2007 Dec 10.PMID: 18072017 [PubMed - indexed for MEDLINE]Related articles