PubMed

Atypical Protein Kinase C Activity in the Hypothalamus Is Required for Lipopolysaccharide-Mediated Sickness Responses.

Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW.

Endocrinology. 2009 Oct 9. [Epub ahead of print]PMID: 19819945 [PubMed - as supplied by publisher]Related articles

Insulin, leptin and reward.

Davis JF, Choi DL, Benoit SC.

Trends Endocrinol Metab. 2009 Oct 7. [Epub ahead of print]PMID: 19818643 [PubMed - as supplied by publisher]Related articles

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents.

Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ.

J Clin Invest. 2009 Sep;119(9):2577-89. doi: 10.1172/JCI36714. Epub 2009 Aug 10.PMID: 19726875 [PubMed - indexed for MEDLINE]Related articlesFree article

Dominant rats are natural risk takers and display increased motivation for food reward.

Davis JF, Krause EG, Melhorn SJ, Sakai RR, Benoit SC.

Neuroscience. 2009 Aug 4;162(1):23-30. Epub 2009 Apr 22.PMID: 19393296 [PubMed - indexed for MEDLINE]Related articles

Long-term behavioral consequences of prenatal MDMA exposure.

Thompson VB, Heiman J, Chambers JB, Benoit SC, Buesing WR, Norman MK, Norman AB, Lipton JW.

Physiol Behav. 2009 Mar 23;96(4-5):593-601. Epub 2008 Dec 31.PMID: 19162054 [PubMed - indexed for MEDLINE]Related articles

Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat.

Davis JF, Tracy AL, Schurdak JD, Tschöp MH, Lipton JW, Clegg DJ, Benoit SC.

Behav Neurosci. 2008 Dec;122(6):1257-63.PMID: 19045945 [PubMed - indexed for MEDLINE]Related articles

Insulin, leptin, and food reward: update 2008.

Figlewicz DP, Benoit SC.

Am J Physiol Regul Integr Comp Physiol. 2009 Jan;296(1):R9-R19. Epub 2008 Oct 22. Review.PMID: 18945945 [PubMed - indexed for MEDLINE]Related articles

Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation.

Davidson TL, Chan K, Jarrard LE, Kanoski SE, Clegg DJ, Benoit SC.

Hippocampus. 2009 Mar;19(3):235-52.PMID: 18831000 [PubMed - indexed for MEDLINE]Related articles

Novel functions of orexigenic hypothalamic peptides: from genes to behavior.

Benoit SC, Tracy AL, Davis JF, Choi D, Clegg DJ.

Nutrition. 2008 Sep;24(9):843-7. Review.PMID: 18725081 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin type 1 receptors in the subfornical organ mediate the drinking and hypothalamic-pituitary-adrenal response to systemic isoproterenol.

Krause EG, Melhorn SJ, Davis JF, Scott KA, Ma LY, de Kloet AD, Benoit SC, Woods SC, Sakai RR.

Endocrinology. 2008 Dec;149(12):6416-24. Epub 2008 Aug 7.PMID: 18687780 [PubMed - indexed for MEDLINE]Related articles

Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.

Nogueiras R, López M, Lage R, Perez-Tilve D, Pfluger P, Mendieta-Zerón H, Sakkou M, Wiedmer P, Benoit SC, Datta R, Dong JZ, Culler M, Sleeman M, Vidal-Puig A, Horvath T, Treier M, Diéguez C, Tschöp MH.

Endocrinology. 2008 Jun;149(6):3009-15. Epub 2008 Feb 28.PMID: 18308842 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice with chronically increased circulating ghrelin develop age-related glucose intolerance.

Reed JA, Benoit SC, Pfluger PT, Tschöp MH, D'Alessio DA, Seeley RJ.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E752-60. Epub 2008 Feb 12.PMID: 18270302 [PubMed - indexed for MEDLINE]Related articlesFree article

The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer.

Tracy AL, Clegg DJ, Johnson JD, Davidson TL, Benoit SC.

Pharmacol Biochem Behav. 2008 May;89(3):263-71. Epub 2007 Dec 23.PMID: 18234306 [PubMed - indexed for MEDLINE]Related articlesFree article

Voluntary consumption of ethyl oleate reduces food intake and body weight in rats.

Kemp CJ, D'Alessio DA, Scott RO, Kelm GR, Meller ST, Barrera JG, Seeley RJ, Clegg DJ, Benoit SC.

Physiol Behav. 2008 Mar 18;93(4-5):912-8. Epub 2007 Dec 23.PMID: 18234242 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of mice lacking the gene for cholecystokinin.

Lo CM, Samuelson LC, Chambers JB, King A, Heiman J, Jandacek RJ, Sakai RR, Benoit SC, Raybould HE, Woods SC, Tso P.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R803-10. Epub 2007 Dec 26.PMID: 18160529 [PubMed - indexed for MEDLINE]Related articles

Behavioral controls of food intake.

Benoit SC, Tracy AL.

Peptides. 2008 Jan;29(1):139-47. Review.PMID: 18068269 [PubMed - indexed for MEDLINE]Related articlesFree article

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.

Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G610-8. Epub 2007 Nov 29.PMID: 18048479 [PubMed - indexed for MEDLINE]Related articlesFree article

A potential role for the hippocampus in energy intake and body weight regulation.

Davidson TL, Kanoski SE, Schier LA, Clegg DJ, Benoit SC.

Curr Opin Pharmacol. 2007 Dec;7(6):613-6. Epub 2007 Nov 26. Review.PMID: 18032108 [PubMed - indexed for MEDLINE]Related articlesFree article

Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight.

Eric Hu X, Wos JA, Dowty ME, Suchanek PM, Ji W, Chambers JB, Benoit SC, Clegg DJ, Reizes O.

J Pharmacol Exp Ther. 2008 Jan;324(1):206-13. Epub 2007 Oct 11.PMID: 17932246 [PubMed - indexed for MEDLINE]Related articlesFree article

The central melanocortin system directly controls peripheral lipid metabolism.

Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH.

J Clin Invest. 2007 Nov;117(11):3475-88.PMID: 17885689 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of syndecans in the regulation of body weight and synaptic plasticity.

Reizes O, Benoit SC, Clegg DJ.

Int J Biochem Cell Biol. 2008;40(1):28-45. Epub 2007 Jun 30. Review.PMID: 17698399 [PubMed - indexed for MEDLINE]Related articles

Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats.

Davis JF, Melhorn SJ, Shurdak JD, Heiman JU, Tschöp MH, Clegg DJ, Benoit SC.

Physiol Behav. 2007 Dec 5;92(5):924-30. Epub 2007 Jul 5.PMID: 17689576 [PubMed - indexed for MEDLINE]Related articlesFree article

Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats.

Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N.

Diabetes. 2007 Apr;56(4):1051-8. Epub 2007 Jan 24. Erratum in: Diabetes. 2007 Oct;56(10):2649. PMID: 17251274 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats.

Brown LM, Benoit SC, Woods SC, Clegg DJ.

Peptides. 2007 Mar;28(3):612-6. Epub 2006 Dec 28.PMID: 17196305 [PubMed - indexed for MEDLINE]Related articles

The regulation of alcohol intake by melanin-concentrating hormone in rats.

Duncan EA, Rider TR, Jandacek RJ, Clegg DJ, Benoit SC, Tso P, Woods SC.

Pharmacol Biochem Behav. 2006 Dec;85(4):728-35. Epub 2006 Dec 22.PMID: 17188345 [PubMed - indexed for MEDLINE]Related articles

Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36.

Pfluger PT, Kampe J, Castaneda TR, Vahl T, D'Alessio DA, Kruthaupt T, Benoit SC, Cuntz U, Rochlitz HJ, Moehlig M, Pfeiffer AF, Koebnick C, Weickert MO, Otto B, Spranger J, Tschöp MH.

J Clin Endocrinol Metab. 2007 Feb;92(2):583-8. Epub 2006 Nov 21.PMID: 17119001 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice.

Brown LM, Clegg DJ, Benoit SC, Woods SC.

Physiol Behav. 2006 Dec 30;89(5):687-91. Epub 2006 Sep 18.PMID: 16979194 [PubMed - indexed for MEDLINE]Related articles

Role for dopamine-3 receptor in the hyperphagia of an unanticipated high-fat meal in rats.

Davis JF, McQuade JA, Drazen DL, Woods SC, Seeley RJ, Benoit SC.

Pharmacol Biochem Behav. 2006 Sep;85(1):190-7. Epub 2006 Sep 14.PMID: 16978686 [PubMed - indexed for MEDLINE]Related articles

Modulation of phosphoinositide-protein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness.

McNamara RK, Ostrander M, Abplanalp W, Richtand NM, Benoit SC, Clegg DJ.

Prostaglandins Leukot Essent Fatty Acids. 2006 Oct-Nov;75(4-5):237-57. Epub 2006 Aug 28. Review.PMID: 16935483 [PubMed - indexed for MEDLINE]Related articles

Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.

Sanna B, Brandt EB, Kaiser RA, Pfluger P, Witt SA, Kimball TR, van Rooij E, De Windt LJ, Rothenberg ME, Tschop MH, Benoit SC, Molkentin JD.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7327-32. Epub 2006 Apr 28.PMID: 16648267 [PubMed - indexed for MEDLINE]Related articlesFree article

Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism.

Perez-Tilve D, Nogueiras R, Mallo F, Benoit SC, Tschoep M.

Endocrine. 2006 Feb;29(1):61-71. Review. Erratum in: Endocrine. 2006 Apr;29(2):383. PMID: 16622293 [PubMed - indexed for MEDLINE]Related articles

Gonadal hormones determine sensitivity to central leptin and insulin.

Clegg DJ, Brown LM, Woods SC, Benoit SC.

Diabetes. 2006 Apr;55(4):978-87. Erratum in: Diabetes. 2007 Oct;56(10):2649. Dosage error in article text. PMID: 16567519 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin controls hippocampal spine synapse density and memory performance.

Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL.

Nat Neurosci. 2006 Mar;9(3):381-8. Epub 2006 Feb 19.PMID: 16491079 [PubMed - indexed for MEDLINE]Related articles

A role for syndecan-3 in the melanocortin regulation of energy balance.

Reizes O, Clegg DJ, Strader AD, Benoit SC.

Peptides. 2006 Feb;27(2):274-80. Epub 2005 Nov 11. Review.PMID: 16289473 [PubMed - indexed for MEDLINE]Related articles

PYY3-36 as an anti-obesity drug target.

Boggiano MM, Chandler PC, Oswald KD, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Schindler M, Arndt K, Rudolf K, Mark M, Schoelch C, Joost HG, Klaus S, Thöne-Reineke C, Benoit SC, Seeley RJ, Beck-Sickinger AG, Koglin N, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Deng XY, Whitcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Ortmann S, Castañeda TR, Tschöp M.

Obes Rev. 2005 Nov;6(4):307-22. Review.PMID: 16246216 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake.

Gotoh K, Liu M, Benoit SC, Clegg DJ, Davidson WS, D'Alessio D, Seeley RJ, Tso P, Woods SC.

Am J Physiol Regul Integr Comp Physiol. 2006 Jan;290(1):R202-7. Epub 2005 Sep 15.PMID: 16166201 [PubMed - indexed for MEDLINE]Related articles

The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation.

Davidson TL, Kanoski SE, Tracy AL, Walls EK, Clegg D, Benoit SC.

Peptides. 2005 Sep;26(9):1602-10. Epub 2005 Mar 17.PMID: 16112399 [PubMed - indexed for MEDLINE]Related articles

The many faces of ghrelin: new perspectives for nutrition research?

Otto B, Spranger J, Benoit SC, Clegg DJ, Tschöp MH.

Br J Nutr. 2005 Jun;93(6):765-71. Review.PMID: 16022744 [PubMed - indexed for MEDLINE]Related articles

The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides.

Benoit SC, Clegg DJ, Woods SC, Seeley RJ.

Peptides. 2005 May;26(5):751-7. Epub 2005 Jan 23.PMID: 15808905 [PubMed - indexed for MEDLINE]Related articles

PYY3-36 "monkeys around" with energy balance.

Benoit SC, Tschöp MH.

Am J Physiol Regul Integr Comp Physiol. 2005 Feb;288(2):R358-9. No abstract available. PMID: 15637174 [PubMed - indexed for MEDLINE]Related articles

Consumption of a high-fat diet alters the homeostatic regulation of energy balance.

Woods SC, D'Alessio DA, Tso P, Rushing PA, Clegg DJ, Benoit SC, Gotoh K, Liu M, Seeley RJ.

Physiol Behav. 2004 Dec 30;83(4):573-8. Review.PMID: 15621062 [PubMed - indexed for MEDLINE]Related articles

Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet.

Clegg DJ, Benoit SC, Reed JA, Woods SC, Dunn-Meynell A, Levin BE.

Am J Physiol Regul Integr Comp Physiol. 2005 Apr;288(4):R981-6. Epub 2004 Dec 16.PMID: 15604298 [PubMed - indexed for MEDLINE]Related articles

Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals.

Woods SC, Benoit SC, Clegg DJ, Seeley RJ.

Best Pract Res Clin Endocrinol Metab. 2004 Dec;18(4):497-515. Review.PMID: 15533772 [PubMed - indexed for MEDLINE]Related articles

Mice lacking the syndecan-3 gene are resistant to diet-induced obesity.

Strader AD, Reizes O, Woods SC, Benoit SC, Seeley RJ.

J Clin Invest. 2004 Nov;114(9):1354-60. Erratum in: J Clin Invest. 2004 Dec;114(11):1686. PMID: 15520868 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiology: does gut hormone PYY3-36 decrease food intake in rodents?

Tschöp M, Castañeda TR, Joost HG, Thöne-Reineke C, Ortmann S, Klaus S, Hagan MM, Chandler PC, Oswald KD, Benoit SC, Seeley RJ, Kinzig KP, Moran TH, Beck-sickinger AG, Koglin N, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Schindler M, Arndt K, Rudolf K, Mark M, Deng XY, Whitcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Craney S, Flora D, Smiley D, Heiman ML.

Nature. 2004 Jul 8;430(6996):1 p following 165; discussion 2 p following 165. Erratum in: Nature. 2004 Sep 23;431(7007):1038. Withcomb, DC [corrected to Whitcomb, DC]. PMID: 15243972 [PubMed - indexed for MEDLINE]Related articles

Intraventricular insulin and leptin reverse place preference conditioned with high-fat diet in rats.

Figlewicz DP, Bennett J, Evans SB, Kaiyala K, Sipols AJ, Benoit SC.

Behav Neurosci. 2004 Jun;118(3):479-87.PMID: 15174925 [PubMed - indexed for MEDLINE]Related articles

High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene.

McQuade JA, Benoit SC, Xu M, Woods SC, Seeley RJ.

Behav Brain Res. 2004 May 5;151(1-2):313-9.PMID: 15084447 [PubMed - indexed for MEDLINE]Related articles

Insulin and leptin as adiposity signals.

Benoit SC, Clegg DJ, Seeley RJ, Woods SC.

Recent Prog Horm Res. 2004;59:267-85. Review.PMID: 14749506 [PubMed - indexed for MEDLINE]Related articlesFree article

7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens.

McQuade JA, Benoit SC, Woods SC, Seeley RJ.

Pharmacol Biochem Behav. 2003 Dec;76(3-4):517-23.PMID: 14643851 [PubMed - indexed for MEDLINE]Related articles

Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII.

Benoit SC, Clegg DJ, Barrera JG, Seeley RJ, Woods SC.

Diabetes. 2003 Nov;52(11):2684-8.PMID: 14578286 [PubMed - indexed for MEDLINE]Related articlesFree article