PubMed

A systems biology perspective on sVEGFR1: its biological function, pathogenic role & therapeutic use.

Wu FT, Stefanini MO, Gabhann FM, Kontos CD, Annex BH, Popel AS.

J Cell Mol Med. 2009 Oct 16. [Epub ahead of print]PMID: 19840194 [PubMed - as supplied by publisher]Related articles

Plasma nitrite response and arterial reactivity differentiate vascular health and performance.

Allen JD, Miller EM, Schwark E, Robbins JL, Duscha BD, Annex BH.

Nitric Oxide. 2009 Jun;20(4):231-7. Epub 2009 Jan 25.PMID: 19371597 [PubMed - indexed for MEDLINE]Related articles

Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport.

Wu FT, Stefanini MO, Gabhann FM, Kontos CD, Annex BH, Popel AS.

Physiol Genomics. 2009 Jun 10;38(1):29-41. Epub 2009 Apr 7.PMID: 19351908 [PubMed - indexed for MEDLINE]Related articles

A sex-specific relationship between capillary density and anaerobic threshold.

Robbins JL, Duscha BD, Bensimhon DR, Wasserman K, Hansen JE, Houmard JA, Annex BH, Kraus WE.

J Appl Physiol. 2009 Apr;106(4):1181-6. Epub 2009 Jan 22.PMID: 19164774 [PubMed - indexed for MEDLINE]Related articles

Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women.

Nicklas BJ, Leng I, Delbono O, Kitzman DW, Marsh AP, Hundley WG, Lyles MF, O'Rourke KS, Annex BH, Kraus WE.

Aging Clin Exp Res. 2008 Aug;20(4):302-9.PMID: 18852542 [PubMed - indexed for MEDLINE]Related articles

Myocyte specific overexpression of myoglobin impairs angiogenesis after hind-limb ischemia.

Hazarika S, Angelo M, Li Y, Aldrich AJ, Odronic SI, Yan Z, Stamler JS, Annex BH.

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2144-50. Epub 2008 Sep 25.PMID: 18818418 [PubMed - indexed for MEDLINE]Related articles

Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.

Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD.

J Am Coll Cardiol. 2008 Jul 29;52(5):387-93.PMID: 18652948 [PubMed - indexed for MEDLINE]Related articlesFree article

A VEGF trap inhibits the beneficial effect of bFGF on vasoreactivity in corporal tissues of hypercholesterolemic rabbits.

Xie D, Findley CM, Greenfield JM, Pippen AM, Kontos CD, Donatucci CF, Annex BH.

J Sex Med. 2008 Sep;5(9):2069-78. Epub 2008 Jul 15.PMID: 18637998 [PubMed - indexed for MEDLINE]Related articles

Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia.

Powell RJ, Simons M, Mendelsohn FO, Daniel G, Henry TD, Koga M, Morishita R, Annex BH.

Circulation. 2008 Jul 1;118(1):58-65. Epub 2008 Jun 16.PMID: 18559703 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults.

Huffman KM, Slentz CA, Johnson JL, Samsa GP, Duscha BD, Tanner CJ, Annex BH, Houmard JA, Kraus WE.

Metabolism. 2008 Jul;57(7):888-95.PMID: 18555828 [PubMed - indexed for MEDLINE]Related articlesFree article

The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.

Kappas NC, Zeng G, Chappell JC, Kearney JB, Hazarika S, Kallianos KG, Patterson C, Annex BH, Bautch VL.

J Cell Biol. 2008 Jun 2;181(5):847-58. Epub 2008 May 26.PMID: 18504303 [PubMed - indexed for MEDLINE]Related articlesFree article

High cholesterol feeding in C57/Blc6 mice alters expression within the VEGF receptor-ligand family in corporal tissue.

Xie D, Hazarika S, Andrich AJ, Padgett ME, Kontos CD, Donatucci CF, Annex BH.

J Sex Med. 2008 May;5(5):1137-48.PMID: 18439153 [PubMed - indexed for MEDLINE]Related articles

A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia.

Dokun AO, Keum S, Hazarika S, Li Y, Lamonte GM, Wheeler F, Marchuk DA, Annex BH.

Circulation. 2008 Mar 4;117(9):1207-15. Epub 2008 Feb 19.PMID: 18285563 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired angiogenesis following hind-limb ischemia in diabetes mellitus mice.

Li YJ, Guan H, Hazarika S, Liu CW, Annex BH.

Chin Med Sci J. 2007 Dec;22(4):232-7.PMID: 18246670 [PubMed - indexed for MEDLINE]Related articles

Growth factors for therapeutic angiogenesis in hypercholesterolemic erectile dysfunction.

Xie D, Annex BH, Donatucci CF.

Asian J Androl. 2008 Jan;10(1):23-7. Review.PMID: 18087640 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased levels of apoptosis in gastrocnemius skeletal muscle in patients with peripheral arterial disease.

Mitchell RG, Duscha BD, Robbins JL, Redfern SI, Chung J, Bensimhon DR, Kraus WE, Hiatt WR, Regensteiner JG, Annex BH.

Vasc Med. 2007 Nov;12(4):285-90.PMID: 18048464 [PubMed - indexed for MEDLINE]Related articles

Is a simple biomarker for peripheral arterial disease on the horizon?

Annex BH.

Circulation. 2007 Sep 18;116(12):1346-8. No abstract available. PMID: 17875981 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1.

Hazarika S, Dokun AO, Li Y, Popel AS, Kontos CD, Annex BH.

Circ Res. 2007 Oct 26;101(9):948-56. Epub 2007 Sep 6.PMID: 17823371 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth factors for therapeutic angiogenesis in peripheral arterial disease.

Jones WS, Annex BH.

Curr Opin Cardiol. 2007 Sep;22(5):458-63. Review.PMID: 17762548 [PubMed - indexed for MEDLINE]Related articles

Mouse model of erectile dysfunction due to diet-induced diabetes mellitus.

Xie D, Odronic SI, Wu F, Pippen A, Donatucci CF, Annex BH.

Urology. 2007 Jul;70(1):196-201.PMID: 17656247 [PubMed - indexed for MEDLINE]Related articlesFree article

A mouse model of hypercholesterolemia-induced erectile dysfunction.

Xie D, Odronic SI, Wu F, Pippen AM, Donatucci CF, Annex BH.

J Sex Med. 2007 Jul;4(4 Pt 1):898-907.PMID: 17627737 [PubMed - indexed for MEDLINE]Related articles

Engineered transcription factors for therapeutic angiogenesis.

Kontos CD, Annex BH.

Curr Opin Mol Ther. 2007 Apr;9(2):145-52. Review.PMID: 17458168 [PubMed - indexed for MEDLINE]Related articles

In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia.

Li Y, Hazarika S, Xie D, Pippen AM, Kontos CD, Annex BH.

Diabetes. 2007 Mar;56(3):656-65.PMID: 17327433 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice.

Li P, Waters RE, Redfern SI, Zhang M, Mao L, Annex BH, Yan Z.

Am J Pathol. 2007 Feb;170(2):599-608.PMID: 17255328 [PubMed - indexed for MEDLINE]Related articlesFree article

An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia.

Xie D, Li Y, Reed EA, Odronic SI, Kontos CD, Annex BH.

J Vasc Surg. 2006 Jul;44(1):166-75. Epub 2006 Jun 6.PMID: 16753278 [PubMed - indexed for MEDLINE]Related articles

Intracavernosal basic fibroblast growth factor improves vasoreactivity in the hypercholesterolemic rabbit.

Xie D, Pippen AM, Odronic SI, Annex BH, Donatucci CF.

J Sex Med. 2006 Mar;3(2):223-32.PMID: 16490015 [PubMed - indexed for MEDLINE]Related articles

Cholesterol feeding reduces vascular endothelial growth factor signaling in rabbit corporal tissues.

Xie D, Kontos CD, Donatucci CF, Annex BH.

J Sex Med. 2005 Sep;2(5):634-40. Erratum in: J Sex Med. 2005 Nov;2(6):876. PMID: 16422820 [PubMed - indexed for MEDLINE]Related articles

Angiogenic therapy for coronary artery and peripheral arterial disease.

Hughes GC, Annex BH.

Expert Rev Cardiovasc Ther. 2005 May;3(3):521-35. Review.PMID: 15889979 [PubMed - indexed for MEDLINE]Related articles

Decreases in corporeal vascular endothelial growth factor expression precede vasoreactivity changes in cholesterol fed rabbits.

Xie D, Thompson MA, Pippen AM, Waters RE, Donatucci CF, Annex BH.

J Urol. 2005 Apr;173(4):1418-22.PMID: 15758816 [PubMed - indexed for MEDLINE]Related articles

Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial.

Powell RJ, Dormandy J, Simons M, Morishita R, Annex BH.

Vasc Med. 2004 May;9(3):193-8.PMID: 15675184 [PubMed - indexed for MEDLINE]Related articles

Growth factor-induced therapeutic angiogenesis in the heart: protein therapy.

Annex BH, Simons M.

Cardiovasc Res. 2005 Feb 15;65(3):649-55. Review.PMID: 15664391 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia.

Huang J, Niu XL, Pippen AM, Annex BH, Kontos CD.

Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):354-8. Epub 2004 Nov 29.PMID: 15569824 [PubMed - indexed for MEDLINE]Related articlesFree article

Task force 3: Disclosure of relationships with commercial interests: policy for educational activities and publications.

Jacobs AK, Lindsay BD, Bellande BJ, Fonarow GC, Nishimura RA, Shah PM, Annex BH, Fuster V, Gibbons RJ, Jackson MJ, Rahimtoola SH.

J Am Coll Cardiol. 2004 Oct 19;44(8):1736-40. Review. No abstract available. PMID: 15489117 [PubMed - indexed for MEDLINE]Related articles

Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.

Dai Q, Huang J, Klitzman B, Dong C, Goldschmidt-Clermont PJ, March KL, Rokovich J, Johnstone B, Rebar EJ, Spratt SK, Case CC, Kontos CD, Annex BH.

Circulation. 2004 Oct 19;110(16):2467-75. Epub 2004 Oct 11.PMID: 15477407 [PubMed - indexed for MEDLINE]Related articlesFree article

Voluntary running induces fiber type-specific angiogenesis in mouse skeletal muscle.

Waters RE, Rotevatn S, Li P, Annex BH, Yan Z.

Am J Physiol Cell Physiol. 2004 Nov;287(5):C1342-8. Epub 2004 Jul 14.PMID: 15253894 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasticity of myocytes and capillaries: a possible coordinating role for VEGF.

Williams RS, Annex BH.

Circ Res. 2004 Jul 9;95(1):7-8. No abstract available. PMID: 15242980 [PubMed - indexed for MEDLINE]Related articlesFree article

Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial disease.

Rajagopalan S, Olin JW, Young S, Erikson M, Grossman PM, Mendelsohn FO, Regensteiner JG, Hiatt WR, Annex BH.

Hum Gene Ther. 2004 Jun;15(6):619-24.PMID: 15212720 [PubMed - indexed for MEDLINE]Related articles

Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology.

Faxon DP, Fuster V, Libby P, Beckman JA, Hiatt WR, Thompson RW, Topper JN, Annex BH, Rundback JH, Fabunmi RP, Robertson RM, Loscalzo J; American Heart Association.

Circulation. 2004 Jun 1;109(21):2617-25. Review. No abstract available. PMID: 15173044 [PubMed - indexed for MEDLINE]Related articlesFree article

Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization.

Hughes GC, Baklanov DV, Biswas SS, Pippen AM, DeGrado TR, Coleman RE, Landolfo CK, Lowe JE, Annex BH, Landolfo KP.

J Card Surg. 2004 Jan-Feb;19(1):21-7.PMID: 15108785 [PubMed - indexed for MEDLINE]Related articles

Preclinical models of human peripheral arterial occlusive disease: implications for investigation of therapeutic agents.

Waters RE, Terjung RL, Peters KG, Annex BH.

J Appl Physiol. 2004 Aug;97(2):773-80. Epub 2004 Apr 23. Review.PMID: 15107408 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic angiogenesis in chronically ischemic porcine myocardium: comparative effects of bFGF and VEGF.

Hughes GC, Biswas SS, Yin B, Coleman RE, DeGrado TR, Landolfo CK, Lowe JE, Annex BH, Landolfo KP.

Ann Thorac Surg. 2004 Mar;77(3):812-8.PMID: 14992878 [PubMed - indexed for MEDLINE]Related articles

Neovascularization in intimal hyperplasia is associated with vein graft failure after coronary artery bypass surgery.

Baklanov DV, Peters KG, Seidel AL, Taylor DA, Annex BH.

Vasc Med. 2003;8(3):163-7.PMID: 14989556 [PubMed - indexed for MEDLINE]Related articles

Intramyocardial and intracoronary basic fibroblast growth factor in porcine hibernating myocardium: a comparative study.

Biswas SS, Hughes GC, Scarborough JE, Domkowski PW, Diodato L, Smith ML, Landolfo C, Lowe JE, Annex BH, Landolfo KP.

J Thorac Cardiovasc Surg. 2004 Jan;127(1):34-43.PMID: 14752410 [PubMed - indexed for MEDLINE]Related articles

Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2).

Aviles RJ, Annex BH, Lederman RJ.

Br J Pharmacol. 2003 Oct;140(4):637-46.PMID: 14534147 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel protective effect of erythropoietin in the infarcted heart.

Parsa CJ, Matsumoto A, Kim J, Riel RU, Pascal LS, Walton GB, Thompson RB, Petrofski JA, Annex BH, Stamler JS, Koch WJ.

J Clin Invest. 2003 Oct;112(7):999-1007.PMID: 14523037 [PubMed - indexed for MEDLINE]Related articlesFree article

Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication.

Rajagopalan S, Mohler ER 3rd, Lederman RJ, Mendelsohn FO, Saucedo JF, Goldman CK, Blebea J, Macko J, Kessler PD, Rasmussen HS, Annex BH.

Circulation. 2003 Oct 21;108(16):1933-8. Epub 2003 Sep 22.PMID: 14504183 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular rarefaction in peripheral skeletal muscle after experimental heart failure.

Nusz DJ, White DC, Dai Q, Pippen AM, Thompson MA, Walton GB, Parsa CJ, Koch WJ, Annex BH.

Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1554-62.PMID: 12969880 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging, progenitor cell exhaustion, and atherosclerosis.

Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D, Ramaswami P, Pippen AM, Annex BH, Dong C, Taylor DA.

Circulation. 2003 Jul 29;108(4):457-63. Epub 2003 Jul 14.PMID: 12860902 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic basic fibroblast growth factor induces favorable histological changes in the corpus cavernosum of hypercholesterolemic rabbits.

Dai Q, Silverstein AD, Davies MG, Hagen PO, Donatucci CF, Annex BH.

J Urol. 2003 Aug;170(2 Pt 1):664-8.PMID: 12853852 [PubMed - indexed for MEDLINE]Related articles

Regional Angiogenesis with Vascular Endothelial Growth Factor (VEGF) in peripheral arterial disease: Design of the RAVE trial.

Rajagopalan S, Mohler E 3rd, Lederman RJ, Saucedo J, Mendelsohn FO, Olin J, Blebea J, Goldman C, Trachtenberg JD, Pressler M, Rasmussen H, Annex BH, Hirsch AT; Regional Angiogenesis With Vascular Endothelial Growth Factor trial.

Am Heart J. 2003 Jun;145(6):1114-8.PMID: 12796772 [PubMed - indexed for MEDLINE]Related articles