PubMed

Mapping networks of protein-mediated physical interactions between chromatin elements.

Tiwari VK, Baylin SB.

Curr Protoc Mol Biol. 2010 Jan;Chapter 21:Unit 21.16.1-13.PMID: 20069537 [PubMed - indexed for MEDLINE]Related articles

Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes.

Huang Y, Stewart TM, Wu Y, Baylin SB, Marton LJ, Perkins B, Jones RJ, Woster PM, Casero RA Jr.

Clin Cancer Res. 2009 Dec 1;15(23):7217-28. Epub 2009 Nov 24.PMID: 19934284 [PubMed - in process]Related articles

Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection.

Bailey VJ, Keeley BP, Zhang Y, Ho YP, Easwaran H, Brock MV, Pelosky KL, Carraway HE, Baylin SB, Herman JG, Wang TH.

Chembiochem. 2010 Jan 4;11(1):71-4. No abstract available. PMID: 19904794 [PubMed - in process]Related articles

Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation.

Mohammad HP, Cai Y, McGarvey KM, Easwaran H, Van Neste L, Ohm JE, O'Hagan HM, Baylin SB.

Cancer Res. 2009 Aug 1;69(15):6322-30. Epub 2009 Jul 14.PMID: 19602592 [PubMed - indexed for MEDLINE]Related articles

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.

Hellebrekers DM, Lentjes MH, van den Bosch SM, Melotte V, Wouters KA, Daenen KL, Smits KM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker CA, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruïne AP, van Engeland M.

Clin Cancer Res. 2009 Jun 15;15(12):3990-7. Epub 2009 Jun 9.PMID: 19509152 [PubMed - indexed for MEDLINE]Related articles

Breaching the boundaries that safeguard against repression.

Tiwari VK, Baylin SB.

Mol Cell. 2009 May 14;34(4):395-7.PMID: 19481516 [PubMed - indexed for MEDLINE]Related articles

MS-qFRET: a quantum dot-based method for analysis of DNA methylation.

Bailey VJ, Easwaran H, Zhang Y, Griffiths E, Belinsky SA, Herman JG, Baylin SB, Carraway HE, Wang TH.

Genome Res. 2009 Aug;19(8):1455-61. Epub 2009 May 14.PMID: 19443857 [PubMed - indexed for MEDLINE]Related articlesFree article

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers.

Tessema M, Yu YY, Stidley CA, Machida EO, Schuebel KE, Baylin SB, Belinsky SA.

Carcinogenesis. 2009 Jul;30(7):1132-8. Epub 2009 May 12.PMID: 19435948 [PubMed - indexed for MEDLINE]Related articles

Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.

Glöckner SC, Dhir M, Yi JM, McGarvey KE, Van Neste L, Louwagie J, Chan TA, Kleeberger W, de Bruïne AP, Smits KM, Khalid-de Bakker CA, Jonkers DM, Stockbrügger RW, Meijer GA, Oort FA, Iacobuzio-Donahue C, Bierau K, Herman JG, Baylin SB, Van Engeland M, Schuebel KE, Ahuja N.

Cancer Res. 2009 Jun 1;69(11):4691-9. Epub 2009 May 12.PMID: 19435926 [PubMed - indexed for MEDLINE]Related articles

DNA methylation analysis on a droplet-in-oil PCR array.

Zhang Y, Bailey V, Puleo CM, Easwaran H, Griffiths E, Herman JG, Baylin SB, Wang TH.

Lab Chip. 2009 Apr 21;9(8):1059-64. Epub 2009 Mar 6.PMID: 19350087 [PubMed - indexed for MEDLINE]Related articles

PcG proteins, DNA methylation, and gene repression by chromatin looping.

Tiwari VK, McGarvey KM, Licchesi JD, Ohm JE, Herman JG, Schübeler D, Baylin SB.

PLoS Biol. 2008 Dec 2;6(12):2911-27.PMID: 19053175 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.

Yi JM, Tsai HC, Glöckner SC, Lin S, Ohm JE, Easwaran H, James CD, Costello JF, Riggins G, Eberhart CG, Laterra J, Vescovi AL, Ahuja N, Herman JG, Schuebel KE, Baylin SB.

Cancer Res. 2008 Oct 1;68(19):8094-103.PMID: 18829568 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.

Dhir M, Montgomery EA, Glöckner SC, Schuebel KE, Hooker CM, Herman JG, Baylin SB, Gearhart SL, Ahuja N.

J Gastrointest Surg. 2008 Oct;12(10):1745-53. Epub 2008 Aug 21.PMID: 18716850 [PubMed - indexed for MEDLINE]Related articles

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.

O'Hagan HM, Mohammad HP, Baylin SB.

PLoS Genet. 2008 Aug 15;4(8):e1000155.PMID: 18704159 [PubMed - indexed for MEDLINE]Related articlesFree article

Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.

McGarvey KM, Van Neste L, Cope L, Ohm JE, Herman JG, Van Criekinge W, Schuebel KE, Baylin SB.

Cancer Res. 2008 Jul 15;68(14):5753-9.PMID: 18632628 [PubMed - indexed for MEDLINE]Related articlesFree article

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.

Chan TA, Glockner S, Yi JM, Chen W, Van Neste L, Cope L, Herman JG, Velculescu V, Schuebel KE, Ahuja N, Baylin SB.

PLoS Med. 2008 May 27;5(5):e114.PMID: 18507500 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations.

Tiwari VK, Cope L, McGarvey KM, Ohm JE, Baylin SB.

Genome Res. 2008 Jul;18(7):1171-9. Epub 2008 May 23.PMID: 18502945 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation-specific PCR.

Herman JG, Baylin SB.

Curr Protoc Hum Genet. 2001 May;Chapter 10:Unit 10.6.PMID: 18428243 [PubMed - indexed for MEDLINE]Related articles

Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.

Zhang W, Glöckner SC, Guo M, Machida EO, Wang DH, Easwaran H, Van Neste L, Herman JG, Schuebel KE, Watkins DN, Ahuja N, Baylin SB.

Cancer Res. 2008 Apr 15;68(8):2764-72. Erratum in: Cancer Res. 2008 Jul 15;68(14):6030. PMID: 18413743 [PubMed - indexed for MEDLINE]Related articlesFree article

A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.

Ting AH, Suzuki H, Cope L, Schuebel KE, Lee BH, Toyota M, Imai K, Shinomura Y, Tokino T, Baylin SB.

Cancer Res. 2008 Apr 15;68(8):2570-5.PMID: 18413723 [PubMed - indexed for MEDLINE]Related articlesFree article

Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.

Briggs KJ, Corcoran-Schwartz IM, Zhang W, Harcke T, Devereux WL, Baylin SB, Eberhart CG, Watkins DN.

Genes Dev. 2008 Mar 15;22(6):770-85. Erratum in: Genes Dev. 2008 May 15;22(10):1410. PMID: 18347096 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.

Tessema M, Willink R, Do K, Yu YY, Yu W, Machida EO, Brock M, Van Neste L, Stidley CA, Baylin SB, Belinsky SA.

Cancer Res. 2008 Mar 15;68(6):1707-14.PMID: 18339850 [PubMed - indexed for MEDLINE]Related articlesFree article

DNA methylation markers and early recurrence in stage I lung cancer.

Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, Glöckner S, Piantadosi S, Gabrielson E, Pridham G, Pelosky K, Belinsky SA, Yang SC, Baylin SB, Herman JG.

N Engl J Med. 2008 Mar 13;358(11):1118-28.PMID: 18337602 [PubMed - indexed for MEDLINE]Related articles

Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.

Licchesi JD, Westra WH, Hooker CM, Machida EO, Baylin SB, Herman JG.

Carcinogenesis. 2008 May;29(5):895-904. Epub 2008 Feb 28.PMID: 18308762 [PubMed - indexed for MEDLINE]Related articlesFree article

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.

Suzuki H, Toyota M, Carraway H, Gabrielson E, Ohmura T, Fujikane T, Nishikawa N, Sogabe Y, Nojima M, Sonoda T, Mori M, Hirata K, Imai K, Shinomura Y, Baylin SB, Tokino T.

Br J Cancer. 2008 Mar 25;98(6):1147-56. Epub 2008 Feb 19. Erratum in: Br J Cancer. 2008 Jul 22;99(2):384. Caraway, H [corrected to Carraway, H]. PMID: 18283316 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.

Winter JM, Ting AH, Vilardell F, Gallmeier E, Baylin SB, Hruban RH, Kern SE, Iacobuzio-Donahue CA.

Clin Cancer Res. 2008 Jan 15;14(2):412-8.PMID: 18223216 [PubMed - indexed for MEDLINE]Related articlesFree article

Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer.

Riojas MA, Guo M, Glöckner SC, Machida EO, Baylin SB, Ahuja N.

Cancer Biol Ther. 2007 Nov;6(11):1710-6. Epub 2007 Aug 3.PMID: 17986858 [PubMed - indexed for MEDLINE]Related articles

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB.

PLoS Genet. 2007 Sep;3(9):1709-23. Epub 2007 Jul 31.PMID: 17892325 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic biology: the epigenomic era opens.

Baylin SB, Schuebel KE.

Nature. 2007 Aug 2;448(7153):548-9. No abstract available. PMID: 17671496 [PubMed - indexed for MEDLINE]Related articles

DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

McGarvey KM, Greene E, Fahrner JA, Jenuwein T, Baylin SB.

Cancer Res. 2007 Jun 1;67(11):5097-102.PMID: 17545586 [PubMed - indexed for MEDLINE]Related articlesFree article

Cancer as a manifestation of aberrant chromatin structure.

Brock MV, Herman JG, Baylin SB.

Cancer J. 2007 Jan-Feb;13(1):3-8. Review.PMID: 17464240 [PubMed - indexed for MEDLINE]Related articles

Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes.

Huang Y, Greene E, Murray Stewart T, Goodwin AC, Baylin SB, Woster PM, Casero RA Jr.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):8023-8. Epub 2007 Apr 26.PMID: 17463086 [PubMed - indexed for MEDLINE]Related articlesFree article

Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation?

Ohm JE, Baylin SB.

Cell Cycle. 2007 May 2;6(9):1040-3. Epub 2007 May 28. Review.PMID: 17457052 [PubMed - indexed for MEDLINE]Related articlesFree article

A histological survey of green fluorescent protein expression in 'green' mice: implications for stem cell research.

Biankin SA, Collector MI, Biankin AV, Brown LJ, Kleeberger W, Devereux WL, Zahnow CA, Baylin SB, Watkins DN, Sharkis SJ, Leach SD.

Pathology. 2007 Apr;39(2):247-51.PMID: 17454756 [PubMed - indexed for MEDLINE]Related articles

The epigenomics of cancer.

Jones PA, Baylin SB.

Cell. 2007 Feb 23;128(4):683-92. Review.PMID: 17320506 [PubMed - indexed for MEDLINE]Related articles

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB.

Nat Genet. 2007 Feb;39(2):237-42. Epub 2007 Jan 9.PMID: 17211412 [PubMed - indexed for MEDLINE]Related articlesFree article

hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.

Zinn RL, Pruitt K, Eguchi S, Baylin SB, Herman JG.

Cancer Res. 2007 Jan 1;67(1):194-201.PMID: 17210699 [PubMed - indexed for MEDLINE]Related articlesFree article

The cancer epigenome--components and functional correlates.

Ting AH, McGarvey KM, Baylin SB.

Genes Dev. 2006 Dec 1;20(23):3215-31. Review.PMID: 17158741 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.

Singh A, Misra V, Thimmulappa RK, Lee H, Ames S, Hoque MO, Herman JG, Baylin SB, Sidransky D, Gabrielson E, Brock MV, Biswal S.

PLoS Med. 2006 Oct;3(10):e420.PMID: 17020408 [PubMed - indexed for MEDLINE]Related articlesFree article

Delayed diagnosis and elevated mortality in an urban population with HIV and lung cancer: implications for patient care.

Brock MV, Hooker CM, Engels EA, Moore RD, Gillison ML, Alberg AJ, Keruly JC, Yang SC, Heitmiller RF, Baylin SB, Herman JG, Brahmer JR.

J Acquir Immune Defic Syndr. 2006 Sep;43(1):47-55.PMID: 16936558 [PubMed - indexed for MEDLINE]Related articles

Aberrant gene silencing in tumor progression: implications for control of cancer.

Baylin SB, Chen WY.

Cold Spring Harb Symp Quant Biol. 2005;70:427-33. Review.PMID: 16869780 [PubMed - indexed for MEDLINE]Related articles

Hypermethylation of the GATA gene family in esophageal cancer.

Guo M, House MG, Akiyama Y, Qi Y, Capagna D, Harmon J, Baylin SB, Brock MV, Herman JG.

Int J Cancer. 2006 Nov 1;119(9):2078-83.PMID: 16823849 [PubMed - indexed for MEDLINE]Related articles

CIMPle origin for promoter hypermethylation in colorectal cancer?

Schuebel K, Chen W, Baylin SB.

Nat Genet. 2006 Jul;38(7):738-40. No abstract available. PMID: 16804535 [PubMed - indexed for MEDLINE]Related articles

Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer.

Machida EO, Brock MV, Hooker CM, Nakayama J, Ishida A, Amano J, Picchi MA, Belinsky SA, Herman JG, Taniguchi S, Baylin SB.

Cancer Res. 2006 Jun 15;66(12):6210-8. Erratum in: Cancer Res. 2007 Jan 1;67(1):427. PMID: 16778195 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.

Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB.

PLoS Genet. 2006 Mar;2(3):e40. Epub 2006 Mar 31.PMID: 16596166 [PubMed - indexed for MEDLINE]Related articlesFree article

Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.

McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T, Baylin SB.

Cancer Res. 2006 Apr 1;66(7):3541-9.PMID: 16585178 [PubMed - indexed for MEDLINE]Related articlesFree article

Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort.

Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA, Herman JG, Baylin SB, Bunn PA, Byers T.

Cancer Res. 2006 Mar 15;66(6):3338-44.PMID: 16540689 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiostatic activity of DNA methyltransferase inhibitors.

Hellebrekers DM, Jair KW, Viré E, Eguchi S, Hoebers NT, Fraga MF, Esteller M, Fuks F, Baylin SB, van Engeland M, Griffioen AW.

Mol Cancer Ther. 2006 Feb;5(2):467-75.PMID: 16505122 [PubMed - indexed for MEDLINE]Related articlesFree article

Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?

Baylin SB, Ohm JE.

Nat Rev Cancer. 2006 Feb;6(2):107-16. Review.PMID: 16491070 [PubMed - indexed for MEDLINE]Related articles

The fundamental role of epigenetics in hematopoietic malignancies.

Galm O, Herman JG, Baylin SB.

Blood Rev. 2006 Jan;20(1):1-13. Epub 2005 Feb 23. Review.PMID: 16426940 [PubMed - indexed for MEDLINE]Related articles