Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.
Greaves LC, Preston SL, Tadrous PJ, Taylor RW, Barron MJ, Oukrif D, Leedham SJ, Deheragoda M, Sasieni P, Novelli MR, Jankowski JA, Turnbull DM, Wright NA, McDonald SA.
Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):714-9. Epub 2006 Jan 6.PMID: 16407113 [PubMed - indexed for MEDLINE]Related articlesFree article