PubMed

A genome-wide association study on African-ancestry populations for asthma.

Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC.

J Allergy Clin Immunol. 2009 Nov 10. [Epub ahead of print]PMID: 19910028 [PubMed - as supplied by publisher]Related articles

Genetic variants in the mannose receptor gene (MRC1) are associated with asthma in two independent populations.

Hattori T, Konno S, Hizawa N, Isada A, Takahashi A, Shimizu K, Shimizu K, Gao P, Beaty TH, Barnes KC, Huang SK, Nishimura M.

Immunogenetics. 2009 Nov 10. [Epub ahead of print]PMID: 19902202 [PubMed - as supplied by publisher]Related articles

Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.

Gao PS, Rafaels NM, Hand T, Murray T, Boguniewicz M, Hata T, Schneider L, Hanifin JM, Gallo RL, Gao L, Beaty TH, Beck LA, Barnes KC, Leung DY.

J Allergy Clin Immunol. 2009 Sep;124(3):507-13, 513.e1-7.PMID: 19733298 [PubMed - indexed for MEDLINE]Related articles

Cytokine modulation of atopic dermatitis filaggrin skin expression.

Howell MD, Kim BE, Gao P, Grant AV, Boguniewicz M, DeBenedetto A, Schneider L, Beck LA, Barnes KC, Leung DY.

J Allergy Clin Immunol. 2009 Sep;124(3 Suppl 2):R7-R12.PMID: 19720210 [PubMed - indexed for MEDLINE]Related articles

Association of G-protein-coupled receptor 154 with asthma and total IgE in a population of the Caribbean coast of Colombia.

Vergara C, Jiménez S, Acevedo N, Martínez B, Mercado D, Gusmão L, Rafaels N, Hand T, Barnes KC, Caraballo L.

Clin Exp Allergy. 2009 Jul 16. [Epub ahead of print]PMID: 19624525 [PubMed - as supplied by publisher]Related articles

Increased prevalence of autoimmunity in patients with white spot syndromes and their family members.

Pearlman RB, Golchet PR, Feldmann MG, Yannuzzi LA, Cooney MJ, Thorne JE, Folk JC, Ryan EH, Agarwal A, Barnes KC, Becker KG, Jampol LM.

Arch Ophthalmol. 2009 Jul;127(7):869-74.PMID: 19597107 [PubMed - indexed for MEDLINE]Related articles

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations.

Price AL, Tandon A, Patterson N, Barnes KC, Rafaels N, Ruczinski I, Beaty TH, Mathias R, Reich D, Myers S.

PLoS Genet. 2009 Jun;5(6):e1000519. Epub 2009 Jun 19.PMID: 19543370 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.

Beck LA, Boguniewicz M, Hata T, Schneider LC, Hanifin J, Gallo R, Paller AS, Lieff S, Reese J, Zaccaro D, Milgrom H, Barnes KC, Leung DY.

J Allergy Clin Immunol. 2009 Aug;124(2):260-9, 269.e1-7. Epub 2009 Jun 27.PMID: 19541356 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST.

Am J Hum Genet. 2009 May;84(5):581-93. Epub 2009 May 7.PMID: 19426955 [PubMed - indexed for MEDLINE]Related articlesFree article

African ancestry is associated with risk of asthma and high total serum IgE in a population from the Caribbean Coast of Colombia.

Vergara C, Caraballo L, Mercado D, Jimenez S, Rojas W, Rafaels N, Hand T, Campbell M, Tsai YJ, Gao L, Duque C, Lopez S, Bedoya G, Ruiz-Linares A, Barnes KC.

Hum Genet. 2009 Jun;125(5-6):565-79. Epub 2009 Mar 17.PMID: 19290544 [PubMed - indexed for MEDLINE]Related articles

Recent advances in genetic predisposition to clinical acute lung injury.

Gao L, Barnes KC.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L713-25. Epub 2009 Feb 13. Review.PMID: 19218355 [PubMed - indexed for MEDLINE]Related articles

Leptin receptor polymorphisms and lung function decline in COPD.

Hansel NN, Gao L, Rafaels NM, Mathias RA, Neptune ER, Tankersley C, Grant AV, Connett J, Beaty TH, Wise RA, Barnes KC.

Eur Respir J. 2009 Jul;34(1):103-10. Epub 2009 Feb 5.PMID: 19196818 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema.

Hersh CP, Hansel NN, Barnes KC, Lomas DA, Pillai SG, Coxson HO, Mathias RA, Rafaels NM, Wise RA, Connett JE, Klanderman BJ, Jacobson FL, Gill R, Litonjua AA, Sparrow D, Reilly JJ, Silverman EK; ICGN Investigators.

Am J Respir Cell Mol Biol. 2009 Sep;41(3):324-31. Epub 2009 Jan 8.PMID: 19131638 [PubMed - indexed for MEDLINE]Related articles

Gene encoding Duffy antigen/receptor for chemokines is associated with asthma and IgE in three populations.

Vergara C, Tsai YJ, Grant AV, Rafaels N, Gao L, Hand T, Stockton M, Campbell M, Mercado D, Faruque M, Dunston G, Beaty TH, Oliveira RR, Ponte EV, Cruz AA, Carvalho E, Araujo MI, Watson H, Schleimer RP, Caraballo L, Nickel RG, Mathias RA, Barnes KC.

Am J Respir Crit Care Med. 2008 Nov 15;178(10):1017-22. Epub 2008 Sep 30.PMID: 18827265 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells.

Cheadle C, Nesterova M, Watkins T, Barnes KC, Hall JC, Rosen A, Becker KG, Cho-Chung YS.

BMC Med Genomics. 2008 Sep 26;1:43.PMID: 18822129 [PubMed]Related articlesFree article

High heritability but uncertain mode of inheritance for total serum IgE level and Schistosoma mansoni infection intensity in a schistosomiasis-endemic Brazilian population.

Grant AV, Araujo MI, Ponte EV, Oliveira RR, Cruz AA, Barnes KC, Beaty TH.

J Infect Dis. 2008 Oct 15;198(8):1227-36.PMID: 18717640 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.

Wurfel MM, Gordon AC, Holden TD, Radella F, Strout J, Kajikawa O, Ruzinski JT, Rona G, Black RA, Stratton S, Jarvik GP, Hajjar AM, Nickerson DA, Rieder M, Sevransky J, Maloney JP, Moss M, Martin G, Shanholtz C, Garcia JG, Gao L, Brower R, Barnes KC, Walley KR, Russell JA, Martin TR.

Am J Respir Crit Care Med. 2008 Oct 1;178(7):710-20. Epub 2008 Jul 17.PMID: 18635889 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

Harris ML, Darrah E, Lam GK, Bartlett SJ, Giles JT, Grant AV, Gao P, Scott WW Jr, El-Gabalawy H, Casciola-Rosen L, Barnes KC, Bathon JM, Rosen A.

Arthritis Rheum. 2008 Jul;58(7):1958-67.PMID: 18576335 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of candidate genes in scleroderma-related pulmonary arterial hypertension.

Grigoryev DN, Mathai SC, Fisher MR, Girgis RE, Zaiman AL, Housten-Harris T, Cheadle C, Gao L, Hummers LK, Champion HC, Garcia JG, Wigley FM, Tuder RM, Barnes KC, Hassoun PM.

Transl Res. 2008 Apr;151(4):197-207. Epub 2008 Feb 1.PMID: 18355767 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of CD4+ T-cell gene expression in allergic subjects using two different microarray platforms.

Hansel NN, Cheadle C, Diette GB, Wright J, Thompson KM, Barnes KC, Georas SN.

Allergy. 2008 Mar;63(3):366-9.PMID: 18269679 [PubMed - indexed for MEDLINE]Related articles

The local and systemic inflammatory transcriptome after acute kidney injury.

Grigoryev DN, Liu M, Hassoun HT, Cheadle C, Barnes KC, Rabb H.

J Am Soc Nephrol. 2008 Mar;19(3):547-58. Epub 2008 Jan 30.PMID: 18235097 [PubMed - indexed for MEDLINE]Related articlesFree article

Host defense genes in asthma and sepsis and the role of the environment.

Gao L, Tsai YJ, Grigoryev DN, Barnes KC.

Curr Opin Allergy Clin Immunol. 2007 Dec;7(6):459-67. Review.PMID: 17989521 [PubMed - indexed for MEDLINE]Related articles

Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations.

Gao L, Flores C, Fan-Ma S, Miller EJ, Moitra J, Moreno L, Wadgaonkar R, Simon B, Brower R, Sevransky J, Tuder RM, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Ye SQ, Barnes KC, Garcia JG.

Transl Res. 2007 Jul;150(1):18-29. Epub 2007 May 25.PMID: 17585860 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine modulation of atopic dermatitis filaggrin skin expression.

Howell MD, Kim BE, Gao P, Grant AV, Boguniewicz M, Debenedetto A, Schneider L, Beck LA, Barnes KC, Leung DY.

J Allergy Clin Immunol. 2007 Jul;120(1):150-5. Epub 2007 May 23.PMID: 17512043 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma.

Gao L, Grant AV, Rafaels N, Stockton-Porter M, Watkins T, Gao P, Chi P, Muñoz M, Watson H, Dunston G, Togias A, Hansel N, Sevransky J, Maloney JP, Moss M, Shanholtz C, Brower R, Garcia JG, Grigoryev DN, Cheadle C, Beaty TH, Mathias RA, Barnes KC.

J Allergy Clin Immunol. 2007 May;119(5):1111-8.PMID: 17472811 [PubMed - indexed for MEDLINE]Related articles

African Americans with asthma: genetic insights.

Barnes KC, Grant AV, Hansel NN, Gao P, Dunston GM.

Proc Am Thorac Soc. 2007 Jan;4(1):58-68. Review.PMID: 17202293 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR2 and TLR4 as Potential Biomarkers of Environmental Particulate Matter Exposed Human Myeloid Dendritic Cells.

Williams MA, Cheadle C, Watkins T, Tailor A, Killedar S, Breysse P, Barnes KC, Georas SN.

Biomark Insights. 2007 May 30;2:226-40.PMID: 19662206 [PubMed - in process]Related articlesFree article

Genomic profiling of kidney ischemia-reperfusion reveals expression of specific alloimmunity-associated genes: Linking "immune" and "nonimmune" injury events.

Grigoryev DN, Liu M, Cheadle C, Barnes KC, Rabb H.

Transplant Proc. 2006 Dec;38(10):3333-6.PMID: 17175265 [PubMed - indexed for MEDLINE]Related articlesFree article

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.

Palomero T, Lim WK, Odom DT, Sulis ML, Real PJ, Margolin A, Barnes KC, O'Neil J, Neuberg D, Weng AP, Aster JC, Sigaux F, Soulier J, Look AT, Young RA, Califano A, Ferrando AA.

Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18261-6. Epub 2006 Nov 17. Erratum in: Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4240. PMID: 17114293 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative linkage genome scan for atopy in a large collection of Caucasian families.

Webb BT, van den Oord E, Akkari A, Wilton S, Ly T, Duff R, Barnes KC, Carlsen K, Gerritsen J, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Blumenthal M, Vestbo J, Middleton L, Helms PJ, Anderson WH, Pillai SG.

Hum Genet. 2007 Mar;121(1):83-92. Epub 2006 Nov 14.PMID: 17103228 [PubMed - indexed for MEDLINE]Related articles

A rapid method for microarray cross platform comparisons using gene expression signatures.

Cheadle C, Becker KG, Cho-Chung YS, Nesterova M, Watkins T, Wood W 3rd, Prabhu V, Barnes KC.

Mol Cell Probes. 2007 Feb;21(1):35-46. Epub 2006 Aug 10.PMID: 16982174 [PubMed - indexed for MEDLINE]Related articles

Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population.

Chi PB, Duggal P, Kao WH, Mathias RA, Grant AV, Stockton ML, Garcia JG, Ingersoll RG, Scott AF, Beaty TH, Barnes KC, Fallin MD.

Genet Epidemiol. 2006 Nov;30(7):609-19.PMID: 16830339 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.

Barnes KC, Grant A, Gao P, Baltadjieva D, Berg T, Chi P, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, Brummet ME, Stockton M, Watkins T, Gao L, Gittens M, Wills-Karp M, Cheadle C, Beck LA, Beaty TH, Becker KG, Garcia JG, Mathias RA.

J Allergy Clin Immunol. 2006 Jul;118(1):70-7. Epub 2006 May 30.PMID: 16815140 [PubMed - indexed for MEDLINE]Related articles

A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q.

Mathias RA, Gao P, Goldstein JL, Wilson AF, Pugh EW, Furbert-Harris P, Dunston GM, Malveaux FJ, Togias A, Barnes KC, Beaty TH, Huang SK.

BMC Genet. 2006 Jun 14;7:38.PMID: 16774684 [PubMed - indexed for MEDLINE]Related articlesFree article

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.

Palomero T, Barnes KC, Real PJ, Glade Bender JL, Sulis ML, Murty VV, Colovai AI, Balbin M, Ferrando AA.

Leukemia. 2006 Jul;20(7):1279-87. Epub 2006 May 11.PMID: 16688224 [PubMed - indexed for MEDLINE]Related articles

Genetic epidemiology of health disparities in allergy and clinical immunology.

Barnes KC.

J Allergy Clin Immunol. 2006 Feb;117(2):243-54; quiz 255-6. Review.PMID: 16461122 [PubMed - indexed for MEDLINE]Related articles

Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.

Gao L, Grant A, Halder I, Brower R, Sevransky J, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Shriver MD, Ingersoll R, Scott AF, Beaty TH, Moitra J, Ma SF, Ye SQ, Barnes KC, Garcia JG.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):487-95. Epub 2006 Jan 6.PMID: 16399953 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p.

Pillai SG, Chiano MN, White NJ, Speer M, Barnes KC, Carlsen K, Gerritsen J, Helms P, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Varsani S, Skelding P, Hauser M, Vance J, Pericak-Vance M, Burns DK, Middleton LT, Brewster SR, Anderson WH, Riley JH.

Eur J Hum Genet. 2006 Mar;14(3):307-16. Erratum in: Eur J Hum Genet. 2007 Jun;15(6):714. PMID: 16391567 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity.

Blumenthal MN, Langefeld CD, Barnes KC, Ober C, Meyers DA, King RA, Beaty TH, Beck SR, Bleecker ER, Rich SS; Collaborative Study on the Genetics of Asthma.

J Allergy Clin Immunol. 2006 Jan;117(1):79-85.PMID: 16387588 [PubMed - indexed for MEDLINE]Related articles

Variants in the gene encoding C3 are associated with asthma and related phenotypes among African Caribbean families.

Barnes KC, Grant AV, Baltadzhieva D, Zhang S, Berg T, Shao L, Zambelli-Weiner A, Anderson W, Nelsen A, Pillai S, Yarnall DP, Dienger K, Ingersoll RG, Scott AF, Fallin MD, Mathias RA, Beaty TH, Garcia JG, Wills-Karp M.

Genes Immun. 2006 Jan;7(1):27-35.PMID: 16355111 [PubMed - indexed for MEDLINE]Related articles

Genetic determinants and ethnic disparities in sepsis-associated acute lung injury.

Barnes KC.

Proc Am Thorac Soc. 2005;2(3):195-201. Review.PMID: 16222037 [PubMed - indexed for MEDLINE]Related articlesFree article

A review of the genetic epidemiology of resistance to parasitic disease and atopic asthma: common variants for common phenotypes?

Barnes KC, Grant AV, Gao P.

Curr Opin Allergy Clin Immunol. 2005 Oct;5(5):379-85. Review.PMID: 16131910 [PubMed - indexed for MEDLINE]Related articles

Inheritance of total serum IgE in the isolated Tangier Island population from Virginia: complexities associated with genealogical depth of pedigrees in segregation analyses.

Mathias RA, Beaty TH, Bailey-Wilson JE, Bickel C, Stockton ML, Barnes KC.

Hum Hered. 2005;59(4):228-38. Epub 2005 Jul 26.PMID: 16093728 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the CD14/-260 polymorphism and house dust endotoxin exposure in the Barbados Asthma Genetics Study.

Zambelli-Weiner A, Ehrlich E, Stockton ML, Grant AV, Zhang S, Levett PN, Beaty TH, Barnes KC.

J Allergy Clin Immunol. 2005 Jun;115(6):1203-9.PMID: 15940135 [PubMed - indexed for MEDLINE]Related articles

Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population.

Gao PS, Mathias RA, Plunkett B, Togias A, Barnes KC, Beaty TH, Huang SK.

J Allergy Clin Immunol. 2005 May;115(5):982-8.PMID: 15867855 [PubMed - indexed for MEDLINE]Related articles

Recombinant gp120, antibodies to the V3 region of gp120, and neural progenitor cells.

Klasse PJ, Barnes KC, Moore JP.

J Infect Dis. 2005 Mar 1;191(5):815-6; author reply 816-8. No abstract available. Erratum in: J Infect Dis. 2005 Apr 15;191(8):1389. PMID: 15688301 [PubMed - indexed for MEDLINE]Related articles

Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury.

Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, Brower RG, Barnes KC, Garcia JG.

Am J Respir Crit Care Med. 2005 Feb 15;171(4):361-70. Epub 2004 Dec 3.PMID: 15579727 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability.

Huang JL, Gao PS, Mathias RA, Yao TC, Chen LC, Kuo ML, Hsu SC, Plunkett B, Togias A, Barnes KC, Stellato C, Beaty TH, Huang SK.

Hum Mol Genet. 2004 Nov 1;13(21):2691-7. Epub 2004 Sep 2.PMID: 15345705 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations.

Barnes KC, Caraballo L, Muñoz M, Zambelli-Weiner A, Ehrlich E, Burki M, Jimenez S, Mathias RA, Stockton ML, Deindl P, Mendoza L, Hershey GK, Nickel R, Wills-Karp M.

Clin Exp Allergy. 2004 May;34(5):736-44.PMID: 15144465 [PubMed - indexed for MEDLINE]Related articles

The genetic association database.

Becker KG, Barnes KC, Bright TJ, Wang SA.

Nat Genet. 2004 May;36(5):431-2. No abstract available. PMID: 15118671 [PubMed - indexed for MEDLINE]Related articles