PubMed

Up-regulation of Na+ and Ca2+ transporters in arterial smooth muscle from ouabain hypertensive rats.

Pulina MV, Zulian A, Berra-Romani R, Beskina O, Mazzocco-Spezzia A, Baryshnikov SG, Papparella I, Hamlyn JM, Blaustein MP, Golovina VA.

Am J Physiol Heart Circ Physiol. 2009 Nov 6. [Epub ahead of print]PMID: 19897708 [PubMed - as supplied by publisher]Related articles

Low-dose ouabain constricts small arteries from ouabain-hypertensive rats: implications for sustained elevation of vascular resistance.

Zhang J, Hamlyn JM, Karashima E, Raina H, Mauban JR, Izuka M, Berra-Romani R, Zulian A, Wier WG, Blaustein MP.

Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1140-50. Epub 2009 Jul 17.PMID: 19617413 [PubMed - indexed for MEDLINE]Related articles

The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension.

Blaustein MP, Zhang J, Chen L, Song H, Raina H, Kinsey SP, Izuka M, Iwamoto T, Kotlikoff MI, Lingrel JB, Philipson KD, Wier WG, Hamlyn JM.

Hypertension. 2009 Feb;53(2):291-8. Epub 2008 Dec 22. Review. No abstract available. PMID: 19104005 [PubMed - indexed for MEDLINE]Related articles

Chronic ouabain treatment induces vasa recta endothelial dysfunction in the rat.

Cao C, Payne K, Lee-Kwon W, Zhang Z, Lim SW, Hamlyn J, Blaustein MP, Kwon HM, Pallone TL.

Am J Physiol Renal Physiol. 2009 Jan;296(1):F98-F106. Epub 2008 Oct 22.PMID: 18945826 [PubMed - indexed for MEDLINE]Related articles

Getting a grip on calcium regulation.

Blaustein MP, Charpentier TH, Weber DJ.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18349-50. Epub 2007 Nov 14. No abstract available. PMID: 18003903 [PubMed - indexed for MEDLINE]Related articlesFree article

Local sodium, global reach: filling the gap between salt and hypertension.

Blaustein MP, Wier WG.

Circ Res. 2007 Nov 9;101(10):959-61. No abstract available. PMID: 17991887 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+/Ca2+ exchange inhibitors: a new class of calcium regulators.

Iwamoto T, Watanabe Y, Kita S, Blaustein MP.

Cardiovasc Hematol Disord Drug Targets. 2007 Sep;7(3):188-98. Review.PMID: 17896959 [PubMed - indexed for MEDLINE]Related articles

Sodium pumps: ouabain, ion transport, and signaling in hypertension.

Blaustein MP, Hamlyn JM, Pallone TL.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F438; author reply F439. No abstract available. PMID: 17616574 [PubMed - indexed for MEDLINE]Related articlesFree article

Directionality in drug action on sodium-calcium exchange.

Noble D, Blaustein MP.

Ann N Y Acad Sci. 2007 Mar;1099:540-3.PMID: 17446499 [PubMed - indexed for MEDLINE]Related articles

Preparation of primary cultured mesenteric artery smooth muscle cells for fluorescent imaging and physiological studies.

Golovina VA, Blaustein MP.

Nat Protoc. 2006;1(6):2681-7.PMID: 17406524 [PubMed - indexed for MEDLINE]Related articles

Role of Cav1.2 L-type Ca2+ channels in vascular tone: effects of nifedipine and Mg2+.

Zhang J, Berra-Romani R, Sinnegger-Brauns MJ, Striessnig J, Blaustein MP, Matteson DR.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H415-25. Epub 2006 Sep 15.PMID: 16980345 [PubMed - indexed for MEDLINE]Related articlesFree article

Local subplasma membrane Ca2+ signals detected by a tethered Ca2+ sensor.

Lee MY, Song H, Nakai J, Ohkura M, Kotlikoff MI, Kinsey SP, Golovina VA, Blaustein MP.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13232-7. Epub 2006 Aug 21.PMID: 16924099 [PubMed - indexed for MEDLINE]Related articlesFree article

An N-terminal sequence targets and tethers Na+ pump alpha2 subunits to specialized plasma membrane microdomains.

Song H, Lee MY, Kinsey SP, Weber DJ, Blaustein MP.

J Biol Chem. 2006 May 5;281(18):12929-40. Epub 2006 Mar 8.PMID: 16524882 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms linking sodium to hypertension: report of a symposium.

Hamilton BP, Blaustein MP.

J Investig Med. 2006 Mar;54(2):86-94.PMID: 16472478 [PubMed - indexed for MEDLINE]Related articles

How does salt retention raise blood pressure?

Blaustein MP, Zhang J, Chen L, Hamilton BP.

Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R514-23. Review.PMID: 16467498 [PubMed - indexed for MEDLINE]Related articles

On the mechanism of myogenic tone in small arteries.

Blaustein MP, Zhang J, Wier WG.

J Muscle Res Cell Motil. 2004;25(8):615. No abstract available. PMID: 16285030 [PubMed - indexed for MEDLINE]Related articles

Sodium pump alpha2 subunits control myogenic tone and blood pressure in mice.

Zhang J, Lee MY, Cavalli M, Chen L, Berra-Romani R, Balke CW, Bianchi G, Ferrari P, Hamlyn JM, Iwamoto T, Lingrel JB, Matteson DR, Wier WG, Blaustein MP.

J Physiol. 2005 Nov 15;569(Pt 1):243-56. Epub 2005 Sep 15.PMID: 16166162 [PubMed - indexed for MEDLINE]Related articlesFree article

TTX-sensitive voltage-gated Na+ channels are expressed in mesenteric artery smooth muscle cells.

Berra-Romani R, Blaustein MP, Matteson DR.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H137-45.PMID: 15961372 [PubMed - indexed for MEDLINE]Related articlesFree article

Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle.

Iwamoto T, Kita S, Zhang J, Blaustein MP, Arai Y, Yoshida S, Wakimoto K, Komuro I, Katsuragi T.

Nat Med. 2004 Nov;10(11):1193-9. Epub 2004 Oct 10.PMID: 15475962 [PubMed - indexed for MEDLINE]Related articles

Sex, digitalis, and the sodium pump.

Blaustein MP, Robinson SW, Gottlieb SS, Balke CW, Hamlyn JM.

Mol Interv. 2003 Mar;3(2):68-72, 50. Review.PMID: 14993426 [PubMed - indexed for MEDLINE]Related articlesFree article

Ca2+-sensing transgenic mice: postsynaptic signaling in smooth muscle.

Ji G, Feldman ME, Deng KY, Greene KS, Wilson J, Lee JC, Johnston RC, Rishniw M, Tallini Y, Zhang J, Wier WG, Blaustein MP, Xin HB, Nakai J, Kotlikoff MI.

J Biol Chem. 2004 May 14;279(20):21461-8. Epub 2004 Feb 29.PMID: 14990564 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.

Lencesova L, O'Neill A, Resneck WG, Bloch RJ, Blaustein MP.

J Biol Chem. 2004 Jan 23;279(4):2885-93. Epub 2003 Oct 30.PMID: 14593108 [PubMed - indexed for MEDLINE]Related articlesFree article

Na/Ca exchanger and PMCA localization in neurons and astrocytes: functional implications.

Blaustein MP, Juhaszova M, Golovina VA, Church PJ, Stanley EF.

Ann N Y Acad Sci. 2002 Nov;976:356-66. Review.PMID: 12502582 [PubMed - indexed for MEDLINE]Related articles

Mg2+ blocks myogenic tone but not K+-induced constriction: role for SOCs in small arteries.

Zhang J, Wier WG, Blaustein MP.

Am J Physiol Heart Circ Physiol. 2002 Dec;283(6):H2692-705. Epub 2002 Aug 15.PMID: 12388301 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+ pump alpha 2-subunit expression modulates Ca2+ signaling.

Golovina VA, Song H, James PF, Lingrel JB, Blaustein MP.

Am J Physiol Cell Physiol. 2003 Feb;284(2):C475-86. Epub 2002 Oct 3.PMID: 12388076 [PubMed - indexed for MEDLINE]Related articlesFree article

Organization of Ca2+ stores in vascular smooth muscle: functional implications.

Blaustein MP, Golovina VA, Song H, Choate J, Lencesova L, Robinson SW, Wier WG.

Novartis Found Symp. 2002;246:125-37; discussion 137-41, 221-7. Review.PMID: 12164305 [PubMed - indexed for MEDLINE]Related articles

Structural complexity and functional diversity of endoplasmic reticulum Ca(2+) stores.

Blaustein MP, Golovina VA.

Trends Neurosci. 2001 Oct;24(10):602-8. Review.PMID: 11576675 [PubMed - indexed for MEDLINE]Related articles

Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A).

Ellis KC, Tenenholz TC, Jerng H, Hayhurst M, Dudlak CS, Gilly WF, Blaustein MP, Weber DJ.

Biochemistry. 2001 May 22;40(20):5942-53.PMID: 11352729 [PubMed - indexed for MEDLINE]Related articles

Ouabain augments Ca(2+) transients in arterial smooth muscle without raising cytosolic Na(+).

Arnon A, Hamlyn JM, Blaustein MP.

Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H679-91.PMID: 10924067 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural determinants of scorpion toxin affinity: the charybdotoxin (alpha-KTX) family of K(+)-channel blocking peptides.

Tenenholz TC, Klenk KC, Matteson DR, Blaustein MP, Weber DJ.

Rev Physiol Biochem Pharmacol. 2000;140:135-85. Review. No abstract available. PMID: 10857399 [PubMed - indexed for MEDLINE]Related articles

Unloading and refilling of two classes of spatially resolved endoplasmic reticulum Ca(2+) stores in astrocytes.

Golovina VA, Blaustein MP.

Glia. 2000 Jul;31(1):15-28.PMID: 10816603 [PubMed - indexed for MEDLINE]Related articles

Location of calcium transporters at presynaptic terminals.

Juhaszova M, Church P, Blaustein MP, Stanley EF.

Eur J Neurosci. 2000 Mar;12(3):839-46.PMID: 10762313 [PubMed - indexed for MEDLINE]Related articles

Regulatory processes on the cytoplasmic surface of the Na(+)/Ca(2+) exchanger from lobster exoskeletal muscle.

Eisenrauch A, Juhaszova M, Blaustein MP.

J Membr Biol. 2000 Apr 1;174(3):225-35.PMID: 10758176 [PubMed - indexed for MEDLINE]Related articles

Structural and functional differences of two toxins from the scorpion Pandinus imperator.

Klenk KC, Tenenholz TC, Matteson DR, Rogowski RS, Blaustein MP, Weber DJ.

Proteins. 2000 Mar 1;38(4):441-9.PMID: 10707030 [PubMed - indexed for MEDLINE]Related articles

Na(+) entry via store-operated channels modulates Ca(2+) signaling in arterial myocytes.

Arnon A, Hamlyn JM, Blaustein MP.

Am J Physiol Cell Physiol. 2000 Jan;278(1):C163-73.PMID: 10644524 [PubMed - indexed for MEDLINE]Related articlesFree article

Local and cellular Ca2+ transients in smooth muscle of pressurized rat resistance arteries during myogenic and agonist stimulation.

Miriel VA, Mauban JR, Blaustein MP, Wier WG.

J Physiol. 1999 Aug 1;518 ( Pt 3):815-24.PMID: 10420017 [PubMed - indexed for MEDLINE]Related articlesFree article

Sodium/calcium exchange: its physiological implications.

Blaustein MP, Lederer WJ.

Physiol Rev. 1999 Jul;79(3):763-854. Review.PMID: 10390518 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity of mitochondrial matrix free ca2+: resolution of Ca2+ dynamics in individual mitochondria in situ.

Monteith GR, Blaustein MP.

Am J Physiol. 1999 May;276(5 Pt 1):C1193-204.PMID: 10329969 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha).

Juhng KN, Kokate TG, Yamaguchi S, Kim BY, Rogowski RS, Blaustein MP, Rogawski MA.

Epilepsy Res. 1999 Apr;34(2-3):177-86.PMID: 10210033 [PubMed - indexed for MEDLINE]Related articles

Physiological effects of Na+/Ca2+ exchanger knockdown by antisense oligodeoxynucleotides in arterial myocytes.

Slodzinski MK, Blaustein MP.

Am J Physiol. 1998 Jul;275(1 Pt 1):C251-9.PMID: 9688856 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+/Ca2+ exchange in neonatal rat heart cells: antisense inhibition and protein half-life.

Slodzinski MK, Blaustein MP.

Am J Physiol. 1998 Aug;275(2 Pt 1):C459-67.PMID: 9688600 [PubMed - indexed for MEDLINE]Related articlesFree article

The cellular mechanism of action of cardiotonic steroids: a new hypothesis.

Blaustein MP, Juhaszova M, Golovina VA.

Clin Exp Hypertens. 1998 Jul-Aug;20(5-6):691-703. Review.PMID: 9682925 [PubMed - indexed for MEDLINE]Related articles

Different effects of low and high dose cardiotonic steroids on cytosolic calcium in spontaneously active hippocampal neurons and in co-cultured glia.

Monteith GR, Blaustein MP.

Brain Res. 1998 Jun 8;795(1-2):325-40.PMID: 9622665 [PubMed - indexed for MEDLINE]Related articles

Distinct distribution of different Na+ pump alpha subunit isoforms in plasmalemma. Physiological implications.

Juhaszova M, Blaustein MP.

Ann N Y Acad Sci. 1997 Nov 3;834:524-36. No abstract available. PMID: 9405854 [PubMed - indexed for MEDLINE]Related articles

Scorpion toxin block of the early K+ current (IKf) in rat dorsal root ganglion neurones.

Matteson DR, Blaustein MP.

J Physiol. 1997 Sep 1;503 ( Pt 2):285-301.PMID: 9306273 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal calcium homeostasis in astrocytes from the trisomy 16 mouse.

Bambrick LL, Golovina VA, Blaustein MP, Yarowsky PJ, Krueger BK.

Glia. 1997 Apr;19(4):352-8.PMID: 9097079 [PubMed - indexed for MEDLINE]Related articles

Spatially and functionally distinct Ca2+ stores in sarcoplasmic and endoplasmic reticulum.

Golovina VA, Blaustein MP.

Science. 1997 Mar 14;275(5306):1643-8.PMID: 9054358 [PubMed - indexed for MEDLINE]Related articlesFree article

Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.

Tenenholz TC, Rogowski RS, Collins JH, Blaustein MP, Weber DJ.

Biochemistry. 1997 Mar 11;36(10):2763-71.PMID: 9062103 [PubMed - indexed for MEDLINE]Related articles

Na+ pump low and high ouabain affinity alpha subunit isoforms are differently distributed in cells.

Juhaszova M, Blaustein MP.

Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1800-5.PMID: 9050859 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of La3+ to distinguish activity of the plasmalemmal Ca2+ pump from Na+/Ca2+ exchange in arterial myocytes.

Shimizu H, Borin ML, Blaustein MP.

Cell Calcium. 1997 Jan;21(1):31-41.PMID: 9056075 [PubMed - indexed for MEDLINE]Related articles