PubMed

Safety overview of postmarketing and clinical experience of sodium oxybate (Xyrem): abuse, misuse, dependence, and diversion.

Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL.

J Clin Sleep Med. 2009 Aug 15;5(4):365-71.PMID: 19968016 [PubMed - in process]Related articles

Chinese "herbal" cigarettes are as carcinogenic and addictive as regular cigarettes.

Gan Q, Yang J, Yang G, Goniewicz M, Benowitz NL, Glantz SA.

Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3497-501.PMID: 19959701 [PubMed - in process]Related articles

Utility and relationships of biomarkers of smoking in African-American light smokers.

Ho MK, Faseru B, Choi WS, Nollen NL, Mayo MS, Thomas JL, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF.

Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3426-34.PMID: 19959692 [PubMed - in process]Related articles

Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Goniewicz ML, Havel CM, Peng MW, Jacob P 3rd, Dempsey D, Yu L, Zielinska-Danch W, Koszowski B, Czogala J, Sobczak A, Benowitz NL.

Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3421-5.PMID: 19959691 [PubMed - in process]Related articles

Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study.

Bernert JT, Jacob P 3rd, Holiday DB, Benowitz NL, Sosnoff CS, Doig MV, Feyerabend C, Aldous KM, Sharifi M, Kellogg MD, Langman LJ.

Nicotine Tob Res. 2009 Dec;11(12):1458-66. Epub 2009 Nov 23.PMID: 19933777 [PubMed - in process]Related articles

Counseling to reduce children's secondhand smoke exposure and help parents quit smoking: a controlled trial.

Hovell MF, Zakarian JM, Matt GE, Liles S, Jones JA, Hofstetter CR, Larson SN, Benowitz NL.

Nicotine Tob Res. 2009 Dec;11(12):1383-94. Epub 2009 Oct 29.PMID: 19875762 [PubMed - in process]Related articles

Genetic influences on individual differences in nicotine glucuronidation.

Lessov-Schlaggar CN, Benowitz NL, Jacob P, Swan GE.

Twin Res Hum Genet. 2009 Oct;12(5):507-13.PMID: 19803778 [PubMed - in process]Related articles

Prevalence of smoking assessed biochemically in an urban public hospital: a rationale for routine cotinine screening.

Benowitz NL, Schultz KE, Haller CA, Wu AH, Dains KM, Jacob P 3rd.

Am J Epidemiol. 2009 Oct 1;170(7):885-91. Epub 2009 Aug 27.PMID: 19713287 [PubMed - indexed for MEDLINE]Related articles

Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Eisner MD, Jacob P 3rd, Benowitz NL, Balmes J, Blanc PD.

Nicotine Tob Res. 2009 Aug;11(8):945-53. Epub 2009 Jul 8.PMID: 19587064 [PubMed - indexed for MEDLINE]Related articles

Calibrating self-reported measures of maternal smoking in pregnancy via bioassays using a Monte Carlo approach.

Dukic VM, Niessner M, Pickett KE, Benowitz NL, Wakschlag LS.

Int J Environ Res Public Health. 2009 Jun;6(6):1744-59. Epub 2009 Jun 3.PMID: 19578458 [PubMed - indexed for MEDLINE]Related articlesFree article

Urine nicotine metabolite concentrations in relation to plasma cotinine during low-level nicotine exposure.

Benowitz NL, Dains KM, Dempsey D, Herrera B, Yu L, Jacob P 3rd.

Nicotine Tob Res. 2009 Aug;11(8):954-60. Epub 2009 Jun 12.PMID: 19525206 [PubMed - indexed for MEDLINE]Related articles

Dopamine genes and nicotine dependence in treatment-seeking and community smokers.

Bergen AW, Conti DV, Van Den Berg D, Lee W, Liu J, Li D, Guo N, Mi H, Thomas PD, Lessov-Schlaggar CN, Krasnow R, He Y, Nishita D, Jiang R, McClure JB, Tildesley E, Hops H, Tyndale RF, Benowitz NL, Lerman C, Swan GE.

Neuropsychopharmacology. 2009 Sep;34(10):2252-64. Epub 2009 Jun 3.PMID: 19494806 [PubMed - indexed for MEDLINE]Related articles

Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine.

Swan GE, Lessov-Schlaggar CN, Bergen AW, He Y, Tyndale RF, Benowitz NL.

Pharmacogenet Genomics. 2009 May;19(5):388-98.PMID: 19300303 [PubMed - indexed for MEDLINE]Related articles

Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers.

Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF.

Clin Pharmacol Ther. 2009 Jun;85(6):635-43. Epub 2009 Mar 11.PMID: 19279561 [PubMed - indexed for MEDLINE]Related articles

Progressive commercial cigarette yield reduction: biochemical exposure and behavioral assessment.

Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P 3rd.

Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):876-83. Epub 2009 Mar 3.PMID: 19258480 [PubMed - indexed for MEDLINE]Related articles

Withdrawal in adolescent light smokers following 24-hour abstinence.

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB.

Nicotine Tob Res. 2009 Feb;11(2):185-9. Epub 2009 Feb 25.PMID: 19246428 [PubMed - indexed for MEDLINE]Related articles

Nicotine chemistry, metabolism, kinetics and biomarkers.

Benowitz NL, Hukkanen J, Jacob P 3rd.

Handb Exp Pharmacol. 2009;(192):29-60. Review.PMID: 19184645 [PubMed - indexed for MEDLINE]Related articles

Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004.

Benowitz NL, Bernert JT, Caraballo RS, Holiday DB, Wang J.

Am J Epidemiol. 2009 Jan 15;169(2):236-48. Epub 2008 Nov 19.PMID: 19019851 [PubMed - indexed for MEDLINE]Related articles

Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry.

Jacob P 3rd, Havel C, Lee DH, Yu L, Eisner MD, Benowitz NL.

Anal Chem. 2008 Nov 1;80(21):8115-21. Epub 2008 Oct 8.PMID: 18841944 [PubMed - indexed for MEDLINE]Related articles

Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics.

Benowitz NL.

Annu Rev Pharmacol Toxicol. 2009;49:57-71. Review.PMID: 18834313 [PubMed - indexed for MEDLINE]Related articles

Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers.

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB.

Pediatrics. 2008 Sep;122(3):e643-7.PMID: 18762498 [PubMed - indexed for MEDLINE]Related articlesFree article

A randomized trial of nicotine nasal spray in adolescent smokers.

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB.

Pediatrics. 2008 Sep;122(3):e595-600.PMID: 18762494 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotine and postoperative management of pain.

Benowitz NL.

Anesth Analg. 2008 Sep;107(3):739-41. No abstract available. PMID: 18713874 [PubMed - indexed for MEDLINE]Related articlesFree article

Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood.

Perkins KA, Lerman C, Grottenthaler A, Ciccocioppo MM, Milanak M, Conklin CA, Bergen AW, Benowitz NL.

Behav Pharmacol. 2008 Sep;19(5-6):641-9.PMID: 18690118 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers.

Perkins KA, Lerman C, Coddington S, Jetton C, Karelitz JL, Wilson A, Jennings JR, Ferrell R, Bergen AW, Benowitz NL.

Behav Pharmacol. 2008 Sep;19(5-6):630-40.PMID: 18690117 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotine metabolism in pregnant and nonpregnant rabbits.

Tutka P, Dempsey DA, Jacob P 3rd, Benowitz NL, Kroetz DL.

Nicotine Tob Res. 2008 Aug;10(8):1385-90.PMID: 18686186 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma.

Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X.

J Natl Cancer Inst. 2008 Aug 6;100(15):1104-12. Epub 2008 Jul 29.PMID: 18664653 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.

Conti DV, Lee W, Li D, Liu J, Van Den Berg D, Thomas PD, Bergen AW, Swan GE, Tyndale RF, Benowitz NL, Lerman C; Pharmacogenetics of Nicotine Addiction and Treatment Consortium.

Hum Mol Genet. 2008 Sep 15;17(18):2834-48. Epub 2008 Jul 1.PMID: 18593715 [PubMed - indexed for MEDLINE]Related articlesFree article

Creating and evaluating genetic tests predictive of drug response.

Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM.

Nat Rev Drug Discov. 2008 Jul;7(7):568-74. Epub 2008 Jun 20.PMID: 18587383 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic influences in the variation in renal clearance of nicotine and cotinine.

Benowitz NL, Lessov-Schlaggar CN, Swan GE.

Clin Pharmacol Ther. 2008 Aug;84(2):243-7. Epub 2008 Apr 2.PMID: 18388871 [PubMed - indexed for MEDLINE]Related articles

Chocolate consumption in pregnancy and reduced likelihood of preeclampsia.

Triche EW, Grosso LM, Belanger K, Darefsky AS, Benowitz NL, Bracken MB.

Epidemiology. 2008 May;19(3):459-64.PMID: 18379424 [PubMed - indexed for MEDLINE]Related articlesFree article

Neurobiology of nicotine addiction: implications for smoking cessation treatment.

Benowitz NL.

Am J Med. 2008 Apr;121(4 Suppl 1):S3-10. Review.PMID: 18342164 [PubMed - indexed for MEDLINE]Related articles

Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction.

Benowitz NL.

Clin Pharmacol Ther. 2008 Apr;83(4):531-41. Epub 2008 Feb 27. Review.PMID: 18305452 [PubMed - indexed for MEDLINE]Related articles

The Women's Initiative for Nonsmoking (WINS) XI: age-related differences in smoking cessation responses among women with cardiovascular disease.

Doolan DM, Stotts NA, Benowitz NL, Covinsky KE, Froelicher ES.

Am J Geriatr Cardiol. 2008 Jan-Feb;17(1):37-47.PMID: 18174758 [PubMed - indexed for MEDLINE]Related articles

Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake?

Grosso LM, Triche E, Benowitz NL, Bracken MB.

Ann Epidemiol. 2008 Mar;18(3):172-8.PMID: 18083538 [PubMed - indexed for MEDLINE]Related articlesFree article

Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette.

Benowitz NL, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P 3rd.

Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2479-85.PMID: 18006940 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism.

Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P 3rd, Tyndale RF, Swan GE, Benowitz NL.

Pharmacogenet Genomics. 2007 Dec;17(12):1007-15.PMID: 18004205 [PubMed - indexed for MEDLINE]Related articles

Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation.

Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X.

Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2065-71.PMID: 17932354 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytisine for smoking cessation: a research agenda.

Etter JF, Lukas RJ, Benowitz NL, West R, Dresler CM.

Drug Alcohol Depend. 2008 Jan 1;92(1-3):3-8. Epub 2007 Sep 6. Review.PMID: 17825502 [PubMed - indexed for MEDLINE]Related articles

CHRNA4 and tobacco dependence: from gene regulation to treatment outcome.

Hutchison KE, Allen DL, Filbey FM, Jepson C, Lerman C, Benowitz NL, Stitzel J, Bryan A, McGeary J, Haughey HM.

Arch Gen Psychiatry. 2007 Sep;64(9):1078-86.PMID: 17768273 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational research in medication development for nicotine dependence.

Lerman C, LeSage MG, Perkins KA, O'Malley SS, Siegel SJ, Benowitz NL, Corrigall WA.

Nat Rev Drug Discov. 2007 Sep;6(9):746-62. Review.PMID: 17690709 [PubMed - indexed for MEDLINE]Related articles

Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia.

Williams JM, Gandhi KK, Steinberg ML, Foulds J, Ziedonis DM, Benowitz NL.

Nicotine Tob Res. 2007 Aug;9(8):873-81.PMID: 17654300 [PubMed - indexed for MEDLINE]Related articles

Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine.

Stepanov I, Hecht SS, Lindgren B, Jacob P 3rd, Wilson M, Benowitz NL.

Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1382-6.PMID: 17627002 [PubMed - indexed for MEDLINE]Related articlesFree article

Cigarette smoking and the personalization of irinotecan therapy.

Benowitz NL.

J Clin Oncol. 2007 Jul 1;25(19):2646-7. Epub 2007 Jun 11. No abstract available. PMID: 17563392 [PubMed - indexed for MEDLINE]Related articles

Genetic and environmental sources of variation in heart rate response to infused nicotine in twins.

Swan GE, Lessov-Schlaggar CN, Krasnow RE, Wilhelmsen KC, Jacob P 3rd, Benowitz NL.

Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1057-64.PMID: 17548663 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.

Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF.

Clin Pharmacol Ther. 2008 Jan;83(1):115-21. Epub 2007 May 23.PMID: 17522595 [PubMed - indexed for MEDLINE]Related articles

Vaporization as a smokeless cannabis delivery system: a pilot study.

Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, Benowitz NL.

Clin Pharmacol Ther. 2007 Nov;82(5):572-8. Epub 2007 Apr 11.PMID: 17429350 [PubMed - indexed for MEDLINE]Related articles

Cotinine levels in relation to smoking behavior and addiction in young adolescent smokers.

Rubinstein ML, Thompson PJ, Benowitz NL, Shiffman S, Moscicki AB.

Nicotine Tob Res. 2007 Jan;9(1):129-35.PMID: 17365743 [PubMed - indexed for MEDLINE]Related articles

The variability of urinary cotinine levels in young children: implications for measuring ETS exposure.

Matt GE, Hovell MF, Quintana PJ, Zakarian J, Liles S, Meltzer SB, Benowitz NL.

Nicotine Tob Res. 2007 Jan;9(1):83-92.PMID: 17365739 [PubMed - indexed for MEDLINE]Related articles

Nicotine, cotinine, withdrawal, and craving patterns during smoking and nicotine nasal spray use: results from a pilot study with African American men.

Mabry PL, Tooze JA, Moser RP, Augustson EM, Malcolm RJ, Benowitz NL.

Nicotine Tob Res. 2007 Jan;9(1):65-82.PMID: 17365738 [PubMed - indexed for MEDLINE]Related articles