PubMed

Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.

Winzell MS, Wulff EM, Olsen GS, Sauerberg P, Gotfredsen CF, Ahrén B.

Eur J Pharmacol. 2009 Oct 8. [Epub ahead of print]PMID: 19818749 [PubMed - as supplied by publisher]Related articles

Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets.

Vikman J, Ahrén B.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:197-201.PMID: 19817802 [PubMed - in process]Related articles

beta-Cell research - A decade of rapid growth.

Ahrén B, Accili D, Boitard C, Efendic S, Henquin JC, Seino S, Steiner DF, Cerasi E.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:iv-ix. No abstract available. PMID: 19817782 [PubMed - in process]Related articles

Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events.

Ahrén B.

Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):487-98.PMID: 19748066 [PubMed - in process]Related articles

Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery.

Guldstrand M, Ahrén B, Näslund E, Holst JJ, Adamson U.

Diabetes Obes Metab. 2009 Nov;11(11):1027-33. Epub 2009 Jul 13.PMID: 19614945 [PubMed - in process]Related articles

Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.

Jönsson T, Granfeldt Y, Ahrén B, Branell UC, Pålsson G, Hansson A, Söderström M, Lindeberg S.

Cardiovasc Diabetol. 2009 Jul 16;8:35.PMID: 19604407 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men.

Lindgren O, Mari A, Deacon CF, Carr RD, Winzell MS, Vikman J, Ahrén B.

J Clin Endocrinol Metab. 2009 Aug;94(8):2887-92. Epub 2009 May 12.PMID: 19435824 [PubMed - indexed for MEDLINE]Related articles

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes.

Ahrén B.

Nat Rev Drug Discov. 2009 May;8(5):369-85. Epub 2009 Apr 14. Review. Erratum in: Nat Rev Drug Discov. 2009 Aug;8(8):626. Nat Rev Drug Discov. 2009 Jun;8(6):516. PMID: 19365392 [PubMed - indexed for MEDLINE]Related articles

Reappraisal of the intravenous glucose tolerance index for a simple assessment of insulin sensitivity in mice.

Pacini G, Ahrén M, Ahrén B.

Am J Physiol Regul Integr Comp Physiol. 2009 May;296(5):R1316-24. Epub 2009 Feb 11.PMID: 19211728 [PubMed - indexed for MEDLINE]Related articles

Altered glucose tolerance in women with deliberate self-harm.

Westling S, Ahrén B, Sunnqvist C, Träskman-Bendz L.

Psychoneuroendocrinology. 2009 Jul;34(6):878-83. Epub 2009 Feb 1.PMID: 19188027 [PubMed - indexed for MEDLINE]Related articles

Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes.

Ahrén B, Schweizer A, Dejager S, Dunning BE, Nilsson PM, Persson M, Foley JE.

J Clin Endocrinol Metab. 2009 Apr;94(4):1236-43. Epub 2009 Jan 27.PMID: 19174497 [PubMed - indexed for MEDLINE]Related articles

Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy.

Ferrannini E, Fonseca V, Zinman B, Matthews D, Ahrén B, Byiers S, Shao Q, Dejager S.

Diabetes Obes Metab. 2009 Feb;11(2):157-66.PMID: 19125777 [PubMed - indexed for MEDLINE]Related articles

Beta- and alpha-cell dysfunction in subjects developing impaired glucose tolerance: outcome of a 12-year prospective study in postmenopausal Caucasian women.

Ahrén B.

Diabetes. 2009 Mar;58(3):726-31. Epub 2008 Dec 18.PMID: 19095762 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of pituitary adenylate cyclase-activating polypeptide in the pancreatic endocrine system.

Ahrén B.

Ann N Y Acad Sci. 2008 Nov;1144:28-35. Review.PMID: 19076360 [PubMed - indexed for MEDLINE]Related articles

Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes.

Ahrén B.

Expert Opin Emerg Drugs. 2008 Dec;13(4):593-607. Review.PMID: 19046129 [PubMed - indexed for MEDLINE]Related articles

Arterial gastroduodenal infusion of cholecystokinin-33 stimulates the exocrine pancreatic enzyme release via an enteropancreatic reflex, without affecting the endocrine insulin secretion in pigs.

Rengman S, Weström B, Ahrén B, Pierzynowski SG.

Pancreas. 2009 Mar;38(2):213-8.PMID: 18852685 [PubMed - indexed for MEDLINE]Related articles

Sex-related differences in the associations between hyperleptinemia, insulin resistance and dysfibrinolysis.

Eriksson MA, Rask E, Johnson O, Carlström K, Ahrén B, Eliasson M, Boman K, Söderberg S.

Blood Coagul Fibrinolysis. 2008 Oct;19(7):625-32.PMID: 18832901 [PubMed - indexed for MEDLINE]Related articles

Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men.

Ahrén B, Mari A, Fyfe CL, Tsofliou F, Sneddon AA, Wahle KW, Winzell MS, Pacini G, Williams LM.

Eur J Clin Nutr. 2009 Jun;63(6):778-86. Epub 2008 Sep 3.PMID: 18772894 [PubMed - indexed for MEDLINE]Related articles

Disturbed alpha-cell function in mice with beta-cell specific overexpression of human islet amyloid polypeptide.

Ahrén B, Sörhede Winzell M.

Exp Diabetes Res. 2008;2008:304513.PMID: 18615201 [PubMed - indexed for MEDLINE]Related articlesFree article

Incretin and islet hormonal responses to fat and protein ingestion in healthy men.

Carr RD, Larsen MO, Winzell MS, Jelic K, Lindgren O, Deacon CF, Ahrén B.

Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E779-84. Epub 2008 Jul 8.PMID: 18612044 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin.

Ahrén B.

Vasc Health Risk Manag. 2008;4(2):383-94. Review.PMID: 18561513 [PubMed - indexed for MEDLINE]Related articlesFree article

Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.

Höppener JW, Jacobs HM, Wierup N, Sotthewes G, Sprong M, de Vos P, Berger R, Sundler F, Ahrén B.

Exp Diabetes Res. 2008;2008:697035.PMID: 18497871 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical measures of islet function: usefulness to characterize defects in diabetes.

Ahrén B, Pratley RE, Soubt M, Dunning BE, Foley JE.

Curr Diabetes Rev. 2008 May;4(2):129-45. Review.PMID: 18473760 [PubMed - indexed for MEDLINE]Related articles

Evidence that autonomic mechanisms contribute to the adaptive increase in insulin secretion during dexamethasone-induced insulin resistance in humans.

Ahrén B.

Diabetologia. 2008 Jun;51(6):1018-24. Epub 2008 Apr 24.PMID: 18437349 [PubMed - indexed for MEDLINE]Related articles

The islet enhancer vildagliptin: mechanisms of improved glucose metabolism.

Ahrén B, Foley JE.

Int J Clin Pract Suppl. 2008 Mar;(159):8-14. Review.PMID: 18269436 [PubMed - indexed for MEDLINE]Related articles

Reconstructing the pancreas: restoration of normoglycemia, exocrine function, and islet innervation by islet transplantation to the pancreas.

Stagner J, Ahren B, Sundler F, White K.

Transplant Proc. 2008 Mar;40(2):452-4.PMID: 18374098 [PubMed - indexed for MEDLINE]Related articles

The augmenting effect on insulin secretion by oral versus intravenous glucose is exaggerated by high-fat diet in mice.

Ahrén B, Winzell MS, Pacini G.

J Endocrinol. 2008 Apr;197(1):181-7.PMID: 18372244 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin.

Sneddon AA, Tsofliou F, Fyfe CL, Matheson I, Jackson DM, Horgan G, Winzell MS, Wahle KW, Ahren B, Williams LM.

Obesity (Silver Spring). 2008 May;16(5):1019-24. Epub 2008 Mar 6.PMID: 18356842 [PubMed - indexed for MEDLINE]Related articles

Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.

Winzell MS, Ahrén B.

J Mol Endocrinol. 2008 Feb;40(2):93-100.PMID: 18234911 [PubMed - indexed for MEDLINE]Related articlesFree article

[Two breakthroughs in the treatment of type 2 diabetes. Both the receptor agonist and enzyme inhibitors now available in the clinic]

Ahrén B.

Lakartidningen. 2007 Dec 5;104(49-50):3763-4. Swedish. No abstract available. PMID: 18214322 [PubMed - indexed for MEDLINE]Related articles

Body fat related to daily physical activity and insulin concentrations in non-diabetic children.

Dencker M, Thorsson O, Karlsson MK, Lindén C, Eiberg S, Wollmer P, Andersen LB, Ahrén B.

Clin Physiol Funct Imaging. 2008 Jul;28(4):211-5. Epub 2008 Jul 1.PMID: 18177416 [PubMed - indexed for MEDLINE]Related articles

GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors.

Ahrén B.

Curr Diab Rep. 2007 Oct;7(5):340-7. Review.PMID: 18173966 [PubMed - indexed for MEDLINE]Related articles

DPP-4 inhibitors.

Ahrén B.

Best Pract Res Clin Endocrinol Metab. 2007 Dec;21(4):517-33. Review.PMID: 18054733 [PubMed - indexed for MEDLINE]Related articles

Improved meal-related insulin processing contributes to the enhancement of B-cell function by the DPP-4 inhibitor vildagliptin in patients with type 2 diabetes.

Ahrén B, Pacini G, Tura A, Foley JE, Schweizer A.

Horm Metab Res. 2007 Nov;39(11):826-9.PMID: 17992639 [PubMed - indexed for MEDLINE]Related articles

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

Winzell MS, Ahrén B.

Pharmacol Ther. 2007 Dec;116(3):437-48. Epub 2007 Aug 29. Review.PMID: 17900700 [PubMed - indexed for MEDLINE]Related articles

A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease.

Lindeberg S, Jönsson T, Granfeldt Y, Borgstrand E, Soffman J, Sjöström K, Ahrén B.

Diabetologia. 2007 Sep;50(9):1795-807. Epub 2007 Jun 22.PMID: 17583796 [PubMed - indexed for MEDLINE]Related articles

Role of VIP and PACAP in islet function.

Winzell MS, Ahrén B.

Peptides. 2007 Sep;28(9):1805-13. Epub 2007 May 6. Review.PMID: 17559974 [PubMed - indexed for MEDLINE]Related articles

Improved metabolic risk markers following two 6-month physical activity programs among socioeconomic marginalized women of Native American ancestry in Lima, Peru.

Lindgärde F, Ahrén B.

Diabetes Care. 2007 Sep;30(9):2230-2. Epub 2007 May 31. No abstract available. PMID: 17540957 [PubMed - indexed for MEDLINE]Related articlesFree article

DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.

Ahrén B, Winzell MS, Wierup N, Sundler F, Burkey B, Hughes TE.

Regul Pept. 2007 Oct 4;143(1-3):97-103. Epub 2007 Apr 11.PMID: 17482289 [PubMed - indexed for MEDLINE]Related articles

Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet.

Winzell MS, Brand CL, Wierup N, Sidelmann UG, Sundler F, Nishimura E, Ahrén B.

Diabetologia. 2007 Jul;50(7):1453-62. Epub 2007 May 4.PMID: 17479245 [PubMed - indexed for MEDLINE]Related articles

Gender-specific links between hepatic 11beta reduction of cortisone and adipokines.

Mattsson C, Rask E, Carlström K, Andersson J, Eliasson M, Ahrén B, Söderberg S, Olsson T.

Obesity (Silver Spring). 2007 Apr;15(4):887-94.PMID: 17426324 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications.

Ahrén B.

Diabetes Care. 2007 Jun;30(6):1344-50. Epub 2007 Mar 2. Review. No abstract available. PMID: 17337494 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion and insulin sensitivity in relation to fasting glucose in healthy subjects.

Ahrén B.

Diabetes Care. 2007 Mar;30(3):644-8.PMID: 17327334 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 accelerates the onset of insulin action on glucose disappearance in mice.

Thomaseth K, Pavan A, Pacini G, Ahrén B.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1808-14. Epub 2007 Feb 20.PMID: 17311896 [PubMed - indexed for MEDLINE]Related articlesFree article

Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.

Gram DX, Ahrén B, Nagy I, Olsen UB, Brand CL, Sundler F, Tabanera R, Svendsen O, Carr RD, Santha P, Wierup N, Hansen AJ.

Eur J Neurosci. 2007 Jan;25(1):213-23.PMID: 17241282 [PubMed - indexed for MEDLINE]Related articles

The impact of large tidal volume ventilation on the absorption of inhaled insulin in rabbits.

Petersen AH, Laursen T, Ahrén B, Pieber TR, Clauson P, Wollmer P.

Eur J Pharm Sci. 2007 Mar;30(3-4):351-7. Epub 2006 Dec 15.PMID: 17239571 [PubMed - indexed for MEDLINE]Related articles

GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

Flodgren E, Olde B, Meidute-Abaraviciene S, Winzell MS, Ahrén B, Salehi A.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):240-5. Epub 2007 Jan 3.PMID: 17214971 [PubMed - indexed for MEDLINE]Related articles

Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.

Winzell MS, Magnusson C, Ahrén B.

Metabolism. 2007 Jan;56(1):122-8.PMID: 17161234 [PubMed - indexed for MEDLINE]Related articles

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.

Sørensen H, Winzell MS, Brand CL, Fosgerau K, Gelling RW, Nishimura E, Ahren B.

Diabetes. 2006 Dec;55(12):3463-9.PMID: 17130493 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum cholesteryl fatty acid composition and plasma glucose concentrations in Amerindian women.

Lindgärde F, Vessby B, Ahrén B.

Am J Clin Nutr. 2006 Nov;84(5):1009-13.PMID: 17093151 [PubMed - indexed for MEDLINE]Related articlesFree article