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The Deletion Variant of Nicotinamide Nucleotide Transhydrogenase (Nnt) Does Not Affect Insulin Secretion or Glucose Tolerance.

Wong N, Blair AR, Morahan G, Andrikopoulos S.

Endocrinology. 2009 Nov 11. [Epub ahead of print]PMID: 19906813 [PubMed - as supplied by publisher]Related articles

Obesity and Type 2 diabetes: Slow down!-Can metabolic deceleration protect the islet beta cell from excess nutrient-induced damage?

Andrikopoulos S.

Mol Cell Endocrinol. 2009 Oct 6. [Epub ahead of print]PMID: 19815054 [PubMed - as supplied by publisher]Related articles

Reactive oxygen species enhance insulin sensitivity.

Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, Bruce C, Shields BJ, Skiba B, Ooms LM, Stepto N, Wu B, Mitchell CA, Tonks NK, Watt MJ, Febbraio MA, Crack PJ, Andrikopoulos S, Tiganis T.

Cell Metab. 2009 Oct;10(4):260-72.PMID: 19808019 [PubMed - in process]Related articles

Position statement of the Australian Diabetes Society: individualisation of glycated haemoglobin targets for adults with diabetes mellitus.

Cheung NW, Conn JJ, d'Emden MC, Gunton JE, Jenkins AJ, Ross GP, Sinha AK, Andrikopoulos S, Colagiuri S, Twigg SM; Australian Diabetes Society.

Med J Aust. 2009 Sep 21;191(6):339-44.PMID: 19769558 [PubMed - indexed for MEDLINE]Related articles

Use of a temporary "solubilizing" peptide tag for the Fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation.

Hossain MA, Belgi A, Lin F, Zhang S, Shabanpoor F, Chan L, Belyea C, Truong HT, Blair AR, Andrikopoulos S, Tregear GW, Wade JD.

Bioconjug Chem. 2009 Jul;20(7):1390-6.PMID: 19552405 [PubMed - indexed for MEDLINE]Related articles

Laparoscopic transabdominal preperitoneal hernia repair (TAPP): stapling the mesh is not mandatory.

Kapiris S, Mavromatis T, Andrikopoulos S, Georgiades C, Floros D, Diamantopoulos G.

J Laparoendosc Adv Surg Tech A. 2009 Jun;19(3):419-22.PMID: 19397396 [PubMed - indexed for MEDLINE]Related articles

Evaluating the glucose tolerance test in mice.

Andrikopoulos S, Blair AR, Deluca N, Fam BC, Proietto J.

Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1323-32. Epub 2008 Sep 23.PMID: 18812462 [PubMed - indexed for MEDLINE]Related articles

Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver.

Visinoni S, Fam BC, Blair A, Rantzau C, Lamont BJ, Bouwman R, Watt MJ, Proietto J, Favaloro JM, Andrikopoulos S.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1132-41. Epub 2008 Sep 9.PMID: 18780768 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth.

Needham BE, Wlodek ME, Ciccotosto GD, Fam BC, Masters CL, Proietto J, Andrikopoulos S, Cappai R.

J Pathol. 2008 Jun;215(2):155-63.PMID: 18393365 [PubMed - indexed for MEDLINE]Related articles

Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function.

Kebede M, Favaloro J, Gunton JE, Laybutt DR, Shaw M, Wong N, Fam BC, Aston-Mourney K, Rantzau C, Zulli A, Proietto J, Andrikopoulos S.

Diabetes. 2008 Jul;57(7):1887-95. Epub 2008 Mar 28.PMID: 18375435 [PubMed - indexed for MEDLINE]Related articlesFree article

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin.

Aston-Mourney K, Proietto J, Morahan G, Andrikopoulos S.

Diabetologia. 2008 Apr;51(4):540-5. Epub 2008 Feb 2.PMID: 18246324 [PubMed - indexed for MEDLINE]Related articles

Modulation of central leptin sensitivity and energy balance in a rat model of diet-induced obesity.

Fam BC, Morris MJ, Hansen MJ, Kebede M, Andrikopoulos S, Proietto J, Thorburn AW.

Diabetes Obes Metab. 2007 Nov;9(6):840-52.PMID: 17924866 [PubMed - indexed for MEDLINE]Related articles

Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

Aston-Mourney K, Wong N, Kebede M, Zraika S, Balmer L, McMahon JM, Fam BC, Favaloro J, Proietto J, Morahan G, Andrikopoulos S.

Diabetologia. 2007 Dec;50(12):2476-85. Epub 2007 Oct 6.PMID: 17922105 [PubMed - indexed for MEDLINE]Related articles

Amylin in the periphery II: An updated mini-review.

Wookey PJ, Lutz TA, Andrikopoulos S.

ScientificWorldJournal. 2006 Dec 15;6:1642-55. Review.PMID: 17173182 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling.

Steinberg GR, Michell BJ, van Denderen BJ, Watt MJ, Carey AL, Fam BC, Andrikopoulos S, Proietto J, Görgün CZ, Carling D, Hotamisligil GS, Febbraio MA, Kay TW, Kemp BE.

Cell Metab. 2006 Dec;4(6):465-74.PMID: 17141630 [PubMed - indexed for MEDLINE]Related articles

Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice.

Steinberg GR, Watt MJ, Fam BC, Proietto J, Andrikopoulos S, Allen AM, Febbraio MA, Kemp BE.

Endocrinology. 2006 Aug;147(8):3906-14. Epub 2006 May 4.PMID: 16675525 [PubMed - indexed for MEDLINE]Related articlesFree article

The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets.

Zraika S, Aston-Mourney K, Laybutt DR, Kebede M, Dunlop ME, Proietto J, Andrikopoulos S.

Diabetologia. 2006 Jun;49(6):1254-63. Epub 2006 Mar 29.PMID: 16570159 [PubMed - indexed for MEDLINE]Related articles

Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis.

Lamont BJ, Visinoni S, Fam BC, Kebede M, Weinrich B, Papapostolou S, Massinet H, Proietto J, Favaloro J, Andrikopoulos S.

Endocrinology. 2006 Jun;147(6):2764-72. Epub 2006 Feb 23.PMID: 16497803 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet.

Andrikopoulos S, Massa CM, Aston-Mourney K, Funkat A, Fam BC, Hull RL, Kahn SE, Proietto J.

J Endocrinol. 2005 Oct;187(1):45-53.PMID: 16214940 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigational agents that protect pancreatic islet beta-cells from failure.

Aston-Mourney K, Proietto J, Andrikopoulos S.

Expert Opin Investig Drugs. 2005 Oct;14(10):1241-50. Review.PMID: 16185166 [PubMed - indexed for MEDLINE]Related articles

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.

Kooptiwut S, Kebede M, Zraika S, Visinoni S, Aston-Mourney K, Favaloro J, Tikellis C, Thomas MC, Forbes JM, Cooper ME, Dunlop M, Proietto J, Andrikopoulos S.

J Mol Endocrinol. 2005 Aug;35(1):39-48.PMID: 16087720 [PubMed - indexed for MEDLINE]Related articlesFree article

Socs1 deficiency enhances hepatic insulin signaling.

Jamieson E, Chong MM, Steinberg GR, Jovanovska V, Fam BC, Bullen DV, Chen Y, Kemp BE, Proietto J, Kay TW, Andrikopoulos S.

J Biol Chem. 2005 Sep 9;280(36):31516-21. Epub 2005 Jun 27.PMID: 15983045 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of increased glucose production: identifying potential therapeutic targets.

Proietto J, Andrikopoulos S.

J Investig Med. 2004 Sep;52(6):389-93. Review.PMID: 15612452 [PubMed - indexed for MEDLINE]Related articles

Metabolic adaptations of three inbred strains of mice (C57BL/6, DBA/2, and 129T2) in response to a high-fat diet.

Funkat A, Massa CM, Jovanovska V, Proietto J, Andrikopoulos S.

J Nutr. 2004 Dec;134(12):3264-9.PMID: 15570023 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated SNAP-25 is associated with fatty acid-induced impairment of mouse islet function.

Zraika S, Dunlop ME, Proietto J, Andrikopoulos S.

Biochem Biophys Res Commun. 2004 Apr 30;317(2):472-7.PMID: 15063781 [PubMed - indexed for MEDLINE]Related articles

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

Tikellis C, Wookey PJ, Candido R, Andrikopoulos S, Thomas MC, Cooper ME.

Diabetes. 2004 Apr;53(4):989-97.PMID: 15047614 [PubMed - indexed for MEDLINE]Related articlesFree article

Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy.

Kaczmarczyk SJ, Andrikopoulos S, Favaloro J, Domenighetti AA, Dunn A, Ernst M, Grail D, Fodero-Tavoletti M, Huggins CE, Delbridge LM, Zajac JD, Proietto J.

J Mol Endocrinol. 2003 Dec;31(3):449-59.PMID: 14664706 [PubMed - indexed for MEDLINE]Related articlesFree article

Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

Andrikopoulos S, Hull RL, Verchere CB, Wang F, Wilbur SM, Wight TN, Marzban L, Kahn SE.

Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E418-24. Epub 2003 Nov 12. Erratum in: Am J Physiol Endocrinol Metab. 2004 May;286(5):E862. PMID: 14613923 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney.

Lamont BJ, Andrikopoulos S, Funkat A, Favaloro J, Ye JM, Kraegen EW, Howlett KF, Zajac JD, Proietto J.

Diabetologia. 2003 Oct;46(10):1338-47. Epub 2003 Jul 29.PMID: 12898008 [PubMed - indexed for MEDLINE]Related articles

Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin.

Potter-Perigo S, Hull RL, Tsoi C, Braun KR, Andrikopoulos S, Teague J, Bruce Verchere C, Kahn SE, Wight TN.

Arch Biochem Biophys. 2003 May 15;413(2):182-90.PMID: 12729615 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle following insulin stimulation.

Carey AL, Lamont B, Andrikopoulos S, Koukoulas I, Proietto J, Febbraio MA.

Biochem Biophys Res Commun. 2003 Mar 21;302(4):837-40.PMID: 12646246 [PubMed - indexed for MEDLINE]Related articles

The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.

Vidal J, Verchere CB, Andrikopoulos S, Wang F, Hull RL, Cnop M, Olin KL, LeBoeuf RC, O'Brien KD, Chait A, Kahn SE.

Diabetologia. 2003 Jan;46(1):71-9. Epub 2003 Jan 9.PMID: 12637985 [PubMed - indexed for MEDLINE]Related articles

Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.

Hull RL, Andrikopoulos S, Verchere CB, Vidal J, Wang F, Cnop M, Prigeon RL, Kahn SE.

Diabetes. 2003 Feb;52(2):372-9.PMID: 12540610 [PubMed - indexed for MEDLINE]Related articlesFree article

The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets.

Zraika S, Dunlop M, Proietto J, Andrikopoulos S.

Arch Biochem Biophys. 2002 Sep 15;405(2):275-9.PMID: 12220542 [PubMed - indexed for MEDLINE]Related articles

Effects of free fatty acids on insulin secretion in obesity.

Zraika S, Dunlop M, Proietto J, Andrikopoulos S.

Obes Rev. 2002 May;3(2):103-12. Review.PMID: 12120417 [PubMed - indexed for MEDLINE]Related articles

Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure.

Kooptiwut S, Zraika S, Thorburn AW, Dunlop ME, Darwiche R, Kay TW, Proietto J, Andrikopoulos S.

Endocrinology. 2002 Jun;143(6):2085-92.PMID: 12021173 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.

Song S, Andrikopoulos S, Filippis C, Thorburn AW, Khan D, Proietto J.

Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E275-82.PMID: 11440903 [PubMed - indexed for MEDLINE]Related articlesFree article

Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.

Hull RL, Verchere CB, Andrikopoulos S, Wang F, Vidal J, Kahn SE.

Diabetes. 2001 Feb;50 Suppl 1:S184-5. No abstract available. PMID: 11272188 [PubMed - indexed for MEDLINE]Related articles

beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.

Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.

Diabetes. 2000 Dec;49(12):2056-62.PMID: 11118007 [PubMed - indexed for MEDLINE]Related articlesFree article

Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes.

Kahn SE, Andrikopoulos S, Verchere CB, Wang F, Hull RL, Vidal J.

Diabetologia. 2000 Oct;43(10):1309-12.PMID: 11079750 [PubMed - indexed for MEDLINE]Related articles

Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.

Andrikopoulos S, Verchere CB, Teague JC, Howell WM, Fujimoto WY, Wight TN, Kahn SE.

Diabetes. 1999 Oct;48(10):1962-70. Erratum in: Diabetes 2000 Jan;49(1):135. PMID: 10512360 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.

Kahn SE, Andrikopoulos S, Verchere CB.

Diabetes. 1999 Feb;48(2):241-53. Review.PMID: 10334297 [PubMed - indexed for MEDLINE]Related articlesFree article

Human aging is associated with parallel reductions in insulin and amylin release.

Dechenes CJ, Verchere CB, Andrikopoulos S, Kahn SE.

Am J Physiol. 1998 Nov;275(5 Pt 1):E785-91.PMID: 9814997 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans.

Kahn SE, Verchere CB, Andrikopoulos S, Asberry PJ, Leonetti DL, Wahl PW, Boyko EJ, Schwartz RS, Newell-Morris L, Fujimoto WY.

Diabetes. 1998 Apr;47(4):640-5.PMID: 9568698 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic overproduction of islet amyloid polypeptide (amylin) is not sufficient for islet amyloid formation.

Verchere CB, D'Alessio DA, Wang S, Andrikopoulos S, Kahn SE.

Horm Metab Res. 1997 Jun;29(6):311-6. Review.PMID: 9230354 [PubMed - indexed for MEDLINE]Related articles

Impaired regulation of hepatic fructose-1,6-biphosphatase in the New Zealand Obese mouse: an acquired defect.

Andrikopoulos S, Rosella G, Kaczmarczyk SJ, Zajac JD, Proietto J.

Metabolism. 1996 May;45(5):622-6.PMID: 8622607 [PubMed - indexed for MEDLINE]Related articles

The biochemical basis of increased hepatic glucose production in a mouse model of type 2 (non-insulin-dependent) diabetes mellitus.

Andrikopoulos S, Proietto J.

Diabetologia. 1995 Dec;38(12):1389-96.PMID: 8786011 [PubMed - indexed for MEDLINE]Related articles

Understanding the pathogenesis of type 2 diabetes: can we get off the metabolic merry-go-rounds?

Proietto J, Andrikopoulos S, Rosella G, Thorburn A.

Aust N Z J Med. 1995 Dec;25(6):870-5. Review.PMID: 8770366 [PubMed - indexed for MEDLINE]Related articles

Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin-responsive phosphoenolpyruvate carboxykinase gene.

Rosella G, Zajac JD, Baker L, Kaczmarczyk SJ, Andrikopoulos S, Adams TE, Proietto J.

Mol Endocrinol. 1995 Oct;9(10):1396-404.PMID: 8544847 [PubMed - indexed for MEDLINE]Related articles

Defects in liver and muscle glycogen metabolism in neonatal and adult New Zealand obese mice.

Thorburn A, Andrikopoulos S, Proietto J.

Metabolism. 1995 Oct;44(10):1298-302.PMID: 7476288 [PubMed - indexed for MEDLINE]Related articles