PubMed

Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene.

Huang SC, Cho A, Norton S, Liu ES, Park J, Zhou A, Munagala ID, Ou AC, Yang G, Wickrema A, Tang TK, Benz EJ Jr.

Blood. 2009 Nov 5;114(19):4233-42. Epub 2009 Sep 3.PMID: 19729518 [PubMed - indexed for MEDLINE]Related articles

Commentary: troublesome words, linguistic precision, and medical oncology.

Bates SE, Benz EJ Jr.

Oncologist. 2009 Apr;14(4):445-7. Review. No abstract available. PMID: 19357227 [PubMed - indexed for MEDLINE]Related articles

Paroxysmal nocturnal hemoglobinuria (PNH): an historical perspective.

Benz EJ Jr.

Hematology Am Soc Hematol Educ Program. 2008:92. No abstract available. PMID: 19074064 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.

Zhou A, Ou AC, Cho A, Benz EJ Jr, Huang SC.

Mol Cell Biol. 2008 Oct;28(19):5924-36. Epub 2008 Jul 28.PMID: 18663000 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting the cell death-survival equation.

Benz EJ Jr, Nathan DG, Amaravadi RK, Danial NN.

Clin Cancer Res. 2007 Dec 15;13(24):7250-3. Review. No abstract available. PMID: 18094404 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of an integrated approach to cancer disparities: one cancer center's experience.

Emmons KM, Burns White K, Benz EJ.

Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2186-92. No abstract available. PMID: 18006905 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulated Fox-2 isoform expression mediates protein 4.1R splicing during erythroid differentiation.

Yang G, Huang SC, Wu JY, Benz EJ Jr.

Blood. 2008 Jan 1;111(1):392-401. Epub 2007 Aug 22.PMID: 17715393 [PubMed - indexed for MEDLINE]Related articlesFree article

2006 Association of American Physicians George M. Kober Medal. Introduction of David G. Nathan, MD.

Benz EJ.

J Clin Invest. 2007 Apr;117(4):1107-11. No abstract available. PMID: 17404624 [PubMed - indexed for MEDLINE]Related articlesFree article

Partnerships with patients.

Benz EJ Jr, Countryman GL.

Trustee. 2006 Oct;59(9):40, 56. No abstract available. PMID: 17058706 [PubMed - indexed for MEDLINE]Related articles

Restructuring the academic department of internal medicine.

Feldman AM, Benz EJ Jr.

Am J Med. 2005 Dec;118(12):1430-5. Review. No abstract available. PMID: 16378806 [PubMed - indexed for MEDLINE]Related articles

Mitotic regulation of protein 4.1R involves phosphorylation by cdc2 kinase.

Huang SC, Liu ES, Chan SH, Munagala ID, Cho HT, Jagadeeswaran R, Benz EJ Jr.

Mol Biol Cell. 2005 Jan;16(1):117-27. Epub 2004 Nov 3.PMID: 15525677 [PubMed - indexed for MEDLINE]Related articlesFree article

An erythroid differentiation-specific splicing switch in protein 4.1R mediated by the interaction of SF2/ASF with an exonic splicing enhancer.

Yang G, Huang SC, Wu JY, Benz EJ Jr.

Blood. 2005 Mar 1;105(5):2146-53. Epub 2004 Nov 2.PMID: 15522963 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotypes and phenotypes--another lesson from the hemoglobinopathies.

Benz EJ Jr.

N Engl J Med. 2004 Oct 7;351(15):1490-2. No abstract available. Erratum in: N Engl J Med. 2005 Feb 3;352(5):524. PMID: 15470211 [PubMed - indexed for MEDLINE]Related articles

Protein 4.1R, a microtubule-associated protein involved in microtubule aster assembly in mammalian mitotic extract.

Huang SC, Jagadeeswaran R, Liu ES, Benz EJ Jr.

J Biol Chem. 2004 Aug 13;279(33):34595-602. Epub 2004 Jun 7.PMID: 15184364 [PubMed - indexed for MEDLINE]Related articlesFree article

A splicing alteration of 4.1R pre-mRNA generates 2 protein isoforms with distinct assembly to spindle poles in mitotic cells.

Delhommeau F, Vasseur-Godbillon C, Leclerc P, Schischmanoff PO, Croisille L, Rince P, Morinière M, Benz EJ Jr, Tchernia G, Tamagnini G, Ribeiro L, Delaunay J, Baklouti F.

Blood. 2002 Oct 1;100(7):2629-36.PMID: 12239178 [PubMed - indexed for MEDLINE]Related articlesFree article

Comprehensive cancer centres and the war on cancer.

Nathan D, Benz EJ.

Nat Rev Cancer. 2001 Dec;1(3):240-5. Review.PMID: 11902579 [PubMed - indexed for MEDLINE]Related articles

Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation.

Deguillien M, Huang SC, Morinière M, Dreumont N, Benz EJ Jr, Baklouti F.

Blood. 2001 Dec 15;98(13):3809-16.PMID: 11739190 [PubMed - indexed for MEDLINE]Related articlesFree article

Reassignment of the EPB4.1 gene to 1p36 and assessment of its involvement in neuroblastomas.

Huang S, Lichtenauer UD, Pack S, Wang C, Kim AC, Lutchman M, Koch CA, Torres-Cruz J, Huang SC, Benz EJ Jr, Christiansen H, Dockhorn-Dworniczak B, Poremba C, Vortmeyer AO, Chishti AH, Zhuang Z.

Eur J Clin Invest. 2001 Oct;31(10):907-14.PMID: 11737230 [PubMed - indexed for MEDLINE]Related articles

The prototypical 4.1R-10-kDa domain and the 4.1g-10-kDa paralog mediate fodrin-actin complex formation.

Kontrogianni-Konstantopoulos A, Frye CS, Benz EJ Jr, Huang SC.

J Biol Chem. 2001 Jun 8;276(23):20679-87. Epub 2001 Mar 23.PMID: 11274145 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational regulation of Na-K-ATPase subunit mRNAs by glucocorticoids.

Devarajan P, Benz EJ Jr.

Am J Physiol Renal Physiol. 2000 Dec;279(6):F1132-8.PMID: 11097633 [PubMed - indexed for MEDLINE]Related articlesFree article

Edward J. Benz, Jr, MD.

Benz EJ.

J Investig Med. 2000 Nov;48(6):381-4. No abstract available. PMID: 11094857 [PubMed - indexed for MEDLINE]Related articles

A nonerythroid isoform of protein 4.1R interacts with components of the contractile apparatus in skeletal myofibers.

Kontrogianni-Konstantopoulos A, Huang SC, Benz EJ Jr.

Mol Biol Cell. 2000 Nov;11(11):3805-17.PMID: 11071908 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeleton.

Mattagajasingh SN, Huang SC, Hartenstein JS, Benz EJ Jr.

J Biol Chem. 2000 Sep 29;275(39):30573-85.PMID: 10874042 [PubMed - indexed for MEDLINE]Related articlesFree article

Clonal variation, autoimmunity, and neoplasia: an ecology lesson from paroxysmal nocturnal hemoglobinuria.

Benz EJ Jr.

Ann Intern Med. 1999 Sep 21;131(6):467-8. No abstract available. PMID: 10498565 [PubMed - indexed for MEDLINE]Related articlesFree article

A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein.

Mattagajasingh SN, Huang SC, Hartenstein JS, Snyder M, Marchesi VT, Benz EJ.

J Cell Biol. 1999 Apr 5;145(1):29-43.PMID: 10189366 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing academic internal medicine's investment in female faculty.

Benz EJ Jr, Clayton CP, Costa ST.

Am J Med. 1998 Dec;105(6):459-63. No abstract available. PMID: 9870829 [PubMed - indexed for MEDLINE]Related articles

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane.

Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low PS, Rouleau GA, Mohandas N, Chasis JA, Conboy JG, Gascard P, Takakuwa Y, Huang SC, Benz EJ Jr, Bretscher A, Fehon RG, Gusella JF, Ramesh V, Solomon F, Marchesi VT, Tsukita S, Tsukita S, Hoover KB, et al.

Trends Biochem Sci. 1998 Aug;23(8):281-2. Review. No abstract available. PMID: 9757824 [PubMed - indexed for MEDLINE]Related articles

Organization of the human protein 4.1 genomic locus: new insights into the tissue-specific alternative splicing of the pre-mRNA.

Baklouti F, Huang SC, Vulliamy TJ, Delaunay J, Benz EJ Jr.

Genomics. 1997 Feb 1;39(3):289-302.PMID: 9119366 [PubMed - indexed for MEDLINE]Related articles

Na, K-ATPase isoform gene expression in normal and hypertrophied dog heart.

Zahler R, Gilmore-Hebert M, Sun W, Benz EJ.

Basic Res Cardiol. 1996 May-Jun;91(3):256-66.PMID: 8831945 [PubMed - indexed for MEDLINE]Related articles

Asynchronous regulation of splicing events within protein 4.1 pre-mRNA during erythroid differentiation.

Baklouti F, Huang SC, Tang TK, Delaunay J, Marchesi VT, Benz EJ Jr.

Blood. 1996 May 1;87(9):3934-41.PMID: 8611723 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of tissue specific alternative pre-mRNA splicing in the differentiation of the erythrocyte membrane.

Benz EJ Jr, Huang SC.

Trans Am Clin Climatol Assoc. 1997;108:78-95. Review.PMID: 9108669 [PubMed - indexed for MEDLINE]Related articlesFree article

The thalassemia syndromes: lessons from molecular medicines index case.

Benz EJ Jr.

Trans Am Clin Climatol Assoc. 1996;107:20-36; discussion 35-6. Review.PMID: 8725557 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene therapy in hematology.

Benz EJ, Bank A.

Rev Invest Clin. 1994 Apr;Suppl:143-6. Review. No abstract available. PMID: 7886298 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific alternative splicing of protein 4.1 inserts an exon necessary for formation of the ternary complex with erythrocyte spectrin and F-actin.

Horne WC, Huang SC, Becker PS, Tang TK, Benz EJ Jr.

Blood. 1993 Oct 15;82(8):2558-63.PMID: 8400303 [PubMed - indexed for MEDLINE]Related articlesFree article

Posttranscriptional regulation of colony-stimulating factor-1 (CSF-1) and CSF-1 receptor gene expression during inhibition of phorbol-ester-induced monocytic differentiation by dexamethasone and cyclosporin A: potential involvement of a destabilizing protein.

Chambers SK, Gilmore-Hebert M, Wang Y, Rodov S, Benz EJ Jr, Kacinski BM.

Exp Hematol. 1993 Sep;21(10):1328-34.PMID: 8359233 [PubMed - indexed for MEDLINE]Related articles

Expression of alpha isoforms of the Na,K-ATPase in human heart.

Zahler R, Gilmore-Hebert M, Baldwin JC, Franco K, Benz EJ Jr.

Biochim Biophys Acta. 1993 Jul 4;1149(2):189-94.PMID: 8391840 [PubMed - indexed for MEDLINE]Related articles

Genomic structure of the locus encoding protein 4.1. Structural basis for complex combinational patterns of tissue-specific alternative RNA splicing.

Huang JP, Tang CJ, Kou GH, Marchesi VT, Benz EJ Jr, Tang TK.

J Biol Chem. 1993 Feb 15;268(5):3758-66.PMID: 8429050 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalent skipping of an individual exon accounts for shortened protein 4.1 Presles.

Feddal S, Hayette S, Baklouti F, Rimokh R, Wilmotte R, Magaud JP, Maréchal J, Benz EJ Jr, Girot R, Delaunay J, et al.

Blood. 1992 Dec 1;80(11):2925-30.PMID: 1450417 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential translation of the Na,K-ATPase subunit mRNAs.

Devarajan P, Gilmore-Hebert M, Benz EJ Jr.

J Biol Chem. 1992 Nov 5;267(31):22435-9.PMID: 1331056 [PubMed - indexed for MEDLINE]Related articlesFree article

Homozygous 4.1(-) hereditary elliptocytosis associated with a point mutation in the downstream initiation codon of protein 4.1 gene.

Dalla Venezia N, Gilsanz F, Alloisio N, Ducluzeau MT, Benz EJ Jr, Delaunay J.

J Clin Invest. 1992 Nov;90(5):1713-7.PMID: 1430200 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in Na,K-ATPase gene expression during granulocytic differentiation of HL60 cells.

Chambers SK, Gilmore-Hebert M, Kacinski BM, Benz EJ Jr.

Blood. 1992 Sep 15;80(6):1559-64.PMID: 1325845 [PubMed - indexed for MEDLINE]Related articlesFree article

Deamidation of human erythrocyte protein 4.1: possible role in aging.

Inaba M, Gupta KC, Kuwabara M, Takahashi T, Benz EJ Jr, Maede Y.

Blood. 1992 Jun 15;79(12):3355-61.PMID: 1596575 [PubMed - indexed for MEDLINE]Related articlesFree article

Lactoferrin gene promoter: structural integrity and nonexpression in HL60 cells.

Johnston JJ, Rintels P, Chung J, Sather J, Benz EJ Jr, Berliner N.

Blood. 1992 Jun 1;79(11):2998-3006.PMID: 1586744 [PubMed - indexed for MEDLINE]Related articlesFree article

The A2 isoform of rat Na+,K(+)-adenosine triphosphatase is active and exhibits high ouabain affinity when expressed in transfected fibroblasts.

Kolansky DM, Brines ML, Gilmore-Hebert M, Benz EJ Jr.

FEBS Lett. 1992 Jun 1;303(2-3):147-53.PMID: 1376695 [PubMed - indexed for MEDLINE]Related articles

Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability.

Baserga SJ, Benz EJ Jr.

Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2935-9.PMID: 1557399 [PubMed - indexed for MEDLINE]Related articlesFree article

The stem cell mavens had a blast. Second International Symposium on the Molecular Biology of Hematopoiesis, Innsbruck, Austria, July 14-18, 1991.

Abraham NG, Benz EJ Jr, Karlsson S, Lutton J, Clark SC.

New Biol. 1992 Jan;4(1):42-7. No abstract available. PMID: 1346971 [PubMed - indexed for MEDLINE]Related articles

The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase.

Zahler R, Brines M, Kashgarian M, Benz EJ Jr, Gilmore-Hebert M.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):99-103.PMID: 1309618 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential utilization of translation initiation sites in alternatively spliced mRNAs arising from the protein 4.1 gene.

Huang SC, Baklouti F, Tang TK, Benz EJ Jr.

Trans Assoc Am Physicians. 1992;105:165-71. No abstract available. PMID: 1308992 [PubMed - indexed for MEDLINE]Related articles

Molecular analysis of hereditary elliptocytosis with reduced protein 4.1 in the French Northern Alps.

Feddal S, Brunet G, Roda L, Chabanis S, Alloisio N, Morlé L, Ducluzeau MT, Maréchal J, Robert JM, Benz EJ Jr, et al.

Blood. 1991 Oct 15;78(8):2113-9.PMID: 1912588 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of the Na(+)-K(+)-ATPase alpha 3-isoform in multinucleated macrophages.

Vignery A, Wang F, Qian HY, Benz EJ Jr, Gilmore-Hebert M.

Am J Physiol. 1991 May;260(5 Pt 2):F704-9.PMID: 1852120 [PubMed - indexed for MEDLINE]Related articles