PubMed

Mechanisms of Myocardial Regeneration.

Hosoda T, Kajstura J, Leri A, Anversa P.

Circ J. 2009 Nov 17. [Epub ahead of print]PMID: 19920358 [PubMed - as supplied by publisher]Related articlesFree article

Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.

D'Alessandro DA, Kajstura J, Hosoda T, Gatti A, Bello R, Mosna F, Bardelli S, Zheng H, D'Amario D, Padin-Iruegas ME, Carvalho AB, Rota M, Zembala MO, Stern D, Rimoldi O, Urbanek K, Michler RE, Leri A, Anversa P.

Circ Res. 2009 Nov 20;105(11):1128-40. Epub 2009 Oct 8.PMID: 19815820 [PubMed - in process]Related articles

Clonality of mouse and human cardiomyogenesis in vivo.

Hosoda T, D'Amario D, Cabral-Da-Silva MC, Zheng H, Padin-Iruegas ME, Ogorek B, Ferreira-Martins J, Yasuzawa-Amano S, Amano K, Ide-Iwata N, Cheng W, Rota M, Urbanek K, Kajstura J, Anversa P, Leri A.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17169-74. Epub 2009 Sep 17.PMID: 19805158 [PubMed - in process]Related articles

Spontaneous calcium oscillations regulate human cardiac progenitor cell growth.

Ferreira-Martins J, Rondon-Clavo C, Tugal D, Korn JA, Rizzi R, Padin-Iruegas ME, Ottolenghi S, De Angelis A, Urbanek K, Ide-Iwata N, D'Amario D, Hosoda T, Leri A, Kajstura J, Anversa P, Rota M.

Circ Res. 2009 Oct 9;105(8):764-74. Epub 2009 Sep 10.PMID: 19745162 [PubMed - in process]Related articles

Identification of a coronary vascular progenitor cell in the human heart.

Bearzi C, Leri A, Lo Monaco F, Rota M, Gonzalez A, Hosoda T, Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA, Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15885-90. Epub 2009 Aug 27.PMID: 19717420 [PubMed - indexed for MEDLINE]Related articles

Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction.

Padin-Iruegas ME, Misao Y, Davis ME, Segers VF, Esposito G, Tokunou T, Urbanek K, Hosoda T, Rota M, Anversa P, Leri A, Lee RT, Kajstura J.

Circulation. 2009 Sep 8;120(10):876-87. Epub 2009 Aug 24.PMID: 19704095 [PubMed - indexed for MEDLINE]Related articles

Multipotent progenitor cells are present in human peripheral blood.

Cesselli D, Beltrami AP, Rigo S, Bergamin N, D'Aurizio F, Verardo R, Piazza S, Klaric E, Fanin R, Toffoletto B, Marzinotto S, Mariuzzi L, Finato N, Pandolfi M, Leri A, Schneider C, Beltrami CA, Anversa P.

Circ Res. 2009 May 22;104(10):1225-34. Epub 2009 Apr 23.PMID: 19390058 [PubMed - indexed for MEDLINE]Related articles

Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice.

Liu X, Ramjiganesh T, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF Jr, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA.

Circulation. 2009 Jan 20;119(2):261-8. Epub 2008 Dec 31.PMID: 19118250 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines and myocardial regeneration: a novel treatment option for acute myocardial infarction.

Srinivas G, Anversa P, Frishman WH.

Cardiol Rev. 2009 Jan-Feb;17(1):1-9. Review.PMID: 19092364 [PubMed - indexed for MEDLINE]Related articles

Notch1 regulates the fate of cardiac progenitor cells.

Boni A, Urbanek K, Nascimbene A, Hosoda T, Zheng H, Delucchi F, Amano K, Gonzalez A, Vitale S, Ojaimi C, Rizzi R, Bolli R, Yutzey KE, Rota M, Kajstura J, Anversa P, Leri A.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15529-34. Epub 2008 Oct 1.PMID: 18832173 [PubMed - indexed for MEDLINE]Related articlesFree article

Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.

Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R Jr, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, Magnuson N, Houser SR, Anversa P, Sussman MA.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13889-94. Epub 2008 Sep 10.PMID: 18784362 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac stem cells and myocardial disease.

Kajstura J, Urbanek K, Rota M, Bearzi C, Hosoda T, Bolli R, Anversa P, Leri A.

J Mol Cell Cardiol. 2008 Oct;45(4):505-13. Epub 2008 Jun 13. Review.PMID: 18598700 [PubMed - indexed for MEDLINE]Related articles

Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function.

Rota M, Padin-Iruegas ME, Misao Y, De Angelis A, Maestroni S, Ferreira-Martins J, Fiumana E, Rastaldo R, Arcarese ML, Mitchell TS, Boni A, Bolli R, Urbanek K, Hosoda T, Anversa P, Leri A, Kajstura J.

Circ Res. 2008 Jul 3;103(1):107-16. Epub 2008 Jun 12.PMID: 18556576 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge.

Siddiqi S, Gude N, Hosoda T, Muraski J, Rubio M, Emmanuel G, Fransioli J, Vitale S, Parolin C, D'Amario D, Schaefer E, Kajstura J, Leri A, Anversa P, Sussman MA.

Circ Res. 2008 Jul 3;103(1):89-97. Epub 2008 Jun 2.PMID: 18519946 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial regeneration and stem cell repair.

Leri A, Kajstura J, Anversa P, Frishman WH.

Curr Probl Cardiol. 2008 Mar;33(3):91-153. Review.PMID: 18243902 [PubMed - indexed for MEDLINE]Related articles

Formation of large coronary arteries by cardiac progenitor cells.

Tillmanns J, Rota M, Hosoda T, Misao Y, Esposito G, Gonzalez A, Vitale S, Parolin C, Yasuzawa-Amano S, Muraski J, De Angelis A, Lecapitaine N, Siggins RW, Loredo M, Bearzi C, Bolli R, Urbanek K, Leri A, Kajstura J, Anversa P.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1668-73. Epub 2008 Jan 23.PMID: 18216245 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.

Gonzalez A, Rota M, Nurzynska D, Misao Y, Tillmanns J, Ojaimi C, Padin-Iruegas ME, Müller P, Esposito G, Bearzi C, Vitale S, Dawn B, Sanganalmath SK, Baker M, Hintze TH, Bolli R, Urbanek K, Hosoda T, Anversa P, Kajstura J, Leri A.

Circ Res. 2008 Mar 14;102(5):597-606. Epub 2008 Jan 17.PMID: 18202313 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction.

Ren J, Duan J, Thomas DP, Yang X, Sreejayan N, Sowers JR, Leri A, Kajstura J, Gao F, Anversa P.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R793-802. Epub 2008 Jan 16.PMID: 18199585 [PubMed - indexed for MEDLINE]Related articles

Pim-1 regulates cardiomyocyte survival downstream of Akt.

Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, Glembotski CC, Leri A, Kajstura J, Magnuson N, Berns A, Beretta RM, Houser SR, Schaefer EM, Anversa P, Sussman MA.

Nat Med. 2007 Dec;13(12):1467-75. Epub 2007 Nov 25. Erratum in: Nat Med. 2008 Mar;14(3):350. PMID: 18037896 [PubMed - indexed for MEDLINE]Related articles

Bone marrow cells adopt the cardiomyogenic fate in vivo.

Rota M, Kajstura J, Hosoda T, Bearzi C, Vitale S, Esposito G, Iaffaldano G, Padin-Iruegas ME, Gonzalez A, Rizzi R, Small N, Muraski J, Alvarez R, Chen X, Urbanek K, Bolli R, Houser SR, Leri A, Sussman MA, Anversa P.

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17783-8. Epub 2007 Oct 26.PMID: 17965233 [PubMed - indexed for MEDLINE]Related articlesFree article

Human cardiac stem cells.

Bearzi C, Rota M, Hosoda T, Tillmanns J, Nascimbene A, De Angelis A, Yasuzawa-Amano S, Trofimova I, Siggins RW, Lecapitaine N, Cascapera S, Beltrami AP, D'Alessandro DA, Zias E, Quaini F, Urbanek K, Michler RE, Bolli R, Kajstura J, Leri A, Anversa P.

Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14068-73. Epub 2007 Aug 20.PMID: 17709737 [PubMed - indexed for MEDLINE]Related articlesFree article

The young mouse heart is composed of myocytes heterogeneous in age and function.

Rota M, Hosoda T, De Angelis A, Arcarese ML, Esposito G, Rizzi R, Tillmanns J, Tugal D, Musso E, Rimoldi O, Bearzi C, Urbanek K, Anversa P, Leri A, Kajstura J.

Circ Res. 2007 Aug 17;101(4):387-99. Epub 2007 Jun 29.PMID: 17601802 [PubMed - indexed for MEDLINE]Related articlesFree article

Heart failure and regenerative cardiology.

Leri A, Hosoda T, Kajstura J, Anversa P.

Regen Med. 2006 Mar;1(2):153-9. No abstract available. PMID: 17465797 [PubMed - indexed for MEDLINE]Related articles

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

Camici GG, Schiavoni M, Francia P, Bachschmid M, Martin-Padura I, Hersberger M, Tanner FC, Pelicci P, Volpe M, Anversa P, Lüscher TF, Cosentino F.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5217-22. Epub 2007 Mar 14.PMID: 17360381 [PubMed - indexed for MEDLINE]Related articlesFree article

If I can stop one heart from breaking.

Anversa P, Kajstura J, Leri A.

Circulation. 2007 Feb 20;115(7):829-32. No abstract available. PMID: 17309932 [PubMed - indexed for MEDLINE]Related articlesFree article

Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.

Chen X, Wilson RM, Kubo H, Berretta RM, Harris DM, Zhang X, Jaleel N, MacDonnell SM, Bearzi C, Tillmanns J, Trofimova I, Hosoda T, Mosna F, Cribbs L, Leri A, Kajstura J, Anversa P, Houser SR.

Circ Res. 2007 Mar 2;100(4):536-44. Epub 2007 Feb 1.PMID: 17272809 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial Regeneration by Exogenous and Endogenous Progenitor Cells.

Leri A, Hosoda T, Rota M, Kajstura J, Anversa P.

Drug Discov Today Dis Mech. 2007;4(3):197-203.PMID: 19081818 [PubMed]Related articlesFree article

Concise review: stem cells, myocardial regeneration, and methodological artifacts.

Anversa P, Leri A, Rota M, Hosoda T, Bearzi C, Urbanek K, Kajstura J, Bolli R.

Stem Cells. 2007 Mar;25(3):589-601. Epub 2006 Nov 22. Review.PMID: 17124006 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage.

Li Q, Wu S, Li SY, Lopez FL, Du M, Kajstura J, Anversa P, Ren J.

Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1398-403. Epub 2006 Nov 3.PMID: 17085535 [PubMed - indexed for MEDLINE]Related articlesFree article

The telomere-telomerase axis and the heart.

Kajstura J, Rota M, Urbanek K, Hosoda T, Bearzi C, Anversa P, Bolli R, Leri A.

Antioxid Redox Signal. 2006 Nov-Dec;8(11-12):2125-41. Review.PMID: 17034355 [PubMed - indexed for MEDLINE]Related articles

[Bone marrow cells and cardiac repair]

Leri A, Kajstura J, Anversa P.

Arq Bras Cardiol. 2006 Aug;87(2):71-2. Review. Portuguese. No abstract available. PMID: 16951821 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy.

Tsujita Y, Muraski J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11946-51. Epub 2006 Aug 1.PMID: 16882732 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population.

Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E, Anversa P, Sussman MA.

Circ Res. 2006 Aug 18;99(4):381-8. Epub 2006 Jul 13.PMID: 16840722 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene.

Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas ME, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Lüscher TF, Pelicci PG, Anversa P, Leri A, Kajstura J.

Circ Res. 2006 Jul 7;99(1):42-52. Epub 2006 Jun 8.PMID: 16763167 [PubMed - indexed for MEDLINE]Related articlesFree article

Stem cell niches in the adult mouse heart.

Urbanek K, Cesselli D, Rota M, Nascimbene A, De Angelis A, Hosoda T, Bearzi C, Boni A, Bolli R, Kajstura J, Anversa P, Leri A.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9226-31. Epub 2006 Jun 5.PMID: 16754876 [PubMed - indexed for MEDLINE]Related articlesFree article

Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction.

Davis ME, Hsieh PC, Takahashi T, Song Q, Zhang S, Kamm RD, Grodzinsky AJ, Anversa P, Lee RT.

Proc Natl Acad Sci U S A. 2006 May 23;103(21):8155-60. Epub 2006 May 12.PMID: 16698918 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac regeneration.

Anversa P, Leri A, Kajstura J.

J Am Coll Cardiol. 2006 May 2;47(9):1769-76. Epub 2006 Apr 17. Review.PMID: 16682300 [PubMed - indexed for MEDLINE]Related articles

Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function.

Dawn B, Guo Y, Rezazadeh A, Huang Y, Stein AB, Hunt G, Tiwari S, Varma J, Gu Y, Prabhu SD, Kajstura J, Anversa P, Ildstad ST, Bolli R.

Circ Res. 2006 Apr 28;98(8):1098-105. Epub 2006 Mar 23.PMID: 16556872 [PubMed - indexed for MEDLINE]Related articlesFree article

Life and death of cardiac stem cells: a paradigm shift in cardiac biology.

Anversa P, Kajstura J, Leri A, Bolli R.

Circulation. 2006 Mar 21;113(11):1451-63. Review. No abstract available. PMID: 16549650 [PubMed - indexed for MEDLINE]Related articlesFree article

Cause of death: suicide.

Kajstura J, Bolli R, Sonnenblick EH, Anversa P, Leri A.

J Mol Cell Cardiol. 2006 Apr;40(4):425-37. Epub 2006 Feb 28. Review.PMID: 16513132 [PubMed - indexed for MEDLINE]Related articles

Endothelial progenitor cells: neovascularization or more?

Kajstura J, Leri A, Bolli R, Anversa P.

J Mol Cell Cardiol. 2006 Jan;40(1):1-8. No abstract available. Erratum in: J Mol Cell Cardiol. 2006 Jan;40(1):9. PMID: 16321397 [PubMed - indexed for MEDLINE]Related articles

Nuclear targeting of Akt enhances ventricular function and myocyte contractility.

Rota M, Boni A, Urbanek K, Padin-Iruegas ME, Kajstura TJ, Fiore G, Kubo H, Sonnenblick EH, Musso E, Houser SR, Leri A, Sussman MA, Anversa P.

Circ Res. 2005 Dec 9;97(12):1332-41. Epub 2005 Nov 17.PMID: 16293788 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial aging--a stem cell problem.

Anversa P, Rota M, Urbanek K, Hosoda T, Sonnenblick EH, Leri A, Kajstura J, Bolli R.

Basic Res Cardiol. 2005 Nov;100(6):482-93. Review.PMID: 16237507 [PubMed - indexed for MEDLINE]Related articles

Cardiac stem cells and mechanisms of myocardial regeneration.

Leri A, Kajstura J, Anversa P.

Physiol Rev. 2005 Oct;85(4):1373-416. Review.PMID: 16183916 [PubMed - indexed for MEDLINE]Related articlesFree article

Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation.

Limana F, Germani A, Zacheo A, Kajstura J, Di Carlo A, Borsellino G, Leoni O, Palumbo R, Battistini L, Rastaldo R, Müller S, Pompilio G, Anversa P, Bianchi ME, Capogrossi MC.

Circ Res. 2005 Oct 14;97(8):e73-83. Epub 2005 Sep 15.PMID: 16166556 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.

Urbanek K, Rota M, Cascapera S, Bearzi C, Nascimbene A, De Angelis A, Hosoda T, Chimenti S, Baker M, Limana F, Nurzynska D, Torella D, Rotatori F, Rastaldo R, Musso E, Quaini F, Leri A, Kajstura J, Anversa P.

Circ Res. 2005 Sep 30;97(7):663-73. Epub 2005 Sep 1. Erratum in: Circ Res. 2006 Feb 17;98(3):e27. PMID: 16141414 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging and longevity: the IGF-1 enigma.

Anversa P.

Circ Res. 2005 Sep 2;97(5):411-4. No abstract available. PMID: 16141115 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac stem cells and myocardial regeneration.

Nadal-Ginard B, Anversa P, Kajstura J, Leri A.

Novartis Found Symp. 2005;265:142-54; discussion 155-7, 204-11. Review.PMID: 16050255 [PubMed - indexed for MEDLINE]Related articles

PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury.

Nagoshi T, Matsui T, Aoyama T, Leri A, Anversa P, Li L, Ogawa W, del Monte F, Gwathmey JK, Grazette L, Hemmings BA, Kass DA, Champion HC, Rosenzweig A.

J Clin Invest. 2005 Aug;115(8):2128-38. Epub 2005 Jul 7. Erratum in: J Clin Invest. 2006 Feb;116(2):548. Hemmings, Brian [corrected to Hemmings, Brian A]. PMID: 16007268 [PubMed - indexed for MEDLINE]Related articlesFree article

Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function.

Linke A, Müller P, Nurzynska D, Casarsa C, Torella D, Nascimbene A, Castaldo C, Cascapera S, Böhm M, Quaini F, Urbanek K, Leri A, Hintze TH, Kajstura J, Anversa P.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8966-71. Epub 2005 Jun 10.PMID: 15951423 [PubMed - indexed for MEDLINE]Related articlesFree article