PubMed

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.

Gao S, Alarcón C, Sapkota G, Rahman S, Chen PY, Goerner N, Macias MJ, Erdjument-Bromage H, Tempst P, Massagué J.

Mol Cell. 2009 Nov 13;36(3):457-68.PMID: 19917253 [PubMed - in process]Related articles

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.

Alarcón C, Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, Barlas A, Miller AN, Manova-Todorova K, Macias MJ, Sapkota G, Pan D, Massagué J.

Cell. 2009 Nov 13;139(4):757-69.PMID: 19914168 [PubMed - in process]Related articles

The "hijacking" of moral conscience from pharmacy practice: a canadian perspective.

Alarcon C.

Ann Pharmacother. 2009 Apr;43(4):748-53. Epub 2009 Mar 19.PMID: 19299535 [PubMed - in process]Related articles

Protein(s) from the Gram-Positive Bacterium Clavibacter michiganensis subsp. michiganensis Induces a Hypersensitive Response in Plants.

Alarcón C, Castro J, Muñoz F, Arce-Johnson P, Delgado J.

Phytopathology. 1998 Apr;88(4):306-10.PMID: 18944953 [PubMed - in process]Related articlesFree article

Endogenous human microRNAs that suppress breast cancer metastasis.

Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J.

Nature. 2008 Jan 10;451(7175):147-52.PMID: 18185580 [PubMed - indexed for MEDLINE]Related articlesFree article

The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead?

Uchizono Y, Alarcón C, Wicksteed BL, Marsh BJ, Rhodes CJ.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:56-66.PMID: 17919179 [PubMed - indexed for MEDLINE]Related articles

The distribution, density and three-dimensional histomorphology of Pacinian corpuscles in the foot of the Asian elephant (Elephas maximus) and their potential role in seismic communication.

Bouley DM, Alarcón CN, Hildebrandt T, O'Connell-Rodwell CE.

J Anat. 2007 Oct;211(4):428-35. Epub 2007 Aug 15.PMID: 17711421 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells.

Marsh BJ, Soden C, Alarcón C, Wicksteed BL, Yaekura K, Costin AJ, Morgan GP, Rhodes CJ.

Mol Endocrinol. 2007 Sep;21(9):2255-69. Epub 2007 Jun 19.PMID: 17579214 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.

Xing W, Singgih A, Kapoor A, Alarcon CM, Baylink DJ, Mohan S.

J Biol Chem. 2007 Jul 27;282(30):22052-61. Epub 2007 May 17.PMID: 17510056 [PubMed - indexed for MEDLINE]Related articlesFree article

A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.

Wicksteed B, Uchizono Y, Alarcon C, McCuaig JF, Shalev A, Rhodes CJ.

Cell Metab. 2007 Mar;5(3):221-7.PMID: 17339029 [PubMed - indexed for MEDLINE]Related articles

Balancing BMP signaling through integrated inputs into the Smad1 linker.

Sapkota G, Alarcón C, Spagnoli FM, Brivanlou AH, Massagué J.

Mol Cell. 2007 Feb 9;25(3):441-54.PMID: 17289590 [PubMed - indexed for MEDLINE]Related articles

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.

Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J.

J Biol Chem. 2006 Dec 29;281(52):40412-9. Epub 2006 Nov 2.PMID: 17085434 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.

Alarcon C, Wicksteed B, Rhodes CJ.

Diabetologia. 2006 Dec;49(12):2920-9. Epub 2006 Oct 20.PMID: 17053883 [PubMed - indexed for MEDLINE]Related articles

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.

Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alárcon C, Rhodes CJ, Newgard CB.

J Biol Chem. 2006 Nov 24;281(47):35624-32. Epub 2006 Sep 25.PMID: 17001083 [PubMed - indexed for MEDLINE]Related articlesFree article

C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells.

Gomis RR, Alarcón C, Nadal C, Van Poznak C, Massagué J.

Cancer Cell. 2006 Sep;10(3):203-14.PMID: 16959612 [PubMed - indexed for MEDLINE]Related articles

A FoxO-Smad synexpression group in human keratinocytes.

Gomis RR, Alarcón C, He W, Wang Q, Seoane J, Lash A, Massagué J.

Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12747-52. Epub 2006 Aug 14.PMID: 16908841 [PubMed - indexed for MEDLINE]Related articlesFree article

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.

Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11940-5. Epub 2006 Aug 1.PMID: 16882717 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells.

Lingohr MK, Briaud I, Dickson LM, McCuaig JF, Alárcon C, Wicksteed BL, Rhodes CJ.

J Biol Chem. 2006 Jun 9;281(23):15884-92. Epub 2006 Mar 30. Erratum in: J Biol Chem. 2006 Aug 11;281(32):23296. PMID: 16574657 [PubMed - indexed for MEDLINE]Related articlesFree article

Self-expanding metallic ureteral stents for treatment of ureteral stenosis after kidney transplantation.

Burgos FJ, Pascual J, Marcen R, García-Navas R, García IG, Alarcón C, Gómez V, García-Ortells D, Tabernero G, Ortuño J.

Transplant Proc. 2005 Nov;37(9):3828-9.PMID: 16386553 [PubMed - indexed for MEDLINE]Related articles

Arbuscular mycorrhizas in coastal sand dunes of the Paraguaná Peninsula, Venezuela.

Alarcón C, Cuenca G.

Mycorrhiza. 2005 Dec;16(1):1-9. Epub 2005 Nov 11.PMID: 16007471 [PubMed - indexed for MEDLINE]Related articles

Wisconsin and Celsior solutions in renal preservation: a comparative preliminary study.

Marcén R, Burgos FJ, Ocaña J, Pascual J, Perez-Sanz P, Galeano C, Teruel JL, López-Mateos M, Alarcón C, Ortuño J.

Transplant Proc. 2005 Apr;37(3):1419-20.PMID: 15866622 [PubMed - indexed for MEDLINE]Related articles

[Therapy with interferon plus ribavirin in hemodialysis patient with PCR-positive viral hepatitis C]

Arambarri M, Fernández Lucas M, Echarri R, Teruel JL, Alarcón C, Merino JL, Ortuño J.

Nefrologia. 2004;24 Suppl 3:39-42. Spanish. PMID: 15219067 [PubMed - indexed for MEDLINE]Related articles

Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule.

Sawchuk DJ, Mansilla-Soto J, Alarcon C, Singha NC, Langen H, Bianchi ME, Lees-Miller SP, Nussenzweig MC, Cortes P.

J Biol Chem. 2004 Jul 9;279(28):29821-31. Epub 2004 Apr 28.PMID: 15123719 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

[Ionic dialysance to control the dose of dialysis. One year experience]

Teruel JL, Fernández Lucas M, Arambarri M, Merino JL, Echarri R, Alarcón C, Marcén R, Rivera M, Ortuño J.

Nefrologia. 2003 Sep-Oct;23(5):444-50. Spanish. PMID: 14658171 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.

Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ.

J Biol Chem. 2003 Oct 24;278(43):42080-90. Epub 2003 Aug 18.PMID: 12928442 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

Xu L, Alarcón C, Cöl S, Massagué J.

J Biol Chem. 2003 Oct 24;278(43):42569-77. Epub 2003 Aug 13.PMID: 12917407 [PubMed - indexed for MEDLINE]Related articlesFree article

Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats.

Herrerías JM, Esteban JM, Caballero-Plasencia AM, Valenzuela-Barranco M, Motilva V, Alarcón C, Martín J, Herrerías JM Jr, Esteban P.

Dig Dis Sci. 2003 May;48(5):986-91.PMID: 12772800 [PubMed - indexed for MEDLINE]Related articles

Insulin secretory deficiency and glucose intolerance in Rab3A null mice.

Yaekura K, Julyan R, Wicksteed BL, Hays LB, Alarcon C, Sommers S, Poitout V, Baskin DG, Wang Y, Philipson LH, Rhodes CJ.

J Biol Chem. 2003 Mar 14;278(11):9715-21. Epub 2003 Jan 1.PMID: 12510060 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of earthworm (Eisenia fetida) and wheat (Triticum aestivum) straw additions on selected properties of petroleum-contaminated soils.

Callaham MA Jr, Stewart AJ, Alarcón C, McMillen SJ.

Environ Toxicol Chem. 2002 Aug;21(8):1658-63.PMID: 12152766 [PubMed - indexed for MEDLINE]Related articles

Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation.

Alarcon C, Wicksteed B, Prentki M, Corkey BE, Rhodes CJ.

Diabetes. 2002 Aug;51(8):2496-504.PMID: 12145163 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the bactericidal activity of the natural diterpene kaurenoic acid.

Wilkens M, Alarcón C, Urzúa A, Mendoza L.

Planta Med. 2002 May;68(5):452-4.PMID: 12058325 [PubMed - indexed for MEDLINE]Related articles

Mechanisms involved in protection afforded by L-arginine in ibuprofen-induced gastric damage: role of nitric oxide and prostaglandins.

Jiménez D, Martin MJ, Pozo D, Alarcón C, Esteban J, Bruseghini L, Esteras A, Motilva V.

Dig Dis Sci. 2002 Jan;47(1):44-53.PMID: 11837731 [PubMed - indexed for MEDLINE]Related articles

Use of epitope tags for routine analysis of transgene expression.

Alarcon CM, Umthun AR, Register JC 3rd.

Transgenic Res. 2001 Jun;10(3):183-92.PMID: 11437275 [PubMed - indexed for MEDLINE]Related articles

[Rheumatoid arthritis among mapuche aborigines. A 16 years experience in the IX Region of the Chile]

Kaliski S, Bustos L, Artigas C, Alarcón C, Vega MA, Cárdenas C.

Rev Med Chil. 2001 Mar;129(3):253-8. Spanish. PMID: 11372291 [PubMed - indexed for MEDLINE]Related articles

Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation.

Wicksteed B, Herbert TP, Alarcon C, Lingohr MK, Moss LG, Rhodes CJ.

J Biol Chem. 2001 Jun 22;276(25):22553-8. Epub 2001 Apr 10.PMID: 11297542 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast.

Alarcon CM, Heitman J, Cardenas ME.

Mol Biol Cell. 1999 Aug;10(8):2531-46.PMID: 10436010 [PubMed - indexed for MEDLINE]Related articlesFree article

Leaky transcription of variant surface glycoprotein gene expression sites in bloodstream african trypanosomes.

Alarcon CM, Pedram M, Donelson JE.

J Biol Chem. 1999 Jun 11;274(24):16884-93.PMID: 10358034 [PubMed - indexed for MEDLINE]Related articlesFree article

(Pro)insulin and insulin-like growth factor I complementary expression and roles in early development.

Alarcón C, Morales AV, Pimentel B, Serna J, de Pablo F.

Comp Biochem Physiol B Biochem Mol Biol. 1998 Sep;121(1):13-7. Review.PMID: 9972280 [PubMed - indexed for MEDLINE]Related articles

Insulin/insulin-like growth factor-I hybrid receptors with high affinity for insulin are developmentally regulated during neurogenesis.

García-de Lacoba M, Alarcón C, de la Rosa EJ, de Pablo F.

Endocrinology. 1999 Jan;140(1):233-43.PMID: 9886830 [PubMed - indexed for MEDLINE]Related articlesFree article

Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina.

Alarcón C, Serna J, Pérez-Villamil B, de Pablo F.

FEBS Lett. 1998 Oct 9;436(3):361-6.PMID: 9801149 [PubMed - indexed for MEDLINE]Related articles

Expression, enzyme activity, and subcellular localization of mammalian target of rapamycin in insulin-responsive cells.

Withers DJ, Ouwens DM, Nave BT, van der Zon GC, Alarcon CM, Cardenas ME, Heitman J, Maassen JA, Shepherd PR.

Biochem Biophys Res Commun. 1997 Dec 29;241(3):704-9.PMID: 9434772 [PubMed - indexed for MEDLINE]Related articles

FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae.

Alarcón CM, Heitman J.

Mol Cell Biol. 1997 Oct;17(10):5968-75.PMID: 9315655 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of prepancreatic (pro)insulin and the insulin receptor in prevention of embryonic apoptosis.

Morales AV, Serna J, Alarcón C, de la Rosa EJ, de Pablo F.

Endocrinology. 1997 Sep;138(9):3967-75.PMID: 9275088 [PubMed - indexed for MEDLINE]Related articlesFree article

Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast.

Alarcon CM, Cardenas ME, Heitman J.

Genes Dev. 1996 Feb 1;10(3):279-88.PMID: 8595879 [PubMed - indexed for MEDLINE]Related articlesFree article

Complementary roles of the insulin family of factors and receptors in early development and neurogenesis.

De Pablo F, Alarcón C, Díaz B, García-De Lacoba M, López-Carranza A, Morales AV, Pimentel B, Serna J, De la Rosa EJ.

Int J Dev Biol. 1996;Suppl 1:109S-110S. No abstract available. PMID: 9087719 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of short-term zinc supplementation on cellular immunity, respiratory symptoms, and growth of malnourished Equadorian children.

Sempértegui F, Estrella B, Correa E, Aguirre L, Saa B, Torres M, Navarrete F, Alarcón C, Carrión J, Rodríguez, Griffiths JK.

Eur J Clin Nutr. 1996 Jan;50(1):42-6.PMID: 8617190 [PubMed - indexed for MEDLINE]Related articles

Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina.

Hernández-Sánchez C, López-Carranza A, Alarcón C, de La Rosa EJ, de Pablo F.

Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9834-8.PMID: 7568228 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow necrosis.

Bermejo A, González FA, Villegas A, Alarcón C.

Am J Hematol. 1995 Sep;50(1):65-6. No abstract available. PMID: 7668231 [PubMed - indexed for MEDLINE]Related articles

cDNA expressed sequence tags of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite.

el-Sayed NM, Alarcon CM, Beck JC, Sheffield VC, Donelson JE.

Mol Biochem Parasitol. 1995 Jul;73(1-2):75-90.PMID: 8577350 [PubMed - indexed for MEDLINE]Related articles