PubMed

Epigenetic opportunities and challenges in cancer.

Best JD, Carey N.

Drug Discov Today. 2009 Nov 6. [Epub ahead of print]PMID: 19897050 [PubMed - as supplied by publisher]Related articles

What does it cost to establish a practice-nurses-led clinical trial in general practice?

Blackberry ID, Furler JS, Young D, Best JD; The PEACH study investigators.

Med J Aust. 2009 Nov 2;191(9):492-495.PMID: 19883343 [PubMed - as supplied by publisher]Related articles

Correlation of thromboelastography with standard tests of anticoagulation in paediatric patients receiving extracorporeal life support.

Alexander DC, Butt WW, Best JD, Donath SM, Monagle PT, Shekerdemian LS.

Thromb Res. 2009 Aug 10. [Epub ahead of print]PMID: 19674773 [PubMed - as supplied by publisher]Related articles

The COACH program produces sustained improvements in cardiovascular risk factors and adherence to recommended medications-two years follow-up.

Jelinek M, Vale MJ, Liew D, Grigg L, Dart A, Hare DL, Best JD.

Heart Lung Circ. 2009 Dec;18(6):388-92. Epub 2009 Aug 3.PMID: 19648058 [PubMed - in process]Related articles

Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespecified analysis of a randomised controlled trial.

Rajamani K, Colman PG, Li LP, Best JD, Voysey M, D'Emden MC, Laakso M, Baker JR, Keech AC; FIELD study investigators.

Lancet. 2009 May 23;373(9677):1780-8.PMID: 19465233 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid treatment guidelines and cardiovascular risk for Aboriginal people in Central Australia.

Luke JN, Brown A, O'Neal DN, O'Dea K, Jenkins AJ, Kelaher M, Best JD, Rowley KG.

Med J Aust. 2009 May 18;190(10):552-6.PMID: 19450200 [PubMed - indexed for MEDLINE]Related articles

Novel orally bioavailable gamma-secretase inhibitors with excellent in vivo activity.

Keown LE, Collins I, Cooper LC, Harrison T, Madin A, Mistry J, Reilly M, Shaimi M, Welch CJ, Clarke EE, Lewis HD, Wrigley JD, Best JD, Murray F, Shearman MS.

J Med Chem. 2009 Jun 11;52(11):3441-4.PMID: 19432431 [PubMed - indexed for MEDLINE]Related articles

Increased coated-platelet levels in chronic haemodialysis patients.

Valaydon ZS, Lee P, Dale GL, Januszewski AS, Rowley KG, Nandurkar H, Karschimkus C, Best JD, Lyons TJ, Jenkins AJ.

Nephrology (Carlton). 2009 Apr;14(2):148-54.PMID: 19076292 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein concentrations are very high and more stable over time than the traditional vascular risk factors total cholesterol and systolic blood pressure in an Australian aboriginal cohort.

Shemesh T, Rowley KG, Jenkins AJ, Best JD, O'Dea K.

Clin Chem. 2009 Feb;55(2):336-41. Epub 2008 Dec 12.PMID: 19074519 [PubMed - indexed for MEDLINE]Related articles

Depression: an important comorbidity with metabolic syndrome in a general population.

Dunbar JA, Reddy P, Davis-Lameloise N, Philpot B, Laatikainen T, Kilkkinen A, Bunker SJ, Best JD, Vartiainen E, Kai Lo S, Janus ED.

Diabetes Care. 2008 Dec;31(12):2368-73. Epub 2008 Oct 3.PMID: 18835951 [PubMed - indexed for MEDLINE]Related articlesFree article

Zebrafish: An in vivo model for the study of neurological diseases.

Best JD, Alderton WK.

Neuropsychiatr Dis Treat. 2008 Jun;4(3):567-76.PMID: 18830398 [PubMed - in process]Related articlesFree article

Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles.

O'Neal DN, Piers LS, Iser DM, Rowley KG, Jenkins AJ, Best JD, O'Dea K.

Atherosclerosis. 2008 Dec;201(2):368-77. Epub 2008 Apr 6.PMID: 18599067 [PubMed - indexed for MEDLINE]Related articles

Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus.

Januszewski AS, Thomas MC, Karschimkus CS, Chung JS, Rowley KG, Nelson CL, O'Neal DN, Dragicevic G, Harper CA, Best JD, Jenkins AJ.

J Med Invest. 2008 Feb;55(1-2):29-36.PMID: 18319542 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress.

Hoffmann P, Woon J, Rowley KG, Karschimkus C, Nelson CL, Dragicevic G, O'Neal D, Wilson A, Croft KD, Mori TA, Kemp BE, Best JD, Jenkins AJ.

Diabetes Res Clin Pract. 2008 May;80(2):e1-3. Epub 2008 Mar 3.PMID: 18313786 [PubMed - indexed for MEDLINE]Related articles

Lower than expected morbidity and mortality for an Australian Aboriginal population: 10-year follow-up in a decentralised community.

Rowley KG, O'Dea K, Anderson I, McDermott R, Saraswati K, Tilmouth R, Roberts I, Fitz J, Wang Z, Jenkins A, Best JD, Wang Z, Brown A.

Med J Aust. 2008 Mar 3;188(5):283-7.PMID: 18312192 [PubMed - indexed for MEDLINE]Related articlesFree article

Low high-density lipoprotein-cholesterol is the most prevalent metabolic abnormality for Australian Aboriginal men and women even when lean.

Shemesh T, Rowley KG, Piers LS, Best JD, O'Dea K.

Eur J Cardiovasc Prev Rehabil. 2008 Feb;15(1):49-51.PMID: 18277185 [PubMed - indexed for MEDLINE]Related articles

Reduction of proteinuria by rosiglitazone in non-diabetic renal disease.

Kincaid-Smith P, Fairley KF, Farish S, Best JD, Proietto J.

Nephrology (Carlton). 2008 Feb;13(1):58-62.PMID: 18199105 [PubMed - indexed for MEDLINE]Related articles

Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes.

Jenkins AJ, Zhang SX, Rowley KG, Karschimkus CS, Nelson CL, Chung JS, O'Neal DN, Januszewski AS, Croft KD, Mori TA, Dragicevic G, Harper CA, Best JD, Lyons TJ, Ma JX.

Diabet Med. 2007 Dec;24(12):1345-51. Epub 2007 Oct 29.PMID: 17971181 [PubMed - indexed for MEDLINE]Related articles

Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project.

Laatikainen T, Dunbar JA, Chapman A, Kilkkinen A, Vartiainen E, Heistaro S, Philpot B, Absetz P, Bunker S, O'Neil A, Reddy P, Best JD, Janus ED.

BMC Public Health. 2007 Sep 19;7:249.PMID: 17877832 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-associative learning in larval zebrafish.

Best JD, Berghmans S, Hunt JJ, Clarke SC, Fleming A, Goldsmith P, Roach AG.

Neuropsychopharmacology. 2008 Apr;33(5):1206-15. Epub 2007 Jun 20.PMID: 17581529 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe combined hyperlipidaemia and retinal lipid infiltration in a patient with Type 2 diabetes mellitus.

Davey RA, Tebbutt NC, Favaloro JM, O'neal DN, Rae D, Zajac JD, Best JD.

Lipids Health Dis. 2006 Dec 17;5:29.PMID: 17173705 [PubMed - indexed for MEDLINE]Related articlesFree article

The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse.

Best JD, Smith DW, Reilly MA, O'Donnell R, Lewis HD, Ellis S, Wilkie N, Rosahl TW, Laroque PA, Boussiquet-Leroux C, Churcher I, Atack JR, Harrison T, Shearman MS.

J Pharmacol Exp Ther. 2007 Feb;320(2):552-8. Epub 2006 Nov 10.PMID: 17099072 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood pressure and hypertension for Australian Aboriginal and Torres Strait Islander people.

Wang Z, Knight S, Wilson A, Rowley KG, Best JD, McDermott R, Leonard D, Shaw JE, O'Dea K.

Eur J Cardiovasc Prev Rehabil. 2006 Jun;13(3):438-43.PMID: 16926675 [PubMed - indexed for MEDLINE]Related articles

Exercise frequency and arterial compliance in non-diabetic and type 1 diabetic individuals.

Mason NJ, Jenkins AJ, Best JD, Rowley KG.

Eur J Cardiovasc Prev Rehabil. 2006 Aug;13(4):598-603.PMID: 16874151 [PubMed - indexed for MEDLINE]Related articles

A comparative assessment of gamma-secretase activity in transgenic and non-transgenic rodent brain.

Goggi JL, Lewis HD, Mok J, Harrison T, Shearman MS, Atack JR, Best JD.

J Neurosci Methods. 2006 Oct 30;157(2):246-52. Epub 2006 Jul 21.PMID: 16859750 [PubMed - indexed for MEDLINE]Related articles

Widespread vascular production of C-reactive protein (CRP) and a relationship between serum CRP, plaque CRP and intimal hypertrophy.

Wilson AM, Swan JD, Ding H, Zhang Y, Whitbourn RJ, Gurry J, Yii M, Wilson AC, Hill M, Triggle C, Best JD, Jenkins AJ.

Atherosclerosis. 2007 Mar;191(1):175-81. Epub 2006 Jun 9.PMID: 16765355 [PubMed - indexed for MEDLINE]Related articles

Differential association of C-reactive protein with adiposity in men and women in an Aboriginal community in northeast Arnhem Land of Australia.

Shemesh T, Rowley KG, Jenkins A, Brimblecombe J, Best JD, O'Dea K.

Int J Obes (Lond). 2007 Jan;31(1):103-8. Epub 2006 May 9. Erratum in: Int J Obes (Lond). 2007 Mar;31(3):564. PMID: 16682979 [PubMed - indexed for MEDLINE]Related articles

Traditional risk factor assessment does not capture the extent of cardiovascular risk in systemic lupus erythematosus.

Lee AB, Godfrey T, Rowley KG, Karschimkus CS, Dragicevic G, Romas E, Clemens L, Wilson AM, Nikpour M, Prior DL, Best JD, Jenkins AJ.

Intern Med J. 2006 Apr;36(4):237-43.PMID: 16640741 [PubMed - indexed for MEDLINE]Related articles

In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat.

Best JD, Jay MT, Otu F, Churcher I, Reilly M, Morentin-Gutierrez P, Pattison C, Harrison T, Shearman MS, Atack JR.

J Pharmacol Exp Ther. 2006 May;317(2):786-90. Epub 2006 Jan 27.PMID: 16443723 [PubMed - indexed for MEDLINE]Related articlesFree article

4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.

Churcher I, Beher D, Best JD, Castro JL, Clarke EE, Gentry A, Harrison T, Hitzel L, Kay E, Kerrad S, Lewis HD, Morentin-Gutierrez P, Mortishire-Smith R, Oakley PJ, Reilly M, Shaw DE, Shearman MS, Teall MR, Williams S, Wrigley JD.

Bioorg Med Chem Lett. 2006 Jan 15;16(2):280-4. Epub 2005 Nov 3.PMID: 16275079 [PubMed - indexed for MEDLINE]Related articles

The metabolic syndrome and changing relationship between blood pressure and insulin with age, as observed in Aboriginal and Torres Strait Islander peoples.

Schutte AE, Shemesh T, Rowley K, Best JD, McDermott R, O'Dea K.

Diabet Med. 2005 Nov;22(11):1589-97.PMID: 16241926 [PubMed - indexed for MEDLINE]Related articles

Systemic and vascular inflammation is elevated in early IgA and type 1 diabetic nephropathies and relates to vascular disease risk factors and renal function.

Nelson CL, Karschimkus CS, Dragicevic G, Packham DK, Wilson AM, O'Neal D, Becker GJ, Best JD, Jenkins AJ.

Nephrol Dial Transplant. 2005 Nov;20(11):2420-6. Epub 2005 Aug 22.PMID: 16115854 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL and small LDL particle size are independently predictive of a selective defect in microcirculatory endothelial function in type 2 diabetes.

Woodman RJ, Watts GF, Playford DA, Best JD, Chan DC.

Diabetes Obes Metab. 2005 Sep;7(5):612-7.PMID: 16050955 [PubMed - indexed for MEDLINE]Related articles

Plasma low-molecular weight fluorescence in type 1 diabetes mellitus.

Januszewski AS, Thomas MC, Chung SJ, Karschimkus CS, Rowley KG, Nelson C, O'Neal D, Wang Z, Best JD, Jenkins AJ.

Ann N Y Acad Sci. 2005 Jun;1043:655-61.PMID: 16037289 [PubMed - indexed for MEDLINE]Related articles

Associations between liver histology and severity of the metabolic syndrome in subjects with nonalcoholic fatty liver disease.

Ryan MC, Wilson AM, Slavin J, Best JD, Jenkins AJ, Desmond PV.

Diabetes Care. 2005 May;28(5):1222-4. No abstract available. PMID: 15855597 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative measurement of changes in amyloid-beta(40) in the rat brain and cerebrospinal fluid following treatment with the gamma-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide].

Best JD, Jay MT, Otu F, Ma J, Nadin A, Ellis S, Lewis HD, Pattison C, Reilly M, Harrison T, Shearman MS, Williamson TL, Atack JR.

J Pharmacol Exp Ther. 2005 May;313(2):902-8. Epub 2005 Mar 2.PMID: 15743924 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of GLUT12 in the fetal membranes of the human placenta.

Gude NM, Stevenson JL, Murthi P, Rogers S, Best JD, Kalionis B, King RG.

Placenta. 2005 Jan;26(1):67-72.PMID: 15664413 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress and high-density lipoprotein function in Type I diabetes and end-stage renal disease.

Kalogerakis G, Baker AM, Christov S, Rowley KG, Dwyer K, Winterbourn C, Best JD, Jenkins AJ.

Clin Sci (Lond). 2005 Jun;108(6):497-506.PMID: 15634192 [PubMed - indexed for MEDLINE]Related articles

A novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core.

Lewis SJ, Smith AL, Neduvelil JG, Stevenson GI, Lindon MJ, Jones AB, Shearman MS, Beher D, Clarke E, Best JD, Peachey JE, Harrison T, Castro JL.

Bioorg Med Chem Lett. 2005 Jan 17;15(2):373-8.PMID: 15603957 [PubMed - indexed for MEDLINE]Related articles

Lipoproteins and diabetic microvascular complications.

Jenkins AJ, Rowley KG, Lyons TJ, Best JD, Hill MA, Klein RL.

Curr Pharm Des. 2004;10(27):3395-418. Review.PMID: 15544524 [PubMed - indexed for MEDLINE]Related articles

Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer.

Macheda ML, Rogers S, Best JD.

J Cell Physiol. 2005 Mar;202(3):654-62. Review.PMID: 15389572 [PubMed - indexed for MEDLINE]Related articles

'Lipoproteins, glycoxidation and diabetic angiopathy'.

Jenkins AJ, Best JD, Klein RL, Lyons TJ.

Diabetes Metab Res Rev. 2004 Sep-Oct;20(5):349-68. Review.PMID: 15343582 [PubMed - indexed for MEDLINE]Related articles

Paraoxonase activity in Greek migrants and Anglo-Celtic persons in the Melbourne Collaborative Cohort Study: relationship to dietary markers.

Lee CT, Rowley K, Jenkins AJ, O'Dea K, Itsiopoulos C, Stoney RM, Su Q, Giles GG, Best JD.

Eur J Nutr. 2005 Jun;44(4):223-30. Epub 2004 Jul 12.PMID: 15309416 [PubMed - indexed for MEDLINE]Related articles

Comparison of arterial assessments in low and high vascular disease risk groups.

Wilson AM, O'Neal D, Nelson CL, Prior DL, Best JD, Jenkins AJ.

Am J Hypertens. 2004 Apr;17(4):285-91.PMID: 15062880 [PubMed - indexed for MEDLINE]Related articles

Coaching patients On Achieving Cardiovascular Health (COACH): a multicenter randomized trial in patients with coronary heart disease.

Vale MJ, Jelinek MV, Best JD, Dart AM, Grigg LE, Hare DL, Ho BP, Newman RW, McNeil JJ; COACH Study Group.

Arch Intern Med. 2003 Dec 8-22;163(22):2775-83.PMID: 14662633 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes.

Rogers S, Chandler JD, Clarke AL, Petrou S, Best JD.

Biochem Biophys Res Commun. 2003 Aug 29;308(3):422-6.PMID: 12914765 [PubMed - indexed for MEDLINE]Related articles

Low plasma concentrations of diet-derived antioxidants in association with microalbuminuria in Indigenous Australian populations.

Rowley K, O'Dea K, Su Q, Jenkins AJ, Best JD.

Clin Sci (Lond). 2003 Nov;105(5):569-75.PMID: 12826019 [PubMed - indexed for MEDLINE]Related articles

GLUT12 expression in human placenta in first trimester and term.

Gude NM, Stevenson JL, Rogers S, Best JD, Kalionis B, Huisman MA, Erwich JJ, Timmer A, King RG.

Placenta. 2003 May;24(5):566-70.PMID: 12744934 [PubMed - indexed for MEDLINE]Related articles

Inflammation and vascular endothelial activation in an Aboriginal population: relationships to coronary disease risk factors and nutritional markers.

Rowley K, Walker KZ, Cohen J, Jenkins AJ, O'Neal D, Su Q, Best JD, O'Dea K.

Med J Aust. 2003 May 19;178(10):495-500.PMID: 12741936 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of GLUT12 in breast cancer and normal breast tissue.

Rogers S, Docherty SE, Slavin JL, Henderson MA, Best JD.

Cancer Lett. 2003 Apr 25;193(2):225-33.PMID: 12706881 [PubMed - indexed for MEDLINE]Related articles