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Apoptotic, Regenerative, And Immune-Related Signaling in Human Islets from Type 2 Diabetes Individuals.

Nyblom HK, Bugliani M, Fung E, Boggi U, Zubarev R, Marchetti P, Bergsten P.

J Proteome Res. 2009 Nov 11. [Epub ahead of print]PMID: 19852514 [PubMed - as supplied by publisher]Related articles

Islet protein profiling.

Bergsten P.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:97-117.PMID: 19817793 [PubMed - in process]Related articles

How to set up an effective national primary angioplasty network: lessons learned from five European countries.

Knot J, Widimsky P, Wijns W, Stenestrand U, Kristensen SD, Van' T Hof A, Weidinger F, Janzon M, Nörgaard BL, Soerensen JT, van de Wetering H, Thygesen K, Bergsten PA, Digerfeldt C, Potgieter A, Tomer N, Fajadet J.

EuroIntervention. 2009 Aug;5(3):299, 301-309.PMID: 19736153 [PubMed - indexed for MEDLINE]Related articles

Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion.

Sol ER, Hovsepyan M, Bergsten P.

Proteome Sci. 2009 Jul 16;7:24.PMID: 19607692 [PubMed - in process]Related articlesFree article

Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells.

Sol EM, Sundsten T, Bergsten P.

Lipids Health Dis. 2009 Feb 5;8:3.PMID: 19196457 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms.

Hult M, Ortsäter H, Schuster G, Graedler F, Beckers J, Adamski J, Ploner A, Jörnvall H, Bergsten P, Oppermann U.

Mol Cell Endocrinol. 2009 Mar 25;301(1-2):109-16. Epub 2008 Oct 15.PMID: 18984029 [PubMed - indexed for MEDLINE]Related articles

Glucolipotoxicity in INS-1E cells is counteracted by carnitine palmitoyltransferase 1 over-expression.

Sol EM, Sargsyan E, Akusjärvi G, Bergsten P.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):517-21. Epub 2008 Aug 13.PMID: 18706397 [PubMed - indexed for MEDLINE]Related articles

Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells.

Sargsyan E, Ortsäter H, Thorn K, Bergsten P.

J Endocrinol. 2008 Oct;199(1):41-50. Epub 2008 Jul 21.PMID: 18644846 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase agonist dose dependently improves function and reduces apoptosis in glucotoxic beta-cells without changing triglyceride levels.

Nyblom HK, Sargsyan E, Bergsten P.

J Mol Endocrinol. 2008 Sep;41(3):187-94. Epub 2008 Jun 25.PMID: 18579684 [PubMed - indexed for MEDLINE]Related articlesFree article

Observers for Takagi-Sugeno fuzzy systems.

Bergsten P, Palm R, Driankov D.

IEEE Trans Syst Man Cybern B Cybern. 2002;32(1):114-21.PMID: 18238110 [PubMed - in process]Related articles

Serum protein patterns in newly diagnosed type 2 diabetes mellitus--influence of diabetic environment and family history of diabetes.

Sundsten T, Ostenson CG, Bergsten P.

Diabetes Metab Res Rev. 2008 Feb;24(2):148-54.PMID: 17968970 [PubMed - indexed for MEDLINE]Related articles

Plasma proteome changes in subjects with Type 2 diabetes mellitus with a low or high early insulin response.

Sundsten T, Zethelius B, Berne C, Bergsten P.

Clin Sci (Lond). 2008 Apr;114(7):499-507.PMID: 17961122 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids.

Nyblom HK, Nord LI, Andersson R, Kenne L, Bergsten P.

NMR Biomed. 2008 May;21(4):357-65.PMID: 17691080 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the SELDI-TOF MS technique for protein profiling of pancreatic islets exposed to glucose and oleate.

Ortsäter H, Sundsten T, Lin JM, Bergsten P.

Proteomics. 2007 Sep;7(17):3105-15.PMID: 17661320 [PubMed - indexed for MEDLINE]Related articles

Protein profiling of pancreatic islets.

Ortsäter H, Bergsten P.

Expert Rev Proteomics. 2006 Dec;3(6):665-75. Review.PMID: 17181479 [PubMed - indexed for MEDLINE]Related articles

The use of proteomics in identifying differentially expressed serum proteins in humans with type 2 diabetes.

Sundsten T, Eberhardson M, Göransson M, Bergsten P.

Proteome Sci. 2006 Dec 12;4:22.PMID: 17163994 [PubMed]Related articlesFree article

Mitochondrial protein patterns correlating with impaired insulin secretion from INS-1E cells exposed to elevated glucose concentrations.

Nyblom HK, Thorn K, Ahmed M, Bergsten P.

Proteomics. 2006 Oct;6(19):5193-8.PMID: 16941568 [PubMed - indexed for MEDLINE]Related articles

Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets.

Hernández-Fisac I, Fernández-Pascual S, Ortsäter H, Pizarro-Delgado J, Martín del Río R, Bergsten P, Tamarit-Rodriguez J.

Biochem J. 2006 Nov 15;400(1):81-9.PMID: 16819942 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.

Ahmed M, Forsberg J, Bergsten P.

J Proteome Res. 2005 May-Jun;4(3):931-40.PMID: 15952740 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced changes of multiple mouse islet proteins analysed by two-dimensional gel electrophoresis and mass spectrometry.

Ahmed M, Bergsten P.

Diabetologia. 2005 Mar;48(3):477-85. Epub 2005 Feb 24.PMID: 15729580 [PubMed - indexed for MEDLINE]Related articles

Regulation of 11beta-hydroxysteroid dehydrogenase type 1 and glucose-stimulated insulin secretion in pancreatic islets of Langerhans.

Ortsäter H, Alberts P, Warpman U, Engblom LO, Abrahmsén L, Bergsten P.

Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):359-66.PMID: 15586384 [PubMed - indexed for MEDLINE]Related articles

Microdialysis measurements demonstrate a shift to nonoxidative glucose metabolism in rat pancreatic islets transplanted beneath the renal capsule.

Carlsson PO, Kiuru A, Nordin A, Olsson R, Lin JM, Bergsten P, Hillered L, Andersson A, Jansson L.

Surgery. 2002 Sep;132(3):487-94.PMID: 12324763 [PubMed - indexed for MEDLINE]Related articles

Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion.

Ortsäter H, Liss P, Akerman KE, Bergsten P.

Pflugers Arch. 2002 Jul;444(4):506-12. Epub 2002 Jun 8.PMID: 12136270 [PubMed - indexed for MEDLINE]Related articles

Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes.

Lin JM, Fabregat ME, Gomis R, Bergsten P.

Diabetes. 2002 Apr;51(4):988-93.PMID: 11916916 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary in vivo oscillations of metabolism in the pancreas.

Bergsten P, Westerlund J, Liss P, Carlsson PO.

Diabetes. 2002 Mar;51(3):699-703.PMID: 11872669 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations.

Bergsten P.

Diabetes. 2002 Feb;51 Suppl 1:S171-6. Review.PMID: 11815477 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent promotion of insulin release from mouse pancreatic islets by the insulin-mimetic compound L-783,281.

Westerlund J, Wolf BA, Bergsten P.

Diabetes. 2002 Feb;51 Suppl 1:S50-2.PMID: 11815458 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats.

Lin JM, Ortsäter H, Fakhrai-Rad H, Galli J, Luthman H, Bergsten P.

Diabetes. 2001 Dec;50(12):2737-43.PMID: 11723056 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose metabolism and pulsatile insulin release from isolated islets.

Westerlund J, Bergsten P.

Diabetes. 2001 Aug;50(8):1785-90.PMID: 11473039 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway.

Westerlund J, Ortsäter H, Palm F, Sundsten T, Bergsten P.

Eur J Endocrinol. 2001 Jun;144(6):667-75.PMID: 11375802 [PubMed - indexed for MEDLINE]Related articlesFree article

Amplitude modulation of pulsatile insulin secretion by intrapancreatic ganglion neurons.

Sha L, Westerlund J, Szurszewski JH, Bergsten P.

Diabetes. 2001 Jan;50(1):51-5.PMID: 11147794 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling underlying pulsatile insulin secretion.

Gylfe E, Ahmed M, Bergsten P, Dansk H, Dyachok O, Eberhardson M, Grapengiesser E, Hellman B, Lin JM, Sundsten T, Tengholm A, Vieira E, Westerlund J.

Ups J Med Sci. 2000;105(2):35-51. Review. No abstract available. PMID: 11095104 [PubMed - indexed for MEDLINE]Related articles

Oscillations in oxygen tension and insulin release of individual pancreatic ob/ob mouse islets.

Ortsäter H, Liss P, Lund PE, Akerman KE, Bergsten P.

Diabetologia. 2000 Oct;43(10):1313-8.PMID: 11079751 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of impaired pulsatile insulin release.

Bergsten P.

Diabetes Metab Res Rev. 2000 May-Jun;16(3):179-91. Review.PMID: 10867718 [PubMed - indexed for MEDLINE]Related articles

Dynamic measurements of oxygen tension in islets of Langerhans.

Ortsäter H, Liss P, Lund PE, Akerman KE, Bergsten P.

Adv Exp Med Biol. 1999;471:367-72. No abstract available. PMID: 10659168 [PubMed - indexed for MEDLINE]Related articles

Preserved pulsatile insulin release from prediabetic mouse islets.

Lin JM, Sternesjö J, Sandler S, Bergsten P.

Endocrinology. 1999 Sep;140(9):3999-4004.PMID: 10465269 [PubMed - indexed for MEDLINE]Related articlesFree article

Appearance of glucose-induced insulin release in fetal rat beta-cells.

Bergsten P, Aoyagi K, Persson E, Eriksson UJ, Hellerström C.

J Endocrinol. 1998 Jul;158(1):115-20.PMID: 9713332 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced pulsatile insulin release from single islets at stable and oscillatory cytoplasmic Ca2+.

Bergsten P.

Am J Physiol. 1998 May;274(5 Pt 1):E796-800.PMID: 9612236 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin release: role of cytoplasmic Ca2+ oscillations.

Bergsten P, Lin J, Westerlund J.

Diabetes Metab. 1998 Feb;24(1):41-5. Review.PMID: 9534008 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.

Westerlund J, Gylfe E, Bergsten P.

J Clin Invest. 1997 Nov 15;100(10):2547-51.PMID: 9366569 [PubMed - indexed for MEDLINE]Related articlesFree article

Oscillatory signaling and insulin release in human pancreatic beta-cells exposed to strontium.

Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Berts A, Liu YJ, Tengholm A, Westerlund J.

Endocrinology. 1997 Aug;138(8):3161-5.PMID: 9231763 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16.

Aoyagi K, Bergsten P, Eriksson UJ, Ebendal T, Hellerström C.

Biol Neonate. 1997;71(1):60-8.PMID: 8996659 [PubMed - indexed for MEDLINE]Related articles

Pulsatile insulin release from mouse islets occurs in the absence of stimulated entry of Ca2+.

Westerlund J, Hellman B, Bergsten P.

J Clin Invest. 1996 Apr 15;97(8):1860-3.PMID: 8621769 [PubMed - indexed for MEDLINE]Related articlesFree article

Ascorbic acid transport and distribution in human B lymphocytes.

Bergsten P, Yu R, Kehrl J, Levine M.

Arch Biochem Biophys. 1995 Feb 20;317(1):208-14.PMID: 7872786 [PubMed - indexed for MEDLINE]Related articles

Slow and fast oscillations of cytoplasmic Ca2+ in pancreatic islets correspond to pulsatile insulin release.

Bergsten P.

Am J Physiol. 1995 Feb;268(2 Pt 1):E282-7.PMID: 7864105 [PubMed - indexed for MEDLINE]Related articles

Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells.

Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Lund PE, Berts A, Tengholm A, Pipeleers DG, Ling Z.

Diabetologia. 1994 Sep;37 Suppl 2:S11-20.PMID: 7821725 [PubMed - indexed for MEDLINE]Related articles

Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets.

Bergsten P, Grapengiesser E, Gylfe E, Tengholm A, Hellman B.

J Biol Chem. 1994 Mar 25;269(12):8749-53.PMID: 8132606 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of Ca2+ in the release of pancreatic islet hormones.

Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Lund PE, Berts A, Dryselius S, Tengholm A, Liu YJ, Eberhardson M, et al.

Diabete Metab. 1994 Mar-Apr;20(2):123-31.PMID: 7805949 [PubMed - indexed for MEDLINE]Related articles

Ascorbic acid and insulin secretion in pancreatic islets.

Bergsten P, Moura AS, Atwater I, Levine M.

J Biol Chem. 1994 Jan 14;269(2):1041-5.PMID: 8288558 [PubMed - indexed for MEDLINE]Related articlesFree article

Ascorbic acid accumulation and transport in human fibroblasts.

Welch RW, Bergsten P, Butler JD, Levine M.

Biochem J. 1993 Sep 1;294 ( Pt 2):505-10.PMID: 8373364 [PubMed - indexed for MEDLINE]Related articlesFree article