PubMed

Generation of definitive endoderm from human embryonic stem cells cultured in feeder layer-free conditions.

King CC, Beattie GM, Lopez AD, Hayek A.

Regen Med. 2008 Mar;3(2):175-80.PMID: 18307401 [PubMed - indexed for MEDLINE]Related articles

Global gene expression profiling and histochemical analysis of the developing human fetal pancreas.

Sarkar SA, Kobberup S, Wong R, Lopez AD, Quayum N, Still T, Kutchma A, Jensen JN, Gianani R, Beattie GM, Jensen J, Hayek A, Hutton JC.

Diabetologia. 2008 Feb;51(2):285-97. Epub 2007 Dec 18.PMID: 18094957 [PubMed - indexed for MEDLINE]Related articles

Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells.

Kayali AG, Flores LE, Lopez AD, Kutlu B, Baetge E, Kitamura R, Hao E, Beattie GM, Hayek A.

Diabetes. 2007 Mar;56(3):703-8.PMID: 17327439 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.

Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6907-12. Epub 2006 Apr 21.PMID: 16632596 [PubMed - indexed for MEDLINE]Related articlesFree article

Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers.

Beattie GM, Lopez AD, Bucay N, Hinton A, Firpo MT, King CC, Hayek A.

Stem Cells. 2005 Apr;23(4):489-95.PMID: 15790770 [PubMed - indexed for MEDLINE]Related articlesFree article

Maintenance of pluripotency in human embryonic stem cells is STAT3 independent.

Humphrey RK, Beattie GM, Lopez AD, Bucay N, King CC, Firpo MT, Rose-John S, Hayek A.

Stem Cells. 2004;22(4):522-30.PMID: 15277698 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas.

Humphrey RK, Bucay N, Beattie GM, Lopez A, Messam CA, Cirulli V, Hayek A.

Diabetes. 2003 Oct;52(10):2519-25.PMID: 14514635 [PubMed - indexed for MEDLINE]Related articlesFree article

Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells.

Movassat J, Beattie GM, Lopez AD, Portha B, Hayek A.

Diabetologia. 2003 Jun;46(6):822-9. Epub 2003 Jun 11.PMID: 12802496 [PubMed - indexed for MEDLINE]Related articles

Alternatives to unmodified human islets for transplantation.

Hayek A, Beattie GM.

Curr Diab Rep. 2002 Aug;2(4):371-6. Review.PMID: 12643198 [PubMed - indexed for MEDLINE]Related articles

A novel approach to increase human islet cell mass while preserving beta-cell function.

Beattie GM, Montgomery AM, Lopez AD, Hao E, Perez B, Just ML, Lakey JR, Hart ME, Hayek A.

Diabetes. 2002 Dec;51(12):3435-9.PMID: 12453897 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells.

Movassat J, Beattie GM, Lopez AD, Hayek A.

J Clin Endocrinol Metab. 2002 Oct;87(10):4775-81.PMID: 12364473 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth and genetic modification of human beta-cells and beta-cell precursors.

Beattie GM, Hayek A, Levine F.

Genet Eng (N Y). 2000;22:99-120. Review. No abstract available. PMID: 11501383 [PubMed - indexed for MEDLINE]Related articles

A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth.

Demeterco C, Beattie GM, Dib SA, Lopez AD, Hayek A.

J Clin Endocrinol Metab. 2000 Oct;85(10):3892-7.PMID: 11061554 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells.

Cirulli V, Beattie GM, Klier G, Ellisman M, Ricordi C, Quaranta V, Frasier F, Ishii JK, Hayek A, Salomon DR.

J Cell Biol. 2000 Sep 18;150(6):1445-60.PMID: 10995448 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection from cell death in cultured human fetal pancreatic cells.

Beattie GM, Leibowitz G, Lopez AD, Levine F, Hayek A.

Cell Transplant. 2000 May-Jun;9(3):431-8.PMID: 10972342 [PubMed - indexed for MEDLINE]Related articles

Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro.

Halvorsen TL, Beattie GM, Lopez AD, Hayek A, Levine F.

J Endocrinol. 2000 Jul;166(1):103-9.PMID: 10856888 [PubMed - indexed for MEDLINE]Related articlesFree article

PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line.

Itkin-Ansari P, Demeterco C, Bossie S, de la Tour DD, Beattie GM, Movassat J, Mally MI, Hayek A, Levine F.

Mol Endocrinol. 2000 Jun;14(6):814-22.PMID: 10847584 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained proliferation of PDX-1+ cells derived from human islets.

Beattie GM, Itkin-Ansari P, Cirulli V, Leibowitz G, Lopez AD, Bossie S, Mally MI, Levine F, Hayek A.

Diabetes. 1999 May;48(5):1013-9.PMID: 10331405 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene transfer to human pancreatic endocrine cells using viral vectors.

Leibowitz G, Beattie GM, Kafri T, Cirulli V, Lopez AD, Hayek A, Levine F.

Diabetes. 1999 Apr;48(4):745-53.PMID: 10102690 [PubMed - indexed for MEDLINE]Related articlesFree article

Microfabricated immunoisolating biocapsules.

Desai TA, Chu WH, Tu JK, Beattie GM, Hayek A, Ferrari M.

Biotechnol Bioeng. 1998 Jan 5;57(1):118-20.PMID: 10099185 [PubMed - indexed for MEDLINE]Related articles

Transplantation of human fetal pancreas: fresh vs. cultured fetal islets or ICCS.

Beattie GM, Lopez AD, Otonkoski T, Hayek A.

J Mol Med. 1999 Jan;77(1):70-3.PMID: 9930931 [PubMed - indexed for MEDLINE]Related articles

KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development.

Cirulli V, Crisa L, Beattie GM, Mally MI, Lopez AD, Fannon A, Ptasznik A, Inverardi L, Ricordi C, Deerinck T, Ellisman M, Reisfeld RA, Hayek A.

J Cell Biol. 1998 Mar 23;140(6):1519-34.PMID: 9508783 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental transplantation of human fetal and adult pancreatic islets.

Hayek A, Beattie GM.

J Clin Endocrinol Metab. 1997 Aug;82(8):2471-5.PMID: 9253320 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation.

Ptasznik A, Beattie GM, Mally MI, Cirulli V, Lopez A, Hayek A.

J Cell Biol. 1997 Jun 2;137(5):1127-36.PMID: 9166412 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of a human fetal pancreatic islet cell line.

Wang S, Beattie GM, Mally MI, Lopez AD, Hayek A, Levine F.

Transplant Proc. 1997 Jun;29(4):2219. No abstract available. PMID: 9193600 [PubMed - indexed for MEDLINE]Related articles

Ex vivo expansion of human pancreatic endocrine cells.

Beattie GM, Cirulli V, Lopez AD, Hayek A.

J Clin Endocrinol Metab. 1997 Jun;82(6):1852-6.PMID: 9177395 [PubMed - indexed for MEDLINE]Related articlesFree article

Trehalose: a cryoprotectant that enhances recovery and preserves function of human pancreatic islets after long-term storage.

Beattie GM, Crowe JH, Lopez AD, Cirulli V, Ricordi C, Hayek A.

Diabetes. 1997 Mar;46(3):519-23.PMID: 9032112 [PubMed - indexed for MEDLINE]Related articles

Functional beta-cell mass after transplantation of human fetal pancreatic cells: differentiation or proliferation?

Beattie GM, Otonkoski T, Lopez AD, Hayek A.

Diabetes. 1997 Feb;46(2):244-8.PMID: 9000701 [PubMed - indexed for MEDLINE]Related articles

Processing, storage and experimental transplantation of human fetal pancreatic cells.

Hayek A, Beattie GM.

Ann Transplant. 1997;2(3):46-54. Review. No abstract available. PMID: 9869864 [PubMed - indexed for MEDLINE]Related articles

Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas.

Wang S, Beattie GM, Mally MI, Cirulli V, Itkin-Ansari P, Lopez AD, Hayek A, Levine F.

Cell Transplant. 1997 Jan-Feb;6(1):59-67.PMID: 9040956 [PubMed - indexed for MEDLINE]Related articles

Development of a VSV-G protein pseudotyped retroviral vector system expressing dominant oncogenes from a lacO-modified inducible LTR promoter.

Wang S, Beattie GM, Hayek A, Levine F.

Gene. 1996 Dec 5;182(1-2):145-50.PMID: 8982080 [PubMed - indexed for MEDLINE]Related articles

Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.

Beattie GM, Rubin JS, Mally MI, Otonkoski T, Hayek A.

Diabetes. 1996 Sep;45(9):1223-8.PMID: 8772726 [PubMed - indexed for MEDLINE]Related articles

E2A gene products are not required for insulin gene expression.

Itkin-Ansari P, Bain G, Beattie GM, Murre C, Hayek A, Levine F.

Endocrinology. 1996 Aug;137(8):3540-3.PMID: 8754784 [PubMed - indexed for MEDLINE]Related articles

Development of a cell line from the human fetal pancreas.

Levine F, Wang S, Beattie GM, Mally MI, Cirulli V, Lopez AD, Hayek A.

Transplant Proc. 1995 Dec;27(6):3410. No abstract available. PMID: 8540023 [PubMed - indexed for MEDLINE]Related articles

In vivo maturation and growth potential of human fetal pancreases: fresh versus cultured tissue.

Beattie GM, Lopez AD, Hayek A.

Transplant Proc. 1995 Dec;27(6):3343. No abstract available. PMID: 8539983 [PubMed - indexed for MEDLINE]Related articles

Growth factor/matrix-induced proliferation of human adult beta-cells.

Hayek A, Beattie GM, Cirulli V, Lopez AD, Ricordi C, Rubin JS.

Diabetes. 1995 Dec;44(12):1458-60.PMID: 7589854 [PubMed - indexed for MEDLINE]Related articles

Use of hepatocyte growth factor/scatter factor to increase transplantable human fetal islet cell mass.

Otonkoski T, Beattie GM, Lopez AD, Hayek A.

Transplant Proc. 1994 Dec;26(6):3334. No abstract available. PMID: 7998160 [PubMed - indexed for MEDLINE]Related articles

Outcome of human fetal pancreatic transplants according to implantation site.

Beattie GM, Hayek A.

Transplant Proc. 1994 Dec;26(6):3299. No abstract available. PMID: 7998141 [PubMed - indexed for MEDLINE]Related articles

Morphology and function of cultured human fetal pancreatic cells transplanted into athymic mice: a longitudinal study.

Beattie GM, Butler C, Hayek A.

Cell Transplant. 1994 Sep-Oct;3(5):421-5.PMID: 7827780 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells.

Otonkoski T, Beattie GM, Rubin JS, Lopez AD, Baird A, Hayek A.

Diabetes. 1994 Jul;43(7):947-53.PMID: 8013761 [PubMed - indexed for MEDLINE]Related articles

Differential integrin expression facilitates isolation of human fetal pancreatic epithelial cells.

Levine F, Beattie GM, Hayek A.

Cell Transplant. 1994 Jul-Aug;3(4):307-13.PMID: 7921635 [PubMed - indexed for MEDLINE]Related articles

Acid beta-galactosidase: a developmentally regulated marker of endocrine cell precursors in the human fetal pancreas.

Beattie GM, Levine F, Mally MI, Otonkoski T, O'Brien JS, Salomon DR, Hayek A.

J Clin Endocrinol Metab. 1994 May;78(5):1232-40.PMID: 8175983 [PubMed - indexed for MEDLINE]Related articles

Maturation and function of human fetal pancreatic cells after cryopreservation.

Beattie GM, Otonkoski T, Lopez AD, Hayek A.

Transplantation. 1993 Dec;56(6):1340-3.PMID: 8279000 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells.

Otonkoski T, Beattie GM, Mally MI, Ricordi C, Hayek A.

J Clin Invest. 1993 Sep;92(3):1459-66.PMID: 8104197 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet cell mass and the longevity of islet grafts in diabetic rats.

Beattie GM, Hayek A.

Cell Transplant. 1993 Mar-Apr;2(2):119-22.PMID: 8143078 [PubMed - indexed for MEDLINE]Related articles

Generation of viable isletlike cell clusters from cryopreserved human fetal pancreas.

Otonkoski T, Beattie GM, Lopez AD, Hayek A.

Transplant Proc. 1992 Dec;24(6):2832. No abstract available. PMID: 1465961 [PubMed - indexed for MEDLINE]Related articles

Intrapancreatic islet transplantation in experimental diabetes in the rat.

Hayek A, Beattie GM.

Metabolism. 1992 Dec;41(12):1367-9.PMID: 1461143 [PubMed - indexed for MEDLINE]Related articles

Reversal of experimental diabetes by injection of syngeneic islets into peripheral veins.

Hayek A, Beattie GM.

Cell Transplant. 1992;1(1):83-5.PMID: 1344294 [PubMed - indexed for MEDLINE]Related articles

Functional impact of attachment and purification in the short term culture of human pancreatic islets.

Beattie GM, Lappi DA, Baird A, Hayek A.

J Clin Endocrinol Metab. 1991 Jul;73(1):93-8.PMID: 2045476 [PubMed - indexed for MEDLINE]Related articles

The use of digital image processing to quantitate angiogenesis induced by basic fibroblast growth factor and transplanted pancreatic islets.

Hayek A, Beattie GM, Lopez AD, Chen P.

Microvasc Res. 1991 Mar;41(2):203-9.PMID: 1711145 [PubMed - indexed for MEDLINE]Related articles