PubMed

Expression of Uncoupling Protein 1 in Mouse Brown Adipose Tissue Is Thyroid Hormone Receptor-{beta} Isoform Specific and Required for Adaptive Thermogenesis.

Ribeiro MO, Bianco SD, Kaneshige M, Schultz JJ, Cheng SY, Bianco AC, Brent GA.

Endocrinology. 2009 Nov 11. [Epub ahead of print]PMID: 19906816 [PubMed - as supplied by publisher]Related articles

Covering the base-pairs in iodothyronine deiodinase-1 biology: holes remain in the lineup.

Gereben B, Bianco AC.

Thyroid. 2009 Oct;19(10):1027-9. No abstract available. PMID: 19803788 [PubMed - in process]Related articles

A TRbeta-selective agonist confers resistance to diet-induced obesity.

Amorim BS, Ueta CB, Freitas BC, Nassif RJ, Gouveia CH, Christoffolete MA, Moriscot AS, Lancelloti CL, Llimona F, Barbeiro HV, de Souza HP, Catanozi S, Passarelli M, Aoki MS, Bianco AC, Ribeiro MO.

J Endocrinol. 2009 Nov;203(2):291-9. Epub 2009 Aug 27.PMID: 19713219 [PubMed - indexed for MEDLINE]Related articles

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase.

Zavacki AM, Arrojo E Drigo R, Freitas BC, Chung M, Harney JW, Egri P, Wittmann G, Fekete C, Gereben B, Bianco AC.

Mol Cell Biol. 2009 Oct;29(19):5339-47. Epub 2009 Aug 3.PMID: 19651899 [PubMed - indexed for MEDLINE]Related articles

Thyroid hormone-related regulation of gene expression in human fatty liver.

Pihlajamäki J, Boes T, Kim EY, Dearie F, Kim BW, Schroeder J, Mun E, Nasser I, Park PJ, Bianco AC, Goldfine AB, Patti ME.

J Clin Endocrinol Metab. 2009 Sep;94(9):3521-9. Epub 2009 Jun 23.PMID: 19549744 [PubMed - indexed for MEDLINE]Related articles

Mice lacking phosphatidylcholine transfer protein/StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue.

Kang HW, Ribich S, Kim BW, Hagen SJ, Bianco AC, Cohen DE.

J Lipid Res. 2009 Jun 6. [Epub ahead of print]PMID: 19502644 [PubMed - as supplied by publisher]Related articlesFree article

Triumphs of the thyroid despite lesser conversion.

Hall JA, Bianco AC.

Endocrinology. 2009 Jun;150(6):2502-4. No abstract available. PMID: 19458245 [PubMed - indexed for MEDLINE]Related articles

For some, L-thyroxine replacement might not be enough: a genetic rationale.

Kim BW, Bianco AC.

J Clin Endocrinol Metab. 2009 May;94(5):1521-3. Review. No abstract available. PMID: 19420275 [PubMed - indexed for MEDLINE]Related articles

Mice lacking brain-type creatine kinase activity show defective thermoregulation.

Streijger F, Pluk H, Oerlemans F, Beckers G, Bianco AC, Ribeiro MO, Wieringa B, Van der Zee CE.

Physiol Behav. 2009 Apr 20;97(1):76-86. Epub 2009 Feb 10.PMID: 19419668 [PubMed - indexed for MEDLINE]Related articles

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism.

Patti ME, Houten SM, Bianco AC, Bernier R, Larsen PR, Holst JJ, Badman MK, Maratos-Flier E, Mun EC, Pihlajamaki J, Auwerx J, Goldfine AB.

Obesity (Silver Spring). 2009 Sep;17(9):1671-7. Epub 2009 Apr 9.PMID: 19360006 [PubMed - indexed for MEDLINE]Related articles

Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes.

Grozovsky R, Ribich S, Rosene ML, Mulcahey MA, Huang SA, Patti ME, Bianco AC, Kim BW.

Endocrinology. 2009 Apr;150(4):1976-83. Epub 2008 Nov 26. Erratum in: Endocrinology. 2009 May;150(5):2499. PMID: 19036883 [PubMed - indexed for MEDLINE]Related articles

Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.

Gereben B, Zavacki AM, Ribich S, Kim BW, Huang SA, Simonides WS, Zeöld A, Bianco AC.

Endocr Rev. 2008 Dec;29(7):898-938. Epub 2008 Sep 24. Review.PMID: 18815314 [PubMed - indexed for MEDLINE]Related articles

Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton.

Capelo LP, Beber EH, Huang SA, Zorn TM, Bianco AC, Gouveia CH.

Bone. 2008 Nov;43(5):921-30. Epub 2008 Jul 17.PMID: 18682303 [PubMed - indexed for MEDLINE]Related articles

Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus.

Sánchez E, Singru PS, Acharya R, Bodria M, Fekete C, Zavacki AM, Bianco AC, Lechan RM.

Endocrinology. 2008 Sep;149(9):4329-35. Epub 2008 May 8.PMID: 18467436 [PubMed - indexed for MEDLINE]Related articlesFree article

The thyroid hormone-inactivating deiodinase functions as a homodimer.

Sagar GD, Gereben B, Callebaut I, Mornon JP, Zeöld A, Curcio-Morelli C, Harney JW, Luongo C, Mulcahey MA, Larsen PR, Huang SA, Bianco AC.

Mol Endocrinol. 2008 Jun;22(6):1382-93. Epub 2008 Mar 20.PMID: 18356288 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic effects of thyroid hormones-beyond traditional prospects.

Bianco AC.

Thyroid. 2008 Feb;18(2):99-100. No abstract available. PMID: 18279009 [PubMed - indexed for MEDLINE]Related articles

Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats.

Simonides WS, Mulcahey MA, Redout EM, Muller A, Zuidwijk MJ, Visser TJ, Wassen FW, Crescenzi A, da-Silva WS, Harney J, Engel FB, Obregon MJ, Larsen PR, Bianco AC, Huang SA.

J Clin Invest. 2008 Mar;118(3):975-83.PMID: 18259611 [PubMed - indexed for MEDLINE]Related articlesFree article

Reawakened interest in type III iodothyronine deiodinase in critical illness and injury.

Huang SA, Bianco AC.

Nat Clin Pract Endocrinol Metab. 2008 Mar;4(3):148-55. Epub 2008 Jan 22. Review.PMID: 18212764 [PubMed - indexed for MEDLINE]Related articles

Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide.

Adams BA, Gray SL, Isaac ER, Bianco AC, Vidal-Puig AJ, Sherwood NM.

Endocrinology. 2008 Apr;149(4):1571-80. Epub 2007 Dec 27.PMID: 18162530 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences.

Gereben B, Zeöld A, Dentice M, Salvatore D, Bianco AC.

Cell Mol Life Sci. 2008 Feb;65(4):570-90. Review.PMID: 17989921 [PubMed - indexed for MEDLINE]Related articles

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.

Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71. Epub 2007 Aug 24.PMID: 17720805 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study.

Olivares EL, Marassi MP, Fortunato RS, da Silva AC, Costa-e-Sousa RH, Araújo IG, Mattos EC, Masuda MO, Mulcahey MA, Huang SA, Bianco AC, Carvalho DP.

Endocrinology. 2007 Oct;148(10):4786-92. Epub 2007 Jul 12.PMID: 17628010 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain.

Fekete C, Freitas BC, Zeöld A, Wittmann G, Kádár A, Liposits Z, Christoffolete MA, Singru P, Lechan RM, Bianco AC, Gereben B.

Endocrinology. 2007 Oct;148(10):4865-74. Epub 2007 Jul 12.PMID: 17628004 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 iodothyronine deiodinase is highly expressed in germ cells of adult rat testis.

Wajner SM, dos Santos Wagner M, Melo RC, Parreira GG, Chiarini-Garcia H, Bianco AC, Fekete C, Sanchez E, Lechan RM, Maia AL.

J Endocrinol. 2007 Jul;194(1):47-54.PMID: 17592020 [PubMed - indexed for MEDLINE]Related articlesFree article

An inside job.

Bianco AC, Ribich S, Kim BW.

Endocrinology. 2007 Jul;148(7):3077-9. No abstract available. PMID: 17575061 [PubMed - indexed for MEDLINE]Related articlesFree article

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity.

Sagar GD, Gereben B, Callebaut I, Mornon JP, Zeöld A, da Silva WS, Luongo C, Dentice M, Tente SM, Freitas BC, Harney JW, Zavacki AM, Bianco AC.

Mol Cell Biol. 2007 Jul;27(13):4774-83. Epub 2007 Apr 23.PMID: 17452445 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue.

Souza SC, Christoffolete MA, Ribeiro MO, Miyoshi H, Strissel KJ, Stancheva ZS, Rogers NH, D'Eon TM, Perfield JW 2nd, Imachi H, Obin MS, Bianco AC, Greenberg AS.

J Lipid Res. 2007 Jun;48(6):1273-9. Epub 2007 Mar 30.PMID: 17401109 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.

Villicev CM, Freitas FR, Aoki MS, Taffarel C, Scanlan TS, Moriscot AS, Ribeiro MO, Bianco AC, Gouveia CH.

J Endocrinol. 2007 Apr;193(1):21-9.PMID: 17400799 [PubMed - indexed for MEDLINE]Related articlesFree article

The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation.

da-Silva WS, Harney JW, Kim BW, Li J, Bianco SD, Crescenzi A, Christoffolete MA, Huang SA, Bianco AC.

Diabetes. 2007 Mar;56(3):767-76.PMID: 17327447 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.

Christoffolete MA, Arrojo e Drigo R, Gazoni F, Tente SM, Goncalves V, Amorim BS, Larsen PR, Bianco AC, Zavacki AM.

Endocrinology. 2007 Mar;148(3):954-60. Epub 2006 Nov 30.PMID: 17138654 [PubMed - indexed for MEDLINE]Related articlesFree article

Deiodinases: implications of the local control of thyroid hormone action.

Bianco AC, Kim BW.

J Clin Invest. 2006 Oct;116(10):2571-9. Review.PMID: 17016550 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization.

Zeöld A, Pormüller L, Dentice M, Harney JW, Curcio-Morelli C, Tente SM, Bianco AC, Gereben B.

J Biol Chem. 2006 Oct 20;281(42):31538-43. Epub 2006 Aug 23.PMID: 16928685 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene.

Zeöld A, Doleschall M, Haffner MC, Capelo LP, Menyhért J, Liposits Z, da Silva WS, Bianco AC, Kacskovics I, Fekete C, Gereben B.

Endocrinology. 2006 Sep;147(9):4419-29. Epub 2006 May 25.PMID: 16728495 [PubMed - indexed for MEDLINE]Related articlesFree article

Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms.

Miyoshi H, Souza SC, Zhang HH, Strissel KJ, Christoffolete MA, Kovsan J, Rudich A, Kraemer FB, Bianco AC, Obin MS, Greenberg AS.

J Biol Chem. 2006 Jun 9;281(23):15837-44. Epub 2006 Apr 4.PMID: 16595669 [PubMed - indexed for MEDLINE]Related articlesFree article

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.

Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC, Auwerx J.

Nature. 2006 Jan 26;439(7075):484-9. Epub 2006 Jan 8.PMID: 16400329 [PubMed - indexed for MEDLINE]Related articles

Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.

Christoffolete MA, Ribeiro R, Singru P, Fekete C, da Silva WS, Gordon DF, Huang SA, Crescenzi A, Harney JW, Ridgway EC, Larsen PR, Lechan RM, Bianco AC.

Endocrinology. 2006 Apr;147(4):1735-43. Epub 2006 Jan 5.PMID: 16396983 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis.

Sharma V, Hays WR, Wood WM, Pugazhenthi U, St Germain DL, Bianco AC, Krezel W, Chambon P, Haugen BR.

Endocrinology. 2006 Mar;147(3):1438-51. Epub 2005 Nov 23.PMID: 16306084 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptive activation of thyroid hormone and energy expenditure.

Bianco AC, Maia AL, da Silva WS, Christoffolete MA.

Biosci Rep. 2005 Jun-Aug;25(3-4):191-208. Review.PMID: 16283553 [PubMed - indexed for MEDLINE]Related articles

[Prospective risk analysis in patients submitted to myocardial revascularization surgery]

Bianco AC, Timerman A, Paes AT, Gun C, Ramos RF, Freire RB, Vela CN, Fagundes Junior AA, Martins LC, Piegas LS.

Arq Bras Cardiol. 2005 Oct;85(4):254-61. Epub 2005 Nov 7. Portuguese. PMID: 16283031 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus.

Fekete C, Singru PS, Sanchez E, Sarkar S, Christoffolete MA, Riberio RS, Rand WM, Emerson CH, Bianco AC, Lechan RM.

Endocrinology. 2006 Jan;147(1):520-9. Epub 2005 Oct 6.PMID: 16210367 [PubMed - indexed for MEDLINE]Related articlesFree article

[Dopaminergic and somatostatinergic pathways decrease serum thyrotropin in rats bearing the 256-Walker mammary carcinoma]

Monte O, Zyngier S, Kimura ET, Bianco AC.

Arq Bras Endocrinol Metabol. 2005 Apr;49(2):253-64. Epub 2005 Sep 12. Portuguese. PMID: 16184254 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular and structural biology of the deiodinases.

Bianco AC, Larsen PR.

Thyroid. 2005 Aug;15(8):777-86. Review.PMID: 16131321 [PubMed - indexed for MEDLINE]Related articles

Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels.

Fekete C, Sarkar S, Christoffolete MA, Emerson CH, Bianco AC, Lechan RM.

Brain Res. 2005 Sep 14;1056(1):97-9.PMID: 16095572 [PubMed - indexed for MEDLINE]Related articles

LXRs regulate the balance between fat storage and oxidation.

Kalaany NY, Gauthier KC, Zavacki AM, Mammen PP, Kitazume T, Peterson JA, Horton JD, Garry DJ, Bianco AC, Mangelsdorf DJ.

Cell Metab. 2005 Apr;1(4):231-44.PMID: 16054068 [PubMed - indexed for MEDLINE]Related articles

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate.

Dentice M, Bandyopadhyay A, Gereben B, Callebaut I, Christoffolete MA, Kim BW, Nissim S, Mornon JP, Zavacki AM, Zeöld A, Capelo LP, Curcio-Morelli C, Ribeiro R, Harney JW, Tabin CJ, Bianco AC.

Nat Cell Biol. 2005 Jul;7(7):698-705. Epub 2005 Jun 19.PMID: 15965468 [PubMed - indexed for MEDLINE]Related articlesFree article

The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.

Canani LH, Capp C, Dora JM, Meyer EL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL.

J Clin Endocrinol Metab. 2005 Jun;90(6):3472-8. Epub 2005 Mar 29.PMID: 15797963 [PubMed - indexed for MEDLINE]Related articlesFree article

[Impact factor. The editor's report?]

Bianco AC.

Arq Bras Endocrinol Metabol. 2004 Jun;48(3):335-6. Epub 2004 Aug 26. Portuguese. No abstract available. PMID: 15640894 [PubMed - indexed for MEDLINE]Related articlesFree article

Triplets! Unexpected structural similarity among the three enzymes that catalyze initiation and termination of thyroid hormone effects.

Bianco AC.

Arq Bras Endocrinol Metabol. 2004 Feb;48(1):16-24. Epub 2004 Jun 1. Review.PMID: 15611815 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.

Zavacki AM, Ying H, Christoffolete MA, Aerts G, So E, Harney JW, Cheng SY, Larsen PR, Bianco AC.

Endocrinology. 2005 Mar;146(3):1568-75. Epub 2004 Dec 9.PMID: 15591136 [PubMed - indexed for MEDLINE]Related articlesFree article