PubMed

Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity.

Carr DF, Alfirevic A, Tugwood JD, Barratt BJ, Sherwood J, Smith J, Pirmohamed M, Park BK.

Pharmacogenet Genomics. 2007 Nov;17(11):961-72.PMID: 18075466 [PubMed - indexed for MEDLINE]Related articles

Tacrine-induced liver damage: an analysis of 19 candidate genes.

Alfirevic A, Mills T, Carr D, Barratt BJ, Jawaid A, Sherwood J, Smith JC, Tugwood J, Hartkoorn R, Owen A, Park KB, Pirmohamed M.

Pharmacogenet Genomics. 2007 Dec;17(12):1091-100.PMID: 18004213 [PubMed - indexed for MEDLINE]Related articles

Sequencing and association analysis of the type 1 diabetes-linked region on chromosome 10p12-q11.

Nejentsev S, Smink LJ, Smyth D, Bailey R, Lowe CE, Payne F, Masters J, Godfrey L, Lam A, Burren O, Stevens H, Nutland S, Walker NM, Smith A, Twells R, Barratt BJ, Wright C, French L, Chen Y, Deloukas P, Rogers J, Dunham I, Todd JA.

BMC Genet. 2007 May 17;8:24.PMID: 17509149 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis.

Kindmark A, Jawaid A, Harbron CG, Barratt BJ, Bengtsson OF, Andersson TB, Carlsson S, Cederbrant KE, Gibson NJ, Armstrong M, Lagerström-Fermér ME, Dellsén A, Brown EM, Thornton M, Dukes C, Jenkins SC, Firth MA, Harrod GO, Pinel TH, Billing-Clason SM, Cardon LR, March RE.

Pharmacogenomics J. 2008 Jun;8(3):186-95. Epub 2007 May 15.PMID: 17505501 [PubMed - indexed for MEDLINE]Related articles

Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.

Alfirevic A, Mills T, Harrington P, Pinel T, Sherwood J, Jawaid A, Smith JC, March RE, Barratt BJ, Chadwick DW, Kevin Park B, Pirmohamed M.

Pharmacogenet Genomics. 2006 Apr;16(4):287-96.PMID: 16538175 [PubMed - indexed for MEDLINE]Related articles

Comparison of population- and family-based methods for genetic association analysis in the presence of interacting loci.

Howson JM, Barratt BJ, Todd JA, Cordell HJ.

Genet Epidemiol. 2005 Jul;29(1):51-67.PMID: 15892093 [PubMed - indexed for MEDLINE]Related articles

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans.

Petry CJ, Ong KK, Barratt BJ, Wingate D, Cordell HJ, Ring SM, Pembrey ME, Reik W, Todd JA, Dunger DB; ALSPAC Study Team.

BMC Genet. 2005 May 10;6(1):22.PMID: 15885138 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association studies: theoretical and practical concerns.

Wang WY, Barratt BJ, Clayton DG, Todd JA.

Nat Rev Genet. 2005 Feb;6(2):109-18. Review.PMID: 15716907 [PubMed - indexed for MEDLINE]Related articles

Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics.

Burren OS, Healy BC, Lam AC, Schuilenburg H, Dolman GE, Everett VH, Laneri D, Nutland S, Rance HE, Payne F, Smyth D, Lowe C, Barratt BJ, Twells RC, Rainbow DB, Wicker LS, Todd JA, Walker NM, Smink LJ.

Hum Genomics. 2004 Jan;1(2):98-109.PMID: 15601538 [PubMed - indexed for MEDLINE]Related articles

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.

Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA.

Diabetes. 2004 Nov;53(11):3020-3.PMID: 15504986 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of peptidylglycine alpha-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals.

Barratt BJ, Easton CJ, Henry DJ, Li IH, Radom L, Simpson JS.

J Am Chem Soc. 2004 Oct 20;126(41):13306-11.PMID: 15479085 [PubMed - indexed for MEDLINE]Related articles

Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes.

Hulme JS, Barratt BJ, Twells RC, Cooper JD, Lowe CE, Howson JM, Lam AC, Smink LJ, Savage DA, Undlien DE, Guja C, Ionescu-Tîirgoviste C, Tuomilehto-Wolf E, Tuomilehto J, Todd JA.

Diabetes. 2004 Sep;53(9):2479-82.PMID: 15331563 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping.

Pask R, Rance HE, Barratt BJ, Nutland S, Smyth DJ, Sebastian M, Twells RC, Smith A, Lam AC, Smink LJ, Walker NM, Todd JA.

BMC Biotechnol. 2004 Jul 27;4:15.PMID: 15279678 [PubMed - indexed for MEDLINE]Related articlesFree article

Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

Barratt BJ, Payne F, Lowe CE, Hermann R, Healy BC, Harold D, Concannon P, Gharani N, McCarthy MI, Olavesen MG, McCormack R, Guja C, Ionescu-Tîrgovişte C, Undlien DE, Rønningen KS, Gillespie KM, Tuomilehto-Wolf E, Tuomilehto J, Bennett ST, Clayton DG, Cordell HJ, Todd JA.

Diabetes. 2004 Jul;53(7):1884-9.PMID: 15220214 [PubMed - indexed for MEDLINE]Related articlesFree article

SNP allele frequency estimation in DNA pools and variance components analysis.

Downes K, Barratt BJ, Akan P, Bumpstead SJ, Taylor SD, Clayton DG, Deloukas P.

Biotechniques. 2004 May;36(5):840-5.PMID: 15152604 [PubMed - indexed for MEDLINE]Related articles

Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes.

Vella A, Howson JM, Barratt BJ, Twells RC, Rance HE, Nutland S, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîrgovişte C, Savage DA, Todd JA.

Diabetes. 2004 Apr;53(4):1158-61.PMID: 15047635 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal-fetal interactions and birth order influence insulin variable number of tandem repeats allele class associations with head size at birth and childhood weight gain.

Ong KK, Petry CJ, Barratt BJ, Ring S, Cordell HJ, Wingate DL, Pembrey ME, Todd JA, Dunger DB; Avon Longitudinal Study of Pregnancy and Childhood Study Team.

Diabetes. 2004 Apr;53(4):1128-33.PMID: 15047631 [PubMed - indexed for MEDLINE]Related articlesFree article

Cost-effective analysis of candidate genes using htSNPs: a staged approach.

Lowe CE, Cooper JD, Chapman JM, Barratt BJ, Twells RC, Green EA, Savage DA, Guja C, Ionescu-Tîrgovişte C, Tuomilehto-Wolf E, Tuomilehto J, Todd JA, Clayton DG.

Genes Immun. 2004 Jun;5(4):301-5.PMID: 15029236 [PubMed - indexed for MEDLINE]Related articles

Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects.

Cordell HJ, Barratt BJ, Clayton DG.

Genet Epidemiol. 2004 Apr;26(3):167-85.PMID: 15022205 [PubMed - indexed for MEDLINE]Related articles

Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes.

Eftychi C, Howson JM, Barratt BJ, Vella A, Payne F, Smyth DJ, Twells RC, Walker NM, Rance HE, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîirgovişte C, Savage DA, Todd JA.

Diabetes. 2004 Mar;53(3):870-3.PMID: 14988278 [PubMed - indexed for MEDLINE]Related articlesFree article

Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

Payne F, Smyth DJ, Pask R, Barratt BJ, Cooper JD, Twells RC, Walker NM, Lam AC, Smink LJ, Nutland S, Rance HE, Todd JA.

Diabetes. 2004 Feb;53(2):505-9.PMID: 14747305 [PubMed - indexed for MEDLINE]Related articlesFree article

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

Walter M, Albert E, Conrad M, Keller E, Hummel M, Ferber K, Barratt BJ, Todd JA, Ziegler AG, Bonifacio E.

Diabetologia. 2003 May;46(5):712-20. Epub 2003 May 16.PMID: 12750767 [PubMed - indexed for MEDLINE]Related articles

Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design.

Barratt BJ, Payne F, Rance HE, Nutland S, Todd JA, Clayton DG.

Ann Hum Genet. 2002 Nov;66(Pt 5-6):393-405.PMID: 12485472 [PubMed - indexed for MEDLINE]Related articles

Haplotype tagging for the identification of common disease genes.

Johnson GC, Esposito L, Barratt BJ, Smith AN, Heward J, Di Genova G, Ueda H, Cordell HJ, Eaves IA, Dudbridge F, Twells RC, Payne F, Hughes W, Nutland S, Stevens H, Carr P, Tuomilehto-Wolf E, Tuomilehto J, Gough SC, Clayton DG, Todd JA.

Nat Genet. 2001 Oct;29(2):233-7.PMID: 11586306 [PubMed - indexed for MEDLINE]Related articles

Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation.

Mein CA, Barratt BJ, Dunn MG, Siegmund T, Smith AN, Esposito L, Nutland S, Stevens HE, Wilson AJ, Phillips MS, Jarvis N, Law S, de Arruda M, Todd JA.

Genome Res. 2000 Mar;10(3):330-43.PMID: 10720574 [PubMed - indexed for MEDLINE]Related articlesFree article