PubMed

Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma.

Willmon CL, Saloura V, Fridlender ZG, Wongthida P, Diaz RM, Thompson J, Kottke T, Federspiel M, Barber G, Albelda SM, Vile RG.

Cancer Res. 2009 Oct 1;69(19):7713-20. Epub 2009 Sep 22.PMID: 19773437 [PubMed - in process]Related articles

Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN.

Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM.

Cancer Cell. 2009 Sep 8;16(3):183-94.PMID: 19732719 [PubMed - indexed for MEDLINE]Related articles

Evaluation of an Attenuated Vesicular Stomatitis Virus (VSV) Vector expressing Interferon-beta for Use in Malignant Pleural Mesothelioma: Heterogeneity in Interferon-Responsiveness Defines Potential Efficacy.

Saloura V, Wang LC, Fridlender ZG, Sun J, Cheng G, Kapoor V, Sterman DH, Harty RN, Okumura A, Barber GN, Vile RG, Federspiel MJ, Russell S, Litzky L, Albelda SM.

Hum Gene Ther. 2009 Aug 28. [Epub ahead of print]PMID: 19715403 [PubMed - as supplied by publisher]Related articles

Targeted detoxification of selected reactive oxygen species in the vascular endothelium.

Shuvaev VV, Christofidou-Solomidou M, Bhora F, Laude K, Cai H, Dikalov S, Arguiri E, Solomides CC, Albelda SM, Harrison DG, Muzykantov VR.

J Pharmacol Exp Ther. 2009 Nov;331(2):404-11. Epub 2009 Aug 19.PMID: 19692634 [PubMed - in process]Related articles

The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer.

Crisanti MC, Wallace AF, Kapoor V, Vandermeers F, Dowling ML, Pereira LP, Coleman K, Campling BG, Fridlender ZG, Kao GD, Albelda SM.

Mol Cancer Ther. 2009 Aug;8(8):2221-31. Epub 2009 Aug 11.PMID: 19671764 [PubMed - in process]Related articles

Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.

Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR.

Am J Respir Crit Care Med. 2009 Aug 1;180(3):247-56. Epub 2009 Apr 2.PMID: 19342415 [PubMed - indexed for MEDLINE]Related articles

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

Carpenito C, Milone MC, Hassan R, Simonet JC, Lakhal M, Suhoski MM, Varela-Rohena A, Haines KM, Heitjan DF, Albelda SM, Carroll RG, Riley JL, Pastan I, June CH.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3360-5. Epub 2009 Feb 11.PMID: 19211796 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetics of soluble mesothelin in patients with malignant pleural mesothelioma during treatment.

Grigoriu BD, Chahine B, Vachani A, Gey T, Conti M, Sterman DH, Marchandise G, Porte H, Albelda SM, Scherpereel A.

Am J Respir Crit Care Med. 2009 May 15;179(10):950-4. Epub 2009 Feb 6.PMID: 19201924 [PubMed - indexed for MEDLINE]Related articles

Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy.

Kim S, Buchlis G, Fridlender ZG, Sun J, Kapoor V, Cheng G, Haas A, Cheung HK, Zhang X, Corbley M, Kaiser LR, Ling L, Albelda SM.

Cancer Res. 2008 Dec 15;68(24):10247-56.PMID: 19074893 [PubMed - indexed for MEDLINE]Related articles

Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma.

Christie JD, Ma SF, Aplenc R, Li M, Lanken PN, Shah CV, Fuchs B, Albelda SM, Flores C, Garcia JG.

Crit Care Med. 2008 Oct;36(10):2794-800.PMID: 18828194 [PubMed - indexed for MEDLINE]Related articles

Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells.

Carroll RG, Carpenito C, Shan X, Danet-Desnoyers G, Liu R, Jiang S, Albelda SM, Golovina T, Coukos G, Riley JL, Jonak ZL, June CH.

PLoS One. 2008 Sep 26;3(9):e3289.PMID: 18818761 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the MYLK gene is associated with development of acute lung injury after major trauma.

Christie JD, Ma SF, Aplenc R, Li M, Lanken PN, Shah CV, Fuchs B, Albelda SM, Flores C, Garcia JG.

Crit Care Med. 2008 Aug 28. [Epub ahead of print]PMID: 18766098 [PubMed - as supplied by publisher]Related articles

Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes.

Garnacho C, Albelda SM, Muzykantov VR, Muro S.

J Control Release. 2008 Sep 24;130(3):226-33. Epub 2008 Jun 18.PMID: 18606202 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers.

Wallace A, Kapoor V, Sun J, Mrass P, Weninger W, Heitjan DF, June C, Kaiser LR, Ling LE, Albelda SM.

Clin Cancer Res. 2008 Jun 15;14(12):3966-74.PMID: 18559619 [PubMed - indexed for MEDLINE]Related articlesFree article

B-cell depletion using an anti-CD20 antibody augments antitumor immune responses and immunotherapy in nonhematopoetic murine tumor models.

Kim S, Fridlender ZG, Dunn R, Kehry MR, Kapoor V, Blouin A, Kaiser LR, Albelda SM.

J Immunother. 2008 Jun;31(5):446-57.PMID: 18463540 [PubMed - indexed for MEDLINE]Related articles

Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature.

Ding BS, Hong N, Murciano JC, Ganguly K, Gottstein C, Christofidou-Solomidou M, Albelda SM, Fisher AB, Cines DB, Muzykantov VR.

Blood. 2008 Feb 15;111(4):1999-2006. Epub 2007 Nov 28.PMID: 18045968 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies.

Dziubla TD, Shuvaev VV, Hong NK, Hawkins BJ, Madesh M, Takano H, Simone E, Nakada MT, Fisher A, Albelda SM, Muzykantov VR.

Biomaterials. 2008 Jan;29(2):215-27. Epub 2007 Oct 24.PMID: 17950837 [PubMed - indexed for MEDLINE]Related articlesFree article

Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular superoxide.

Shuvaev VV, Tliba S, Nakada M, Albelda SM, Muzykantov VR.

J Pharmacol Exp Ther. 2007 Nov;323(2):450-7. Epub 2007 Aug 21.PMID: 17712041 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses.

Sterman DH, Recio A, Carroll RG, Gillespie CT, Haas A, Vachani A, Kapoor V, Sun J, Hodinka R, Brown JL, Corbley MJ, Parr M, Ho M, Pastan I, Machuzak M, Benedict W, Zhang XQ, Lord EM, Litzky LA, Heitjan DF, June CH, Kaiser LR, Vonderheide RH, Albelda SM, Kanther M.

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4456-66. Erratum in: Clin Cancer Res. 2007 Sep 1;13(17):5226. Kanther, Michelle [added]. PMID: 17671130 [PubMed - indexed for MEDLINE]Related articlesFree article

The vascular disrupting agent, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumor cytotoxic T lymphocytes.

Wallace A, LaRosa DF, Kapoor V, Sun J, Cheng G, Jassar A, Blouin A, Ching LM, Albelda SM.

Cancer Res. 2007 Jul 15;67(14):7011-9.PMID: 17638914 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response.

Sinha P, Clements VK, Bunt SK, Albelda SM, Ostrand-Rosenberg S.

J Immunol. 2007 Jul 15;179(2):977-83.PMID: 17617589 [PubMed - indexed for MEDLINE]Related articlesFree article

Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects.

Suzuki E, Sun J, Kapoor V, Jassar AS, Albelda SM.

Cancer Biol Ther. 2007 Jun;6(6):880-5. Epub 2007 Mar 1.PMID: 17582217 [PubMed - indexed for MEDLINE]Related articlesFree article

A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma.

Vachani A, Nebozhyn M, Singhal S, Alila L, Wakeam E, Muschel R, Powell CA, Gaffney P, Singh B, Brose MS, Litzky LA, Kucharczuk J, Kaiser LR, Marron JS, Showe MK, Albelda SM, Showe LC.

Clin Cancer Res. 2007 May 15;13(10):2905-15.PMID: 17504990 [PubMed - indexed for MEDLINE]Related articlesFree article

Eighth international mesothelioma interest group.

Carbone M, Albelda SM, Broaddus VC, Flores RM, Hillerdal G, Jaurand MC, Kjaerheim K, Pass HI, Robinson B, Tsao A.

Oncogene. 2007 Oct 25;26(49):6959-67. Epub 2007 May 14.PMID: 17496929 [PubMed - indexed for MEDLINE]Related articles

Cytokine gene therapy for malignant pleural mesothelioma.

Vachani A, Sterman DH, Albelda SM.

J Thorac Oncol. 2007 Apr;2(4):265-7. Review. No abstract available. PMID: 17409795 [PubMed - indexed for MEDLINE]Related articles

A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection.

Suzuki E, Kim S, Cheung HK, Corbley MJ, Zhang X, Sun L, Shan F, Singh J, Lee WC, Albelda SM, Ling LE.

Cancer Res. 2007 Mar 1;67(5):2351-9.PMID: 17332368 [PubMed - indexed for MEDLINE]Related articlesFree article

Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium.

Shuvaev VV, Christofidou-Solomidou M, Scherpereel A, Simone E, Arguiri E, Tliba S, Pick J, Kennel S, Albelda SM, Muzykantov VR.

J Control Release. 2007 Apr 2;118(2):235-44. Epub 2007 Jan 8.PMID: 17270308 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon beta adenoviral gene therapy in a patient with ovarian cancer.

Sterman DH, Gillespie CT, Carroll RG, Coughlin CM, Lord EM, Sun J, Haas A, Recio A, Kaiser LR, Coukos G, June CH, Albelda SM, Vonderheide RH.

Nat Clin Pract Oncol. 2006 Nov;3(11):633-9.PMID: 17080181 [PubMed - indexed for MEDLINE]Related articles

Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia.

Perkowski S, Scherpereel A, Murciano JC, Arguiri E, Solomides CC, Albelda SM, Muzykantov V, Christofidou-Solomidou M.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1050-8. Epub 2006 Jun 30.PMID: 16815892 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer.

Wilderman MJ, Kim S, Gillespie CT, Sun J, Kapoor V, Vachani A, Sterman DH, Kaiser LR, Albelda SM.

Mol Ther. 2006 May;13(5):910-7. Epub 2006 Feb 17.PMID: 16488193 [PubMed - indexed for MEDLINE]Related articles

Cycloxygenase-2 inhibition augments the efficacy of a cancer vaccine.

Haas AR, Sun J, Vachani A, Wallace AF, Silverberg M, Kapoor V, Albelda SM.

Clin Cancer Res. 2006 Jan 1;12(1):214-22.PMID: 16397045 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma.

Jassar AS, Suzuki E, Kapoor V, Sun J, Silverberg MB, Cheung L, Burdick MD, Strieter RM, Ching LM, Kaiser LR, Albelda SM.

Cancer Res. 2005 Dec 15;65(24):11752-61.PMID: 16357188 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy.

Sterman DH, Recio A, Vachani A, Sun J, Cheung L, DeLong P, Amin KM, Litzky LA, Wilson JM, Kaiser LR, Albelda SM.

Clin Cancer Res. 2005 Oct 15;11(20):7444-53.PMID: 16243818 [PubMed - indexed for MEDLINE]Related articlesFree article

Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity.

Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM.

Clin Cancer Res. 2005 Sep 15;11(18):6713-21.PMID: 16166452 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung.

Wilderman MJ, Sun J, Jassar AS, Kapoor V, Khan M, Vachani A, Suzuki E, Kinniry PA, Sterman DH, Kaiser LR, Albelda SM.

Cancer Res. 2005 Sep 15;65(18):8379-87.PMID: 16166316 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature.

Ding BS, Gottstein C, Grunow A, Kuo A, Ganguly K, Albelda SM, Cines DB, Muzykantov VR.

Blood. 2005 Dec 15;106(13):4191-8. Epub 2005 Sep 6.PMID: 16144802 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in the diagnosis, evaluation, and management of malignant pleural mesothelioma.

Sterman DH, Albelda SM.

Respirology. 2005 Jun;10(3):266-83. Review.PMID: 15955137 [PubMed - indexed for MEDLINE]Related articles

Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review.

Singhal S, Vachani A, Antin-Ozerkis D, Kaiser LR, Albelda SM.

Clin Cancer Res. 2005 Jun 1;11(11):3974-86. Review.PMID: 15930332 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma.

DeLong P, Carroll RG, Henry AC, Tanaka T, Ahmad S, Leibowitz MS, Sterman DH, June CH, Albelda SM, Vonderheide RH.

Cancer Biol Ther. 2005 Mar;4(3):342-6. Epub 2005 Mar 1.PMID: 15846066 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of lung cancer using clinically relevant oral doses of the cyclooxygenase-2 inhibitor rofecoxib: potential value as adjuvant therapy after surgery.

Tanaka T, Delong PA, Amin K, Henry A, Kruklitis R, Kapoor V, Kaiser LR, Albelda SM.

Ann Surg. 2005 Jan;241(1):168-78.PMID: 15622005 [PubMed - indexed for MEDLINE]Related articlesFree article

Soluble type II transforming growth factor-beta receptor inhibits established murine malignant mesothelioma tumor growth by augmenting host antitumor immunity.

Suzuki E, Kapoor V, Cheung HK, Ling LE, DeLong PA, Kaiser LR, Albelda SM.

Clin Cancer Res. 2004 Sep 1;10(17):5907-18.PMID: 15355924 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of lateral cell-cell border location and extracellular/transmembrane domains in PECAM/CD31 mechanosensation.

Kaufman DA, Albelda SM, Sun J, Davies PF.

Biochem Biophys Res Commun. 2004 Aug 6;320(4):1076-81.PMID: 15249199 [PubMed - indexed for MEDLINE]Related articles

Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcgamma receptor function.

Albelda SM, Lau KC, Chien P, Huang ZY, Arguiris E, Bohen A, Sun J, Billet JA, Christofidou-Solomidou M, Indik ZK, Schreiber AD.

Am J Respir Cell Mol Biol. 2004 Aug;31(2):246-55. Epub 2004 Apr 15.PMID: 15087304 [PubMed - indexed for MEDLINE]Related articlesFree article

Immuno-gene therapy with interferon-beta before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma.

Kruklitis RJ, Singhal S, Delong P, Kapoor V, Sterman DH, Kaiser LR, Albelda SM.

J Thorac Cardiovasc Surg. 2004 Jan;127(1):123-30.PMID: 14752422 [PubMed - indexed for MEDLINE]Related articles

TNFerade to the rescue? Guidelines for evaluating phase I cancer gene transfer trials.

Albelda SM, Sterman DH.

J Clin Oncol. 2004 Feb 15;22(4):577-9. Epub 2004 Jan 15. No abstract available. PMID: 14726507 [PubMed - indexed for MEDLINE]Related articles

Use of cyclooxygenase-2 inhibition to enhance the efficacy of immunotherapy.

DeLong P, Tanaka T, Kruklitis R, Henry AC, Kapoor V, Kaiser LR, Sterman DH, Albelda SM.

Cancer Res. 2003 Nov 15;63(22):7845-52.PMID: 14633712 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentially expressed apoptotic genes in early stage lung adenocarcinoma predicted by expression profiling.

Singhal S, Amin KM, Kruklitis R, Marshall MB, Kucharczuk JC, DeLong P, Litzky LA, Kaiser LR, Albelda SM.

Cancer Biol Ther. 2003 Sep-Oct;2(5):566-71.PMID: 14614329 [PubMed - indexed for MEDLINE]Related articlesFree article

Microarray data simulator for improved selection of differentially expressed genes.

Singhal S, Kyvernitis CG, Johnson SW, Kaiser LR, Liebman MN, Albelda SM.

Cancer Biol Ther. 2003 Jul-Aug;2(4):383-91.PMID: 14508110 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiling of malignant mesothelioma.

Singhal S, Wiewrodt R, Malden LD, Amin KM, Matzie K, Friedberg J, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM.

Clin Cancer Res. 2003 Aug 1;9(8):3080-97.PMID: 12912960 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in cell cycle genes in early stage lung adenocarcinoma identified by expression profiling.

Singhal S, Amin KM, Kruklitis R, DeLong P, Friscia ME, Litzky LA, Putt ME, Kaiser LR, Albelda SM.

Cancer Biol Ther. 2003 May-Jun;2(3):291-8.PMID: 12878869 [PubMed - indexed for MEDLINE]Related articlesFree article