PubMed

Effects of ryanoids on spontaneous and depolarization-evoked calcium release events in frog muscle.

Hui CS, Besch HR Jr, Bidasee KR.

Biophys J. 2004 Jul;87(1):243-55.PMID: 15240461 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase.

Bidasee KR, Zhang Y, Shao CH, Wang M, Patel KP, Dincer UD, Besch HR Jr.

Diabetes. 2004 Feb;53(2):463-73.PMID: 14747299 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic diabetes alters function and expression of ryanodine receptor calcium-release channels in rat hearts.

Bidasee KR, Nallani K, Henry B, Dincer UD, Besch HR Jr.

Mol Cell Biochem. 2003 Jul;249(1-2):113-23.PMID: 12956406 [PubMed - indexed for MEDLINE]Related articles

Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels.

Bidasee KR, Nallani K, Yu Y, Cocklin RR, Zhang Y, Wang M, Dincer UD, Besch HR Jr.

Diabetes. 2003 Jul;52(7):1825-36.PMID: 12829653 [PubMed - indexed for MEDLINE]Related articlesFree article

Streptozotocin-induced diabetes increases disulfide bond formation on cardiac ryanodine receptor (RyR2).

Bidasee KR, Nallani K, Besch HR Jr, Dincer UD.

J Pharmacol Exp Ther. 2003 Jun;305(3):989-98. Epub 2003 Feb 20.PMID: 12606683 [PubMed - indexed for MEDLINE]Related articlesFree article

Diketopyridylryanodine has three concentration-dependent effects on the cardiac calcium-release channel/ryanodine receptor.

Bidasee KR, Xu L, Meissner G, Besch HR Jr.

J Biol Chem. 2003 Apr 18;278(16):14237-48. Epub 2003 Feb 3.PMID: 12566457 [PubMed - indexed for MEDLINE]Related articlesFree article

Ryanodine receptor dysfunction in hearts of streptozotocin-induced diabetic rats.

Bidasee KR, Dinçer UD, Besch HR Jr.

Mol Pharmacol. 2001 Dec;60(6):1356-64.PMID: 11723243 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of ryanodine on calcium sparks in cut twitch fibres of Rana temporaria.

Hui CS, Bidasee KR, Besch HR Jr.

J Physiol. 2001 Jul 15;534(Pt. 2):327-42.PMID: 11454954 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of complement of mRNA encoding inositol 1,4,5-trisphosphate receptor isoforms in rat tissues using relative-polymerase chain reaction.

Gersting JA, Bidasee KR, Dinçer UD, Besch HR Jr.

Anal Biochem. 2001 Jul 15;294(2):188-90. No abstract available. PMID: 11444817 [PubMed - indexed for MEDLINE]Related articles

Tectoridins modulate skeletal and cardiac muscle sarcoplasmic reticulum calcium-release channels.

Bidasee KR, Maxwell A, Reynolds WF, Patel V, Besch HR Jr.

J Pharmacol Exp Ther. 2000 Jun;293(3):1074-83.PMID: 10869412 [PubMed - indexed for MEDLINE]Related articlesFree article

Ryanodine and inositol trisphosphate receptors are differentially distributed and expressed in rat parotid gland.

Zhang X, Wen J, Bidasee KR, Besch HR Jr, Wojcikiewicz RJ, Lee B, Rubin RP.

Biochem J. 1999 Jun 1;340 ( Pt 2):519-27.PMID: 10333498 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure-function relationships among ryanodine derivatives. Pyridyl ryanodine definitively separates activation potency from high affinity.

Bidasee KR, Besch HR Jr.

J Biol Chem. 1998 May 15;273(20):12176-86.PMID: 9575165 [PubMed - indexed for MEDLINE]Related articlesFree article

The dose-response model for dioxin.

Byrd DM 3rd, Allen DO, Beamer RL, Besch HR Jr, Bylund DB, Doull J, Fleming WW, Fries A, Guengerich FP, Hornbrook R, Lasagna L, Lum BK, Michaelis EK, Morgan ET, Poland A, Rozman KK, Smith JB, Swanson HI, Waddell W, Wilson JD.

Risk Anal. 1998 Feb;18(1):1-2. No abstract available. PMID: 9556441 [PubMed - indexed for MEDLINE]Related articles

Ryanodine receptor expression is associated with intracellular Ca2+ release in rat parotid acinar cells.

Zhang X, Wen J, Bidasee KR, Besch HR Jr, Rubin RP.

Am J Physiol. 1997 Oct;273(4 Pt 1):C1306-14.PMID: 9357775 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural components of ryanodine responsible for modulation of sarcoplasmic reticulum calcium channel function.

Welch W, Williams AJ, Tinker A, Mitchell KE, Deslongchamps P, Lamothe J, Gerzon K, Bidasee KR, Besch HR Jr, Airey JA, Sutko JL, Ruest L.

Biochemistry. 1997 Mar 11;36(10):2939-50.PMID: 9062124 [PubMed - indexed for MEDLINE]Related articles

Amiodarone instilled into the canine pericardial sac migrates transmurally to produce electrophysiologic effects and suppress atrial fibrillation.

Ayers GM, Rho TH, Ben-David J, Besch HR Jr, Zipes DP.

J Cardiovasc Electrophysiol. 1996 Aug;7(8):713-21.PMID: 8856462 [PubMed - indexed for MEDLINE]Related articles

Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel.

Tinker A, Sutko JL, Ruest L, Deslongchamps P, Welch W, Airey JA, Gerzon K, Bidasee KR, Besch HR Jr, Williams AJ.

Biophys J. 1996 May;70(5):2110-9.PMID: 9172735 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation and deactivation of sarcoplasmic reticulum calcium release channels: molecular dissection of mechanisms via novel semi-synthetic ryanoids.

Bidasee KR, Besch HR Jr, Gerzon K, Humerickhouse RA.

Mol Cell Biochem. 1995 Aug-Sep;149-150:145-60.PMID: 8569724 [PubMed - indexed for MEDLINE]Related articles

Effect of experience on medical students' attitudes toward animal laboratories in pharmacology education.

Willis LR, Besch HR Jr.

Acad Med. 1995 Jan;70(1):67-9.PMID: 7826448 [PubMed - indexed for MEDLINE]Related articles

High affinity C10-Oeq ester derivatives of ryanodine. Activator-selective agonists of the sarcoplasmic reticulum calcium release channel.

Humerickhouse RA, Bidasee KR, Gerzon K, Emmick JT, Kwon S, Sutko JL, Ruest L, Besch HR Jr.

J Biol Chem. 1994 Dec 2;269(48):30243-53.PMID: 7982934 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural determinants of high-affinity binding of ryanoids to the vertebrate skeletal muscle ryanodine receptor: a comparative molecular field analysis.

Welch W, Ahmad S, Airey JA, Gerzon K, Humerickhouse RA, Besch HR Jr, Ruest L, Deslongchamps P, Sutko JL.

Biochemistry. 1994 May 24;33(20):6074-85.PMID: 8193121 [PubMed - indexed for MEDLINE]Related articles

Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes.

Emmick JT, Kwon S, Bidasee KR, Besch KT, Besch HR Jr.

J Pharmacol Exp Ther. 1994 May;269(2):717-24.PMID: 8182538 [PubMed - indexed for MEDLINE]Related articles

Differential activating and deactivating effects of natural ryanodine congeners on the calcium release channel of sarcoplasmic reticulum: evidence for separation of effects at functionally distinct sites.

Humerickhouse RA, Besch HR Jr, Gerzon K, Ruest L, Sutko JL, Emmick JT.

Mol Pharmacol. 1993 Aug;44(2):412-21.PMID: 8394996 [PubMed - indexed for MEDLINE]Related articles

Amino- and guanidinoacylryanodines: basic ryanodine esters with enhanced affinity for the sarcoplasmic reticulum Ca(2+)-release channel.

Gerzon K, Humerickhouse RA, Besch HR Jr, Bidasee KR, Emmick JT, Roeske RW, Tian Z, Ruest L, Sutko JL.

J Med Chem. 1993 May 14;36(10):1319-23.PMID: 8388466 [PubMed - indexed for MEDLINE]Related articles

Effects of ryanodine on cardiac subcellular membrane fractions.

Besch HR Jr.

Fed Proc. 1985 Dec;44(15):2960-3. Review.PMID: 2415404 [PubMed - indexed for MEDLINE]Related articles

The receptor concept: basic to clinical science.

Felten SY, Besch HR Jr.

J Indiana State Med Assoc. 1982 Sep;75(9):618-22. No abstract available. PMID: 6290572 [PubMed - indexed for MEDLINE]Related articles

Effects of streptozotocin diabetes on the noradrenergic innervation of the rat heart: a longitudinal histofluorescence and neurochemical study.

Felten SY, Peterson RG, Shea PA, Besch HR Jr, Felten DL.

Brain Res Bull. 1982 Jun;8(6):593-607.PMID: 6754009 [PubMed - indexed for MEDLINE]Related articles

Cardiac autonomic receptors. Recent concepts from radiolabeled ligand-binding studies.

Watanabe AM, Jones LR, Manalan AS, Besch HR Jr.

Circ Res. 1982 Feb;50(2):161-74. Review. No abstract available. PMID: 6120047 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung.

Manalan AS, Besch HR Jr, Watanabe AM.

Circ Res. 1981 Aug;49(2):326-36.PMID: 6113900 [PubMed - indexed for MEDLINE]Related articlesFree article

Unmasking effect of alamethicin on the (Na+,K+)-ATPase, beta-adrenergic receptor-coupled adenylate cyclase, and cAMP-dependent protein kinase activities of cardiac sarcolemmal vesicles.

Jones LR, Maddock SW, Besch HR Jr.

J Biol Chem. 1980 Oct 25;255(20):9971-80.PMID: 6253461 [PubMed - indexed for MEDLINE]Related articlesFree article

Patent and latent activities of cardiac membrane vesicles: distinctions between proteins of sarcolemma and sarcoplasmic reticulum.

Besch HR Jr, Jones LR.

Adv Myocardiol. 1980;1:123-38. No abstract available. PMID: 6248930 [PubMed - indexed for MEDLINE]Related articles

Thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, ATPase activities, and sialic acid content of rat cardiac membrane vesicles.

McConnaughey MM, Jones LR, Watanabe AM, Besch HR Jr, Williams LT, Lefkowitz RJ.

J Cardiovasc Pharmacol. 1979 Nov-Dec;1(6):609-23. No abstract available. PMID: 94627 [PubMed - indexed for MEDLINE]Related articles

Adrenergaically mediated ventricular fibrillation in probucol-treated dogs: roles of alpha and beta adrenergic receptors.

Elharrar V, Watanabe AM, Molello J, Besch HR Jr, Zipes DP.

Pacing Clin Electrophysiol. 1979 Jul;2(4):435-43.PMID: 95312 [PubMed - indexed for MEDLINE]Related articles

Ryanodine: its alterations of cat papillary muscle contractile state and responsiveness to inotropic interventions and a suggested mechanism of action.

Sutko JL, Willerson JT, Templeton GH, Jones LR, Besch HR Jr.

J Pharmacol Exp Ther. 1979 Apr;209(1):37-47.PMID: 430377 [PubMed - indexed for MEDLINE]Related articles

Indirect and direct effects of the divalent cation ionophore A23187 on guinea pig and rat ventricular myocardium.

Lindemann JP, Besch HR Jr, Watanabe AM.

Circ Res. 1979 Apr;44(4):472-82. No abstract available. PMID: 218747 [PubMed - indexed for MEDLINE]Related articlesFree article

Ryanodine-induced stimulation of net Ca++ uptake by cardiac sarcoplasmic reticulum vesicles.

Jones LR, Besch HR Jr, Sutko JL, Willerson JT.

J Pharmacol Exp Ther. 1979 Apr;209(1):48-55. No abstract available. PMID: 155157 [PubMed - indexed for MEDLINE]Related articles

Acetylcholine antagonism of the electrophysiological effects of isoproterenol on canine cardiac Purkinje fibers.

Bailey JC, Watanabe AM, Besch HR Jr, Lathrop DA.

Circ Res. 1979 Mar;44(3):378-83.PMID: 761320 [PubMed - indexed for MEDLINE]Related articlesFree article

Separation of vesicles of cardiac sarcolemma from vesicles of cardiac sarcoplasmic reticulum. Comparative biochemical analysis of component activities.

Jones LR, Besch HR Jr, Fleming JW, McConnaughey MM, Watanabe AM.

J Biol Chem. 1979 Jan 25;254(2):530-9.PMID: 216677 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium handling by cardiac sarcoplasmic reticulum.

Jones LR, Besch HR Jr.

Tex Rep Biol Med. 1979;39:19-35.PMID: 162246 [PubMed - indexed for MEDLINE]Related articles

Gel electrophoretic and density gradient analysis of the (K+ + Ca2+)-ATPase and the (Na+ + K+)-ATPase activities of cardiac membrane vesicles.

Jones LR, Phan SH, Besch HR Jr.

Biochim Biophys Acta. 1978 Dec 19;514(2):294-309. No abstract available. PMID: 216388 [PubMed - indexed for MEDLINE]Related articles

The positive inotropic effect of digitoxin: independence from sodium accumulation.

Besch HR Jr, Watanabe AM.

J Pharmacol Exp Ther. 1978 Dec;207(3):958-65. No abstract available. PMID: 731442 [PubMed - indexed for MEDLINE]Related articles

Ouabain sensitivity of the Na+, K+-ATPase activity from single bovine cardiac Purkinje fiber and adjacent papillary muscle.

Palfi FJ, Besch HR Jr, Watanabe AM.

J Mol Cell Cardiol. 1978 Dec;10(12):1149-55. No abstract available. PMID: 218023 [PubMed - indexed for MEDLINE]Related articles

Muscarinic cholinergic receptor modulation of beta-adrenergic receptor affinity for catecholamines.

Watanabe AM, McConnaughey MM, Strawbridge RA, Fleming JW, Jones LR, Besch HR Jr.

J Biol Chem. 1978 Jul 25;253(14):4833-6.PMID: 209018 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of l-dopa on sympathetic nerve activity and blood pressure in the spontaneously hypertensive rat.

Judy WV, Watanabe AM, Henry DP, Besch HR Jr, Aprison B.

Circ Res. 1978 Jul;43(1):24-8.PMID: 657456 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of microtubules in granulocyte adherence.

Boxer LA, Allen JM, Watanabe AM, Besch HR Jr, Baehner RL.

Blood. 1978 Jun;51(6):1045-50.PMID: 206298 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the calcium pump of cardiac sarcoplasmic reticulum. Interactive roles of potassium and ATP on the phosphoprotein intermediate of the (K+,Ca2+)-ATPase.

Jones LR, Besch HR Jr, Watanabe AM.

J Biol Chem. 1978 Mar 10;253(5):1643-53. No abstract available. PMID: 146716 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct effects of the monovalent cation ionophores monensin and nigericin on myocardium.

Sutko JL, Besch HR Jr, Bailey JC, Zimmerman G, Watanabe AM.

J Pharmacol Exp Ther. 1977 Dec;203(3):685-700. No abstract available. PMID: 925964 [PubMed - indexed for MEDLINE]Related articles

Parallel unmasking of latent adenylate cyclase and (Na+,K+)-ATPase activities in cardiac sarcolemmal vesicles. A new use of the channel-forming ionophore Alamethicin.

Besch HR Jr, Jones LR, Fleming JW, Watanabe AM.

J Biol Chem. 1977 Nov 25;252(22):7905-8. No abstract available. PMID: 144131 [PubMed - indexed for MEDLINE]Related articlesFree article

Binding and effect of tritiated quinidine on cardiac subcellular enzyme systems: sarcomplasmic reticulum vesicles, mitochondria and Na+, K+-adenosine triphosphatase.

Besch HR Jr, Watanabe AM.

J Pharmacol Exp Ther. 1977 Aug;202(2):354-64.PMID: 142144 [PubMed - indexed for MEDLINE]Related articles

alpha-Adrenergic reduction of cyclic adenosine monophosphate concentrations in rat myocardium.

Watanabe AM, Hathaway DR, Besch HR Jr, Farmer BB, Harris RA.

Circ Res. 1977 Jun;40(6):596-602.PMID: 15738 [PubMed - indexed for MEDLINE]Related articlesFree article