PubMed

Screening for iron overload: Lessons from the HEmochromatosis and IRon Overload Screening (HEIRS) Study.

Adams P, Barton JC, McLaren GD, Acton RT, Speechley M, McLaren CE, Reboussin DM, Leiendecker-Foster C, Harris EL, Snively BM, Vogt T, Sholinsky P, Thomson E, Dawkins FW, Gordeuk VR, Eckfeldt JH.

Can J Gastroenterol. 2009 Nov;23(11):769-72.PMID: 19893773 [PubMed - in process]Related articlesFree article

Potential Nonresponse Bias in a Clinical Examination After Initial Screening Using Iron Phenotyping and HFE Genotyping in the Hemochromatosis and Iron Overload Screening Study.

Speechley M, Barton JC, Passmore L, Harrison H, Reboussin DM, Harris EL, Rivers CA, Fadojutimi-Akinsiku M, Wenzel L, Diaz S.

Genet Test Mol Biomarkers. 2009 Oct 27. [Epub ahead of print]PMID: 19860558 [PubMed - as supplied by publisher]Related articles

HAMP promoter mutation nc.-153C>T in 785 HEIRS Study participants.

Barton JC, Leiendecker-Foster C, Li H, DelRio-LaFreniere S, Acton RT, Eckfeldt JH; HEIRS Study.

Haematologica. 2009 Oct;94(10):1465; author reply 1465-6. No abstract available. PMID: 19794094 [PubMed - in process]Related articlesFree article

HFE, SLC40A1, HAMP, HJV, TFR2, and FTL mutations detected by denaturing high-performance liquid chromatography after iron phenotyping and HFE C282Y and H63D genotyping in 785 HEIRS Study participants.

Barton JC, Lafreniere SA, Leiendecker-Foster C, Li H, Acton RT, Press RD, Eckfeldt JH.

Am J Hematol. 2009 Nov;84(11):710-4.PMID: 19787796 [PubMed - in process]Related articles

Relationships of serum free thyroxine and erythrocyte measures in euthyroid HFE C282Y homozygotes and control subjects: the HEIRS Study.

Barton JC, Leiendecker-Foster C, Reboussin DM, Adams PC, Acton RT, Eckfeldt JH; FOR THE HEMOCHROMATOSIS AND IRON OVERLOAD SCREENING STUDY RESEARCH INVESTIGATORS.

Int J Lab Hematol. 2009 Aug 25. [Epub ahead of print]PMID: 19706067 [PubMed - as supplied by publisher]Related articles

HFE hemochromatosis and hepatic sarcoid.

Barton JC, McGuire BM, Acton RT.

Am J Med Sci. 2009 May;337(5):386-90.PMID: 19440063 [PubMed - indexed for MEDLINE]Related articles

Differences in hepatic phenotype between hemochromatosis patients with HFE C282Y homozygosity and other HFE genotypes.

Cheng R, Barton JC, Morrison ED, Phatak PD, Krawitt EL, Gordon SC, Kowdley KV.

J Clin Gastroenterol. 2009 Jul;43(6):569-73.PMID: 19359997 [PubMed - indexed for MEDLINE]Related articles

Hemochromatosis and Vibrio vulnificus Wound Infections.

Barton JC, Acton RT.

J Clin Gastroenterol. 2009 Apr 3. [Epub ahead of print]PMID: 19349902 [PubMed - as supplied by publisher]Related articles

A comparison between whites and blacks with severe multi-organ iron overload identified in 16,152 autopsies.

Barton JC, Acton RT, Anderson LE, Alexander CB.

Clin Gastroenterol Hepatol. 2009 Jul;7(7):781-785.e2. Epub 2009 Mar 21.PMID: 19306945 [PubMed - indexed for MEDLINE]Related articles

Hypogonadotrophic hypogonadism due to intrasellar hemangioblastoma in von Hippel-Lindau syndrome.

Barton JC, Goncalves E, Santani A, Chandra-Sekar B, Morris EC, Carter BB, Stolle CA.

Am J Med Genet A. 2009 Mar;149A(3):549-51. No abstract available. PMID: 19215058 [PubMed - indexed for MEDLINE]Related articles

Heme carrier protein 1 (HCP1) genetic variants in the Hemochromatosis and Iron Overload Screening (HEIRS) Study participants.

Wang X, Leiendecker-Foster C, Acton RT, Barton JC, McLaren CE, McLaren GD, Gordeuk VR, Eckfeldt JH.

Blood Cells Mol Dis. 2009 Mar-Apr;42(2):150-4. Epub 2009 Jan 26.PMID: 19176287 [PubMed - indexed for MEDLINE]Related articles

Multi-organ iron overload in an African-American man with ALAS2 R452S and SLC40A1 R561G.

Sussman NL, Lee PL, Dries AM, Schwartz MR, Barton JC.

Acta Haematol. 2008;120(3):168-73. Epub 2008 Dec 10.PMID: 19066423 [PubMed - indexed for MEDLINE]Related articles

Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.

McLaren GD, McLaren CE, Adams PC, Barton JC, Reboussin DM, Gordeuk VR, Acton RT, Harris EL, Speechley MR, Sholinsky P, Dawkins FW, Snively BM, Vogt TM, Eckfeldt JH; Hemochromatosis and Iron Overload Screen (HEIRS) Study Research Investigators.

Can J Gastroenterol. 2008 Nov;22(11):923-30.PMID: 19018338 [PubMed - indexed for MEDLINE]Related articlesFree article

Purification and characterization of sideroblasts from patients with acquired and hereditary sideroblastic anaemia.

Martin FM, Prchal J, Nieva J, Saven A, Andrey J, Bethel K, Barton JC, Aripally G, Bottomley SS, Friedman JS.

Br J Haematol. 2008 Nov;143(3):446-50. Epub 2008 Aug 20. No abstract available. PMID: 18729851 [PubMed - indexed for MEDLINE]Related articlesFree article

Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study.

Adams PC, Reboussin DM, Barton JC, Acton RT, Speechley M, Leiendecker-Foster C, Meenan R, Passmore L, McLaren CE, McLaren GD, Gordeuk V, Dawkins F, Eckfeldt JH.

Int J Lab Hematol. 2008 Aug;30(4):300-5.PMID: 18665827 [PubMed - indexed for MEDLINE]Related articles

Thyroid-stimulating hormone and free thyroxine levels in persons with HFE C282Y homozygosity, a common hemochromatosis genotype: the HEIRS study.

Barton JC, Leiendecker-Foster C, Reboussin DM, Adams PC, Acton RT, Eckfeldt JH; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Thyroid. 2008 Aug;18(8):831-8.PMID: 18651828 [PubMed - indexed for MEDLINE]Related articles

Accuracy of family history of hemochromatosis or iron overload: the hemochromatosis and iron overload screening study.

Acton RT, Barton JC, Passmore LV, Adams PC, McLaren GD, Leiendecker-Foster C, Speechley MR, Harris EL, Castro O, Reiss JA, Snively BM, Harrison BW, McLaren CE.

Clin Gastroenterol Hepatol. 2008 Aug;6(8):934-8. Epub 2008 Jun 27.PMID: 18585964 [PubMed - indexed for MEDLINE]Related articles

5-hydroxytryptamine (5HT)-induced valvulopathy: compositional valvular alterations are associated with 5HT2B receptor and 5HT transporter transcript changes in Sprague-Dawley rats.

Elangbam CS, Job LE, Zadrozny LM, Barton JC, Yoon LW, Gates LD, Slocum N.

Exp Toxicol Pathol. 2008 Aug;60(4-5):253-62. Epub 2008 Jun 3.PMID: 18511249 [PubMed - indexed for MEDLINE]Related articles

Early age-of-onset iron overload and homozygosity for the novel hemojuvelin mutation HJV R54X (exon 3; c.160A-->T) in an African American male of West Indies descent.

Murugan RC, Lee PL, Kalavar MR, Barton JC.

Clin Genet. 2008 Jul;74(1):88-92. Epub 2008 May 19.PMID: 18492090 [PubMed - indexed for MEDLINE]Related articles

Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population.

Gordeuk VR, Reboussin DM, McLaren CE, Barton JC, Acton RT, McLaren GD, Harris EL, Reiss JA, Adams PC, Speechley M, Phatak PD, Sholinsky P, Eckfeldt JH, Chen WP, Passmore L, Dawkins FW.

Am J Hematol. 2008 Aug;83(8):618-26.PMID: 18429050 [PubMed - indexed for MEDLINE]Related articles

Bivariate mixture modeling of transferrin saturation and serum ferritin concentration in Asians, African Americans, Hispanics, and whites in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

McLaren CE, Gordeuk VR, Chen WP, Barton JC, Acton RT, Speechley M, Castro O, Adams PC, Snively BM, Harris EL, Reboussin DM, McLachlan GJ, Bean R; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Transl Res. 2008 Feb;151(2):97-109. Epub 2007 Nov 9.PMID: 18201677 [PubMed - indexed for MEDLINE]Related articles

SLC40A1 c.1402G-->a results in aberrant splicing, ferroportin truncation after glycine 330, and an autosomal dominant hemochromatosis phenotype.

Lee PL, Gelbart T, West C, Barton JC.

Acta Haematol. 2007;118(4):237-41. Epub 2007 Dec 21.PMID: 18160816 [PubMed - indexed for MEDLINE]Related articles

Bilateral subdural hematomas in an adult with hereditary factor VII deficiency: A complication of sit-ups and inversion?

Barton JC, Bertoli LF, O'Malley S.

Clin Appl Thromb Hemost. 2009 Mar-Apr;15(2):242-4. Epub 2007 Dec 26.PMID: 18160563 [PubMed - indexed for MEDLINE]Related articles

Haemochromatosis.

Adams PC, Barton JC.

Lancet. 2007 Dec 1;370(9602):1855-60. Review.PMID: 18061062 [PubMed - indexed for MEDLINE]Related articles

Biological variability of transferrin saturation and unsaturated iron-binding capacity.

Adams PC, Reboussin DM, Press RD, Barton JC, Acton RT, Moses GC, Leiendecker-Foster C, McLaren GD, Dawkins FW, Gordeuk VR, Lovato L, Eckfeldt JH.

Am J Med. 2007 Nov;120(11):999.e1-7.PMID: 17976429 [PubMed - indexed for MEDLINE]Related articlesFree article

HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening.

Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, McLaren GD, Eckfeldt JH, McLaren CE, Reboussin DM, Gordeuk VR, Speechley MR, Reiss JA, Press RD, Dawkins FW; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators.

Genet Test. 2007 Fall;11(3):269-75.PMID: 17949288 [PubMed - indexed for MEDLINE]Related articles

Remission of porphyria cutanea tarda after anastrozole treatment of breast cancer.

Bertoli LF, Barton JC.

Clin Breast Cancer. 2007 Aug;7(9):716-8. Review.PMID: 17919354 [PubMed - indexed for MEDLINE]Related articles

Genetic screening for iron overload: No evidence of discrimination at 1 year.

Hall MA, Barton JC, Adams PC, McLaren CE, Reiss JA, Castro O, Ruggiero A, Acton RT, Power TE, Bent TC.

J Fam Pract. 2007 Oct;56(10):829-34.PMID: 17908514 [PubMed - indexed for MEDLINE]Related articles

Characteristics of participants with self-reported hemochromatosis or iron overload at HEIRS study initial screening.

Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, Eckfeldt JH, McLaren CE, Reiss JA, McLaren GD, Reboussin DM, Gordeuk VR, Speechley MR, Press RD, Dawkins FW; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators.

Am J Hematol. 2008 Feb;83(2):126-32.PMID: 17726683 [PubMed - indexed for MEDLINE]Related articles

African Americans at risk for increased iron stores or liver disease.

Dawkins FW, Gordeuk VR, Snively BM, Lovato L, Barton JC, Acton RT, McLaren GD, Leiendecker-Foster C, McLaren CE, Adams PC, Speechley M, Harris EL, Jackson S, Thomson EJ.

Am J Med. 2007 Aug;120(8):734.e1-9. Epub 2007 Mar 21.PMID: 17679134 [PubMed - indexed for MEDLINE]Related articles

Drug evaluation: Deferitrin for iron overload disorders.

Barton JC.

IDrugs. 2007 Jul;10(7):480-90.PMID: 17642018 [PubMed - indexed for MEDLINE]Related articles

Determinants and characteristics of mean corpuscular volume and hemoglobin concentration in white HFE C282Y homozygotes in the hemochromatosis and iron overload screening study.

McLaren CE, Barton JC, Gordeuk VR, Wu L, Adams PC, Reboussin DM, Speechley M, Chang H, Acton RT, Harris EL, Ruggiero AM, Castro O; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Am J Hematol. 2007 Oct;82(10):898-905.PMID: 17597476 [PubMed - indexed for MEDLINE]Related articles

A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study.

Acton RT, Snively BM, Barton JC, McLaren CE, Adams PC, Rich SS, Eckfeldt JH, Press RD, Sholinsky P, Leiendecker-Foster C, McLaren GD, Speechley MR, Harris EL, Dawkins FW, Gordeuk VR; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Clin Genet. 2007 Jun;71(6):518-29.PMID: 17539901 [PubMed - indexed for MEDLINE]Related articles

SLC40A1 Q248H allele frequencies and Q248H-associated risk of non-HFE iron overload in persons of sub-Saharan African descent.

Barton JC, Acton RT, Lee PL, West C.

Blood Cells Mol Dis. 2007 Sep-Oct;39(2):206-11. Epub 2007 May 9.PMID: 17490902 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum ferritin and transferrin saturation in Asians and Pacific Islanders.

Harris EL, McLaren CE, Reboussin DM, Gordeuk VR, Barton JC, Acton RT, McLaren GD, Vogt TM, Snively BM, Leiendecker-Foster C, Holup JL, Passmore LV, Eckfeldt JH, Lin E, Adams PC.

Arch Intern Med. 2007 Apr 9;167(7):722-6.PMID: 17420432 [PubMed - indexed for MEDLINE]Related articlesFree article

Psychosocial impact of genetic testing for hemochromatosis in the HEIRS Study: a comparison of participants recruited in Canada and in the United States.

Power TE, Adams PC, Barton JC, Acton RT, Howe E, Palla S, Walker AP, Anderson R, Harrison B.

Genet Test. 2007 Spring;11(1):55-64.PMID: 17394393 [PubMed - indexed for MEDLINE]Related articles

Drug evaluation: deferitrin (GT-56-252; NaHBED) for iron overload disorders.

Barton JC.

IDrugs. 2007 Apr;10(4):270-81. Review.PMID: 17390251 [PubMed - indexed for MEDLINE]Related articles

Optimal management strategies for chronic iron overload.

Barton JC.

Drugs. 2007;67(5):685-700. Review.PMID: 17385941 [PubMed - indexed for MEDLINE]Related articles

Chelation therapy for iron overload.

Barton JC.

Curr Gastroenterol Rep. 2007 Mar;9(1):74-82. Review.PMID: 17335681 [PubMed - indexed for MEDLINE]Related articles

Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

Rivers CA, Barton JC, Gordeuk VR, Acton RT, Speechley MR, Snively BM, Leiendecker-Foster C, Press RD, Adams PC, McLaren GD, Dawkins FW, McLaren CE, Reboussin DM.

Blood Cells Mol Dis. 2007 May-Jun;38(3):247-52. Epub 2007 Feb 5.PMID: 17276706 [PubMed - indexed for MEDLINE]Related articles

Hemoglobin binding to A beta and HBG2 SNP association suggest a role in Alzheimer's disease.

Perry RT, Gearhart DA, Wiener HW, Harrell LE, Barton JC, Kutlar A, Kutlar F, Ozcan O, Go RC, Hill WD.

Neurobiol Aging. 2008 Feb;29(2):185-93. Epub 2006 Dec 8.PMID: 17157413 [PubMed - indexed for MEDLINE]Related articlesFree article

Geographic and racial/ethnic differences in HFE mutation frequencies in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

Acton RT, Barton JC, Snively BM, McLaren CE, Adams PC, Harris EL, Speechley MR, McLaren GD, Dawkins FW, Leiendecker-Foster C, Holup JL, Balasubramanyam A; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Ethn Dis. 2006 Autumn;16(4):815-21.PMID: 17061732 [PubMed - indexed for MEDLINE]Related articles

Vibrio vulnificus bacteremia associated with chronic lymphocytic leukemia, hypogammaglobulinemia, and hepatic cirrhosis: relation to host and exposure factors in 252 V. vulnificus infections reported in Louisiana.

Barton JC, Ratard RC.

Am J Med Sci. 2006 Oct;332(4):216-20.PMID: 17031249 [PubMed - indexed for MEDLINE]Related articles

Mixture models of serum iron measures in population screening for hemochromatosis and iron overload.

McLaren CE, Li KT, McLaren GD, Gordeuk VR, Snively BM, Reboussin DM, Barton JC, Acton RT, Dawkins FW, Harris EL, Eckfeldt JH, Moses GC, Adams PC.

Transl Res. 2006 Oct;148(4):196-206.PMID: 17002922 [PubMed - indexed for MEDLINE]Related articles

Evaluation of glycosaminoglycans content and 5-hydroxytryptamine 2B receptor in the heart valves of Sprague-Dawley rats with spontaneous mitral valvulopathy--a possible exacerbation by dl-amphetamine sulfate in Fischer 344 rats?

Elangbam CS, Wehe JG, Barton JC, Krull DL, Nyska A, Crabbs T, Kissling GE.

Exp Toxicol Pathol. 2006 Nov;58(2-3):89-99. Epub 2006 Sep 25.PMID: 16996724 [PubMed - indexed for MEDLINE]Related articles

Relationships of serum ferritin, transferrin saturation, and HFE mutations and self-reported diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS) study.

Acton RT, Barton JC, Passmore LV, Adams PC, Speechley MR, Dawkins FW, Sholinsky P, Reboussin DM, McLaren GD, Harris EL, Bent TC, Vogt TM, Castro O.

Diabetes Care. 2006 Sep;29(9):2084-9.PMID: 16936157 [PubMed - indexed for MEDLINE]Related articlesFree article

Iron overload and prolonged ingestion of iron supplements: clinical features and mutation analysis of hemochromatosis-associated genes in four cases.

Barton JC, Lee PL, West C, Bottomley SS.

Am J Hematol. 2006 Oct;81(10):760-7.PMID: 16838333 [PubMed - indexed for MEDLINE]Related articles

Liver diseases in the hemochromatosis and iron overload screening study.

Adams PC, Passmore L, Chakrabarti S, Reboussin DM, Acton RT, Barton JC, McLaren GD, Eckfeldt JH, Dawkins FW, Gordeuk VR, Harris EL, Leiendecker-Foster C, Gossman E, Sholinsky P; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Clin Gastroenterol Hepatol. 2006 Jul;4(7):918-23; quiz 807.PMID: 16797244 [PubMed - indexed for MEDLINE]Related articles

Disparate phenotypic expression of ALAS2 R452H (nt 1407 G --> A) in two brothers, one with severe sideroblastic anemia and iron overload, hepatic cirrhosis, and hepatocellular carcinoma.

Barton JC, Lee PL.

Blood Cells Mol Dis. 2006 May-Jun;36(3):342-6. Epub 2006 Mar 15.PMID: 16540354 [PubMed - indexed for MEDLINE]Related articles

Effect of Native American ancestry on iron-related phenotypes of Alabama hemochromatosis probands with HFE C282Y homozygosity.

Barton JC, Barton EH, Acton RT.

BMC Med Genet. 2006 Mar 13;7:22.PMID: 16533407 [PubMed - indexed for MEDLINE]Related articlesFree article