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A 4 year follow-up study of cognitive functioning in patients with type 2 diabetes mellitus.

van den Berg E, Reijmer YD, de Bresser J, Kessels RP, Kappelle LJ, Biessels GJ; on behalf of the Utrecht Diabetic Encephalopathy Study Group.

Diabetologia. 2009 Oct 31. [Epub ahead of print]PMID: 19882137 [PubMed - as supplied by publisher]Related articles

MR spectroscopy of cerebral white matter in type 2 diabetes; no association with clinical variables and cognitive performance.

Tiehuis A, van der Meer F, Mali W, Pleizier M, Biessels GJ, Kappelle J, Luijten P.

Neuroradiology. 2009 Sep 30. [Epub ahead of print]PMID: 19789860 [PubMed - as supplied by publisher]Related articles

Acute myocardial infarction complicating subarachnoid haemorrhage.

van der Velden LB, Otterspoor LC, Schultze Kool LJ, Biessels GJ, Verheugt FW.

Neth Heart J. 2009 Aug;17(7-8):284-7.PMID: 19789696 [PubMed - in process]Related articlesFree article

Blood pressure levels in pre-diabetic stages are associated with worse cognitive functioning in patients with type 2 diabetes.

van den Berg E, Dekker JM, Nijpels G, Kessels RP, Kappelle LJ, de Haan EH, Heine RJ, Stehouwer CD, Biessels GJ.

Diabetes Metab Res Rev. 2009 Oct;25(7):657-64.PMID: 19768735 [PubMed - in process]Related articles

Diabetes: hypoglycemia and dementia in type 2 diabetes: chick or egg?

Biessels GJ.

Nat Rev Endocrinol. 2009 Oct;5(10):532-4. No abstract available. PMID: 19763124 [PubMed - in process]Related articles

Efficacy and safety of two 5 day insulin dosing regimens to achieve strict glycaemic control in patients with acute ischaemic stroke.

Vriesendorp TM, Roos YB, Kruyt ND, Biessels GJ, Kappelle LJ, Vermeulen M, Holleman F, DeVries JH, Hoekstra JB.

J Neurol Neurosurg Psychiatry. 2009 Sep;80(9):1040-3.PMID: 19684236 [PubMed - indexed for MEDLINE]Related articles

White matter lesions and brain atrophy: more than shared risk factors? A systematic review.

Appelman AP, Exalto LG, van der Graaf Y, Biessels GJ, Mali WP, Geerlings MI.

Cerebrovasc Dis. 2009;28(3):227-42. Epub 2009 Jul 2. Review.PMID: 19571536 [PubMed - indexed for MEDLINE]Related articles

Subjecting Acute Ischemic Stroke Patients to Continuous Tube Feeding and an Intensive Computerized Protocol Establishes Tight Glycemic Control.

Kruyt ND, Biessels GJ, Vriesendorp TM, Devries JH, Hoekstra JB, Elbers PW, Kappelle LJ, Portegies P, Vermeulen M, Roos YB.

Neurocrit Care. 2009 May 27. [Epub ahead of print]PMID: 19472086 [PubMed - as supplied by publisher]Related articles

Hyperglycemia and clinical outcome in aneurysmal subarachnoid hemorrhage: a meta-analysis.

Kruyt ND, Biessels GJ, de Haan RJ, Vermeulen M, Rinkel GJ, Coert B, Roos YB.

Stroke. 2009 Jun;40(6):e424-30. Epub 2009 Apr 23. Review.PMID: 19390078 [PubMed - indexed for MEDLINE]Related articles

Cognition in the early stage of type 2 diabetes.

Ruis C, Biessels GJ, Gorter KJ, van den Donk M, Kappelle LJ, Rutten GE.

Diabetes Care. 2009 Jul;32(7):1261-5. Epub 2009 Apr 14.PMID: 19366968 [PubMed - indexed for MEDLINE]Related articlesFree article

Cognitive dysfunction and its clinical and radiological determinants in patients with symptomatic arterial disease and diabetes.

Tiehuis AM, Mali WP, van Raamt AF, Visseren FL, Biessels GJ, van Zandvoort MJ, Kappelle LJ, van der Graaf Y; SMART Study Group.

J Neurol Sci. 2009 Aug 15;283(1-2):170-4. Epub 2009 Mar 6.PMID: 19268970 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: A systematic comparison of their impact on cognition.

van den Berg E, Kloppenborg RP, Kessels RP, Kappelle LJ, Biessels GJ.

Biochim Biophys Acta. 2009 May;1792(5):470-81. Epub 2008 Sep 23. Review.PMID: 18848880 [PubMed - indexed for MEDLINE]Related articles

Cognitive functioning in elderly persons with type 2 diabetes and metabolic syndrome: the Hoorn study.

van den Berg E, Dekker JM, Nijpels G, Kessels RP, Kappelle LJ, de Haan EH, Heine RJ, Stehouwer CD, Biessels GJ.

Dement Geriatr Cogn Disord. 2008;26(3):261-9. Epub 2008 Oct 8.PMID: 18841011 [PubMed - indexed for MEDLINE]Related articles

Construction of periventricular white matter hyperintensity maps by spatial normalization of the lateral ventricles.

Jongen C, van der Grond J, Anbeek P, Viergever MA, Biessels GJ, Pluim JP; Utrecht Diabetic Encephalopathy Study Group.

Hum Brain Mapp. 2009 Jul;30(7):2056-62.PMID: 18830954 [PubMed - indexed for MEDLINE]Related articles

Cognitive dysfunction and diabetes: implications for primary care.

Biessels GJ, Kerssen A, de Haan EH, Kappelle LJ.

Prim Care Diabetes. 2007 Dec;1(4):187-93. Epub 2007 Nov 26. Review.PMID: 18632044 [PubMed - indexed for MEDLINE]Related articles

Cerebral perfusion in relation to cognitive function and type 2 diabetes.

Tiehuis AM, Vincken KL, van den Berg E, Hendrikse J, Manschot SM, Mali WP, Kappelle LJ, Biessels GJ.

Diabetologia. 2008 Jul;51(7):1321-6. Epub 2008 May 17.PMID: 18488188 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural brain imaging in diabetes: a methodological perspective.

Jongen C, Biessels GJ.

Eur J Pharmacol. 2008 May 6;585(1):208-18. Epub 2008 Mar 4. Review.PMID: 18407264 [PubMed - indexed for MEDLINE]Related articles

High mean fasting glucose levels independently predict poor outcome and delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage.

Kruyt ND, Roos YW, Dorhout Mees SM, van den Bergh WM, Algra A, Rinkel GJ, Biessels GJ.

J Neurol Neurosurg Psychiatry. 2008 Dec;79(12):1382-5. Epub 2008 Apr 10.PMID: 18403438 [PubMed - indexed for MEDLINE]Related articles

Diabetes and other vascular risk factors for dementia: which factor matters most? A systematic review.

Kloppenborg RP, van den Berg E, Kappelle LJ, Biessels GJ.

Eur J Pharmacol. 2008 May 6;585(1):97-108. Epub 2008 Mar 4. Review.PMID: 18395201 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia and cognitive outcome after ischemic stroke.

Kruyt ND, Nys GM, van der Worp HB, van Zandvoort MJ, Kappelle LJ, Biessels GJ.

J Neurol Sci. 2008 Jul 15;270(1-2):141-7. Epub 2008 Apr 2.PMID: 18387635 [PubMed - indexed for MEDLINE]Related articles

Diabetes increases atrophy and vascular lesions on brain MRI in patients with symptomatic arterial disease.

Tiehuis AM, van der Graaf Y, Visseren FL, Vincken KL, Biessels GJ, Appelman AP, Kappelle LJ, Mali WP; SMART Study Group.

Stroke. 2008 May;39(5):1600-3. Epub 2008 Mar 27.PMID: 18369167 [PubMed - indexed for MEDLINE]Related articlesFree article

Cognition and diabetes: a lifespan perspective.

Biessels GJ, Deary IJ, Ryan CM.

Lancet Neurol. 2008 Feb;7(2):184-90. Review.PMID: 18207116 [PubMed - indexed for MEDLINE]Related articles

Progressive dementia and mesiotemporal atrophy on brain MRI: neurosyphilis mimicking pre-senile Alzheimer's disease?

van Eijsden P, Veldink JH, Linn FH, Scheltens P, Biessels GJ.

Eur J Neurol. 2008 Feb;15(2):e14-5. Epub 2007 Dec 18. No abstract available. PMID: 18093152 [PubMed - indexed for MEDLINE]Related articles

Automated and visual scoring methods of cerebral white matter hyperintensities: relation with age and cognitive function.

Tiehuis AM, Vincken KL, Mali WP, Kappelle LJ, Anbeek P, Algra A, Biessels GJ.

Cerebrovasc Dis. 2008;25(1-2):59-66. Epub 2007 Nov 22.PMID: 18033959 [PubMed - indexed for MEDLINE]Related articles

Rapidly progressive coma, hydrocephalus and leukoencephalopathy as presenting features of leptomeningeal metastases.

Niermeijer JM, Somers M, Spliet W, Reijneveld JC, Biessels GJ.

J Neurol. 2007 Dec;254(12):1757-8. Epub 2007 Nov 15. No abstract available. PMID: 18004643 [PubMed - indexed for MEDLINE]Related articles

Peripheral and central neurologic complications in type 2 diabetes mellitus: no association in individual patients.

Manschot SM, Biessels GJ, Rutten GE, Kessels RP, Gispen WH, Kappelle LJ; Utrecht Diabetic Encephalopathy Study Group.

J Neurol Sci. 2008 Jan 15;264(1-2):157-62. Epub 2007 Sep 12. Erratum in: J Neurol Sci. 2008 Dec 15;275(1-2):200. Kessels, R C [corrected to Kessels, R P]. PMID: 17850822 [PubMed - indexed for MEDLINE]Related articles

The metabolic syndrome is associated with decelerated cognitive decline in the oldest old.

van den Berg E, Biessels GJ, de Craen AJ, Gussekloo J, Westendorp RG.

Neurology. 2007 Sep 4;69(10):979-85.PMID: 17785666 [PubMed - indexed for MEDLINE]Related articles

Metabolic and vascular determinants of impaired cognitive performance and abnormalities on brain magnetic resonance imaging in patients with type 2 diabetes.

Manschot SM, Biessels GJ, de Valk H, Algra A, Rutten GE, van der Grond J, Kappelle LJ; Utrecht Diabetic Encephalopathy Study Group.

Diabetologia. 2007 Nov;50(11):2388-97. Epub 2007 Sep 2.PMID: 17764005 [PubMed - indexed for MEDLINE]Related articlesFree article

Automated measurement of brain and white matter lesion volume in type 2 diabetes mellitus.

Jongen C, van der Grond J, Kappelle LJ, Biessels GJ, Viergever MA, Pluim JP; Utrecht Diabetic Encephalopathy Study Group.

Diabetologia. 2007 Jul;50(7):1509-16. Epub 2007 May 11.PMID: 17492428 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes, cognitive function and dementia: vascular and metabolic determinants.

van den Berg E, Kessels RP, Kappelle LJ, de Haan EH, Biessels GJ; Utrecht Diabetic Encephalopathy Study Group.

Timely Top Med Cardiovasc Dis. 2007 Feb 23;11:E7.PMID: 17380217 [PubMed]Related articlesFree article

Cognitive functioning and brain MRI in patients with type 1 and type 2 diabetes mellitus: a comparative study.

Brands AM, Biessels GJ, Kappelle LJ, de Haan EH, de Valk HW, Algra A, Kessels RP; Utrecht Diabetic Encephalopathy Study Group.

Dement Geriatr Cogn Disord. 2007;23(5):343-50. Epub 2007 Mar 20.PMID: 17374953 [PubMed - indexed for MEDLINE]Related articles

[A combined protocol using CT, CT perfusion and CT angiography for the evaluation of cerebral ischemia]

Tiehuis AM, Biessels GJ, Velthuis BK, Ramos LM, Mali WP, Kappelle LJ.

Ned Tijdschr Geneeskd. 2007 Jan 20;151(3):177-83. Review. Dutch. PMID: 17288342 [PubMed - indexed for MEDLINE]Related articles

A detailed profile of cognitive dysfunction and its relation to psychological distress in patients with type 2 diabetes mellitus.

Brands AM, Van den Berg E, Manschot SM, Biessels GJ, Kappelle LJ, De Haan EH, Kessels RP.

J Int Neuropsychol Soc. 2007 Mar;13(2):288-97.PMID: 17286886 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes, cognitive function and dementia: vascular and metabolic determinants.

van den Berg E, Kessels RP, Kappelle LJ, de Haan EH, Biessels GJ; Utrecht Diabetic Encephalopathy Study Group.

Drugs Today (Barc). 2006 Nov;42(11):741-54. Review.PMID: 17171193 [PubMed - indexed for MEDLINE]Related articles

Brain imaging in patients with diabetes: a systematic review.

van Harten B, de Leeuw FE, Weinstein HC, Scheltens P, Biessels GJ.

Diabetes Care. 2006 Nov;29(11):2539-48. Review. No abstract available. PMID: 17065699 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study.

van den Berg E, de Craen AJ, Biessels GJ, Gussekloo J, Westendorp RG.

Diabetologia. 2006 Sep;49(9):2015-23. Epub 2006 Jun 28.PMID: 16804671 [PubMed - indexed for MEDLINE]Related articles

Cognitive performance, psychological well-being, and brain magnetic resonance imaging in older patients with type 1 diabetes.

Brands AM, Kessels RP, Hoogma RP, Henselmans JM, van der Beek Boter JW, Kappelle LJ, de Haan EH, Biessels GJ.

Diabetes. 2006 Jun;55(6):1800-6.PMID: 16731845 [PubMed - indexed for MEDLINE]Related articlesFree article

Voxel-based morphometry demonstrates reduced grey matter density on brain MRI in patients with diabetic retinopathy.

Wessels AM, Simsek S, Remijnse PL, Veltman DJ, Biessels GJ, Barkhof F, Scheltens P, Snoek FJ, Heine RJ, Rombouts SA.

Diabetologia. 2006 Oct;49(10):2474-80. Epub 2006 May 16.PMID: 16703329 [PubMed - indexed for MEDLINE]Related articles

Diabetic encephalopathy: A concept in need of a definition.

Mijnhout GS, Scheltens P, Diamant M, Biessels GJ, Wessels AM, Simsek S, Snoek FJ, Heine RJ.

Diabetologia. 2006 Jun;49(6):1447-8. Epub 2006 Apr 6. No abstract available. PMID: 16598451 [PubMed - indexed for MEDLINE]Related articles

Cerebrovascular reserve capacity is preserved in a population-based sample of patients with type 2 diabetes mellitus.

van Oers CA, Manschot SM, van Huffelen AC, Kappelle LJ, Biessels GJ; Utrecht Diabetic Encephalopathy Study Group.

Cerebrovasc Dis. 2006;22(1):46-50. Epub 2006 Mar 27.PMID: 16567937 [PubMed - indexed for MEDLINE]Related articles

Brain magnetic resonance imaging correlates of impaired cognition in patients with type 2 diabetes.

Manschot SM, Brands AM, van der Grond J, Kessels RP, Algra A, Kappelle LJ, Biessels GJ; Utrecht Diabetic Encephalopathy Study Group.

Diabetes. 2006 Apr;55(4):1106-13.PMID: 16567535 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiopulmonary bypass and long-term neurocognitive dysfunction in the rat.

Dieleman JM, de Lange F, Houston RJ, Biessels GJ, Bär PR, Mackensen GB, Grocott HP, Kalkman CJ.

Life Sci. 2006 Jul 4;79(6):551-8. Epub 2006 Feb 28.PMID: 16504211 [PubMed - indexed for MEDLINE]Related articles

Increased cortical atrophy in patients with Alzheimer's disease and type 2 diabetes mellitus.

Biessels GJ, De Leeuw FE, Lindeboom J, Barkhof F, Scheltens P.

J Neurol Neurosurg Psychiatry. 2006 Mar;77(3):304-7.PMID: 16484636 [PubMed - indexed for MEDLINE]Related articlesFree article

Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats.

Kamal A, Biessels GJ, Gispen WH, Ramakers GM.

Brain Res. 2006 Feb 16;1073-1074:276-80. Epub 2006 Feb 7.PMID: 16455062 [PubMed - indexed for MEDLINE]Related articles

Risk of dementia in diabetes mellitus: a systematic review.

Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P.

Lancet Neurol. 2006 Jan;5(1):64-74. Review. Erratum in: Lancet Neurol. 2006 Feb;5(2):113. PMID: 16361024 [PubMed - indexed for MEDLINE]Related articles

Diabetes and cognitive impairment. Clinical diagnosis and brain imaging in patients attending a memory clinic.

Biessels GJ, Koffeman A, Scheltens P.

J Neurol. 2006 Apr;253(4):477-82. Epub 2005 Nov 14.PMID: 16283097 [PubMed - indexed for MEDLINE]Related articles

Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?

Biessels GJ, Kappelle LJ; Utrecht Diabetic Encephalopathy Study Group.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1041-4. Review.PMID: 16246041 [PubMed - indexed for MEDLINE]Related articles

The impact of diabetes on cognition: what can be learned from rodent models?

Biessels GJ, Gispen WH.

Neurobiol Aging. 2005 Dec;26 Suppl 1:36-41. Epub 2005 Oct 11. Review.PMID: 16223548 [PubMed - indexed for MEDLINE]Related articles

Mild impairments in cognition in patients with type 2 diabetes mellitus: the use of the concepts MCI and CIND.

van den Berg E, Kessels RP, de Haan EH, Kappelle LJ, Biessels GJ.

J Neurol Neurosurg Psychiatry. 2005 Oct;76(10):1466-7. No abstract available. PMID: 16170101 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of short duration streptozotocin-induced diabetes mellitus on the late phase and threshold of long-term potentiation induction in the rat.

Kamal A, Biessels GJ, Ramakers GM, Hendrik Gispen W.

Brain Res. 2005 Aug 16;1053(1-2):126-30.PMID: 16038887 [PubMed - indexed for MEDLINE]Related articles