PubMed

Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures.

Ainscow EK, Pilling JE, Brown NM, Orme AT, Sullivan M, Hargreaves AC, Cooke EL, Sullivan E, Carlsson S, Andersson TB.

Expert Opin Drug Saf. 2008 Jul;7(4):351-65.PMID: 18613800 [PubMed - indexed for MEDLINE]Related articles

Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.

Eto K, Yamashita T, Hirose K, Tsubamoto Y, Ainscow EK, Rutter GA, Kimura S, Noda M, Iino M, Kadowaki T.

Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E262-71. Epub 2003 Mar 18.PMID: 12644449 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels.

Ainscow EK, Mirshamsi S, Tang T, Ashford ML, Rutter GA.

J Physiol. 2002 Oct 15;544(Pt 2):429-45.PMID: 12381816 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of conventional kinesin in glucose-stimulated secretory granule movements and exocytosis in clonal pancreatic beta-cells.

Varadi A, Ainscow EK, Allan VJ, Rutter GA.

J Cell Sci. 2002 Nov 1;115(Pt 21):4177-89.PMID: 12356920 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells.

Pinton P, Tsuboi T, Ainscow EK, Pozzan T, Rizzuto R, Rutter GA.

J Biol Chem. 2002 Oct 4;277(40):37702-10. Epub 2002 Jul 30.PMID: 12149258 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms involved in secretory vesicle recruitment to the plasma membrane in beta-cells.

Varadi A, Ainscow EK, Allan VJ, Rutter GA.

Biochem Soc Trans. 2002 Apr;30(2):328-32.PMID: 12023874 [PubMed - indexed for MEDLINE]Related articles

Glucose-stimulated insulin secretion does not require activation of pyruvate dehydrogenase: impact of adenovirus-mediated overexpression of PDH kinase and PDH phosphate phosphatase in pancreatic islets.

Nicholls LI, Ainscow EK, Rutter GA.

Biochem Biophys Res Commun. 2002 Mar 8;291(4):1081-8.PMID: 11866475 [PubMed - indexed for MEDLINE]Related articles

Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism.

Ainscow EK, Rutter GA.

Diabetes. 2002 Feb;51 Suppl 1:S162-70.PMID: 11815476 [PubMed - indexed for MEDLINE]Related articlesFree article

Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.

Mitchell KJ, Pinton P, Varadi A, Tacchetti C, Ainscow EK, Pozzan T, Rizzuto R, Rutter GA.

J Cell Biol. 2001 Oct 1;155(1):41-51. Epub 2001 Sep 24.PMID: 11571310 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting of reporter molecules to mitochondria to measure calcium, ATP, and pH.

Porcelli AM, Pinton P, Ainscow EK, Chiesa A, Rugolo M, Rutter GA, Rizzuto R.

Methods Cell Biol. 2001;65:353-80. No abstract available. PMID: 11381603 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial priming modifies Ca2+ oscillations and insulin secretion in pancreatic islets.

Ainscow EK, Rutter GA.

Biochem J. 2001 Jan 15;353(Pt 2):175-80.PMID: 11139378 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA.

J Biol Chem. 2000 Nov 17;275(46):36269-77.PMID: 10967119 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.

Ainscow EK, Zhao C, Rutter GA.

Diabetes. 2000 Jul;49(7):1149-55.PMID: 10909972 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria.

Kavanagh NI, Ainscow EK, Brand MD.

Biochim Biophys Acta. 2000 Feb 24;1457(1-2):57-70.PMID: 10692550 [PubMed - indexed for MEDLINE]Related articles

Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.

Ainscow EK, Brand MD.

Eur J Biochem. 1999 Dec;266(3):737-49.PMID: 10583367 [PubMed - indexed for MEDLINE]Related articlesFree article

The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis.

Ainscow EK, Brand MD.

Eur J Biochem. 1999 Nov;265(3):1043-55.PMID: 10518800 [PubMed - indexed for MEDLINE]Related articlesFree article

Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.

Ainscow EK, Brand MD.

Eur J Biochem. 1999 Aug;263(3):671-85.PMID: 10469130 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

Kennedy HJ, Pouli AE, Ainscow EK, Jouaville LS, Rizzuto R, Rutter GA.

J Biol Chem. 1999 May 7;274(19):13281-91.PMID: 10224088 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantifying elasticity analysis: how external effectors cause changes to metabolic systems.

Ainscow EK, Brand MD.

Biosystems. 1999 Feb;49(2):151-9.PMID: 10203195 [PubMed - indexed for MEDLINE]Related articles

Control analysis of systems with reaction blocks that 'cross-talk'.

Ainscow EK, Brand MD.

Biochim Biophys Acta. 1998 Sep 7;1366(3):284-90.PMID: 9814842 [PubMed - indexed for MEDLINE]Related articles

Errors associated with metabolic control analysis. Application Of Monte-Carlo simulation of experimental data.

Ainscow EK, Brand MD.

J Theor Biol. 1998 Sep 21;194(2):223-33.PMID: 9778435 [PubMed - indexed for MEDLINE]Related articles

Top-down control analysis of systems with more than one common intermediate.

Ainscow EK, Brand MD.

Eur J Biochem. 1995 Aug 1;231(3):579-86.PMID: 7649156 [PubMed - indexed for MEDLINE]Related articlesFree article

The causes and functions of mitochondrial proton leak.

Brand MD, Chien LF, Ainscow EK, Rolfe DF, Porter RK.

Biochim Biophys Acta. 1994 Aug 30;1187(2):132-9. Review.PMID: 8075107 [PubMed - indexed for MEDLINE]Related articles