PubMed

Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein.

Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, Weismann D, Hsiao JJ, Zhang D, Iwasaki T, Stark R, Flannery C, Kahn M, Carmean CM, Yu XX, Murray SF, Bhanot S, Monia BP, Cline GW, Samuel VT, Shulman GI.

Cell Metab. 2009 Dec;10(6):499-506.PMID: 19945407 [PubMed - in process]

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.

Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. Epub 2009 Jun 22.PMID: 19549853 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids.

Villanueva CJ, Monetti M, Shih M, Zhou P, Watkins SM, Bhanot S, Farese RV Jr.

Hepatology. 2009 Aug;50(2):434-42.PMID: 19472314 [PubMed - indexed for MEDLINE]Related articles

The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.

Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J, Zhang D, Jurczak MJ, Löffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S, Monia BP, Bogan JS, Samuel V, Shulman GI.

Cell Metab. 2009 Mar;9(3):252-64.PMID: 19254570 [PubMed - indexed for MEDLINE]Related articles

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

Swarbrick MM, Havel PJ, Levin AA, Bremer AA, Stanhope KL, Butler M, Booten SL, Graham JL, McKay RA, Murray SF, Watts LM, Monia BP, Bhanot S.

Endocrinology. 2009 Apr;150(4):1670-9. Epub 2009 Jan 22.PMID: 19164474 [PubMed - indexed for MEDLINE]Related articles

Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase.

Savransky V, Jun J, Li J, Nanayakkara A, Fonti S, Moser AB, Steele KE, Schweitzer MA, Patil SP, Bhanot S, Schwartz AR, Polotsky VY.

Circ Res. 2008 Nov 7;103(10):1173-80. Epub 2008 Oct 2.PMID: 18832746 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma.

Foryst-Ludwig A, Clemenz M, Hohmann S, Hartge M, Sprang C, Frost N, Krikov M, Bhanot S, Barros R, Morani A, Gustafsson JA, Unger T, Kintscher U.

PLoS Genet. 2008 Jun 27;4(6):e1000108.PMID: 18584035 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese mice.

Yu XX, Murray SF, Watts L, Booten SL, Tokorcheck J, Monia BP, Bhanot S.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E436-45. Epub 2008 Jun 3.PMID: 18523126 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of FDA's drug information centers.

Dada KC, Kremzner ME, Bhanot SK, Lal R.

Am J Health Syst Pharm. 2008 May 1;65(9):803-5. No abstract available. PMID: 18436726 [PubMed - indexed for MEDLINE]Related articles

Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression.

Yu XX, Pandey SK, Booten SL, Murray SF, Monia BP, Bhanot S.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E530-9. Epub 2008 Jan 15.PMID: 18198353 [PubMed - indexed for MEDLINE]Related articlesFree article

Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis.

Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM.

Hepatology. 2008 Feb;47(2):625-35.PMID: 18000880 [PubMed - indexed for MEDLINE]Related articles

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.

Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Biol Chem. 2007 Aug 3;282(31):22678-88. Epub 2007 May 27.PMID: 17526931 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific reduction of hepatic glucose 6-phosphate transporter-1 ameliorates diabetes while avoiding complications of glycogen storage disease.

Sloop KW, Showalter AD, Cox AL, Cao JX, Siesky AM, Zhang HY, Irizarry AR, Murray SF, Booten SL, Finger EA, McKay RA, Monia BP, Bhanot S, Michael MD.

J Biol Chem. 2007 Jun 29;282(26):19113-21. Epub 2007 May 3.PMID: 17478431 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM.

Hepatology. 2007 Jun;45(6):1366-74.PMID: 17476695 [PubMed - indexed for MEDLINE]Related articles

Reduction of low molecular weight protein-tyrosine phosphatase expression improves hyperglycemia and insulin sensitivity in obese mice.

Pandey SK, Yu XX, Watts LM, Michael MD, Sloop KW, Rivard AR, Leedom TA, Manchem VP, Samadzadeh L, McKay RA, Monia BP, Bhanot S.

J Biol Chem. 2007 May 11;282(19):14291-9. Epub 2007 Mar 12.PMID: 17353188 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease.

Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI.

J Clin Invest. 2007 Mar;117(3):739-45. Epub 2007 Feb 22.PMID: 17318260 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins.

Lam TK, Gutierrez-Juarez R, Pocai A, Bhanot S, Tso P, Schwartz GJ, Rossetti L.

Nat Med. 2007 Feb;13(2):171-80. Epub 2007 Feb 4.PMID: 17273170 [PubMed - indexed for MEDLINE]Related articles

Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes.

Liu Y, Michael MD, Kash S, Bensch WR, Monia BP, Murray SF, Otto KA, Syed SK, Bhanot S, Sloop KW, Sullivan JM, Reifel-Miller A.

Endocrinology. 2007 Feb;148(2):683-92. Epub 2006 Oct 26.PMID: 17068142 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action.

Samuel VT, Choi CS, Phillips TG, Romanelli AJ, Geisler JG, Bhanot S, McKay R, Monia B, Shutter JR, Lindberg RA, Shulman GI, Veniant MM.

Diabetes. 2006 Jul;55(7):2042-50.PMID: 16804074 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance.

Gutiérrez-Juárez R, Pocai A, Mulas C, Ono H, Bhanot S, Monia BP, Rossetti L.

J Clin Invest. 2006 Jun;116(6):1686-95.PMID: 16741579 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

Savage DB, Choi CS, Samuel VT, Liu ZX, Zhang D, Wang A, Zhang XM, Cline GW, Yu XX, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Clin Invest. 2006 Mar;116(3):817-24. Epub 2006 Feb 16.PMID: 16485039 [PubMed - indexed for MEDLINE]Related articlesFree article

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.

Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, Watts L, Booten SL, Graham M, McKay R, Subramaniam A, Propp S, Lollo BA, Freier S, Bennett CF, Bhanot S, Monia BP.

Cell Metab. 2006 Feb;3(2):87-98.PMID: 16459310 [PubMed - indexed for MEDLINE]Related articles

Modular surgical training for endoscopic extraperitoneal radical prostatectomy.

Stolzenburg JU, Schwaibold H, Bhanot SM, Rabenalt R, Do M, Truss M, Ho K, Anderson C.

BJU Int. 2005 Nov;96(7):1022-7.PMID: 16225521 [PubMed - indexed for MEDLINE]Related articles

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.

Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, Song XZ, Kelly S, Chen S, McKay R, Monia BP, Bhanot S.

Hepatology. 2005 Aug;42(2):362-71.PMID: 16001399 [PubMed - indexed for MEDLINE]Related articles

Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.

Liang Y, Osborne MC, Monia BP, Bhanot S, Watts LM, She P, DeCarlo SO, Chen X, Demarest K.

Metabolism. 2005 Jul;54(7):848-55.PMID: 15988691 [PubMed - indexed for MEDLINE]Related articles

Biological Age vs. Chronological Age.

Bhanot SM, Naik P, Gopalakrishanan R, Salkar DM, Naqashabandi K.

Eur Urol. 2005 Jul;48(1):168; author reply 168-170. Epub 2005 Apr 13. No abstract available. PMID: 15939528 [PubMed - indexed for MEDLINE]Related articles

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism.

Watts LM, Manchem VP, Leedom TA, Rivard AL, McKay RA, Bao D, Neroladakis T, Monia BP, Bodenmiller DM, Cao JX, Zhang HY, Cox AL, Jacobs SJ, Michael MD, Sloop KW, Bhanot S.

Diabetes. 2005 Jun;54(6):1846-53.PMID: 15919808 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice.

Buettner C, Patel R, Muse ED, Bhanot S, Monia BP, McKay R, Obici S, Rossetti L.

J Clin Invest. 2005 May;115(5):1306-13.PMID: 15864350 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of resistin in diet-induced hepatic insulin resistance.

Muse ED, Obici S, Bhanot S, Monia BP, McKay RA, Rajala MW, Scherer PE, Rossetti L.

J Clin Invest. 2004 Jul;114(2):232-9.PMID: 15254590 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors.

Sloop KW, Cao JX, Siesky AM, Zhang HY, Bodenmiller DM, Cox AL, Jacobs SJ, Moyers JS, Owens RA, Showalter AD, Brenner MB, Raap A, Gromada J, Berridge BR, Monteith DK, Porksen N, McKay RA, Monia BP, Bhanot S, Watts LM, Michael MD.

J Clin Invest. 2004 Jun;113(11):1571-81.PMID: 15173883 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice.

Liang Y, Osborne MC, Monia BP, Bhanot S, Gaarde WA, Reed C, She P, Jetton TL, Demarest KT.

Diabetes. 2004 Feb;53(2):410-7.PMID: 14747292 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic glucose-lowering effects of rosiglitazone and bis(ethylmaltolato)oxovanadium(IV) in ZDF rats.

Yuen VG, Bhanot S, Battell ML, Orvig C, McNeill JH.

Can J Physiol Pharmacol. 2003 Nov;81(11):1049-55.PMID: 14719040 [PubMed - indexed for MEDLINE]Related articles

Heat versus drugs in the treatment of benign prostatic hyperplasia.

Bhanot S.

BJU Int. 2003 Jul;92(1):152. No abstract available. PMID: 12823404 [PubMed - indexed for MEDLINE]Related articles

Post-biopsy rise in serum PSA. A potential tool for the dynamic evaluation of prostate cancer/prostatic intraepithelial neoplasia (PIN).

Bhanot S, Gopalakrishnan R, Oliver RT.

Cancer Biol Ther. 2003 Jan-Feb;2(1):67-70.PMID: 12673120 [PubMed - indexed for MEDLINE]Related articles

Preparation and characterization of vanadyl complexes with bidentate maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential.

Thompson KH, Liboiron BD, Sun Y, Bellman KD, Setyawati IA, Patrick BO, Karunaratne V, Rawji G, Wheeler J, Sutton K, Bhanot S, Cassidy C, McNeill JH, Yuen VG, Orvig C.

J Biol Inorg Chem. 2003 Jan;8(1-2):66-74. Epub 2002 Sep 12.PMID: 12459900 [PubMed - indexed for MEDLINE]Related articles

Effects of age and anesthetic on plasma glucose and insulin levels and insulin sensitivity in spontaneously hypertensive and Wistar rats.

Vera ER, Battell ML, Bhanot S, McNeill JH.

Can J Physiol Pharmacol. 2002 Oct;80(10):962-70.PMID: 12450062 [PubMed - indexed for MEDLINE]Related articles

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.

Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, Crosby S, Butler M, Murray SF, McKay RA, Bhanot S, Monia BP, Jirousek MR.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11357-62. Epub 2002 Aug 8.PMID: 12169659 [PubMed - indexed for MEDLINE]Related articlesFree article

The efficacy of resorbable plates in head and neck reconstruction.

Bhanot S, Alex JC, Lowlicht RA, Ross DA, Sasaki CT.

Laryngoscope. 2002 May;112(5):890-8.PMID: 12150624 [PubMed - indexed for MEDLINE]Related articles

Smiley incision: a direct surgical approach for retropubic radical prostatectomy.

Bhanot SM, Gopalakrishanan R.

Urology. 2002 Jul;60(1):149-51.PMID: 12100944 [PubMed - indexed for MEDLINE]Related articles

Counselling patients before rectal examination.

Bhanot S.

Hosp Med. 2002 Jun;63(6):374. No abstract available. PMID: 12096674 [PubMed - indexed for MEDLINE]Related articles

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice.

Butler M, McKay RA, Popoff IJ, Gaarde WA, Witchell D, Murray SF, Dean NM, Bhanot S, Monia BP.

Diabetes. 2002 Apr;51(4):1028-34.PMID: 11916922 [PubMed - indexed for MEDLINE]Related articlesFree article

Current applications of platelet gels in facial plastic surgery.

Bhanot S, Alex JC.

Facial Plast Surg. 2002 Feb;18(1):27-33. Review.PMID: 11823930 [PubMed - indexed for MEDLINE]Related articles

In vivo effects of insulin and bis(maltolato)oxovanadium (IV) on PKB activity in the skeletal muscle and liver of diabetic rats.

Marzban L, Bhanot S, McNeill JH.

Mol Cell Biochem. 2001 Jul;223(1-2):147-57.PMID: 11681716 [PubMed - indexed for MEDLINE]Related articles

In vivo effects of vanadium in diabetic rats are independent of changes in PI-3 kinase activity in skeletal muscle.

Mohammad A, Bhanot S, McNeill JH.

Mol Cell Biochem. 2001 Jul;223(1-2):103-8.PMID: 11681710 [PubMed - indexed for MEDLINE]Related articles

The chemical and biological aspects of fluoroquinolones: reality and dreams.

Bhanot SK, Singh M, Chatterjee NR.

Curr Pharm Des. 2001 Mar;7(5):311-35. Review.PMID: 11254892 [PubMed - indexed for MEDLINE]Related articles

Effects of bis(maltolato) oxovanadium (IV) on protein serine kinases in skeletal muscle of streptozotocin-diabetic rats.

Bhanot S, Girn J, Poucheret P, McNeill JH.

Mol Cell Biochem. 1999 Dec;202(1-2):131-40.PMID: 10706003 [PubMed - indexed for MEDLINE]Related articles

In vivo regulation of protein-serine kinases by insulin in skeletal muscle of fructose-hypertensive rats.

Bhanot S, Salh BS, Verma S, McNeill JH, Pelech SL.

Am J Physiol. 1999 Aug;277(2 Pt 1):E299-307.PMID: 10444426 [PubMed - indexed for MEDLINE]Related articlesFree article

Sympathectomy prevents fructose-induced hyperinsulinemia and hypertension.

Verma S, Bhanot S, McNeill JH.

Eur J Pharmacol. 1999 Jun 4;373(2-3):R1-4.PMID: 10414447 [PubMed - indexed for MEDLINE]Related articles

Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland.

Aller SG, Lombardo ID, Bhanot S, Forrest JN Jr.

Am J Physiol. 1999 Feb;276(2 Pt 1):C442-9.PMID: 9950772 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct vasodepressor effects of pioglitazone in spontaneously hypertensive rats.

Verma S, Bhanot S, Arikawa E, Yao L, McNeill JH.

Pharmacology. 1998 Jan;56(1):7-16.PMID: 9467183 [PubMed - indexed for MEDLINE]Related articles