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Vitamin D and immune function: understanding common pathways.

Bikle DD.

Curr Osteoporos Rep. 2009 Jul;7(2):58-63.PMID: 19631030 [PubMed - indexed for MEDLINE]Related articles

Quantification of the vitamin D receptor-coregulator interaction.

Teichert A, Arnold LA, Otieno S, Oda Y, Augustinaite I, Geistlinger TR, Kriwacki RW, Guy RK, Bikle DD.

Biochemistry. 2009 Feb 24;48(7):1454-61.PMID: 19183053 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation.

Xie Z, Chang SM, Pennypacker SD, Liao EY, Bikle DD.

Mol Biol Cell. 2009 Mar;20(6):1695-704. Epub 2009 Jan 21.PMID: 19158393 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review.

Pao VY, Chang S, Shoback DM, Bikle DD.

J Bone Miner Res. 2009 Jun;24(6):1135-9.PMID: 19113910 [PubMed - indexed for MEDLINE]Related articles

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

Oda Y, Uchida Y, Moradian S, Crumrine D, Elias PM, Bikle DD.

J Invest Dermatol. 2009 Jun;129(6):1367-78. Epub 2008 Dec 4.PMID: 19052561 [PubMed - indexed for MEDLINE]Related articles

Vitamin D receptor, UVR, and skin cancer: a potential protective mechanism.

Bikle DD.

J Invest Dermatol. 2008 Oct;128(10):2357-61.PMID: 18787544 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin D and the immune system: role in protection against bacterial infection.

Bikle DD.

Curr Opin Nephrol Hypertens. 2008 Jul;17(4):348-52. Review.PMID: 18660668 [PubMed - indexed for MEDLINE]Related articles

Growth hormone/insulin-like growth factor-1/PTH axis in bone.

Bikle DD.

J Bone Miner Res. 2008 May;23(5):581-3. Review. No abstract available. PMID: 18433295 [PubMed - indexed for MEDLINE]Related articles

Integrins, insulin like growth factors, and the skeletal response to load.

Bikle DD.

Osteoporos Int. 2008 Sep;19(9):1237-46. Epub 2008 Mar 29. Review.PMID: 18373051 [PubMed - indexed for MEDLINE]Related articles

Vitamin D insufficiency/deficiency in gastrointestinal disorders.

Bikle DD.

J Bone Miner Res. 2007 Dec;22 Suppl 2:V50-4. Review.PMID: 18290722 [PubMed - indexed for MEDLINE]Related articles

Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes.

Tu CL, Chang W, Xie Z, Bikle DD.

J Biol Chem. 2008 Feb 8;283(6):3519-28. Epub 2007 Dec 7.PMID: 18065418 [PubMed - indexed for MEDLINE]Related articlesFree article

Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.

Schauber J, Oda Y, Büchau AS, Yun QC, Steinmeyer A, Zügel U, Bikle DD, Gallo RL.

J Invest Dermatol. 2008 Apr;128(4):816-24. Epub 2007 Oct 18.PMID: 17943182 [PubMed - indexed for MEDLINE]Related articlesFree article

What is new in vitamin D: 2006-2007.

Bikle DD.

Curr Opin Rheumatol. 2007 Jul;19(4):383-8. Review.PMID: 17551371 [PubMed - indexed for MEDLINE]Related articles

IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone.

Wang Y, Nishida S, Boudignon BM, Burghardt A, Elalieh HZ, Hamilton MM, Majumdar S, Halloran BP, Clemens TL, Bikle DD.

J Bone Miner Res. 2007 Sep;22(9):1329-37.PMID: 17539737 [PubMed - indexed for MEDLINE]Related articles

Constitutive activity of the osteoblast Ca2+-sensing receptor promotes loss of cancellous bone.

Dvorak MM, Chen TH, Orwoll B, Garvey C, Chang W, Bikle DD, Shoback DM.

Endocrinology. 2007 Jul;148(7):3156-63. Epub 2007 Apr 5.PMID: 17412806 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading.

Boudignon BM, Bikle DD, Kurimoto P, Elalieh H, Nishida S, Wang Y, Burghardt A, Majumdar S, Orwoll BE, Rosen C, Halloran BP.

J Appl Physiol. 2007 Jul;103(1):125-31. Epub 2007 Apr 5.PMID: 17412794 [PubMed - indexed for MEDLINE]Related articlesFree article

Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.

Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle DD, Modlin RL, Gallo RL.

J Clin Invest. 2007 Mar;117(3):803-11. Epub 2007 Feb 8.PMID: 17290304 [PubMed - indexed for MEDLINE]Related articlesFree article

The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation.

Xie Z, Bikle DD.

J Biol Chem. 2007 Mar 23;282(12):8695-703. Epub 2007 Jan 22.PMID: 17242406 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation.

Oda Y, Ishikawa MH, Hawker NP, Yun QC, Bikle DD.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):776-80. Epub 2007 Jan 16.PMID: 17223341 [PubMed - indexed for MEDLINE]Related articles

The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes.

Tu CL, Chang W, Bikle DD.

J Invest Dermatol. 2007 May;127(5):1074-83. Epub 2006 Nov 23.PMID: 17124506 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3.

Hawker NP, Pennypacker SD, Chang SM, Bikle DD.

J Invest Dermatol. 2007 Apr;127(4):874-80. Epub 2006 Nov 2.PMID: 17082781 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of IGF-I signaling in regulating osteoclastogenesis.

Wang Y, Nishida S, Elalieh HZ, Long RK, Halloran BP, Bikle DD.

J Bone Miner Res. 2006 Sep;21(9):1350-8.PMID: 16939393 [PubMed - indexed for MEDLINE]Related articles

Insulin-like growth factor-I is essential for embryonic bone development.

Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD.

Endocrinology. 2006 Oct;147(10):4753-61. Epub 2006 Jul 20.PMID: 16857753 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I.

Wang Y, Sakata T, Elalieh HZ, Munson SJ, Burghardt A, Majumdar S, Halloran BP, Bikle DD.

J Endocrinol. 2006 May;189(2):279-87.PMID: 16648295 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and progression of alopecia in the vitamin D receptor null mouse.

Bikle DD, Elalieh H, Chang S, Xie Z, Sundberg JP.

J Cell Physiol. 2006 May;207(2):340-53.PMID: 16419036 [PubMed - indexed for MEDLINE]Related articles

Hairless suppresses vitamin D receptor transactivation in human keratinocytes.

Xie Z, Chang S, Oda Y, Bikle DD.

Endocrinology. 2006 Jan;147(1):314-23. Epub 2005 Nov 3.PMID: 16269453 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin D and skin cancer: a problem in gene regulation.

Bikle DD, Oda Y, Xie Z.

J Steroid Biochem Mol Biol. 2005 Oct;97(1-2):83-91. Epub 2005 Jul 21. Review.PMID: 16039846 [PubMed - indexed for MEDLINE]Related articles

Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1.

Xie Z, Singleton PA, Bourguignon LY, Bikle DD.

Mol Biol Cell. 2005 Jul;16(7):3236-46. Epub 2005 May 4.PMID: 15872086 [PubMed - indexed for MEDLINE]Related articlesFree article

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.

Tu CL, Chang W, Bikle DD.

J Invest Dermatol. 2005 Jan;124(1):187-97.PMID: 15654973 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin D and skin cancer.

Bikle DD.

J Nutr. 2004 Dec;134(12 Suppl):3472S-3478S. Review.PMID: 15570056 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation.

Bikle DD, Oda Y, Xie Z.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):355-60. Review.PMID: 15225800 [PubMed - indexed for MEDLINE]Related articles

Mice lacking 25OHD 1alpha-hydroxylase demonstrate decreased epidermal differentiation and barrier function.

Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):347-53.PMID: 15225799 [PubMed - indexed for MEDLINE]Related articles

Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation.

Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):273-6.PMID: 15225784 [PubMed - indexed for MEDLINE]Related articles

The role of the calcium-sensing receptor in epidermal differentiation.

Tu CL, Oda Y, Komuves L, Bikle DD.

Cell Calcium. 2004 Mar;35(3):265-73. Review.PMID: 15200150 [PubMed - indexed for MEDLINE]Related articles

The effect of LXR activators on AP-1 proteins in keratinocytes.

Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR.

J Invest Dermatol. 2004 Jul;123(1):41-8.PMID: 15191540 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin D regulated keratinocyte differentiation.

Bikle DD.

J Cell Biochem. 2004 Jun 1;92(3):436-44. Review.PMID: 15156556 [PubMed - indexed for MEDLINE]Related articles

25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis.

Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM.

J Invest Dermatol. 2004 Apr;122(4):984-92.PMID: 15102089 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways.

Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, Bikle DD.

J Bone Miner Res. 2004 Mar;19(3):436-46. Epub 2003 Dec 22.PMID: 15040832 [PubMed - indexed for MEDLINE]Related articles

PTH differentially regulates expression of RANKL and OPG.

Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA.

J Bone Miner Res. 2004 Feb;19(2):235-44. Epub 2003 Dec 16.PMID: 14969393 [PubMed - indexed for MEDLINE]Related articles

Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.

Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM.

J Invest Dermatol. 2003 Oct;121(4):688-94.PMID: 14632183 [PubMed - indexed for MEDLINE]Related articlesFree article

bFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells.

Nauman EA, Sakata T, Keaveny TM, Halloran BP, Bikle DD.

Calcif Tissue Int. 2003 Aug;73(2):147-52.PMID: 14565596 [PubMed - indexed for MEDLINE]Related articles

The impact of skeletal unloading on bone formation.

Bikle DD, Sakata T, Halloran BP.

Gravit Space Biol Bull. 2003 Jun;16(2):45-54. Review.PMID: 12959131 [PubMed - indexed for MEDLINE]Related articles

Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why?

Bikle DD, Xie Z, Ng D, Tu CL, Oda Y.

Recent Results Cancer Res. 2003;164:111-22. Review.PMID: 12899516 [PubMed - indexed for MEDLINE]Related articles

Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation.

Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD.

Mol Endocrinol. 2003 Nov;17(11):2329-39. Epub 2003 Jul 31.PMID: 12893881 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal unloading induces resistance to insulin-like growth factor I on bone formation.

Sakata T, Halloran BP, Elalieh HZ, Munson SJ, Rudner L, Venton L, Ginzinger D, Rosen CJ, Bikle DD.

Bone. 2003 Jun;32(6):669-80.PMID: 12810174 [PubMed - indexed for MEDLINE]Related articles

Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma.

Yang LC, Ng DC, Bikle DD.

J Cell Physiol. 2003 May;195(2):249-59.PMID: 12652652 [PubMed - indexed for MEDLINE]Related articles

Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.

Dolezalova H, Shankar G, Huang MC, Bikle DD, Goetzl EJ.

J Cell Biochem. 2003 Mar 1;88(4):732-43.PMID: 12577307 [PubMed - indexed for MEDLINE]Related articles

Mechanical and chemical characteristics of mineral produced by basic fibroblast growth factor-treated bone marrow stromal cells in vitro.

Nauman EA, Ebenstein DM, Hughes KF, Pruitt L, Halloran BP, Bikle DD, Keaveny TM.

Tissue Eng. 2002 Dec;8(6):931-9.PMID: 12542939 [PubMed - indexed for MEDLINE]Related articles

Vitamin D regulated keratinocyte differentiation: role of coactivators.

Bikle DD, Tu CL, Xie Z, Oda Y.

J Cell Biochem. 2003 Feb 1;88(2):290-5. Review.PMID: 12520529 [PubMed - indexed for MEDLINE]Related articles

The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3.

Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z.

J Invest Dermatol. 2002 Nov;119(5):1109-13.PMID: 12445200 [PubMed - indexed for MEDLINE]Related articlesFree article