PubMed

Effects of formoterol and salmeterol on cytokine release from monocyte-derived macrophages.

Donnelly LE, Tudhope SJ, Fenwick PS, Barnes PJ.

Eur Respir J. 2009 Nov 19. [Epub ahead of print]PMID: 19926732 [PubMed - as supplied by publisher]Related articles

Defective macrophage phagocytosis of bacteria in COPD.

Taylor AE, Finney-Hayward TK, Quint JK, Thomas CM, Tudhope SJ, Wedzicha JA, Barnes PJ, Donnelly LE.

Eur Respir J. 2009 Nov 6. [Epub ahead of print]PMID: 19897561 [PubMed - as supplied by publisher]Related articles

Hypoxia inducible factor 1 alpha (HIF-1{alpha}) induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 (HDAC2) transcription.

Charron CE, Chou PC, Coutts DJ, Kumar V, To M, Akashi K, Pinhu L, Griffiths M, Adcock IM, Barnes PJ, Ito K.

J Biol Chem. 2009 Oct 30. [Epub ahead of print]PMID: 19880520 [PubMed - as supplied by publisher]Related articlesFree article

Expression of TRPC6 Channels in Human Lung Macrophages.

Finney-Hayward TK, Popa O, Bahra P, Li S, Poll CT, Gosling M, Nicholson AG, Russell RE, Kon OM, Jarai G, Westwick J, Barnes PJ, Donnelly LE.

Am J Respir Cell Mol Biol. 2009 Oct 20. [Epub ahead of print]PMID: 19843708 [PubMed - as supplied by publisher]Related articles

Histone deacetylase-2 and airway disease.

Barnes PJ.

Ther Adv Respir Dis. 2009 Oct;3(5):235-43. Epub 2009 Oct 7.PMID: 19812111 [PubMed - in process]Related articles

Nitric Oxide Synthase Isoenzyme Expression and Activity in Peripheral Lungs of COPD Patients.

Brindicci C, Kharitonov SA, Ito M, Elliott MW, Hogg JC, Barnes PJ, Ito K.

Am J Respir Crit Care Med. 2009 Sep 24. [Epub ahead of print]PMID: 19797159 [PubMed - as supplied by publisher]Related articles

Involvement of IL-13 in Tobacco Smoke Induced Changes in the Structure and Function of Rat Intrapulmonary Airways.

Cooper PR, Poll CT, Barnes PJ, Sturton RG.

Am J Respir Cell Mol Biol. 2009 Sep 25. [Epub ahead of print]PMID: 19783789 [PubMed - as supplied by publisher]Related articles

Burden and pathogenesis of chronic obstructive pulmonary disease.

Stockley RA, Mannino D, Barnes PJ.

Proc Am Thorac Soc. 2009 Sep 15;6(6):524-6. Review.PMID: 19741261 [PubMed - in process]Related articlesFree article

MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients.

Caramori G, Casolari P, Di Gregorio C, Saetta M, Baraldo S, Boschetto P, Ito K, Fabbri LM, Barnes PJ, Adcock IM, Cavallesco G, Chung KF, Papi A.

Histopathology. 2009 Sep;55(3):321-31.PMID: 19723147 [PubMed - indexed for MEDLINE]Related articles

The cytokine network in chronic obstructive pulmonary disease.

Barnes PJ.

Am J Respir Cell Mol Biol. 2009 Dec;41(6):631-8. Epub 2009 Aug 28. Review.PMID: 19717810 [PubMed - indexed for MEDLINE]Related articles

New drugs for exacerbations of chronic obstructive pulmonary disease.

Hansel TT, Barnes PJ.

Lancet. 2009 Aug 29;374(9691):744-55. Review.PMID: 19716967 [PubMed - indexed for MEDLINE]Related articles

Chronic obstructive pulmonary disease in non-smokers.

Salvi SS, Barnes PJ.

Lancet. 2009 Aug 29;374(9691):733-43. Review.PMID: 19716966 [PubMed - indexed for MEDLINE]Related articles

Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD.

Di Stefano A, Caramori G, Gnemmi I, Contoli M, Bristot L, Capelli A, Ricciardolo FL, Magno F, D'Anna SE, Zanini A, Carbone M, Sabatini F, Usai C, Brun P, Chung KF, Barnes PJ, Papi A, Adcock IM, Balbi B.

Thorax. 2009 Nov;64(11):968-75. Epub 2009 Aug 23.PMID: 19703829 [PubMed - in process]Related articles

ICS and COPD: time to clear the air.

Ford PA, Russell RE, Barnes PJ.

Int J Chron Obstruct Pulmon Dis. 2009;4:289-90. Epub 2009 Aug 3. No abstract available. PMID: 19684862 [PubMed - in process]Related articlesFree article

Alternative mechanisms for tiotropium.

Bateman ED, Rennard S, Barnes PJ, Dicpinigaitis PV, Gosens R, Gross NJ, Nadel JA, Pfeifer M, Racké K, Rabe KF, Rubin BK, Welte T, Wessler I.

Pulm Pharmacol Ther. 2009 Dec;22(6):533-42. Epub 2009 Jul 25.PMID: 19635581 [PubMed - in process]Related articles

Survivin and COX-2 expression in male breast carcinoma.

Younis T, Haché KD, Rayson D, Dewar R, Gray S, Barnes PJ.

Breast. 2009 Aug;18(4):228-32. Epub 2009 Jul 25.PMID: 19632843 [PubMed - indexed for MEDLINE]Related articles

T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients.

Di Stefano A, Caramori G, Gnemmi I, Contoli M, Vicari C, Capelli A, Magno F, D'Anna SE, Zanini A, Brun P, Casolari P, Chung KF, Barnes PJ, Papi A, Adcock I, Balbi B.

Clin Exp Immunol. 2009 Aug;157(2):316-24.PMID: 19604272 [PubMed - indexed for MEDLINE]Related articles

Inhaled corticosteroids in COPD: the case against.

Suissa S, Barnes PJ.

Eur Respir J. 2009 Jul;34(1):13-6. No abstract available. PMID: 19567599 [PubMed - indexed for MEDLINE]Related articles

Intrinsic asthma: not so different from allergic asthma but driven by superantigens?

Barnes PJ.

Clin Exp Allergy. 2009 Aug;39(8):1145-51. Epub 2009 Jun 15.PMID: 19538350 [PubMed - in process]Related articles

Rescue treatment in asthma. More than as-needed bronchodilation.

Papi A, Caramori G, Adcock IM, Barnes PJ.

Chest. 2009 Jun;135(6):1628-33. Review.PMID: 19497897 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoid resistance in inflammatory diseases.

Barnes PJ, Adcock IM.

Lancet. 2009 May 30;373(9678):1905-17. Review.PMID: 19482216 [PubMed - indexed for MEDLINE]Related articles

Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease.

Maneechotesuwan K, Yao X, Ito K, Jazrawi E, Usmani OS, Adcock IM, Barnes PJ.

PLoS Med. 2009 May 12;6(5):e1000076. Epub 2009 May 19.PMID: 19436703 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2.

Osoata GO, Yamamura S, Ito M, Vuppusetty C, Adcock IM, Barnes PJ, Ito K.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):366-71. Epub 2009 May 3.PMID: 19410558 [PubMed - indexed for MEDLINE]Related articles

Systemic manifestations and comorbidities of COPD.

Barnes PJ, Celli BR.

Eur Respir J. 2009 May;33(5):1165-85. Review.PMID: 19407051 [PubMed - indexed for MEDLINE]Related articles

The airway vasculature: recent advances and clinical implications.

Paredi P, Barnes PJ.

Thorax. 2009 May;64(5):444-50. Review.PMID: 19401490 [PubMed - indexed for MEDLINE]Related articles

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

Nakamaru Y, Vuppusetty C, Wada H, Milne JC, Ito M, Rossios C, Elliot M, Hogg J, Kharitonov S, Goto H, Bemis JE, Elliott P, Barnes PJ, Ito K.

FASEB J. 2009 Sep;23(9):2810-9. Epub 2009 Apr 17.PMID: 19376817 [PubMed - indexed for MEDLINE]Related articles

Bronchodilatory effect of the PPAR-gamma agonist rosiglitazone in smokers with asthma.

Spears M, Donnelly I, Jolly L, Brannigan M, Ito K, McSharry C, Lafferty J, Chaudhuri R, Braganza G, Bareille P, Sweeney L, Adcock IM, Barnes PJ, Wood S, Thomson NC.

Clin Pharmacol Ther. 2009 Jul;86(1):49-53. Epub 2009 Apr 8.PMID: 19357642 [PubMed - indexed for MEDLINE]Related articles

Activation of NF-kappaB transcription factor in asthma death.

Caramori G, Oates T, Nicholson AG, Casolari P, Ito K, Barnes PJ, Papi A, Adcock IM, Chung KF.

Histopathology. 2009 Mar;54(4):507-9. No abstract available. PMID: 19309411 [PubMed - indexed for MEDLINE]Related articles

The acute effect of swimming on airway inflammation in adolescent elite swimmers.

Pedersen L, Lund TK, Mølgaard E, Kharitonov SA, Barnes PJ, Backer V.

J Allergy Clin Immunol. 2009 Feb;123(2):502-4. No abstract available. PMID: 19203664 [PubMed - indexed for MEDLINE]Related articles

Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: a pilot study.

Spears M, Donnelly I, Jolly L, Brannigan M, Ito K, McSharry C, Lafferty J, Chaudhuri R, Braganza G, Adcock IM, Barnes PJ, Wood S, Thomson NC.

Eur Respir J. 2009 May;33(5):1010-7. Epub 2009 Feb 5.PMID: 19196814 [PubMed - indexed for MEDLINE]Related articles

Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine.

Osoata GO, Hanazawa T, Brindicci C, Ito M, Barnes PJ, Kharitonov S, Ito K.

Chest. 2009 Jun;135(6):1513-20. Epub 2009 Feb 2.PMID: 19188555 [PubMed - indexed for MEDLINE]Related articles

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.

Marwick JA, Caramori G, Stevenson CS, Casolari P, Jazrawi E, Barnes PJ, Ito K, Adcock IM, Kirkham PA, Papi A.

Am J Respir Crit Care Med. 2009 Apr 1;179(7):542-8. Epub 2009 Jan 22.PMID: 19164702 [PubMed - indexed for MEDLINE]Related articles

Leukotriene B4 release by human lung macrophages via receptor- not voltage-operated Ca2+ channels.

Finney-Hayward TK, Bahra P, Li S, Poll CT, Nicholson AG, Russell RE, Ford PA, Westwick J, Fenwick PS, Barnes PJ, Donnelly LE.

Eur Respir J. 2009 May;33(5):1105-12. Epub 2009 Jan 22.PMID: 19164358 [PubMed - indexed for MEDLINE]Related articles

Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD.

Cosio BG, Iglesias A, Rios A, Noguera A, Sala E, Ito K, Barnes PJ, Agusti A.

Thorax. 2009 May;64(5):424-9. Epub 2009 Jan 21.PMID: 19158122 [PubMed - indexed for MEDLINE]Related articles

COPD as a disease of accelerated lung aging.

Ito K, Barnes PJ.

Chest. 2009 Jan;135(1):173-80. Review.PMID: 19136405 [PubMed - indexed for MEDLINE]Related articles

A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma.

Wenzel SE, Barnes PJ, Bleecker ER, Bousquet J, Busse W, Dahlén SE, Holgate ST, Meyers DA, Rabe KF, Antczak A, Baker J, Horvath I, Mark Z, Bernstein D, Kerwin E, Schlenker-Herceg R, Lo KH, Watt R, Barnathan ES, Chanez P; T03 Asthma Investigators.

Am J Respir Crit Care Med. 2009 Apr 1;179(7):549-58. Epub 2009 Jan 8.PMID: 19136369 [PubMed - indexed for MEDLINE]Related articles

Emerging pharmacotherapies for COPD.

Barnes PJ.

Chest. 2008 Dec;134(6):1278-86. Review. Erratum in: Chest. 2009 Apr;135(4):1114. PMID: 19059958 [PubMed - indexed for MEDLINE]Related articlesFree article

Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma.

Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes PJ, Wongkajornsilp A.

J Allergy Clin Immunol. 2009 Jan;123(1):239-48. Epub 2008 Dec 5.PMID: 19058839 [PubMed - indexed for MEDLINE]Related articles

Future treatments for chronic obstructive pulmonary disease and its comorbidities.

Barnes PJ.

Proc Am Thorac Soc. 2008 Dec 1;5(8):857-64. Review.PMID: 19017741 [PubMed - indexed for MEDLINE]Related articlesFree article

The cytokine network in asthma and chronic obstructive pulmonary disease.

Barnes PJ.

J Clin Invest. 2008 Nov;118(11):3546-56. Review.PMID: 18982161 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress modulates theophylline effects on steroid responsiveness.

Marwick JA, Wallis G, Meja K, Kuster B, Bouwmeester T, Chakravarty P, Fletcher D, Whittaker PA, Barnes PJ, Ito K, Adcock IM, Kirkham PA.

Biochem Biophys Res Commun. 2008 Dec 19;377(3):797-802. Epub 2008 Oct 23.PMID: 18951874 [PubMed - indexed for MEDLINE]Related articles

Application of the probabilistic approach to reporting breast fine needle aspiration in males.

MacIntosh RF, Merrimen JL, Barnes PJ.

Acta Cytol. 2008 Sep-Oct;52(5):530-4.PMID: 18833813 [PubMed - indexed for MEDLINE]Related articles

Benchmarking of a motion sensing system for medical imaging and radiotherapy.

Barnes PJ, Baldock C, Meikle SR, Fulton RR.

Phys Med Biol. 2008 Oct 21;53(20):5845-57. Epub 2008 Sep 30.PMID: 18827318 [PubMed - indexed for MEDLINE]Related articles

Role of HDAC2 in the pathophysiology of COPD.

Barnes PJ.

Annu Rev Physiol. 2009;71:451-64. Review.PMID: 18817512 [PubMed - indexed for MEDLINE]Related articles

Defective antioxidant gene regulation in COPD: a case for broccoli.

Barnes PJ.

Am J Respir Crit Care Med. 2008 Sep 15;178(6):552-4. No abstract available. PMID: 18755929 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients.

Brindicci C, Ito K, Torre O, Barnes PJ, Kharitonov SA.

Chest. 2009 Feb;135(2):353-67. Epub 2008 Aug 21.PMID: 18719059 [PubMed - indexed for MEDLINE]Related articles

Role of GATA-3 in allergic diseases.

Barnes PJ.

Curr Mol Med. 2008 Aug;8(5):330-4. Review.PMID: 18691059 [PubMed - indexed for MEDLINE]Related articles

Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control.

O'Byrne PM, Naya IP, Kallen A, Postma DS, Barnes PJ.

Chest. 2008 Dec;134(6):1192-9. Epub 2008 Aug 8.PMID: 18689590 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of corticosteroid resistance.

Adcock IM, Barnes PJ.

Chest. 2008 Aug;134(2):394-401. Review.PMID: 18682458 [PubMed - indexed for MEDLINE]Related articlesFree article

Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis.

Lucidi V, Ciabattoni G, Bella S, Barnes PJ, Montuschi P.

Free Radic Biol Med. 2008 Sep 15;45(6):913-9. Epub 2008 Jun 30.PMID: 18634869 [PubMed - indexed for MEDLINE]Related articles