PubMed

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians.

Traurig M, Mack J, Hanson RL, Ghoussaini M, Meyre D, Knowler WC, Kobes S, Froguel P, Bogardus C, Baier LJ.

Diabetes. 2009 Jul;58(7):1682-9. Epub 2009 Apr 28.PMID: 19401419 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant.

Krakoff J, Ma L, Kobes S, Knowler WC, Hanson RL, Bogardus C, Baier LJ.

Diabetes. 2008 Dec;57(12):3267-72. Epub 2008 Oct 3.PMID: 18835933 [PubMed - indexed for MEDLINE]Related articlesFree article

PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians.

Ma L, Hanson RL, Que LN, Guo Y, Kobes S, Bogardus C, Baier LJ.

Diabetes. 2008 Nov;57(11):3156-60. Epub 2008 Jul 22.PMID: 18647954 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.

Ma L, Hanson RL, Que LN, Mack JL, Franks PW, Infante AM, Kobes S, Bogardus C, Baier LJ.

J Clin Endocrinol Metab. 2008 Sep;93(9):3644-9. Epub 2008 Jul 1.PMID: 18593768 [PubMed - indexed for MEDLINE]Related articlesFree article

The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.

Vimaleswaran KS, Luan J, Andersen G, Muller YL, Wheeler E, Brito EC, O'Rahilly S, Pedersen O, Baier LJ, Knowler WC, Barroso I, Wareham NJ, Loos RJ, Franks PW.

J Appl Physiol. 2008 Oct;105(4):1352-8. Epub 2008 May 8.PMID: 18467552 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals.

Guo T, Hanson RL, Traurig M, Muller YL, Ma L, Mack J, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2007 Dec;56(12):3082-8. Epub 2007 Oct 1.PMID: 17909099 [PubMed - indexed for MEDLINE]Related articlesFree article

A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array.

Hanson RL, Bogardus C, Duggan D, Kobes S, Knowlton M, Infante AM, Marovich L, Benitez D, Baier LJ, Knowler WC.

Diabetes. 2007 Dec;56(12):3045-52. Epub 2007 Sep 10.PMID: 17846125 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians.

Muller YL, Hanson RL, Zimmerman C, Harper I, Sutherland J, Kobes S; International Type 2 Diabetes 1q Consortium, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2007 Dec;56(12):3089-94. Epub 2007 Aug 24.PMID: 17720895 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.

Fu M, Sabra MM, Damcott C, Pollin TI, Ma L, Ott S, Shelton JC, Shi X, Reinhart L, O'Connell J, Mitchell BD, Baier LJ, Shuldiner AR.

Diabetes. 2007 May;56(5):1363-8. Epub 2007 Mar 16.PMID: 17369523 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians.

Traurig M, Hanson RL, Kobes S, Bogardus C, Baier LJ.

Diabetologia. 2007 May;50(5):985-9. Epub 2007 Feb 27.PMID: 17333110 [PubMed - indexed for MEDLINE]Related articles

Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits.

Chu WS, Das SK, Wang H, Chan JC, Deloukas P, Froguel P, Baier LJ, Jia W, McCarthy MI, Ng MC, Damcott C, Shuldiner AR, Zeggini E, Elbein SC.

Diabetes. 2007 Mar;56(3):856-62.PMID: 17327457 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians.

Ma L, Hanson RL, Que LN, Cali AM, Fu M, Mack JL, Infante AM, Kobes S; International Type 2 Diabetes 1q Consortium, Bogardus C, Shuldiner AR, Baier LJ.

Diabetes. 2007 May;56(5):1454-9. Epub 2007 Feb 7.PMID: 17287471 [PubMed - indexed for MEDLINE]Related articlesFree article

CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians.

Guo Y, Traurig M, Ma L, Kobes S, Harper I, Infante AM, Bogardus C, Baier LJ, Prochazka M.

Diabetes. 2006 Dec;55(12):3625-9.PMID: 17130513 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of matrix metalloproteinase 3 (MMP3) in preadipocytes/stromal vascular cells from nonobese nondiabetic versus obese nondiabetic Pima Indians.

Traurig MT, Permana PA, Nair S, Kobes S, Bogardus C, Baier LJ.

Diabetes. 2006 Nov;55(11):3160-5.PMID: 17065356 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.

Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MC, O'Connell JR, Pollin TI, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI; International Type 2 Diabetes 1q Consortium.

Diabetes. 2006 Sep;55(9):2541-8. Erratum in: Diabetes. 2006 Nov;55(11):3197. Kunsun, Xiang [corrected to Xiang, Kunsan]. PMID: 16936202 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex-specific effect of the Val1483Ile polymorphism in the fatty acid synthase gene (FAS) on body mass index and lipid profile in Caucasian children.

Körner A, Ma L, Franks PW, Kiess W, Baier LJ, Stumvoll M, Kovacs P.

Int J Obes (Lond). 2007 Feb;31(2):353-8. Epub 2006 Jun 20.PMID: 16788566 [PubMed - indexed for MEDLINE]Related articles

Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: sample size and power calculations.

Hanson RL, Looker HC, Ma L, Muller YL, Baier LJ, Knowler WC.

Ann Hum Genet. 2006 May;70(Pt 3):332-49.PMID: 16674556 [PubMed - indexed for MEDLINE]Related articles

A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo.

Kovacs P, Stumvoll M, Bogardus C, Hanson RL, Baier LJ.

Diabetes. 2006 May;55(5):1497-503.PMID: 16644711 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

Muller YL, Infante AM, Hanson RL, Love-Gregory L, Knowler W, Bogardus C, Baier LJ.

Diabetes. 2005 Oct;54(10):3035-9.PMID: 16186411 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.

Kovacs P, Ma L, Hanson RL, Franks P, Stumvoll M, Bogardus C, Baier LJ.

Diabetologia. 2005 Nov;48(11):2292-5. Epub 2005 Sep 16.PMID: 16167150 [PubMed - indexed for MEDLINE]Related articles

Increased expression of inflammation-related genes in cultured preadipocytes/stromal vascular cells from obese compared with non-obese Pima Indians.

Nair S, Lee YH, Rousseau E, Cam M, Tataranni PA, Baier LJ, Bogardus C, Permana PA.

Diabetologia. 2005 Sep;48(9):1784-8. Epub 2005 Jul 21.PMID: 16034612 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.

Ma L, Tataranni PA, Hanson RL, Infante AM, Kobes S, Bogardus C, Baier LJ.

Diabetes. 2005 May;54(5):1598-602.PMID: 15855352 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians.

Ma L, Tataranni PA, Bogardus C, Baier LJ.

Diabetes. 2004 Oct;53(10):2696-9.PMID: 15448103 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.

Kovacs P, Harper I, Hanson RL, Infante AM, Bogardus C, Tataranni PA, Baier LJ.

Diabetes. 2004 Jul;53(7):1915-9.PMID: 15220220 [PubMed - indexed for MEDLINE]Related articlesFree article

11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle.

Nair S, Lee YH, Lindsay RS, Walker BR, Tataranni PA, Bogardus C, Baier LJ, Permana PA.

Diabetologia. 2004 Jun;47(6):1088-95. Epub 2004 May 20.PMID: 15156315 [PubMed - indexed for MEDLINE]Related articles

Genetic studies of the etiology of type 2 diabetes in Pima Indians: hunting for pieces to a complicated puzzle.

Baier LJ, Hanson RL.

Diabetes. 2004 May;53(5):1181-6. Review. No abstract available. PMID: 15111484 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the FABP2 promoter affects gene expression: implications for prior association studies.

Formanack ML, Baier LJ.

Diabetologia. 2004 Feb;47(2):349-51. Epub 2003 Dec 10.PMID: 14666368 [PubMed - indexed for MEDLINE]Related articles

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians.

Kovacs P, Hanson RL, Lee YH, Yang X, Kobes S, Permana PA, Bogardus C, Baier LJ.

Diabetes. 2003 Dec;52(12):3005-9.PMID: 14633864 [PubMed - indexed for MEDLINE]Related articlesFree article

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians.

Muller YL, Bogardus C, Beamer BA, Shuldiner AR, Baier LJ.

Diabetes. 2003 Jul;52(7):1864-71.PMID: 12829658 [PubMed - indexed for MEDLINE]Related articlesFree article

Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism.

Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA.

Biochemistry. 2003 Jun 24;42(24):7339-47.PMID: 12809489 [PubMed - indexed for MEDLINE]Related articles

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.

Stefan N, Kovacs P, Stumvoll M, Hanson RL, Lehn-Stefan A, Permana PA, Baier LJ, Tataranni PA, Silver K, Bogardus C.

Diabetes. 2003 Jun;52(6):1544-50.PMID: 12765968 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians.

Kovacs P, Lehn-Stefan A, Stumvoll M, Bogardus C, Baier LJ.

Diabetes. 2003 May;52(5):1292-5.PMID: 12716768 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population.

Lindsay RS, Hanson RL, Wiedrich C, Knowler WC, Bennett PH, Baier LJ.

Diabetes. 2003 Jan;52(1):187-93.PMID: 12502511 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23.

Vardarli I, Baier LJ, Hanson RL, Akkoyun I, Fischer C, Rohmeiss P, Basci A, Bartram CR, Van Der Woude FJ, Janssen B.

Kidney Int. 2002 Dec;62(6):2176-83.PMID: 12427143 [PubMed - indexed for MEDLINE]Related articlesFree article

Currently identified genes affecting insulin resistance are not associated with birth weight in the Pima population.

Lindsay RS, Prochazka M, Baier LJ, Knowler WC, Bogardus C, Hanson RL.

Diabet Med. 2002 Oct;19(10):882-4. No abstract available. PMID: 12358881 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the oxygen-regulated protein 150 gene (ORP150) are associated with insulin resistance in Pima Indians.

Kovacs P, Yang X, Permana PA, Bogardus C, Baier LJ.

Diabetes. 2002 May;51(5):1618-21.PMID: 11978664 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms.

Yang X, Pratley RE, Baier LJ, Horikawa Y, Bell GI, Bogardus C, Permana PA.

Mol Genet Metab. 2001 May;73(1):111-3.PMID: 11350192 [PubMed - indexed for MEDLINE]Related articles

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.

Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C.

J Clin Invest. 2000 Oct;106(7):R69-73.PMID: 11018080 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.

Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI.

Nat Genet. 2000 Oct;26(2):163-75. Erratum in: Nat Genet 2000 Dec;26(4):502. PMID: 11017071 [PubMed - indexed for MEDLINE]Related articles

Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.

Baier LJ, Permana PA, Traurig M, Dobberfuhl A, Wiedrich C, Sutherland J, Thuillez P, Luczy-Bachman G, Hara M, Horikawa Y, Hinokio Y, Hanson RL, Bogardus C.

Diabetes Care. 2000 Mar;23(3):302-4.PMID: 10868855 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in the vitamin D-binding protein (Gc locus) are associated with oral glucose tolerance in nondiabetic Pima Indians.

Baier LJ, Dobberfuhl AM, Pratley RE, Hanson RL, Bogardus C.

J Clin Endocrinol Metab. 1998 Aug;83(8):2993-6.PMID: 9709981 [PubMed - indexed for MEDLINE]Related articlesFree article

Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women.

Baier LJ, Wiedrich C, Hanson RL, Bogardus C.

Diabetes. 1998 Jun;47(6):973-5. No abstract available. PMID: 9604878 [PubMed - indexed for MEDLINE]Related articlesFree article

Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit.

Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA.

J Biomol NMR. 1997 Apr;9(3):213-28.PMID: 9204553 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the human intestinal fatty acid binding protein alters fatty acid transport across Caco-2 cells.

Baier LJ, Bogardus C, Sacchettini JC.

J Biol Chem. 1996 May 3;271(18):10892-6.PMID: 8631905 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of lipids in development of noninsulin-dependent diabetes mellitus: lessons learned from Pima Indians.

Tataranni PA, Baier LJ, Paolisso G, Howard BV, Ravussin E.

Lipids. 1996 Mar;31 Suppl:S267-70.PMID: 8729131 [PubMed - indexed for MEDLINE]Related articles

Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians.

Prochazka M, Mochizuki H, Baier LJ, Cohen PT, Bogardus C.

Diabetologia. 1995 Apr;38(4):461-6.PMID: 7796987 [PubMed - indexed for MEDLINE]Related articles

An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.

Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tataranni PA, Mochizuki H, Bennett PH, Bogardus C, Prochazka M.

J Clin Invest. 1995 Mar;95(3):1281-7.PMID: 7883976 [PubMed - indexed for MEDLINE]Related articlesFree article

The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon-induced protein kinase, PKR.

Baier LJ, Shors T, Shors ST, Jacobs BL.

Nucleic Acids Res. 1993 Oct 11;21(20):4830-5.PMID: 7694235 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain.

Baier LJ, Hannibal MC, Hanley EW, Nabel GJ.

Blood. 1991 Aug 15;78(4):1047-55.PMID: 1678287 [PubMed - indexed for MEDLINE]Related articlesFree article