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Bivariate heritability of total and regional brain volumes: the Framingham Study.

DeStefano AL, Seshadri S, Beiser A, Atwood LD, Massaro JM, Au R, Wolf PA, DeCarli C.

Alzheimer Dis Assoc Disord. 2009 Jul-Sep;23(3):218-23.PMID: 19812462 [PubMed - in process]Related articles

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.

Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O'Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O'Connell JR, Borecki IB, van Duijn CM, Cupples LA, Fox CS, North KE.

PLoS Genet. 2009 Jun;5(6):e1000539. Epub 2009 Jun 26.PMID: 19557197 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of the Framingham Heart Study population.

Govindaraju DR, Cupples LA, Kannel WB, O'Donnell CJ, Atwood LD, D'Agostino RB Sr, Fox CS, Larson M, Levy D, Murabito J, Vasan RS, Splansky GL, Wolf PA, Benjamin EJ.

Adv Genet. 2008;62:33-65. Review.PMID: 19010253 [PubMed - indexed for MEDLINE]Related articles

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.

Larson MG, Atwood LD, Benjamin EJ, Cupples LA, D'Agostino RB Sr, Fox CS, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Murabito JM, Newton-Cheh C, O'Donnell CJ, Seshadri S, Vasan RS, Wang TJ, Wolf PA, Levy D.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S5.PMID: 17903304 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project.

Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S18.PMID: 17903300 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.

Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D'Agostino RB Sr, Decarli C, Atwood LD, Wolf PA.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S15.PMID: 17903297 [PubMed - indexed for MEDLINE]Related articlesFree article

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.

Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB Sr, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD.

BMC Med Genet. 2007;8 Suppl 1:S1.PMID: 17903291 [PubMed - indexed for MEDLINE]Related articlesFree article

A chromosome 11q quantitative-trait locus influences change of blood-pressure measurements over time in Mexican Americans of the San Antonio Family Heart Study.

Rutherford S, Cai G, Lopez-Alvarenga JC, Kent JW, Voruganti VS, Proffitt JM, Curran JE, Johnson MP, Dyer TD, Jowett JB, Bastarrachea RA, Atwood LD, Goring HH, Maccluer JW, Moses EK, Blangero J, Comuzzie AG, Cole SA.

Am J Hum Genet. 2007 Oct;81(4):744-55. Epub 2007 Aug 20.PMID: 17846999 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability, linkage, and genetic associations of exercise treadmill test responses.

Ingelsson E, Larson MG, Vasan RS, O'Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S.

Circulation. 2007 Jun 12;115(23):2917-24. Epub 2007 Jun 4.PMID: 17548724 [PubMed - indexed for MEDLINE]Related articlesFree article

A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study.

Sherva R, Miller MB, Lynch AI, Devereux RB, Rao DC, Oberman A, Hopkins PN, Kitzman DW, Atwood LD, Arnett DK.

Am J Hypertens. 2007 Apr;20(4):398-402.PMID: 17386346 [PubMed - indexed for MEDLINE]Related articlesFree article

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination.

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D'Agostino RB Sr, Fox CS, Larson MG, Murabito JM, O'Donnell CJ, Vasan RS, Wolf PA, Levy D.

Am J Epidemiol. 2007 Jun 1;165(11):1328-35. Epub 2007 Mar 19.PMID: 17372189 [PubMed - indexed for MEDLINE]Related articlesFree article

Allele frequency misspecification: effect on power and Type I error of model-dependent linkage analysis of quantitative traits under random ascertainment.

Mandal DM, Sorant AJ, Atwood LD, Wilson AF, Bailey-Wilson JE.

BMC Genet. 2006 Apr 20;7:21.PMID: 16618369 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study.

Atwood LD, Heard-Costa NL, Fox CS, Jaquish CE, Cupples LA.

BMC Genet. 2006 Jan 26;7:7.PMID: 16438729 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for white matter hyperintensity: the Framingham Heart Study.

DeStefano AL, Atwood LD, Massaro JM, Heard-Costa N, Beiser A, Au R, Wolf PA, DeCarli C.

Stroke. 2006 Jan;37(1):77-81. Epub 2005 Dec 1.PMID: 16322484 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex-specific association between estrogen receptor-alpha gene variation and measures of adiposity: the Framingham Heart Study.

Fox CS, Yang Q, Cupples LA, Guo CY, Atwood LD, Murabito JM, Levy D, Mendelsohn ME, Housman DE, Shearman AM.

J Clin Endocrinol Metab. 2005 Nov;90(11):6257-62. Epub 2005 Sep 6.PMID: 16144952 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome scan for linkage with aortic root diameter in hypertensive African Americans and whites in the Hypertension Genetic Epidemiology Network (HyperGEN) study.

Lynch AI, Arnett DK, Atwood LD, Devereux RB, Kitzman DW, Hopkins PN, Oberman A, Rao DC.

Am J Hypertens. 2005 May;18(5 Pt 1):627-32.PMID: 15882545 [PubMed - indexed for MEDLINE]Related articles

Genomewide linkage analysis of weight change in the Framingham Heart Study.

Fox CS, Heard-Costa NL, Vasan RS, Murabito JM, D'Agostino RB Sr, Atwood LD; Framingham Heart Study.

J Clin Endocrinol Metab. 2005 Jun;90(6):3197-201. Epub 2005 Mar 15.PMID: 15769990 [PubMed - indexed for MEDLINE]Related articlesFree article

X-linked high myopia associated with cone dysfunction.

Young TL, Deeb SS, Ronan SM, Dewan AT, Alvear AB, Scavello GS, Paluru PC, Brott MS, Hayashi T, Holleschau AM, Benegas N, Schwartz M, Atwood LD, Oetting WS, Rosenberg T, Motulsky AG, King RA.

Arch Ophthalmol. 2004 Jun;122(6):897-908.PMID: 15197065 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation in white matter hyperintensity volume in the Framingham Study.

Atwood LD, Wolf PA, Heard-Costa NL, Massaro JM, Beiser A, D'Agostino RB, DeCarli C.

Stroke. 2004 Jul;35(7):1609-13. Epub 2004 May 13.PMID: 15143299 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide linkage to chromosome 6 for waist circumference in the Framingham Heart Study.

Fox CS, Heard-Costa NL, Wilson PW, Levy D, D'Agostino RB Sr, Atwood LD.

Diabetes. 2004 May;53(5):1399-402.PMID: 15111512 [PubMed - indexed for MEDLINE]Related articlesFree article

Consistency of linkage results across exams and methods in the Framingham Heart Study.

Atwood LD, Heard-Costa NL, Cupples LA, Levy D; Framingham Heart Study.

BMC Genet. 2003 Dec 31;4 Suppl 1:S30.PMID: 14975098 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach.

Yang Q, Chazaro I, Cui J, Guo CY, Demissie S, Larson M, Atwood LD, Cupples LA, DeStefano AL.

BMC Genet. 2003 Dec 31;4 Suppl 1:S29.PMID: 14975097 [PubMed - indexed for MEDLINE]Related articlesFree article

Two quantitative trait loci affect ACE activities in Mexican-Americans.

Kammerer CM, Gouin N, Samollow PB, VandeBerg JF, Hixson JE, Cole SA, MacCluer JW, Atwood LD.

Hypertension. 2004 Feb;43(2):466-70. Epub 2004 Jan 5.PMID: 14707162 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study.

Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K, Atwood LD, Heard-Costa NL, Herbert A, O'Connor GT, Gottlieb DJ.

Hum Mol Genet. 2003 Nov 1;12(21):2745-51. Epub 2003 Sep 9.PMID: 12966033 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

Li JL, Hayden MR, Almqvist EW, Brinkman RR, Durr A, Dodé C, Morrison PJ, Suchowersky O, Ross CA, Margolis RL, Rosenblatt A, Gómez-Tortosa E, Cabrero DM, Novelletto A, Frontali M, Nance M, Trent RJ, McCusker E, Jones R, Paulsen JS, Harrison M, Zanko A, Abramson RK, Russ AL, Knowlton B, Djoussé L, Mysore JS, Tariot S, Gusella MF, Wheeler VC, Atwood LD, Cupples LA, Saint-Hilaire M, Cha JH, Hersch SM, Koroshetz WJ, Gusella JF, MacDonald ME, Myers RH.

Am J Hum Genet. 2003 Sep;73(3):682-7. Epub 2003 Aug 1.PMID: 12900792 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

Karamohamed S, Demissie S, Volcjak J, Liu C, Heard-Costa N, Liu J, Shoemaker CM, Panhuysen CI, Meigs JB, Wilson P, Atwood LD, Cupples LA, Herbert A; NHLBI Framingham Heart Study.

Diabetes. 2003 Jun;52(6):1562-7.PMID: 12765971 [PubMed - indexed for MEDLINE]Related articlesFree article

Limits of fine-mapping a quantitative trait.

Atwood LD, Heard-Costa NL.

Genet Epidemiol. 2003 Feb;24(2):99-106.PMID: 12548671 [PubMed - indexed for MEDLINE]Related articles

Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study.

Atwood LD, Heard-Costa NL, Cupples LA, Jaquish CE, Wilson PW, D'Agostino RB.

Am J Hum Genet. 2002 Nov;71(5):1044-50. Epub 2002 Sep 27.PMID: 12355400 [PubMed - indexed for MEDLINE]Related articlesFree article

Sibling resemblance for left ventricular structure, contractility, and diastolic filling.

Tang W, Arnett DK, Devereux RB, Province MA, Atwood LD, Oberman A, Hopkins PN, Kitzman DW.

Hypertension. 2002 Sep;40(3):233-8.PMID: 12215459 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage of left ventricular early diastolic peak filling velocity to chromosome 5 in hypertensive African Americans: the HyperGEN echocardiography study.

Tang W, Arnett DK, Devereux RB, Atwood LD, Kitzman DW, Rao DC.

Am J Hypertens. 2002 Jul;15(7 Pt 1):621-7.PMID: 12118910 [PubMed - indexed for MEDLINE]Related articles

Genome scans for blood pressure and hypertension: the National Heart, Lung, and Blood Institute Family Heart Study.

Hunt SC, Ellison RC, Atwood LD, Pankow JS, Province MA, Leppert MF.

Hypertension. 2002 Jul;40(1):1-6.PMID: 12105129 [PubMed - indexed for MEDLINE]Related articlesFree article

Refined mapping of suggestive linkage to renal function in African Americans: the HyperGEN study.

DeWan AT, Arnett DK, Miller MB, Peacock JM, Atwood LD, Province MA, Lewis CE, Hunt SC, Eckfeldt JH.

Am J Hum Genet. 2002 Jul;71(1):204-5. No abstract available. PMID: 12068377 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study.

Peacock JM, Arnett DK, Atwood LD, Myers RH, Coon H, Rich SS, Province MA, Heiss G.

Arterioscler Thromb Vasc Biol. 2001 Nov;21(11):1823-8.PMID: 11701472 [PubMed - indexed for MEDLINE]Related articlesFree article

Further refinement of the MYP2 locus for autosomal dominant high myopia by linkage disequilibrium analysis.

Young TL, Atwood LD, Ronan SM, Dewan AT, Alvear AB, Peterson J, Holleschau A, King RA.

Ophthalmic Genet. 2001 Jun;22(2):69-75.PMID: 11449316 [PubMed - indexed for MEDLINE]Related articles

Evidence for a major gene influence on abdominal fat distribution: the Minnesota Breast Cancer Family Study.

Olson JE, Atwood LD, Grabrick DM, Vachon CM, Sellers TA.

Genet Epidemiol. 2001 May;20(4):458-78.PMID: 11319785 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage analysis of blood pressure in Mexican Americans.

Atwood LD, Samollow PB, Hixson JE, Stern MP, MacCluer JW.

Genet Epidemiol. 2001 Apr;20(3):373-82.PMID: 11255245 [PubMed - indexed for MEDLINE]Related articles

Genome-wide linkage analysis of pulse pressure in Mexican Americans.

Atwood LD, Samollow PB, Hixson JE, Stern MP, MacCluer JW.

Hypertension. 2001 Feb;37(2 Part 2):425-8.PMID: 11230312 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome scan for renal function among hypertensives: the HyperGEN study.

DeWan AT, Arnett DK, Atwood LD, Province MA, Lewis CE, Hunt SC, Eckfeldt J.

Am J Hum Genet. 2001 Jan;68(1):136-144. Epub 2000 Dec 12.PMID: 11115379 [PubMed - indexed for MEDLINE]Related articlesFree article

Possible locus on chromosome 18q influencing postural systolic blood pressure changes.

Pankow JS, Rose KM, Oberman A, Hunt SC, Atwood LD, Djoussé L, Province MA, Rao DC.

Hypertension. 2000 Oct;36(4):471-6.PMID: 11040221 [PubMed - indexed for MEDLINE]Related articlesFree article

Segregation analysis of serum uric acid in the NHLBI Family Heart Study.

Wilk JB, Djousse L, Borecki I, Atwood LD, Hunt SC, Rich SS, Eckfeldt JH, Arnett DK, Rao DC, Myers RH.

Hum Genet. 2000 Mar;106(3):355-9.PMID: 10798367 [PubMed - indexed for MEDLINE]Related articles

Preliminary sibpair linkage analysis of percent mammographic density.

Vachon CM, King RA, Atwood LD, Kuni CC, Sellers TA.

J Natl Cancer Inst. 1999 Oct 20;91(20):1778-9. No abstract available. PMID: 10528030 [PubMed - indexed for MEDLINE]Related articlesFree article

No linkage of the lipoprotein lipase locus to hypertension in Caucasians.

Hunt SC, Province MA, Atwood LD, Sholinsky P, Lalouel JM, Rao DC, Williams RR, Leppert MF.

J Hypertens. 1999 Jan;17(1):39-43.PMID: 10100092 [PubMed - indexed for MEDLINE]Related articles

A second locus for familial high myopia maps to chromosome 12q.

Young TL, Ronan SM, Alvear AB, Wildenberg SC, Oetting WS, Atwood LD, Wilkin DJ, King RA.

Am J Hum Genet. 1998 Nov;63(5):1419-24.PMID: 9792869 [PubMed - indexed for MEDLINE]Related articlesFree article

Two major loci control variation in beta-lipoprotein cholesterol and response to dietary fat and cholesterol in baboons.

Rainwater DL, Kammerer CM, Hixson JE, Carey KD, Rice KS, Dyke B, VandeBerg JF, Slifer SH, Atwood LD, McGill HC Jr, Vandeberg JL.

Arterioscler Thromb Vasc Biol. 1998 Jul;18(7):1061-8.PMID: 9672066 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that a locus for familial high myopia maps to chromosome 18p.

Young TL, Ronan SM, Drahozal LA, Wildenberg SC, Alvear AB, Oetting WS, Atwood LD, Wilkin DJ, King RA.

Am J Hum Genet. 1998 Jul;63(1):109-19.PMID: 9634508 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage of essential hypertension to the angiotensinogen locus in Mexican Americans.

Atwood LD, Kammerer CM, Samollow PB, Hixson JE, Shade RE, MacCluer JW.

Hypertension. 1997 Sep;30(3 Pt 1):326-30.PMID: 9314412 [PubMed - indexed for MEDLINE]Related articlesFree article

Prior segregation analysis and the power to detect linkage.

Atwood LD, Slifer SH.

Genet Epidemiol. 1997;14(6):755-60.PMID: 9433573 [PubMed - indexed for MEDLINE]Related articles

Impact of adjustments for intermediate phenotypes on the power to detect linkage.

Arnett DK, Pankow JS, Atwood LD, Sellers TA.

Genet Epidemiol. 1997;14(6):749-54.PMID: 9433572 [PubMed - indexed for MEDLINE]Related articles

Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures.

Mitchell BD, Kammerer CM, Mahaney MC, Blangero J, Comuzzie AG, Atwood LD, Haffner SM, Stern MP, MacCluer JW.

Arterioscler Thromb Vasc Biol. 1996 Feb;16(2):281-8.PMID: 8620344 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a major gene affecting postchallenge insulin levels in Mexican-Americans.

Mitchell BD, Kammerer CM, Hixson JE, Atwood LD, Hackleman S, Blangero J, Haffner SM, Stern MP, MacCluer JW.

Diabetes. 1995 Mar;44(3):284-9.PMID: 7883115 [PubMed - indexed for MEDLINE]Related articles