PubMed

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel,on behalf of the European LeukemiaNet.

Dohner H, Estey EH, Amadori S, Appelbaum FR, Buchner T, Burnett AK, Dombret H, Fenaux P, Grimwade D, Larson RA, Lo Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz MA, Sierra J, Tallman MS, Lowenberg B, Bloomfield CD.

Blood. 2009 Oct 30. [Epub ahead of print]PMID: 19880497 [PubMed - as supplied by publisher]Related articles

Thomas' Hematopoietic Cell Transplantation.

Appelbaum FR, Forman SJ, Negrin RS, Blume KG.

Eur J Haematol. 2009 Oct 14. [Epub ahead of print] No abstract available. PMID: 19840108 [PubMed - as supplied by publisher]Related articles

Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia.

Chauncey TR, Gundacker H, Shadman M, List AF, Dakhil SR, Erba HP, Slovak ML, Chen IM, Willman CL, Kopecky KJ, Appelbaum FR.

Br J Haematol. 2009 Oct 11. [Epub ahead of print]PMID: 19821823 [PubMed - as supplied by publisher]Related articles

Cord blood transplantation for haematological malignancies: conditioning regimens, double cord transplant and infectious complications.

Delaney C, Gutman JA, Appelbaum FR.

Br J Haematol. 2009 Oct;147(2):207-16.PMID: 19796270 [PubMed - in process]Related articles

Allogeneic hematopoietic cell transplantation after conditioning with 131I-anti-CD45 antibody plus fludarabine and low-dose total body irradiation for elderly patients with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome.

Pagel JM, Gooley TA, Rajendran J, Fisher DR, Wilson WA, Sandmaier BM, Matthews DC, Deeg HJ, Gopal AK, Martin PJ, Storb RF, Press OW, Appelbaum FR.

Blood. 2009 Sep 28. [Epub ahead of print]PMID: 19786617 [PubMed - as supplied by publisher]Related articles

The quality of life of adult survivors of childhood hematopoietic cell transplant.

Sanders JE, Hoffmeister PA, Storer BE, Appelbaum FR, Storb RF, Syrjala KL.

Bone Marrow Transplant. 2009 Aug 31. [Epub ahead of print]PMID: 19718073 [PubMed - as supplied by publisher]Related articles

Low relapse without excessive transplant-related mortality following myeloablative cord blood transplantation for acute leukemia in complete remission: a matched cohort analysis.

Gutman JA, Leisenring W, Appelbaum FR, Woolfrey AE, Delaney C.

Biol Blood Marrow Transplant. 2009 Sep;15(9):1122-9.PMID: 19660726 [PubMed - indexed for MEDLINE]Related articles

Structural and functional alterations of FLT3 in acute myeloid leukemia.

Meshinchi S, Appelbaum FR.

Clin Cancer Res. 2009 Jul 1;15(13):4263-9. Epub 2009 Jun 23. Review.PMID: 19549778 [PubMed - indexed for MEDLINE]Related articles

Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: systematic review and meta-analysis of prospective clinical trials.

Koreth J, Schlenk R, Kopecky KJ, Honda S, Sierra J, Djulbegovic BJ, Wadleigh M, DeAngelo DJ, Stone RM, Sakamaki H, Appelbaum FR, Döhner H, Antin JH, Soiffer RJ, Cutler C.

JAMA. 2009 Jun 10;301(22):2349-61. Review.PMID: 19509382 [PubMed - indexed for MEDLINE]Related articles

Evaluation of NIH consensus criteria for classification of late acute and chronic GVHD.

Vigorito AC, Campregher PV, Storer BE, Carpenter PA, Moravec CK, Kiem HP, Fero ML, Warren EH, Lee SJ, Appelbaum FR, Martin PJ, Flowers ME; National Institutes of Health.

Blood. 2009 Jul 16;114(3):702-8. Epub 2009 May 21.PMID: 19470693 [PubMed - indexed for MEDLINE]Related articles

Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study.

Carnevale-Schianca F, Leisenring W, Martin PJ, Furlong T, Schoch G, Anasetti C, Appelbaum FR, Carpenter PA, Deeg HJ, Kiem HP, Storb R, McDonald GB, Nash RA.

Biol Blood Marrow Transplant. 2009 Jun;15(6):749-56.PMID: 19450760 [PubMed - indexed for MEDLINE]Related articles

Therapy with mycophenolate mofetil for refractory acute and chronic GVHD.

Furlong T, Martin P, Flowers ME, Carnevale-Schianca F, Yatscoff R, Chauncey T, Appelbaum FR, Deeg HJ, Doney K, Witherspoon R, Storer B, Sullivan KM, Storb R, Nash RA.

Bone Marrow Transplant. 2009 Apr 20. [Epub ahead of print]PMID: 19377515 [PubMed - as supplied by publisher]Related articles

Personalized dosing of cyclophosphamide in the total body irradiation-cyclophosphamide conditioning regimen: a phase II trial in patients with hematologic malignancy.

McCune JS, Batchelder A, Guthrie KA, Witherspoon R, Appelbaum FR, Phillips B, Vicini P, Salinger DH, McDonald GB.

Clin Pharmacol Ther. 2009 Jun;85(6):615-22. Epub 2009 Mar 18.PMID: 19295506 [PubMed - indexed for MEDLINE]Related articles

Beneficial and harmful effects of anthracyclines in the treatment of childhood acute lymphoblastic leukaemia: a systematic review and meta-analysis.

Childhood Acute Lymphoblastic Leukaemia Collaborative Group (CALLCG).

Br J Haematol. 2009 May;145(3):376-88. Epub 2009 Feb 22. Review.PMID: 19236609 [PubMed - indexed for MEDLINE]Related articles

Acute myeloid leukemia.

O'Donnell MR, Appelbaum FR, Coutre SE, Damon LE, Erba HP, Foran J, Lancet J, Maness LJ, Marcucci G, Maslak PG, Millenson M, Moore JO, Ravandi F, Schuening F, Shami P, Smith BD, Stone RM, Tallman MS, Wang E, White FL.

J Natl Compr Canc Netw. 2008 Nov;6(10):962-93. Review. No abstract available. PMID: 19176196 [PubMed - indexed for MEDLINE]Related articles

Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.

Pagel JM, Matthews DC, Kenoyer A, Hamlin DK, Wilbur DS, Fisher DR, Gopal AK, Lin Y, Saganic L, Appelbaum FR, Press OW.

Cancer Res. 2009 Jan 1;69(1):185-92.PMID: 19118002 [PubMed - indexed for MEDLINE]Related articles

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia when a matched related donor is not available.

Appelbaum FR.

Hematology Am Soc Hematol Educ Program. 2008:412-7.PMID: 19074118 [PubMed - indexed for MEDLINE]Related articlesFree article

What is the impact of hematopoietic cell transplantation (HCT) for older adults with acute myeloid leukemia (AML)?

Appelbaum FR.

Best Pract Res Clin Haematol. 2008 Dec;21(4):667-75. Review.PMID: 19041606 [PubMed - indexed for MEDLINE]Related articles

Long-term outcome of patients with multiple myeloma after autologous hematopoietic cell transplantation and nonmyeloablative allografting.

Rotta M, Storer BE, Sahebi F, Shizuru JA, Bruno B, Lange T, Agura ED, McSweeney PA, Pulsipher MA, Hari P, Maziarz RT, Chauncey TR, Appelbaum FR, Sorror ML, Bensinger W, Sandmaier BM, Storb RF, Maloney DG.

Blood. 2009 Apr 2;113(14):3383-91. Epub 2008 Nov 17.PMID: 19015394 [PubMed - indexed for MEDLINE]Related articles

Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes.

Mielcarek M, Storer BE, Boeckh M, Carpenter PA, McDonald GB, Deeg HJ, Nash RA, Flowers ME, Doney K, Lee S, Marr KA, Furlong T, Storb R, Appelbaum FR, Martin PJ.

Blood. 2009 Mar 26;113(13):2888-94. Epub 2008 Nov 10.PMID: 19001082 [PubMed - indexed for MEDLINE]Related articles

Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.

Becker PS, Kopecky KJ, Wilks AN, Chien S, Harlan JM, Willman CL, Petersdorf SH, Stirewalt DL, Papayannopoulou T, Appelbaum FR.

Blood. 2009 Jan 22;113(4):866-74. Epub 2008 Oct 16.PMID: 18927435 [PubMed - indexed for MEDLINE]Related articles

Thyroid function following hematopoietic cell transplantation in children: 30 years' experience.

Sanders JE, Hoffmeister PA, Woolfrey AE, Carpenter PA, Storer BE, Storb RF, Appelbaum FR.

Blood. 2009 Jan 8;113(2):306-8. Epub 2008 Oct 6.PMID: 18838614 [PubMed - indexed for MEDLINE]Related articles

Generation of HIV-1-specific CD8+ cell responses following allogeneic hematopoietic cell transplantation.

Woolfrey AE, Malhotra U, Harrington RD, McNevin J, Manley TJ, Riddell SR, Coombs RW, Appelbaum FR, Corey L, Storb R.

Blood. 2008 Oct 15;112(8):3484-7. Epub 2008 Aug 12.PMID: 18698002 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.

Stirewalt DL, Choi YE, Sharpless NE, Pogosova-Agadjanyan EL, Cronk MR, Yukawa M, Larson EB, Wood BL, Appelbaum FR, Radich JP, Heimfeld S.

Leukemia. 2009 Feb;23(2):391-3. Epub 2008 Jul 3. No abstract available. Erratum in: Leukemia. 2009 Feb;23(2):430. PMID: 18596738 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic cell transplantation for non-Hodgkin's lymphoma: yesterday, today, and tomorrow.

Appelbaum FR.

J Clin Oncol. 2008 Jun 20;26(18):2927-9. No abstract available. PMID: 18565876 [PubMed - indexed for MEDLINE]Related articles

Pretransplant neutropenia is associated with poor-risk cytogenetic features and increased infection-related mortality in patients with myelodysplastic syndromes.

Scott BL, Park JY, Deeg HJ, Marr KA, Boeckh M, Chauncey TR, Appelbaum FR, Storb R, Storer BE.

Biol Blood Marrow Transplant. 2008 Jul;14(7):799-806.PMID: 18541200 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of utility of chimerism studies obtained 2-3 months after myeloablative hematopoietic cell transplantation for ALL.

Doney K, Loken M, Bryant E, Smith A, Appelbaum F.

Bone Marrow Transplant. 2008 Aug;42(4):271-4. Epub 2008 May 26.PMID: 18500370 [PubMed - indexed for MEDLINE]Related articles

Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.

Furlong T, Kiem HP, Appelbaum FR, Carpenter PA, Deeg HJ, Doney K, Flowers ME, Mielcarek M, Nash RA, Storb R, Martin PJ.

Biol Blood Marrow Transplant. 2008 May;14(5):531-7.PMID: 18410895 [PubMed - indexed for MEDLINE]Related articlesFree article

Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML).

Appelbaum FR.

Best Pract Res Clin Haematol. 2008 Mar;21(1):85-92. Review.PMID: 18342816 [PubMed - indexed for MEDLINE]Related articles

Simultaneously targeting CD45 significantly increases cytotoxicity of the anti-CD33 immunoconjugate, gemtuzumab ozogamicin, against acute myeloid leukemia (AML) cells and improves survival of mice bearing human AML xenografts.

Walter RB, Boyle KM, Appelbaum FR, Bernstein ID, Pagel JM.

Blood. 2008 May 1;111(9):4813-6. Epub 2008 Mar 7.PMID: 18326813 [PubMed - indexed for MEDLINE]Related articlesFree article

Indications for hematopoietic cell transplantation in acute leukemia.

Davies SM, Rowe JM, Appelbaum FR.

Biol Blood Marrow Transplant. 2008 Jan;14(1 Suppl 1):154-64. Review. Erratum in: Biol Blood Marrow Transplant. 2008 Nov;14(11):1317-8. PMID: 18162237 [PubMed - indexed for MEDLINE]Related articles

Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: results of Southwest Oncology Group 9400 study.

Pullarkat V, Slovak ML, Kopecky KJ, Forman SJ, Appelbaum FR.

Blood. 2008 Mar 1;111(5):2563-72. Epub 2007 Dec 21.PMID: 18156492 [PubMed - indexed for MEDLINE]Related articlesFree article

Eradication of disseminated leukemia in a syngeneic murine leukemia model using pretargeted anti-CD45 radioimmunotherapy.

Pagel JM, Hedin N, Drouet L, Wood BL, Pantelias A, Lin Y, Hamlin DK, Wilbur DS, Gopal AK, Green D, Appelbaum FR, Press OW.

Blood. 2008 Feb 15;111(4):2261-8. Epub 2007 Nov 27.PMID: 18042793 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic-cell transplantation at 50.

Appelbaum FR.

N Engl J Med. 2007 Oct 11;357(15):1472-5. No abstract available. PMID: 17928594 [PubMed - indexed for MEDLINE]Related articles

Hematopoietic cell transplantation specific comorbidity index as an outcome predictor for patients with acute myeloid leukemia in first remission: combined FHCRC and MDACC experiences.

Sorror ML, Giralt S, Sandmaier BM, De Lima M, Shahjahan M, Maloney DG, Deeg HJ, Appelbaum FR, Storer B, Storb R.

Blood. 2007 Dec 15;110(13):4606-13. Epub 2007 Sep 14.PMID: 17873123 [PubMed - indexed for MEDLINE]Related articlesFree article

Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation.

Sorror ML, Sandmaier BM, Storer BE, Maris MB, Baron F, Maloney DG, Scott BL, Deeg HJ, Appelbaum FR, Storb R.

J Clin Oncol. 2007 Sep 20;25(27):4246-54. Epub 2007 Aug 27.PMID: 17724349 [PubMed - indexed for MEDLINE]Related articles

Phase II evaluation of an intensified induction therapy with standard daunomycin and cytarabine followed by high dose cytarabine for adults with previously untreated acute myeloid leukemia: a Southwest Oncology Group study (SWOG-9500).

Petersdorf SH, Rankin C, Head DR, Terebelo HR, Willman CL, Balcerzak SP, Karnad AB, Dakhil SR, Appelbaum FR.

Am J Hematol. 2007 Dec;82(12):1056-62.PMID: 17696203 [PubMed - indexed for MEDLINE]Related articles

Graft-versus-host disease: a surge of developments.

Riddell SR, Appelbaum FR.

PLoS Med. 2007 Jul;4(7):e198. Review. No abstract available. PMID: 17622190 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute myeloid leukemia arising from myelodysplastic syndrome: similar outcomes in patients with de novo disease and disease following prior therapy or antecedent hematologic disorders.

Chang C, Storer BE, Scott BL, Bryant EM, Shulman HM, Flowers ME, Sandmaier BM, Witherspoon RP, Nash RA, Sanders JE, Bedalov A, Hansen JA, Clurman BE, Storb R, Appelbaum FR, Deeg HJ.

Blood. 2007 Aug 15;110(4):1379-87. Epub 2007 May 8.PMID: 17488876 [PubMed - indexed for MEDLINE]Related articlesFree article

Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.

DeAngelo DJ, Yu D, Johnson JL, Coutre SE, Stone RM, Stopeck AT, Gockerman JP, Mitchell BS, Appelbaum FR, Larson RA.

Blood. 2007 Jun 15;109(12):5136-42. Epub 2007 Mar 7.PMID: 17344466 [PubMed - indexed for MEDLINE]Related articlesFree article

Hematopoietic cell transplantation from unrelated donors for treatment of patients with acute myeloid leukemia in first complete remission.

Appelbaum FR.

Best Pract Res Clin Haematol. 2007 Mar;20(1):67-75. Review.PMID: 17336256 [PubMed - indexed for MEDLINE]Related articles

Hematopoietic cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemia.

Kerbauy DM, Gooley TA, Sale GE, Flowers ME, Doney KC, Georges GE, Greene JE, Linenberger M, Petersdorf E, Sandmaier BM, Scott BL, Sorror M, Stirewalt DL, Stewart FM, Witherspoon RP, Storb R, Appelbaum FR, Deeg HJ.

Biol Blood Marrow Transplant. 2007 Mar;13(3):355-65.PMID: 17317589 [PubMed - indexed for MEDLINE]Related articles

Marrow fibrosis as a risk factor for posttransplantation outcome in patients with advanced myelodysplastic syndrome or acute myeloid leukemia with multilineage dysplasia.

Scott BL, Storer BE, Greene JE, Hackman RC, Appelbaum FR, Deeg HJ.

Biol Blood Marrow Transplant. 2007 Mar;13(3):345-54.PMID: 17317588 [PubMed - indexed for MEDLINE]Related articles

High-dose [131I]tositumomab (anti-CD20) radioimmunotherapy and autologous hematopoietic stem-cell transplantation for adults > or = 60 years old with relapsed or refractory B-cell lymphoma.

Gopal AK, Rajendran JG, Gooley TA, Pagel JM, Fisher DR, Petersdorf SH, Maloney DG, Eary JF, Appelbaum FR, Press OW.

J Clin Oncol. 2007 Apr 10;25(11):1396-402. Epub 2007 Feb 20.PMID: 17312330 [PubMed - indexed for MEDLINE]Related articles

Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997.

Flinn IW, Neuberg DS, Grever MR, Dewald GW, Bennett JM, Paietta EM, Hussein MA, Appelbaum FR, Larson RA, Moore DF Jr, Tallman MS.

J Clin Oncol. 2007 Mar 1;25(7):793-8. Epub 2007 Feb 5.PMID: 17283364 [PubMed - indexed for MEDLINE]Related articles

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

Grever MR, Lucas DM, Dewald GW, Neuberg DS, Reed JC, Kitada S, Flinn IW, Tallman MS, Appelbaum FR, Larson RA, Paietta E, Jelinek DF, Gribben JG, Byrd JC.

J Clin Oncol. 2007 Mar 1;25(7):799-804. Epub 2007 Feb 5.PMID: 17283363 [PubMed - indexed for MEDLINE]Related articles

CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy.

Walter RB, Gooley TA, van der Velden VH, Loken MR, van Dongen JJ, Flowers DA, Bernstein ID, Appelbaum FR.

Blood. 2007 May 15;109(10):4168-70. Epub 2007 Jan 16.PMID: 17227830 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.

Kornblau SM, Banker DE, Stirewalt D, Shen D, Lemker E, Verstovsek S, Estrov Z, Faderl S, Cortes J, Beran M, Jackson CE, Chen W, Estey E, Appelbaum FR.

Blood. 2007 Apr 1;109(7):2999-3006.PMID: 17158228 [PubMed - indexed for MEDLINE]Related articlesFree article

Prophylactic administration of imatinib after hematopoietic cell transplantation for high-risk Philadelphia chromosome-positive leukemia.

Carpenter PA, Snyder DS, Flowers ME, Sanders JE, Gooley TA, Martin PJ, Appelbaum FR, Radich JP.

Blood. 2007 Apr 1;109(7):2791-3.PMID: 17119111 [PubMed - indexed for MEDLINE]Related articlesFree article

End points to establish the efficacy of new agents in the treatment of acute leukemia.

Appelbaum FR, Rosenblum D, Arceci RJ, Carroll WL, Breitfeld PP, Forman SJ, Larson RA, Lee SJ, Murphy SB, O'Brien S, Radich J, Scher NS, Smith FO, Stone RM, Tallman MS.

Blood. 2007 Mar 1;109(5):1810-6. Epub 2006 Nov 9.PMID: 17095617 [PubMed - indexed for MEDLINE]Related articlesFree article