PubMed

Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization.

Skinner JR, Shew TM, Schwartz DM, Tzekov A, Lepus CM, Abumrad NA, Wolins NE.

J Biol Chem. 2009 Nov 6;284(45):30941-8. Epub 2009 Sep 11.PMID: 19748893 [PubMed - in process]Related articles

Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity.

Fabbrini E, Magkos F, Mohammed BS, Pietka T, Abumrad NA, Patterson BW, Okunade A, Klein S.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15430-5. Epub 2009 Aug 24.PMID: 19706383 [PubMed - in process]Related articles

Cellular fatty acid uptake: a pathway under construction.

Su X, Abumrad NA.

Trends Endocrinol Metab. 2009 Mar;20(2):72-7. Epub 2009 Jan 29. Review.PMID: 19185504 [PubMed - indexed for MEDLINE]Related articles

Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways.

Goldberg IJ, Eckel RH, Abumrad NA.

J Lipid Res. 2009 Apr;50 Suppl:S86-90. Epub 2008 Nov 24.PMID: 19033209 [PubMed - indexed for MEDLINE]Related articles

Genome-wide associations and metabolic disease: the big revolution.

Doria A, Abumrad NA.

Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):363-5. No abstract available. PMID: 18541992 [PubMed - indexed for MEDLINE]Related articles

Pharmacological activation of PPARbeta promotes rapid and calcineurin-dependent fiber remodeling and angiogenesis in mouse skeletal muscle.

Gaudel C, Schwartz C, Giordano C, Abumrad NA, Grimaldi PA.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E297-304. Epub 2008 May 20.PMID: 18492772 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on fatty acid uptake.

Smith J, Su X, El-Maghrabi R, Stahl PD, Abumrad NA.

J Biol Chem. 2008 May 16;283(20):13578-85. Epub 2008 Mar 18.PMID: 18353783 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice.

Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC.

J Biol Chem. 2008 May 9;283(19):13108-15. Epub 2008 Mar 10.PMID: 18332148 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress.

Nahlé Z, Hsieh M, Pietka T, Coburn CT, Grimaldi PA, Zhang MQ, Das D, Abumrad NA.

J Biol Chem. 2008 May 23;283(21):14317-26. Epub 2008 Feb 28.PMID: 18308721 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol.

Love-Gregory L, Sherva R, Sun L, Wasson J, Schappe T, Doria A, Rao DC, Hunt SC, Klein S, Neuman RJ, Permutt MA, Abumrad NA.

Hum Mol Genet. 2008 Jun 1;17(11):1695-704. Epub 2008 Feb 27.PMID: 18305138 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2008 Apr;57(4):846-59. Epub 2008 Jan 3.PMID: 18174526 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.

Mancuso DJ, Sims HF, Han X, Jenkins CM, Guan SP, Yang K, Moon SH, Pietka T, Abumrad NA, Schlesinger PH, Gross RW.

J Biol Chem. 2007 Nov 30;282(48):34611-22. Epub 2007 Oct 8.PMID: 17923475 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36 gene deletion reduces fat preference and intake but not post-oral fat conditioning in mice.

Sclafani A, Ackroff K, Abumrad NA.

Am J Physiol Regul Integr Comp Physiol. 2007 Nov;293(5):R1823-32. Epub 2007 Sep 5.PMID: 17804586 [PubMed - indexed for MEDLINE]Related articles

CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine.

Nassir F, Wilson B, Han X, Gross RW, Abumrad NA.

J Biol Chem. 2007 Jul 6;282(27):19493-501. Epub 2007 May 15.PMID: 17507371 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue.

Hajri T, Hall AM, Jensen DR, Pietka TA, Drover VA, Tao H, Eckel R, Abumrad NA.

Diabetes. 2007 Jul;56(7):1872-80. Epub 2007 Apr 17.PMID: 17440173 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine.

Nauli AM, Nassir F, Zheng S, Yang Q, Lo CM, Vonlehmden SB, Lee D, Jandacek RJ, Abumrad NA, Tso P.

Gastroenterology. 2006 Oct;131(4):1197-207. Epub 2006 Aug 16.PMID: 17030189 [PubMed - indexed for MEDLINE]Related articlesFree article

Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes.

Soccio T, Zhang YY, Bacci S, Mlynarski W, Placha G, Raggio G, Di Paola R, Marucci A, Johnstone MT, Gervino EV, Abumrad NA, Klein S, Trischitta V, Doria A.

Diabetes. 2006 Oct;55(10):2763-70.PMID: 17003341 [PubMed - indexed for MEDLINE]Related articlesFree article

The metabolism of cancer cells: moonlighting proteins and growth control.

Abumrad NA, Lange AJ.

Curr Opin Clin Nutr Metab Care. 2006 Jul;9(4):337-8. No abstract available. PMID: 16778560 [PubMed - indexed for MEDLINE]Related articles

CD36 may determine our desire for dietary fats.

Abumrad NA.

J Clin Invest. 2005 Nov;115(11):2965-7. Review.PMID: 16276408 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36 expression and brain function: does CD36 deficiency impact learning ability?

Abumrad NA, Ajmal M, Pothakos K, Robinson JK.

Prostaglandins Other Lipid Mediat. 2005 Sep;77(1-4):77-83. Epub 2004 Nov 26. Review.PMID: 16099393 [PubMed - indexed for MEDLINE]Related articles

CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood.

Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D, Tso P, Abumrad NA.

J Clin Invest. 2005 May;115(5):1290-7. Epub 2005 Apr 7.PMID: 15841205 [PubMed - indexed for MEDLINE]Related articlesFree article

FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms.

Bastie CC, Nahlé Z, McLoughlin T, Esser K, Zhang W, Unterman T, Abumrad NA.

J Biol Chem. 2005 Apr 8;280(14):14222-9. Epub 2005 Feb 3.PMID: 15691844 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

Noushmehr H, D'Amico E, Farilla L, Hui H, Wawrowsky KA, Mlynarski W, Doria A, Abumrad NA, Perfetti R.

Diabetes. 2005 Feb;54(2):472-81.PMID: 15677505 [PubMed - indexed for MEDLINE]Related articlesFree article

CD36-dependent fatty acid uptake regulates expression of peroxisome proliferator activated receptors.

Drover VA, Abumrad NA.

Biochem Soc Trans. 2005 Feb;33(Pt 1):311-5.PMID: 15667335 [PubMed - indexed for MEDLINE]Related articles

CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness.

Bastie CC, Hajri T, Drover VA, Grimaldi PA, Abumrad NA.

Diabetes. 2004 Sep;53(9):2209-16.PMID: 15331529 [PubMed - indexed for MEDLINE]Related articlesFree article

A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians.

Ma X, Bacci S, Mlynarski W, Gottardo L, Soccio T, Menzaghi C, Iori E, Lager RA, Shroff AR, Gervino EV, Nesto RW, Johnstone MT, Abumrad NA, Avogaro A, Trischitta V, Doria A.

Hum Mol Genet. 2004 Oct 1;13(19):2197-205. Epub 2004 Jul 28. Erratum in: Hum Mol Genet. 2005 Dec 15;14(24):3973. PMID: 15282206 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in plasma membrane properties and phosphatidylcholine subspecies of insect Sf9 cells due to expression of scavenger receptor class B, type I, and CD36.

Parathath S, Connelly MA, Rieger RA, Klein SM, Abumrad NA, De La Llera-Moya M, Iden CR, Rothblat GH, Williams DL.

J Biol Chem. 2004 Oct 1;279(40):41310-8. Epub 2004 Jul 27.PMID: 15280390 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-specific overexpression of CD36 reverses the insulin resistance and diabetes of MKR mice.

Héron-Milhavet L, Haluzik M, Yakar S, Gavrilova O, Pack S, Jou WC, Ibrahimi A, Kim H, Hunt D, Yau D, Asghar Z, Joseph J, Wheeler MB, Abumrad NA, LeRoith D.

Endocrinology. 2004 Oct;145(10):4667-76. Epub 2004 Jul 1.PMID: 15231693 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids.

Irie H, Krukenkamp IB, Brinkmann JF, Gaudette GR, Saltman AE, Jou W, Glatz JF, Abumrad NA, Ibrahimi A.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6819-24. Epub 2003 May 13.PMID: 12746501 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against the presence of an anandamide transporter.

Glaser ST, Abumrad NA, Fatade F, Kaczocha M, Studholme KM, Deutsch DG.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4269-74. Epub 2003 Mar 24.PMID: 12655057 [PubMed - indexed for MEDLINE]Related articlesFree article

Thyroid hormone transport by the rat fatty acid translocase.

van der Putten HH, Friesema EC, Abumrad NA, Everts ME, Visser TJ.

Endocrinology. 2003 Apr;144(4):1315-23.PMID: 12639914 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of overexpression and deficiency of fatty acid translocase (FAT)/CD36.

Febbraio M, Guy E, Coburn C, Knapp FF Jr, Beets AL, Abumrad NA, Silverstein RL.

Mol Cell Biochem. 2002 Oct;239(1-2):193-7. Review.PMID: 12479585 [PubMed - indexed for MEDLINE]Related articles

Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone.

Qi N, Kazdova L, Zidek V, Landa V, Kren V, Pershadsingh HA, Lezin ES, Abumrad NA, Pravenec M, Kurtz TW.

J Biol Chem. 2002 Dec 13;277(50):48501-7. Epub 2002 Oct 15.PMID: 12384507 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36.

Brinkmann JF, Abumrad NA, Ibrahimi A, van der Vusse GJ, Glatz JF.

Biochem J. 2002 Nov 1;367(Pt 3):561-70. Review.PMID: 12088505 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid transport across membranes: relevance to nutrition and metabolic pathology.

Hajri T, Abumrad NA.

Annu Rev Nutr. 2002;22:383-415. Epub 2002 Apr 4. Review.PMID: 12055351 [PubMed - indexed for MEDLINE]Related articles

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice.

Hajri T, Han XX, Bonen A, Abumrad NA.

J Clin Invest. 2002 May;109(10):1381-9.PMID: 12021254 [PubMed - indexed for MEDLINE]Related articlesFree article

DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis.

Buhman KK, Smith SJ, Stone SJ, Repa JJ, Wong JS, Knapp FF Jr, Burri BJ, Hamilton RL, Abumrad NA, Farese RV Jr.

J Biol Chem. 2002 Jul 12;277(28):25474-9. Epub 2002 Apr 16.PMID: 11959864 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of CD36 in membrane transport of long-chain fatty acids.

Ibrahimi A, Abumrad NA.

Curr Opin Clin Nutr Metab Care. 2002 Mar;5(2):139-45. Review.PMID: 11844979 [PubMed - indexed for MEDLINE]Related articles

The gene-nutrient-gene loop.

Abumrad NA.

Curr Opin Clin Nutr Metab Care. 2001 Sep;4(5):407-10.PMID: 11568502 [PubMed - indexed for MEDLINE]Related articles

Role of CD36 in membrane transport and utilization of long-chain fatty acids by different tissues.

Coburn CT, Hajri T, Ibrahimi A, Abumrad NA.

J Mol Neurosci. 2001 Apr-Jun;16(2-3):117-21; discussion 151-7. Review.PMID: 11478366 [PubMed - indexed for MEDLINE]Related articles

Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy.

Hajri T, Ibrahimi A, Coburn CT, Knapp FF Jr, Kurtz T, Pravenec M, Abumrad NA.

J Biol Chem. 2001 Jun 29;276(26):23661-6. Epub 2001 Apr 25.PMID: 11323420 [PubMed - indexed for MEDLINE]Related articlesFree article

Assay of membrane transport of long-chain fatty acids by adipocytes.

Abumrad NA.

Methods Mol Biol. 2001;155:147-55. Review. No abstract available. PMID: 11293067 [PubMed - indexed for MEDLINE]Related articles

Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats.

Pravenec M, Landa V, Zidek V, Musilova A, Kren V, Kazdova L, Aitman TJ, Glazier AM, Ibrahimi A, Abumrad NA, Qi N, Wang JM, St Lezin EM, Kurtz TW.

Nat Genet. 2001 Feb;27(2):156-8.PMID: 11175782 [PubMed - indexed for MEDLINE]Related articles

Lipid transporters: membrane transport systems for cholesterol and fatty acids.

Abumrad NA, Sfeir Z, Connelly MA, Coburn C.

Curr Opin Clin Nutr Metab Care. 2000 Jul;3(4):255-62. Review.PMID: 10929670 [PubMed - indexed for MEDLINE]Related articles

Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice.

Coburn CT, Knapp FF Jr, Febbraio M, Beets AL, Silverstein RL, Abumrad NA.

J Biol Chem. 2000 Oct 20;275(42):32523-9.PMID: 10913136 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin.

Ibrahimi A, Bonen A, Blinn WD, Hajri T, Li X, Zhong K, Cameron R, Abumrad NA.

J Biol Chem. 1999 Sep 17;274(38):26761-6.PMID: 10480880 [PubMed - indexed for MEDLINE]Related articlesFree article

A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

Febbraio M, Abumrad NA, Hajjar DP, Sharma K, Cheng W, Pearce SF, Silverstein RL.

J Biol Chem. 1999 Jul 2;274(27):19055-62.PMID: 10383407 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle contractile activity increases fatty acid metabolism and transport and FAT/CD36.

Bonen A, Dyck DJ, Ibrahimi A, Abumrad NA.

Am J Physiol. 1999 Apr;276(4 Pt 1):E642-9.PMID: 10198299 [PubMed - indexed for MEDLINE]Related articlesFree article

Two antiatherogenic effects of progesterone on human macrophages; inhibition of cholesteryl ester synthesis and block of its enhancement by glucocorticoids.

Cheng W, Lau OD, Abumrad NA.

J Clin Endocrinol Metab. 1999 Jan;84(1):265-71.PMID: 9920094 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.

Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J.

Nat Genet. 1999 Jan;21(1):76-83.PMID: 9916795 [PubMed - indexed for MEDLINE]Related articles