PubMed

Morphology of pancreatic islets: a time course of pre-diabetes in Zucker fatty rats.

Augstein P, Salzsieder E.

Methods Mol Biol. 2009;560:159-89.PMID: 19504250 [PubMed - in process]Related articles

Glycemic variability correlates strongly with postprandial beta-cell dysfunction in a segment of type 2 diabetic patients using oral hypoglycemic agents.

Kohnert KD, Augstein P, Zander E, Heinke P, Peterson K, Freyse EJ, Hovorka R, Salzsieder E.

Diabetes Care. 2009 Jun;32(6):1058-62. Epub 2009 Feb 24.PMID: 19244086 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships between glucose variability and conventional measures of glycemic control in continuously monitored patients with type 2 diabetes.

Kohnert KD, Vogt L, Augstein P, Heinke P, Zander E, Peterson K, Freyse EJ, Salzsieder E.

Horm Metab Res. 2009 Feb;41(2):137-41. Epub 2009 Feb 12.PMID: 19214924 [PubMed - indexed for MEDLINE]Related articles

Impact of cytokine- and FasL-induced apoptosis in the beta-cell line NIT-1.

Augstein P, Heinke P, Schober C, Salzsieder E.

Horm Metab Res. 2009 Mar;41(3):207-12. Epub 2008 Oct 29.PMID: 18975252 [PubMed - indexed for MEDLINE]Related articles

Dominance of cytokine- over FasL-induced impairment of the mitochondrial transmembrane potential (Deltapsim) in the pancreatic beta-cell line NIT-1.

Augstein P, Heinke P, Salzsieder E, Grimm R, Giebel J, Salzsieder C, Harrison LC.

Diab Vasc Dis Res. 2008 Sep;5(3):198-204.PMID: 18777493 [PubMed - indexed for MEDLINE]Related articles

Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance.

Augstein P, Berg S, Heinke P, Altmann S, Salzsieder E, Demuth HU, Freyse EJ.

Diabetes Obes Metab. 2008 Sep;10(10):850-61. Epub 2007 Oct 29.PMID: 17970756 [PubMed - indexed for MEDLINE]Related articles

Telemedicine-Based KADIS(R) Combined with CGMS Has High Potential for Improving Outpatient Diabetes Care.

Salzsieder E, Augstein P, Vogt L, Kohnert KD, Heinke P, Freyse EJ, Azim Ahmed A, Metwali Z, Salman I, Attef O.

J Diabetes Sci Technol. 2007 Jul;1(4):511-21.PMID: 19885114 [PubMed - in process]Free article

Outpatient assessment of Karlsburg Diabetes Management System-based decision support.

Augstein P, Vogt L, Kohnert KD, Freyse EJ, Heinke P, Salzsieder E.

Diabetes Care. 2007 Jul;30(7):1704-8. Epub 2007 Apr 27.PMID: 17468357 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic hyperglycemia but not glucose variability determines HbA1c levels in well-controlled patients with type 2 diabetes.

Kohnert KD, Augstein P, Heinke P, Zander E, Peterson K, Freyse EJ, Salzsieder E.

Diabetes Res Clin Pract. 2007 Sep;77(3):420-6. Epub 2007 Feb 28.PMID: 17331614 [PubMed - indexed for MEDLINE]Related articles

Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.

Wargent E, Stocker C, Augstein P, Heinke P, Meyer A, Hoffmann T, Subramanian A, Sennitt MV, Demuth HU, Arch JR, Cawthorne MA.

Diabetes Obes Metab. 2005 Mar;7(2):170-81.PMID: 15715890 [PubMed - indexed for MEDLINE]Related articles

Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.

Augstein P, Bahr J, Wachlin G, Heinke P, Berg S, Salzsieder E, Harrison LC.

J Autoimmun. 2004 Dec;23(4):301-9.PMID: 15571924 [PubMed - indexed for MEDLINE]Related articles

Fas ligand down-regulates cytokine-induced Fas receptor expression on insulinoma (NIT-1), but not islet cells, from autoimmune nonobese diabetic mice.

Augstein P, Heinke P, Salzsieder E, Berg S, Rettig R, Salzsieder C, Harrison LC.

Endocrinology. 2004 Jun;145(6):2747-52. Epub 2004 Mar 19.PMID: 15033908 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction.

Wachlin G, Augstein P, Schröder D, Kuttler B, Klöting I, Heinke P, Schmidt S.

J Autoimmun. 2003 Jun;20(4):303-12.PMID: 12791316 [PubMed - indexed for MEDLINE]Related articles

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide.

Martinez NR, Augstein P, Moustakas AK, Papadopoulos GK, Gregori S, Adorini L, Jackson DC, Harrison LC.

J Clin Invest. 2003 May;111(9):1365-71.PMID: 12727928 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-gamma expression in splenic T cells.

Augstein P, Dunger A, Heinke P, Wachlin G, Berg S, Hehmke B, Salzsieder E.

Biochem Biophys Res Commun. 2003 May 2;304(2):378-84.PMID: 12711326 [PubMed - indexed for MEDLINE]Related articles

Surface and intracellular Fas expression associated with cytokine-induced apoptosis in rodent islet and insulinoma cells.

Augstein P, Wachlin G, Berg S, Bahr J, Salzsieder C, Hehmke B, Heinke P, Salzsieder E.

J Mol Endocrinol. 2003 Apr;30(2):163-71.PMID: 12683940 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell surface trafficking of Fas in NIT-1 cells and dissection of surface and total Fas expression.

Augstein P, Dunger A, Salzsieder C, Heinke P, Kubernath R, Bahr J, Fischer U, Rettig R, Salzsieder E.

Biochem Biophys Res Commun. 2002 Jan 11;290(1):443-51.PMID: 11779190 [PubMed - indexed for MEDLINE]Related articles

Sequence variations in the NDUFA1 gene encoding a subunit of complex I of the respiratory chain.

Wittig I, Augstein P, Brown GK, Fujii T, Rötig A, Rustin P, Munnich A, Seibel P, Thorburn D, Wissinger B, Tamboom K, Metspalu A, Lamantea E, Zeviani M, Wehnert MS.

J Inherit Metab Dis. 2001 Feb;24(1):15-27.PMID: 11286378 [PubMed - indexed for MEDLINE]Related articles

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes.

Augstein P, Elefanty AG, Allison J, Harrison LC.

Diabetologia. 1998 Nov;41(11):1381-8.PMID: 9833948 [PubMed - indexed for MEDLINE]Related articles

Beta-cell apoptosis in an accelerated model of autoimmune diabetes.

Augstein P, Stephens LA, Allison J, Elefanty AG, Ekberg M, Kay TW, Harrison LC.

Mol Med. 1998 Aug;4(8):495-501.PMID: 9742505 [PubMed - indexed for MEDLINE]Related articlesFree article

Sensitive monoclonal antibody-based sandwich ELISA for determination of the diabetes-associated autoantigen glutamic acid decarboxylase GAD65.

Schlosser M, Hahmann J, Ziegler B, Augstein P, Ziegler M.

J Immunoassay. 1997 Nov;18(4):289-307.PMID: 9358337 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical differentiation of monoclonal GAD antibodies recognizing linear or conformational epitope regions.

Augstein P, Ziegler B, Schlosser M, Flassig S, Strebelow M, Ziegler M.

Pancreas. 1997 Aug;15(2):139-46.PMID: 9260198 [PubMed - indexed for MEDLINE]Related articles

A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice.

Harrison LC, Honeyman MC, Trembleau S, Gregori S, Gallazzi F, Augstein P, Brusic V, Hammer J, Adorini L.

J Exp Med. 1997 Mar 17;185(6):1013-21.PMID: 9091575 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine monoclonal glutamic acid decarboxylase (GAD)65 antibodies recognize autoimmune-associated GAD epitope regions targeted in patients with type 1 diabetes mellitus and stiff-man syndrome.

Ziegler B, Schlosser M, Lühder F, Strebelow M, Augstein P, Northemann W, Powers AC, Ziegler M.

Acta Diabetol. 1996 Sep;33(3):225-31.PMID: 8904930 [PubMed - indexed for MEDLINE]Related articles

Identification of interleukin 1-induced apoptosis in rat islets using in situ specific labelling of fragmented DNA.

Dunger A, Augstein P, Schmidt S, Fischer U.

J Autoimmun. 1996 Jun;9(3):309-13.PMID: 8816965 [PubMed - indexed for MEDLINE]Related articles

Comparison of the islet cell antibody pattern of monoclonal glutamic acid decarboxylase antibodies recognizing linear and conformational epitopes.

Augstein P, Schlosser M, Ziegler B, Hahmann J, Mauch L, Ziegler M.

Acta Histochem. 1996 Apr;98(2):229-41.PMID: 8739307 [PubMed - indexed for MEDLINE]Related articles

Glutamate decarboxylase (GAD) is not detectable on the surface of rat islet cells examined by cytofluorometry and complement-dependent antibody-mediated cytotoxicity of monoclonal GAD antibodies.

Ziegler B, Augstein P, Schröder D, Mauch L, Hahmann J, Schlosser M, Ziegler M.

Horm Metab Res. 1996 Jan;28(1):11-5.PMID: 8820987 [PubMed - indexed for MEDLINE]Related articles

Impact of metabolic activity of beta cells on cytokine-induced damage and recovery of rat pancreatic islets.

Dunger A, Schröder D, Augstein P, Witstruck T, Wachlin G, Vogt L, Ziegler B, Schmidt S.

Acta Diabetol. 1995 Dec;32(4):217-24.PMID: 8750759 [PubMed - indexed for MEDLINE]Related articles

Occurrence of islet cell reactive autoantibodies in diabetes-prone BB/OK rats is not associated with the onset of diabetes: a cross-sectional study of BB rats and their diabetes-resistant congenic strains.

Schlosser M, Ziegler B, Augstein P, Klöting I, Ziegler M.

Diabetes Res. 1994;26(2):67-77.PMID: 7554727 [PubMed - indexed for MEDLINE]Related articles

Monoclonal antibodies specific to the glutamic acid decarboxylase 65 kDa isoform derived from a non-obese diabetic (NOD) mouse.

Ziegler B, Augstein P, Lühder F, Northemann W, Hamann J, Schlosser M, Klöting I, Michaelis D, Ziegler M.

Diabetes Res. 1994;25(2):47-64.PMID: 7544254 [PubMed - indexed for MEDLINE]Related articles

Induction of islet cell surface and insulin antibodies in Balb/c mice by application of porcine insulin and Freund's adjuvant is not associated with insulitis.

Augstein P, Kohnert KD, Ziegler B, Fürll B, Heinke P, Ziegler M.

Horm Metab Res. 1993 Jul;25(7):344-7.PMID: 8406317 [PubMed - indexed for MEDLINE]Related articles

Characterization of monoclonal islet cell reactive autoantibodies from the diabetic biobreeding (BB/OK) rat.

Ziegler B, Witt S, Kohnert KD, Schlosser M, Augstein P, Michaelis D, Klöting I, Ziegler M.

Acta Diabetol. 1993;30(4):201-6.PMID: 8180412 [PubMed - indexed for MEDLINE]Related articles

Characterization of two porcine proinsulin reactive monoclonal antibodies by immunostaining of beta-cells in pancreatic sections of different species.

Augstein P, Braun B, Ziegler B, Woltanski KP, Ziegler M.

Acta Histochem. 1992;93(2):433-40.PMID: 1283801 [PubMed - indexed for MEDLINE]Related articles