PubMed

Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia.

Real JT, Martínez-Hervás S, Tormos MC, Domenech E, Pallardó FV, Sáez-Tormo G, Redon J, Carmena R, Chaves FJ, Ascaso JF, García-García AB.

Metabolism. 2009 Sep 30. [Epub ahead of print]PMID: 19800085 [PubMed - as supplied by publisher]Related articles

Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention.

Millán J, Pintó X, Muñoz A, Zúñiga M, Rubiés-Prat J, Pallardo LF, Massana L, Mangas A, Mijares AH, González-Santos P, Ascaso JF, Pedro-Botet J.

Vasc Health Risk Manag. 2009;5:757-65. Epub 2009 Sep 18.PMID: 19774217 [PubMed - in process]Related articlesFree article

Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.

Martinez-Hervas S, Real JT, Ivorra C, Priego A, Chaves FJ, Pallardo FV, Viña JR, Redon J, Carmena R, Ascaso JF.

Nutr Metab Cardiovasc Dis. 2009 Sep 16. [Epub ahead of print]PMID: 19765958 [PubMed - as supplied by publisher]Related articles

FABP4 plasma levels are increased in familial combined hyperlipidemia.

Cabre A, Lazaro I, Cofan M, Jarauta E, Plana N, Garcia-Otin AL, Ascaso JF, Ferre R, Civeira F, Ros E, Masana L.

J Lipid Res. 2009 Apr 24. [Epub ahead of print]PMID: 19395698 [PubMed - as supplied by publisher]Related articlesFree article

[Abdominal obesity, insulin resistance and metabolic and vascular risk]

Ascaso JF.

Med Clin (Barc). 2008 Sep 27;131(10):380-1. Spanish. No abstract available. PMID: 18842212 [PubMed - indexed for MEDLINE]Related articles

[Cardiovascular risk in subjects with high probability of metabolic syndrome and insulin resistance. DESIRE study]

Goday A, Gabriel R, Ascaso JF, Franch J, Ortega R, Martínez O, Lerones N; DESIRE study.

Rev Clin Esp. 2008 Sep;208(8):377-85. Spanish. PMID: 18817695 [PubMed - indexed for MEDLINE]Related articles

[8-oxo-7,8-dihydro-2'-deoxyguanosine as a marker of DNA oxidative stress in individuals with combined familiar hyperlipidemia]

Ferri J, Martínez-Hervás S, Espinosa O, Fandos M, Pedro T, Real JT, Chaves FJ, Cerdá C, Sáez G, Ascaso JF.

Med Clin (Barc). 2008 Jun 7;131(1):1-4. Spanish. PMID: 18582415 [PubMed - indexed for MEDLINE]Related articles

A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia.

Blesa S, Vernia S, Garcia-Garcia AB, Martinez-Hervas S, Ivorra C, Gonzalez-Albert V, Ascaso JF, Martín-Escudero JC, Real JT, Carmena R, Casado M, Chaves FJ.

J Clin Endocrinol Metab. 2008 Sep;93(9):3577-83. Epub 2008 Jun 17. Erratum in: J Clin Endocrinol Metab. 2009 Jan;94(1):325. PMID: 18559913 [PubMed - indexed for MEDLINE]Related articlesFree article

Classical cardiovascular risk factors according to fasting plasma glucose levels.

Martinez-Hervas S, Romero P, Hevilla EB, Real JT, Priego A, Martin-Moreno JM, Carmena R, Ascaso JF.

Eur J Intern Med. 2008 May;19(3):209-13. Epub 2007 Nov 8.PMID: 18395166 [PubMed - indexed for MEDLINE]Related articles

Evaluation of clinical diagnosis criteria of familial ligand defective apoB 100 and lipoprotein phenotype comparison between LDL receptor gene mutations affecting ligand-binding domain and the R3500Q mutation of the apoB gene in patients from a South European population.

Ejarque I, Real JT, Martinez-Hervas S, Chaves FJ, Blesa S, Garcia-Garcia AB, Millan E, Ascaso JF, Carmena R.

Transl Res. 2008 Mar;151(3):162-7. Epub 2008 Jan 7.PMID: 18279815 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and oxidative stress in familial combined hyperlipidemia.

Martinez-Hervas S, Fandos M, Real JT, Espinosa O, Chaves FJ, Saez GT, Salvador A, Cerdá C, Carmena R, Ascaso JF.

Atherosclerosis. 2008 Aug;199(2):384-9. Epub 2007 Dec 31.PMID: 18164710 [PubMed - indexed for MEDLINE]Related articles

Absence of cardiovascular autonomic dysfunction and vagal pancreatic impairment in idiopathic achalasia of the oesophagus.

Herreros B, Ascaso JF, Mora F, Costa AJ, Sanchiz V, Minguez M, Benages A.

Neurogastroenterol Motil. 2007 Aug;19(8):646-52.PMID: 17640179 [PubMed - indexed for MEDLINE]Related articles

[Diagnosis of metabolic syndrome. Adaptation of diagnostic criteria in our setting. Recommendations of the HDL forum]

Ascaso JF, González-Santos P, Hernández Mijares A, Mangas Rojas A, Masana Marín L, Millán Núñez-Cortés J, Pallardo LF, Pedro-Botet J, Pérez-Jiménez F, Pintó X, Plaza I, Rubiés-Prat J, Zúñiga M; FORO-HDL.

Rev Clin Esp. 2006 Dec;206(11):576-82. Spanish. No abstract available. PMID: 17178079 [PubMed - indexed for MEDLINE]Related articles

[Familial combined hyperlipidemia, metabolic syndrome and cardiovascular disease]

Martinez-Hervás S, Real JT, Priego A, Sanz J, Martín JM, Carmena R, Ascaso JF.

Rev Esp Cardiol. 2006 Nov;59(11):1195-8. Spanish. PMID: 17144994 [PubMed - indexed for MEDLINE]Related articlesFree article

[Role of atherogenic dyslipidemia in the development of metabolic syndrome]

Real JT, Romero P, Martínez Hervas S, Pedro T, Carmena R, Ascaso JF.

Med Clin (Barc). 2006 Sep 9;127(9):321-4. Spanish. PMID: 16987450 [PubMed - indexed for MEDLINE]Related articles

Oesophageal motility disorders in type 1 diabetes mellitus and their relation to cardiovascular autonomic neuropathy.

Ascaso JF, Herreros B, Sanchiz V, Lluch I, Real JT, Minguez M, Mora F, Benages A.

Neurogastroenterol Motil. 2006 Sep;18(9):813-22.PMID: 16918760 [PubMed - indexed for MEDLINE]Related articles

Semiquantitative multiplex PCR: a useful tool for large rearrangement screening and characterization.

Garcia-Garcia AB, Blesa S, Martinez-Hervas S, Mansego ML, Gonzalez-Albert V, Ascaso JF, Carmena R, Real JT, Chaves FJ.

Hum Mutat. 2006 Aug;27(8):822-8.PMID: 16791839 [PubMed - indexed for MEDLINE]Related articles

[Effect of gender and obesity on postprandial lipemia in non-diabetic normolipidemic subjects and subjects with familial combined hyperlipidemia]

Bartual A, González C, Martínez Hervás S, Real JT, García García AB, Castro Cabezas M, Chaves FJ, Priego MA, Ascaso JF, Carmena R.

Rev Clin Esp. 2006 May;206(5):213-9. Spanish. PMID: 16750103 [PubMed - indexed for MEDLINE]Related articles

Analysis of sequence variations in the LDL receptor gene in Spain: general gene screening or search for specific alterations?

Blesa S, Garcia-Garcia AB, Martinez-Hervas S, Mansego ML, Gonzalez-Albert V, Ascaso JF, Carmena R, Real JT, Chaves FJ.

Clin Chem. 2006 Jun;52(6):1021-5. Epub 2006 Apr 20.PMID: 16627557 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of a controlled program of moderate physical exercise on insulin sensitivity in nonobese, nondiabetic subjects.

Hasbum B, Real JT, Sánchez C, Priego MA, Díaz J, Viguer A, Basanta M, Martínez-Valls J, Marín J, Carmena R, Ascaso JF.

Clin J Sport Med. 2006 Jan;16(1):46-50.PMID: 16377975 [PubMed - indexed for MEDLINE]Related articles

[Determinants of postprandial lipemia measured as diurnal triglyceride profile in non diabetic normolipidemic subjects]

González C, Real JT, Bartual A, Chaves FJ, García-García AB, Blesa S, Castro-Cabezas M, Ascaso JF, Carmena R.

Med Clin (Barc). 2005 Oct 8;125(12):448-52. Spanish. PMID: 16216199 [PubMed - indexed for MEDLINE]Related articles

Effects of marathon running on plasma total homocysteine concentrations.

Real JT, Merchante A, Gómez JL, Chaves FJ, Ascaso JF, Carmena R.

Nutr Metab Cardiovasc Dis. 2005 Apr;15(2):134-9. Epub 2005 Apr 13.PMID: 15871862 [PubMed - indexed for MEDLINE]Related articles

Influence of microsomal triglyceride transfer protein promoter polymorphism -493 GT on fasting plasma triglyceride values and interaction with treatment response to atorvastatin in subjects with heterozygous familial hypercholesterolaemia.

García-García AB, González C, Real JT, Martín de Llano JJ, González-Albert V, Civera M, Chaves FJ, Ascaso JF, Carmena R.

Pharmacogenet Genomics. 2005 Apr;15(4):211-8.PMID: 15864113 [PubMed - indexed for MEDLINE]Related articles

Daylong triglyceridaemia in healthy Mediterranean and northern European subjects.

van Oostrom AJ, Real JT, Carmena R, Ascaso JF, Castro Cabezas M.

Neth J Med. 2004 Sep;62(8):279-85.PMID: 15588068 [PubMed - indexed for MEDLINE]Related articlesFree article

[Clinical and biochemical characteristics of familial ligand-defective apo B-100 in a South European population]

Ejarque I, Real JT, Chaves FJ, Blesa S, González V, Milian E, Ascaso JF, Priego MA, Carmena R.

Med Clin (Barc). 2004 Oct 9;123(12):456-9. Spanish. PMID: 15498441 [PubMed - indexed for MEDLINE]Related articles

Significance of high density lipoprotein-cholesterol in cardiovascular risk prevention: recommendations of the HDL Forum.

Ascaso JF, Fernández-Cruz A, González Santos P, Hernández Mijares A, Mangas Rojas A, Millán J, Felipe Pallardo L, Pedro-Botet J, Pérez-Jiménez F, Pía G, Pintó X, Plaza I, Rubiés-Prat J; HDL Forum.

Am J Cardiovasc Drugs. 2004;4(5):299-314. Review.PMID: 15449972 [PubMed - indexed for MEDLINE]Related articles

[Plasma lipoprotein (a) values in familial defective ligand apo B 100 in a South European population]

Ejarque I, Leal JT, Ascaso JF, Chaves FJ, Milian E, Priego MA, Carmena R.

An Med Interna. 2004 Jul;21(7):322-5. Spanish. PMID: 15347236 [PubMed - indexed for MEDLINE]Related articles

Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism.

Ascaso JF, Pardo S, Real JT, Lorente RI, Priego A, Carmena R.

Diabetes Care. 2003 Dec;26(12):3320-5.PMID: 14633821 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of LDL receptor gene mutations and the R3500Q mutation of the apoB gene on lipoprotein phenotype of familial hypercholesterolemic patients from a South European population.

Real JT, Chaves FJ, Ejarque I, García-García AB, Valldecabres C, Ascaso JF, Armengod ME, Carmena R.

Eur J Hum Genet. 2003 Dec;11(12):959-65.PMID: 14508510 [PubMed - indexed for MEDLINE]Related articlesFree article

Additional information on ApoB R3500Q mutation in Spain.

Real JT, Chaves JF, Ascaso JF, Armengod ME, Carmena R.

Atherosclerosis. 2003 Jun;168(2):399-400. No abstract available. PMID: 12801626 [PubMed - indexed for MEDLINE]Related articles

Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population.

Ascaso JF, Romero P, Real JT, Lorente RI, Marti;nez-Valls J, Carmena R.

Eur J Intern Med. 2003 Mar;14(2):101-106.PMID: 12719027 [PubMed - as supplied by publisher]Related articles

[Hyperthyroidism in the aged]

Real JT, Ascaso JF.

Med Clin (Barc). 2002 Jun 1;118(20):784-7. Review. Spanish. No abstract available. PMID: 12049696 [PubMed - indexed for MEDLINE]Related articles

[Influence of plasma lipids, APOE genotype and type of LDL receptor gene mutations on myocardial infarction in subjects with familial hypercholesterolemia]

Real JT, Ascaso JF, Chaves FJ, González C, Puig O, Armengod ME, Carmena R.

Med Clin (Barc). 2002 May 18;118(18):681-5. Spanish. PMID: 12042130 [PubMed - indexed for MEDLINE]Related articles

Impact of obesity in primary hyperlipidemias.

Carmena R, Ascaso JF, Real JT.

Nutr Metab Cardiovasc Dis. 2001 Oct;11(5):354-9. Review.PMID: 11887432 [PubMed - indexed for MEDLINE]Related articles

[Risk factors associated to hospitalization in diabetic patients with foot ulcers]

Real JT, Valls M, Ascaso P, Basanta ML, Viguer A A, Ascaso JF, Carmena R.

Med Clin (Barc). 2001 Nov 24;117(17):641-4. Spanish. PMID: 11734168 [PubMed - indexed for MEDLINE]Related articles

The influence of apo E phenotypes on the plasma triglycerides response to hormonal replacement therapy during the menopause.

Tolosa M, Peiró S, Real JT, Cano A, Ascaso JF, Carmena R.

Maturitas. 2001 Nov 30;40(2):173-81.PMID: 11716996 [PubMed - indexed for MEDLINE]Related articles

[Insulin resistance quantification by fasting insulin plasma values and HOMA index in a non-diabetic population]

Ascaso JF, Romero P, Real JT, Priego A, Valdecabres C, Carmena R.

Med Clin (Barc). 2001 Nov 3;117(14):530-3. Spanish. PMID: 11707218 [PubMed - indexed for MEDLINE]Related articles

Molecular genetics of familial hypercholesterolemia in Spain: Ten novel LDLR mutations and population analysis.

García-García AB, Real JT, Puig O, Cebolla E, Marín-García P, Martínez Ferrandis JI, García-Sogo M, Civera M, Ascaso JF, Carmena R, Armengod ME, Chaves FJ.

Hum Mutat. 2001 Nov;18(5):458-9.PMID: 11668640 [PubMed - indexed for MEDLINE]Related articles

Genetic diagnosis of familial hypercholesterolemia in a South European outbreed population: influence of low-density lipoprotein (LDL) receptor gene mutations on treatment response to simvastatin in total, LDL, and high-density lipoprotein cholesterol.

Chaves FJ, Real JT, García-García AB, Civera M, Armengod ME, Ascaso JF, Carmena R.

J Clin Endocrinol Metab. 2001 Oct;86(10):4926-32.PMID: 11600564 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the TaqIB polymorphism in the cholesteryl ester transfer protein gene locus and plasma lipoprotein levels in familial hypercholesterolemia.

Carmena-Ramón R, Ascaso JF, Real JT, Nájera G, Ordovás JM, Carmena R.

Metabolism. 2001 Jun;50(6):651-6.PMID: 11398140 [PubMed - indexed for MEDLINE]Related articles

Large rearrangements of the LDL receptor gene and lipid profile in a FH Spanish population.

Chaves FJ, Real JT, García-García AB, Puig O, Ordovas JM, Ascaso JF, Carmena R, Armengod ME.

Eur J Clin Invest. 2001 Apr;31(4):309-17.PMID: 11298777 [PubMed - indexed for MEDLINE]Related articles

Importance of HDL cholesterol levels and the total/ HDL cholesterol ratio as a risk factor for coronary heart disease in molecularly defined heterozygous familial hypercholesterolaemia.

Real JT, Chaves FJ, Martínez-Usó I, García-García AB, Ascaso JF, Carmena R.

Eur Heart J. 2001 Mar;22(6):465-71.PMID: 11237541 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and familial dyslipidaemias.

Ascaso JF, Real JT, Carmena R.

Diabetes Obes Metab. 1999 Nov;1(6):323-30. Review. No abstract available. PMID: 11225648 [PubMed - indexed for MEDLINE]Related articles

[Influence of FH Valencia 1 and 2 mutations of the LDL receptor gene on the response to simvastatin in subjects with molecularly defined heterozygous familial hypercholesterolemia in Spain]

Real JT, Chaves FJ, Civera M, García-García AB, Ascaso JF, Armengod ME, Carmena R.

Med Clin (Barc). 2001 Jan 27;116(3):81-5. Spanish. PMID: 11181283 [PubMed - indexed for MEDLINE]Related articles

Lipoprotein phenotype and insulin resistance in familial combined hyperlipidemia.

Ascaso JF, Real JT, Merchante A, Rodrigo A, Carmena R.

Metabolism. 2000 Dec;49(12):1627-31.PMID: 11145128 [PubMed - indexed for MEDLINE]Related articles

Effect of apolipoprotein E genotype on lipid levels and response to diet in familial hypercholesterolemia.

Carmena-Ramón R, Real JT, Ascaso JF, Ordovás JM, Carmena R.

Nutr Metab Cardiovasc Dis. 2000 Feb;10(1):7-13.PMID: 10812582 [PubMed - indexed for MEDLINE]Related articles

Ciprofibrate effects on carbohydrate and lipid metabolism in type 2 diabetes mellitus subjects.

Hernández-Mijares A, Lluch I, Vizcarra E, Martínez-Triguero ML, Ascaso JF, Carmena R.

Nutr Metab Cardiovasc Dis. 2000 Feb;10(1):1-6.PMID: 10812581 [PubMed - indexed for MEDLINE]Related articles

Plasma Lp(a) values in familial hypercholesterolemia and its relation to coronary heart disease.

Real JT, Ascaso JF, Chaves FJ, Tenés S, Priego MA, Puig O, Armengod ME, Carmena R.

Nutr Metab Cardiovasc Dis. 1999 Feb;9(1):41-4.PMID: 10726108 [PubMed - indexed for MEDLINE]Related articles

[Familial defect of apo B-100 in subjects with clinically diagnosed primary hypercholesterolemia: identification of the first family with this disorder in Spain]

Real JT, Chaves JF, Ascaso JF, Armengod ME, Carmena R.

Med Clin (Barc). 1999 Jun 12;113(1):15-7. Spanish. PMID: 10422071 [PubMed - indexed for MEDLINE]Related articles

Gastroesophageal reflux in diabetes mellitus.

Lluch I, Ascaso JF, Mora F, Minguez M, Peña A, Hernandez A, Benages A.

Am J Gastroenterol. 1999 Apr;94(4):919-24.PMID: 10201457 [PubMed - indexed for MEDLINE]Related articles