PubMed

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose stimulated insulin release.

Fornoni A, Jeon J, Santos JV, Cobianchi L, Jauregui A, Inverardi L, Mandic SA, Bark C, Johnson K, McNamara G, Pileggi A, Molano RD, Reiser J, Tryggvason K, Kerjaschki D, Berggren PO, Mundel P, Ricordi C.

Diabetes. 2009 Oct 28. [Epub ahead of print]PMID: 19833886 [PubMed - as supplied by publisher]Related articles

Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats.

Holmberg R, Klitz W, Blixt M, Berggren PO, Juntti-Berggren L, Niklasson B.

Microbiol Immunol. 2009 Oct;53(10):567-72.PMID: 19780970 [PubMed - in process]Related articles

Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death.

Zaitseva II, Hultcrantz M, Sharoyko V, Flodström-Tullberg M, Zaitsev SV, Berggren PO.

Cell Mol Life Sci. 2009 Dec;66(23):3787-95.PMID: 19763396 [PubMed - in process]Related articles

Inositol pyrophosphates: structure, enzymology and function.

Barker CJ, Illies C, Gaboardi GC, Berggren PO.

Cell Mol Life Sci. 2009 Aug 28. [Epub ahead of print]PMID: 19714294 [PubMed - as supplied by publisher]Related articles

Diphosphoinositol pentakisphosphate as a novel mediator of insulin exocytosis.

Barker CJ, Illies C, Fiume R, Gaboardi GC, Yu J, Berggren PO.

Adv Enzyme Regul. 2009 Jan 19. [Epub ahead of print] No abstract available. PMID: 19640416 [PubMed - as supplied by publisher]Related articles

Diphosphoinositol pentakisphosphate as a novel mediator of insulin exocytosis.

Barker CJ, Illies C, Fiume R, Gaboardi GC, Yu J, Berggren PO.

Adv Enzyme Regul. 2009;49(1):168-73. Review. No abstract available. PMID: 19534030 [PubMed - indexed for MEDLINE]Related articles

Beneficial role of pancreatic microenvironment for angiogenesis in transplanted pancreatic islets.

Lau J, Kampf C, Mattsson G, Nyqvist D, Köhler M, Berggren PO, Carlsson PO.

Cell Transplant. 2009;18(1):23-30.PMID: 19476206 [PubMed - indexed for MEDLINE]Related articles

Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects.

Margolles-Clark E, Jacques-Silva MC, Ganesan L, Umland O, Kenyon NS, Ricordi C, Berggren PO, Buchwald P.

Biochem Pharmacol. 2009 Apr 1;77(7):1236-45.PMID: 19283894 [PubMed - indexed for MEDLINE]Related articles

An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function.

Johansson JU, Ericsson J, Janson J, Beraki S, Stanić D, Mandic SA, Wikström MA, Hökfelt T, Ogren SO, Rozell B, Berggren PO, Bark C.

PLoS Genet. 2008 Nov;4(11):e1000278. Epub 2008 Nov 28.PMID: 19043548 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of wireless 48-h (Bravo) versus traditional ambulatory 24-h esophageal pH monitoring.

Håkanson BS, Berggren P, Granqvist S, Ljungqvist O, Thorell A.

Scand J Gastroenterol. 2009;44(3):276-83.PMID: 19040176 [PubMed - indexed for MEDLINE]Related articles

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye.

Speier S, Nyqvist D, Köhler M, Caicedo A, Leibiger IB, Berggren PO.

Nat Protoc. 2008;3(8):1278-86.PMID: 18714296 [PubMed - indexed for MEDLINE]Related articles

Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation.

Paulsson JF, Schultz SW, Köhler M, Leibiger I, Berggren PO, Westermark GT.

Exp Diabetes Res. 2008;2008:865850.PMID: 18566681 [PubMed - indexed for MEDLINE]Related articlesFree article

Parachuting from fixed objects: descriptive study of 106 fatal events in BASE jumping 1981-2006.

Westman A, Rosén M, Berggren P, Björnstig U.

Br J Sports Med. 2008 Jun;42(6):431-6. Epub 2008 Jun 3.PMID: 18523039 [PubMed - indexed for MEDLINE]Related articles

Glutamate is a positive autocrine signal for glucagon release.

Cabrera O, Jacques-Silva MC, Speier S, Yang SN, Köhler M, Fachado A, Vieira E, Zierath JR, Kibbey R, Berman DM, Kenyon NS, Ricordi C, Caicedo A, Berggren PO.

Cell Metab. 2008 Jun;7(6):545-54.PMID: 18522835 [PubMed - indexed for MEDLINE]Related articles

Insulin signaling in the pancreatic beta-cell.

Leibiger IB, Leibiger B, Berggren PO.

Annu Rev Nutr. 2008;28:233-51. Review.PMID: 18481923 [PubMed - indexed for MEDLINE]Related articles

Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function.

Bertolino P, Holmberg R, Reissmann E, Andersson O, Berggren PO, Ibáñez CF.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7246-51. Epub 2008 May 14.PMID: 18480258 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteins in the insulin-secreting cell line MIN6 bind the imidazoline compound BL11282.

Shafqat J, Ishrat M, Jägerbrink T, Sillard R, Mäeorg U, Efendic S, Berggren PO, Zaitsev SV, Jörnvall H.

FEBS Lett. 2008 May 14;582(11):1613-7. Epub 2008 Apr 15.PMID: 18420036 [PubMed - indexed for MEDLINE]Related articles

Automated, high-throughput assays for evaluation of human pancreatic islet function.

Cabrera O, Jacques-Silva MC, Berman DM, Fachado A, Echeverri F, Poo R, Khan A, Kenyon NS, Ricordi C, Berggren PO, Caicedo A.

Cell Transplant. 2008;16(10):1039-48.PMID: 18351020 [PubMed - indexed for MEDLINE]Related articles

Professor Rolf Luft, 1914--2007.

Berggren PO, Brismar K.

Diabetologia. 2008 May;51(5):697-9. No abstract available. PMID: 18327565 [PubMed - indexed for MEDLINE]Related articlesFree article

Noninvasive in vivo imaging of pancreatic islet cell biology.

Speier S, Nyqvist D, Cabrera O, Yu J, Molano RD, Pileggi A, Moede T, Köhler M, Wilbertz J, Leibiger B, Ricordi C, Leibiger IB, Caicedo A, Berggren PO.

Nat Med. 2008 May;14(5):574-8. Epub 2008 Mar 7.PMID: 18327249 [PubMed - indexed for MEDLINE]Related articles

The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase.

Zaitseva II, Størling J, Mandrup-Poulsen T, Berggren PO, Zaitsev SV.

Cell Mol Life Sci. 2008 Apr;65(7-8):1248-55.PMID: 18278435 [PubMed - indexed for MEDLINE]Related articles

A key role for phosphorylated inositol compounds in pancreatic beta-cell stimulus-secretion coupling.

Berggren PO, Barker CJ.

Adv Enzyme Regul. 2008;48:276-94. Epub 2008 Mar 14. Review. No abstract available. PMID: 18194673 [PubMed - indexed for MEDLINE]Related articles

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells.

Illies C, Gromada J, Fiume R, Leibiger B, Yu J, Juhl K, Yang SN, Barma DK, Falck JR, Saiardi A, Barker CJ, Berggren PO.

Science. 2007 Nov 23;318(5854):1299-302.PMID: 18033884 [PubMed - indexed for MEDLINE]Related articlesFree article

Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion.

Sharoyko VV, Zaitseva II, Leibiger B, Efendić S, Berggren PO, Zaitsev SV.

Cell Mol Life Sci. 2007 Nov;64(22):2985-93.PMID: 17922229 [PubMed - indexed for MEDLINE]Related articles

Distribution of intraportally implanted microspheres and fluorescent islets in mice.

von Seth E, Nyqvist D, Andersson A, Carlsson PO, Köhler M, Mattsson G, Nordin A, Berggren PO, Jansson L.

Cell Transplant. 2007;16(6):621-7.PMID: 17912953 [PubMed - indexed for MEDLINE]Related articles

Further Scrutiny of Scientific Whaling.

Brownell Jr RL, Tillman MF, di Sciara GN, Berggren P, Read AJ.

Science. 2000 Dec 1;290(5497):1696a. No abstract available. PMID: 17798206 [PubMed - as supplied by publisher]Related articles

Glucose recruits K(ATP) channels via non-insulin-containing dense-core granules.

Yang SN, Wenna ND, Yu J, Yang G, Qiu H, Yu L, Juntti-Berggren L, Köhler M, Berggren PO.

Cell Metab. 2007 Sep;6(3):217-28.PMID: 17767908 [PubMed - indexed for MEDLINE]Related articles

Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model.

Berman DM, Cabrera O, Kenyon NM, Miller J, Tam SH, Khandekar VS, Picha KM, Soderman AR, Jordan RE, Bugelski PJ, Horninger D, Lark M, Davis JE, Alejandro R, Berggren PO, Zimmerman M, O'Neil JJ, Ricordi C, Kenyon NS.

Transplantation. 2007 Aug 15;84(3):308-15.PMID: 17700154 [PubMed - indexed for MEDLINE]Related articles

3H-serotonin as a marker of oscillatory insulin secretion in clonal beta-cells (INS-1).

Deeney JT, Bränström R, Corkey BE, Larsson O, Berggren PO.

FEBS Lett. 2007 Aug 21;581(21):4080-4. Epub 2007 Jul 30.PMID: 17686476 [PubMed - indexed for MEDLINE]Related articles

An autocrine insulin feedback loop maintains pancreatic beta-cell 3-phosphorylated inositol lipids.

Yu J, Berggren PO, Barker CJ.

Mol Endocrinol. 2007 Nov;21(11):2775-84. Epub 2007 Jul 24.PMID: 17652185 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetic serum interferes with pancreatic beta-cell Ca2+-handling.

Dekki N, Nilsson R, Norgren S, Rössner SM, Appelskog I, Marcus C, Simell O, Pugliese A, Alejandro R, Ricordi C, Berggren PO, Juntti-Berggren L.

Biosci Rep. 2007 Dec;27(6):321-6.PMID: 17597394 [PubMed - indexed for MEDLINE]Related articles

Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion.

Richard AM, Webb DL, Goodman JM, Schultz V, Flanagan JN, Getty-Kaushik L, Deeney JT, Yaney GC, Dunaway GA, Berggren PO, Tornheim K.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E794-801. Epub 2007 Jun 26.PMID: 17595219 [PubMed - indexed for MEDLINE]Related articlesFree article

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.

Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.

Diabetologia. 2007 Aug;50(8):1670-7. Epub 2007 May 24.PMID: 17522836 [PubMed - indexed for MEDLINE]Related articles

Differential protein expression in pancreatic islets after treatment with an imidazoline compound.

Jägerbrink T, Lexander H, Palmberg C, Shafqat J, Sharoyko V, Berggren PO, Efendic S, Zaitsev S, Jörnvall H.

Cell Mol Life Sci. 2007 May;64(10):1310-6.PMID: 17458497 [PubMed - indexed for MEDLINE]Related articles

The BioBreeding rat diabetes model is infected with Ljungan virus.

Niklasson B, Hultman T, Kallies R, Niedrig M, Nilsson R, Berggren PO, Juntti-Berggren L, Efendic S, Lernmark A, Klitz W.

Diabetologia. 2007 Jul;50(7):1559-60. Epub 2007 Apr 4. No abstract available. Erratum in: Diabetologia. 2007 Oct;50(10):2227. PMID: 17406852 [PubMed - indexed for MEDLINE]Related articles

Implantation site-dependent dysfunction of transplanted pancreatic islets.

Lau J, Mattsson G, Carlsson C, Nyqvist D, Köhler M, Berggren PO, Jansson L, Carlsson PO.

Diabetes. 2007 Jun;56(6):1544-50. Epub 2007 Mar 30.PMID: 17400931 [PubMed - indexed for MEDLINE]Related articlesFree article

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

Zhang Q, Bengtsson M, Partridge C, Salehi A, Braun M, Cox R, Eliasson L, Johnson PR, Renström E, Schneider T, Berggren PO, Göpel S, Ashcroft FM, Rorsman P.

Nat Cell Biol. 2007 Apr;9(4):453-60. Epub 2007 Mar 18.PMID: 17369816 [PubMed - indexed for MEDLINE]Related articles

Selective gene activation by spatial segregation of insulin receptor B signaling.

Uhles S, Moede T, Leibiger B, Berggren PO, Leibiger IB.

FASEB J. 2007 May;21(7):1609-21. Epub 2007 Jan 30.PMID: 17264162 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, Hakonen E, Juntti-Berggren L, Berggren PO, Otonkoski T.

Diabetes. 2006 Dec;55(12):3299-308.PMID: 17130473 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling.

Henriksson M, Johansson J, Moede T, Leibiger I, Shafqat J, Berggren PO, Jörnvall H.

Cell Mol Life Sci. 2006 Dec;63(24):3055-60.PMID: 17115117 [PubMed - indexed for MEDLINE]Related articles

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.

Zaitseva II, Sharoyko V, Størling J, Efendic S, Guerin C, Mandrup-Poulsen T, Nicotera P, Berggren PO, Zaitsev SV.

Biochem Biophys Res Commun. 2006 Sep 8;347(4):1121-8. Epub 2006 Jul 14.PMID: 16870144 [PubMed - indexed for MEDLINE]Related articles

The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology.

Yang SN, Berggren PO.

Endocr Rev. 2006 Oct;27(6):621-76. Epub 2006 Jul 25. Review.PMID: 16868246 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel aspects on signal-transduction in the pancreatic beta-cell.

Berggren PO, Leibiger IB.

Nutr Metab Cardiovasc Dis. 2006 Mar;16 Suppl 1:S7-10. Epub 2006 Feb 9. Review.PMID: 16530130 [PubMed - indexed for MEDLINE]Related articles

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis.

Zhang W, Lilja L, Mandic SA, Gromada J, Smidt K, Janson J, Takai Y, Bark C, Berggren PO, Meister B.

Diabetes. 2006 Mar;55(3):574-81.PMID: 16505218 [PubMed - indexed for MEDLINE]Related articlesFree article

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function.

Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2334-9. Epub 2006 Feb 6.PMID: 16461897 [PubMed - indexed for MEDLINE]Related articlesFree article

Sirt1: a metabolic master switch that modulates lifespan.

Leibiger IB, Berggren PO.

Nat Med. 2006 Jan;12(1):34-6; discussion 36. No abstract available. PMID: 16397557 [PubMed - indexed for MEDLINE]Related articles

Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling.

Refai E, Dekki N, Yang SN, Imreh G, Cabrera O, Yu L, Yang G, Norgren S, Rössner SM, Inverardi L, Ricordi C, Olivecrona G, Andersson M, Jörnvall H, Berggren PO, Juntti-Berggren L.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17020-5. Epub 2005 Nov 14.PMID: 16286652 [PubMed - indexed for MEDLINE]Related articlesFree article

Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic beta-cells.

Sharoyko VV, Zaitseva II, Varsanyi M, Portwood N, Leibiger B, Leibiger I, Berggren PO, Efendić S, Zaitsev SV.

Biochem Biophys Res Commun. 2005 Dec 23;338(3):1455-9. Epub 2005 Nov 2.PMID: 16277977 [PubMed - indexed for MEDLINE]Related articles

A SIRTain role in pancreatic beta cell function.

Leibiger IB, Berggren PO.

Cell Metab. 2005 Aug;2(2):80-2.PMID: 16098824 [PubMed - indexed for MEDLINE]Related articles

Pancreatic islet function in a transgenic mouse expressing fluorescent protein.

Nyqvist D, Mattsson G, Köhler M, Lev-Ram V, Andersson A, Carlsson PO, Nordin A, Berggren PO, Jansson L.

J Endocrinol. 2005 Aug;186(2):333-41.PMID: 16079259 [PubMed - indexed for MEDLINE]Related articlesFree article