PubMed

Liver fat and lipid oxidation in humans.

Kotronen A, Seppälä-Lindroos A, Vehkavaara S, Bergholm R, Frayn KN, Fielding BA, Yki-Järvinen H.

Liver Int. 2009 Oct;29(9):1439-46. Epub 2009 Jul 7.PMID: 19602132 [PubMed - indexed for MEDLINE]Related articles

Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.

Kotronen A, Peltonen M, Hakkarainen A, Sevastianova K, Bergholm R, Johansson LM, Lundbom N, Rissanen A, Ridderstråle M, Groop L, Orho-Melander M, Yki-Järvinen H.

Gastroenterology. 2009 Sep;137(3):865-72. Epub 2009 Jun 12.PMID: 19524579 [PubMed - indexed for MEDLINE]Related articles

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.

Kotronen A, Johansson LE, Johansson LM, Roos C, Westerbacka J, Hamsten A, Bergholm R, Arkkila P, Arola J, Kiviluoto T, Fisher RM, Ehrenborg E, Orho-Melander M, Ridderstråle M, Groop L, Yki-Järvinen H.

Diabetologia. 2009 Jun;52(6):1056-60. Epub 2009 Feb 18.PMID: 19224197 [PubMed - indexed for MEDLINE]Related articles

Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations.

Kotronen A, Velagapudi VR, Yetukuri L, Westerbacka J, Bergholm R, Ekroos K, Makkonen J, Taskinen MR, Oresic M, Yki-Järvinen H.

Diabetologia. 2009 Apr;52(4):684-90. Epub 2009 Feb 13.PMID: 19214471 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

Kotronen A, Yki-Järvinen H, Aminoff A, Bergholm R, Pietiläinen KH, Westerbacka J, Talmud PJ, Humphries SE, Hamsten A, Isomaa B, Groop L, Orho-Melander M, Ehrenborg E, Fisher RM.

Eur J Endocrinol. 2009 Apr;160(4):593-602. Epub 2009 Feb 10.PMID: 19208777 [PubMed - indexed for MEDLINE]Related articles

Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients.

Tikka S, Mykkänen K, Ruchoux MM, Bergholm R, Junna M, Pöyhönen M, Yki-Järvinen H, Joutel A, Viitanen M, Baumann M, Kalimo H.

Brain. 2009 Apr;132(Pt 4):933-9. Epub 2009 Jan 27.PMID: 19174371 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome.

Kotronen A, Seppälä-Lindroos A, Bergholm R, Yki-Järvinen H.

Diabetologia. 2008 Jan;51(1):130-8. Epub 2007 Nov 16.PMID: 18008059 [PubMed - indexed for MEDLINE]Related articles

Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects.

Kotronen A, Juurinen L, Hakkarainen A, Westerbacka J, Cornér A, Bergholm R, Yki-Järvinen H.

Diabetes Care. 2008 Jan;31(1):165-9. Epub 2007 Oct 12.PMID: 17934148 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of liver fat on insulin clearance.

Kotronen A, Vehkavaara S, Seppälä-Lindroos A, Bergholm R, Yki-Järvinen H.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1709-15. Epub 2007 Sep 25.PMID: 17895288 [PubMed - indexed for MEDLINE]Related articlesFree article

Exploring the lipoprotein composition using Bayesian regression on serum lipidomic profiles.

Sysi-Aho M, Vehtari A, Velagapudi VR, Westerbacka J, Yetukuri L, Bergholm R, Taskinen MR, Yki-Järvinen H, Oresic M.

Bioinformatics. 2007 Jul 1;23(13):i519-28.PMID: 17646339 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

Kolak M, Westerbacka J, Velagapudi VR, Wågsäter D, Yetukuri L, Makkonen J, Rissanen A, Häkkinen AM, Lindell M, Bergholm R, Hamsten A, Eriksson P, Fisher RM, Oresic M, Yki-Järvinen H.

Diabetes. 2007 Aug;56(8):1960-8. Epub 2007 Jul 9.PMID: 17620421 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver fat in the metabolic syndrome.

Kotronen A, Westerbacka J, Bergholm R, Pietiläinen KH, Yki-Järvinen H.

J Clin Endocrinol Metab. 2007 Sep;92(9):3490-7. Epub 2007 Jun 26.PMID: 17595248 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of acquired obesity on endothelial function in monozygotic twins.

Pietiläinen KH, Bergholm R, Rissanen A, Kaprio J, Häkkinen AM, Sattar N, Yki-Järvinen H.

Obesity (Silver Spring). 2006 May;14(5):826-37.PMID: 16855192 [PubMed - indexed for MEDLINE]Related articles

Glycodelin responses to hyperinsulinaemic clamp vary according to basal serum glycodelin concentration.

Seppälä M, Mandelin E, Koistinen R, Bergholm R, Tiikkainen M, Yki-Järvinen H.

Clin Endocrinol (Oxf). 2005 May;62(5):611-5.PMID: 15853834 [PubMed - indexed for MEDLINE]Related articles

Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women.

Tiikkainen M, Bergholm R, Rissanen A, Aro A, Salminen I, Tamminen M, Teramo K, Yki-Järvinen H.

Am J Clin Nutr. 2004 Jan;79(1):22-30.PMID: 14684393 [PubMed - indexed for MEDLINE]Related articlesFree article

Glargine and regular human insulin similarly acutely enhance endothelium-dependent vasodilatation in normal subjects.

Westerbacka J, Bergholm R, Tiikkainen M, Yki-Järvinen H.

Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):320-4. Epub 2003 Dec 4.PMID: 14656737 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased inflammatory activity parallels increased basal nitric oxide production and blunted response to nitric oxide in vivo in rheumatoid arthritis.

Yki-Järvinen H, Bergholm R, Leirisalo-Repo M.

Ann Rheum Dis. 2003 Jul;62(7):630-4.PMID: 12810424 [PubMed - indexed for MEDLINE]Related articlesFree article

Lowering of LDL cholesterol rather than moderate weight loss improves endothelium-dependent vasodilatation in obese women with previous gestational diabetes.

Bergholm R, Tiikkainen M, Vehkavaara S, Tamminen M, Teramo K, Rissanen A, Yki-Järvinen H.

Diabetes Care. 2003 Jun;26(6):1667-72.PMID: 12766091 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content.

Tiikkainen M, Bergholm R, Vehkavaara S, Rissanen A, Häkkinen AM, Tamminen M, Teramo K, Yki-Järvinen H.

Diabetes. 2003 Mar;52(3):701-7.PMID: 12606511 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis.

Bergholm R, Leirisalo-Repo M, Vehkavaara S, Mäkimattila S, Taskinen MR, Yki-Järvinen H.

Arterioscler Thromb Vasc Biol. 2002 Oct 1;22(10):1637-41.PMID: 12377742 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes.

Tiikkainen M, Tamminen M, Häkkinen AM, Bergholm R, Vehkavaara S, Halavaara J, Teramo K, Rissanen A, Yki-Järvinen H.

Obes Res. 2002 Sep;10(9):859-67.PMID: 12226133 [PubMed - indexed for MEDLINE]Related articles

Insulin sensitivity regulates autonomic control of heart rate variation independent of body weight in normal subjects.

Bergholm R, Westerbacka J, Vehkavaara S, Seppälä-Lindroos A, Goto T, Yki-Järvinen H.

J Clin Endocrinol Metab. 2001 Mar;86(3):1403-9.PMID: 11238539 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of oral and transdermal estrogen replacement therapy on endothelial function in postmenopausal women.

Vehkavaara S, Hakala-Ala-Pietilä T, Virkamäki A, Bergholm R, Ehnholm C, Hovatta O, Taskinen MR, Yki-Järvinen H.

Circulation. 2000 Nov 28;102(22):2687-93. Erratum in: Circulation. 2005 Jul 26;112(4):e72. PMID: 11094033 [PubMed - indexed for MEDLINE]Related articlesFree article

Predictors of abnormal cardiovascular autonomic function measured by frequence domain analysis of heart rate variability and conventional tests in patients with type 1 diabetes.

Mäkimattila S, Schlenzka A, Mäntysaari M, Bergholm R, Summanen P, Saar P, Erkkilä H, Yki-Järvinen H.

Diabetes Care. 2000 Nov;23(11):1686-93.PMID: 11092293 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoantibodies against oxidized LDL and endothelium-dependent vasodilation in insulin-dependent diabetes mellitus.

Mäkimattila S, Luoma JS, Ylä-Herttuala S, Bergholm R, Utriainen T, Virkamäki A, Mäntysaari M, Summanen P, Yki-Järvinen H.

Atherosclerosis. 1999 Nov 1;147(1):115-22.PMID: 10525132 [PubMed - indexed for MEDLINE]Related articles

Intense physical training decreases circulating antioxidants and endothelium-dependent vasodilatation in vivo.

Bergholm R, Mäkimattila S, Valkonen M, Liu ML, Lahdenperä S, Taskinen MR, Sovijärvi A, Malmberg P, Yki-Järvinen H.

Atherosclerosis. 1999 Aug;145(2):341-9.PMID: 10488962 [PubMed - indexed for MEDLINE]Related articles

Impaired endothelium-dependent vasodilation in type 2 diabetes. Relation to LDL size, oxidized LDL, and antioxidants.

Mäkimattila S, Liu ML, Vakkilainen J, Schlenzka A, Lahdenperä S, Syvänne M, Mäntysaari M, Summanen P, Bergholm R, Taskinen MR, Yki-Järvinen H.

Diabetes Care. 1999 Jun;22(6):973-81.PMID: 10372251 [PubMed - indexed for MEDLINE]Related articlesFree article

A marathon run increases the susceptibility of LDL to oxidation in vitro and modifies plasma antioxidants.

Liu ML, Bergholm R, Mäkimattila S, Lahdenperä S, Valkonen M, Hilden H, Yki-Järvinen H, Taskinen MR.

Am J Physiol. 1999 Jun;276(6 Pt 1):E1083-91.PMID: 10362621 [PubMed - indexed for MEDLINE]Related articlesFree article

Marked resistance of the ability of insulin to decrease arterial stiffness characterizes human obesity.

Westerbacka J, Vehkavaara S, Bergholm R, Wilkinson I, Cockcroft J, Yki-Järvinen H.

Diabetes. 1999 Apr;48(4):821-7.PMID: 10102699 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation between insulin sensitivity of glucose uptake and endothelial function in normal subjects.

Utriainen T, Mäkimattila S, Virkamäki A, Bergholm R, Yki-Järvinen H.

Diabetologia. 1996 Dec;39(12):1477-82.PMID: 8960829 [PubMed - indexed for MEDLINE]Related articles