PubMed

Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?

Yazbeck R, Howarth GS, Abbott CA.

Trends Pharmacol Sci. 2009 Nov;30(11):600-7.PMID: 19837468 [PubMed - in process]Related articles

Dipeptidyl peptidase (DP) 6 and DP10: novel brain proteins implicated in human health and disease.

McNicholas K, Chen T, Abbott CA.

Clin Chem Lab Med. 2009;47(3):262-7. Review.PMID: 19676137 [PubMed - indexed for MEDLINE]Related articles

The in vivo expression of dipeptidyl peptidases 8 and 9.

Yu DM, Ajami K, Gall MG, Park J, Lee CS, Evans KA, McLaughlin EA, Pitman MR, Abbott CA, McCaughan GW, Gorrell MD.

J Histochem Cytochem. 2009 Nov;57(11):1025-40. Epub 2009 Jul 6.PMID: 19581630 [PubMed - indexed for MEDLINE]Related articlesFree article

Bioactivity of the Murex Homeopathic Remedy and of Extracts from an Australian Muricid Mollusc Against Human Cancer Cells.

Benkendorff K, McIver CM, Abbott CA.

Evid Based Complement Alternat Med. 2009 Jun 2. [Epub ahead of print]PMID: 19491143 [PubMed - as supplied by publisher]Related articlesFree article

Regulation of epithelial apical junctions and barrier function by Galpha13.

Donato R, Wood SA, Saunders I, Gundsambuu B, Yan Mak K, Abbott CA, Powell BC.

Biochim Biophys Acta. 2009 Jul;1793(7):1228-35. Epub 2009 May 3.PMID: 19406171 [PubMed - indexed for MEDLINE]Related articles

Effects of early mobilization on unhealed dysvascular transtibial amputation stumps: a clinical trial.

Vanross ER, Johnson S, Abbott CA.

Arch Phys Med Rehabil. 2009 Apr;90(4):610-7.PMID: 19345776 [PubMed - indexed for MEDLINE]Related articles

Growth factor based therapies and intestinal disease: is glucagon-like peptide-2 the new way forward?

Yazbeck R, Howarth GS, Abbott CA.

Cytokine Growth Factor Rev. 2009 Apr;20(2):175-84. Epub 2009 Mar 25. Review.PMID: 19324585 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidase 8 and 9--guilty by association?

Pitman MR, Sulda ML, Kuss B, Abbott CA.

Front Biosci. 2009 Jan 1;14:3619-33. Review.PMID: 19273298 [PubMed - indexed for MEDLINE]Related articles

Review: Dipeptidyl peptidase (DP) 6 and DP10: novel brain proteins implicated in human health and disease.

McNicholas K, Chen T, Abbott CA.

Clin Chem Lab Med. 2009 Jan 26. [Epub ahead of print]PMID: 19166374 [PubMed - as supplied by publisher]Related articles

11th Intelligent Systems for Molecular Biology 2003 (ISMB 2003).

Abbott CA.

Comp Funct Genomics. 2003;4(6):654-9.PMID: 18629025 [PubMed - in process]Related articlesFree article

Inhibiting dipeptidyl peptidase activity partially ameliorates colitis in mice.

Yazbeck R, Howarth GS, Geier MS, Demuth HU, Abbott CA.

Front Biosci. 2008 May 1;13:6850-8.PMID: 18508699 [PubMed - indexed for MEDLINE]Related articles

Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8.

Ajami K, Pitman MR, Wilson CH, Park J, Menz RI, Starr AE, Cox JH, Abbott CA, Overall CM, Gorrell MD.

FEBS Lett. 2008 Mar 5;582(5):819-25. Epub 2008 Feb 12. Erratum in: FEBS Lett. 2008 Apr 2;582(7):1168. PMID: 18275857 [PubMed - indexed for MEDLINE]Related articles

Effect of a focused and directed continuing education program on prehospital skill maintenance in key resuscitation areas.

De Lorenzo RA, Abbott CA.

J Emerg Med. 2007 Oct;33(3):293-7. Epub 2007 Jul 20.PMID: 17976562 [PubMed - indexed for MEDLINE]Related articles

Synergistic impacts of heat shock and spawning on the physiology and immune health of Crassostrea gigas: an explanation for summer mortality in Pacific oysters.

Li Y, Qin JG, Abbott CA, Li X, Benkendorff K.

Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2353-62. Epub 2007 Sep 26.PMID: 17898119 [PubMed - indexed for MEDLINE]Related articles

Adoption of a ventilator-associated pneumonia clinical practice guideline.

Abbott CA, Dremsa T, Stewart DW, Mark DD, Swift CC.

Worldviews Evid Based Nurs. 2006;3(4):139-52.PMID: 17177928 [PubMed - indexed for MEDLINE]Related articles

DPIV/CD26 and FAP in cancer: a tale of contradictions.

Sulda ML, Abbott CA, Hildebrandt M.

Adv Exp Med Biol. 2006;575:197-206. Review. No abstract available. PMID: 16700523 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidases and inflammatory bowel disease.

Abbott CA, Yazbeck R, Geier MS, Demuth HU, Howarth GS.

Adv Exp Med Biol. 2006;575:155-62. Review. No abstract available. PMID: 16700518 [PubMed - indexed for MEDLINE]Related articles

Prediction of dipeptidyl peptidase (DP) 8 structure by homology modelling.

Pitman MR, Menz RI, Abbott CA.

Adv Exp Med Biol. 2006;575:33-42. No abstract available. PMID: 16700506 [PubMed - indexed for MEDLINE]Related articles

Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.

Sanderson MP, Abbott CA, Tada H, Seno M, Dempsey PJ, Dunbar AJ.

J Cell Biochem. 2006 Oct 1;99(2):609-23.PMID: 16676357 [PubMed - indexed for MEDLINE]Related articles

Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity.

Chen T, Ajami K, McCaughan GW, Gai WP, Gorrell MD, Abbott CA.

Biochim Biophys Acta. 2006 Jan;1764(1):33-43. Epub 2005 Oct 28.PMID: 16290253 [PubMed - indexed for MEDLINE]Related articles

Foot ulcer risk is lower in South-Asian and african-Caribbean compared with European diabetic patients in the U.K.: the North-West diabetes foot care study.

Abbott CA, Garrow AP, Carrington AL, Morris J, Van Ross ER, Boulton AJ; North-West diabetes foot care study.

Diabetes Care. 2005 Aug;28(8):1869-75.PMID: 16043725 [PubMed - indexed for MEDLINE]Related articlesFree article

Development and resolution of experimental colitis in mice with targeted deletion of dipeptidyl peptidase IV.

Geier MS, Tenikoff D, Yazbeck R, McCaughan GW, Abbott CA, Howarth GS.

J Cell Physiol. 2005 Aug;204(2):687-92.PMID: 15754331 [PubMed - indexed for MEDLINE]Related articles

CD26.

Chen T, Smyth D, Abbott CA.

J Biol Regul Homeost Agents. 2004 Jan-Mar;18(1):47-54. No abstract available. PMID: 15323360 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity.

Ajami K, Abbott CA, McCaughan GW, Gorrell MD.

Biochim Biophys Acta. 2004 Jul 13;1679(1):18-28.PMID: 15245913 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of an adult-learning, self-directed model compared with traditional lecture-based teaching methods in out-of-hospital training.

De Lorenzo RA, Abbott CA.

Acad Emerg Med. 2004 Jan;11(1):33-7.PMID: 14709426 [PubMed - indexed for MEDLINE]Related articles

Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization.

Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW.

Hepatology. 2003 Sep;38(3):577-88.PMID: 12939584 [PubMed - indexed for MEDLINE]Related articles

Corneal confocal microscopy: a non-invasive surrogate of nerve fibre damage and repair in diabetic patients.

Malik RA, Kallinikos P, Abbott CA, van Schie CH, Morgan P, Efron N, Boulton AJ.

Diabetologia. 2003 May;46(5):683-8. Epub 2003 May 9.PMID: 12739016 [PubMed - indexed for MEDLINE]Related articles

Dipeptidyl peptidase IV gene family. The DPIV family.

Chen T, Ajami K, McCaughan GW, Gorrell MD, Abbott CA.

Adv Exp Med Biol. 2003;524:79-86.PMID: 12675227 [PubMed - indexed for MEDLINE]Related articles

Molecular chimeras and mutational analysis in the prolyl oligopeptidase gene family.

Ajami K, Abbott CA, Gysbers V, Kähne T, McCaughan GW, Gorrell MD.

Adv Exp Med Biol. 2003;524:49-55. No abstract available. PMID: 12675222 [PubMed - indexed for MEDLINE]Related articles

Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family.

Ajami K, Abbott CA, Obradovic M, Gysbers V, Kähne T, McCaughan GW, Gorrell MD.

Biochemistry. 2003 Jan 28;42(3):694-701.PMID: 12534281 [PubMed - indexed for MEDLINE]Related articles

Can motor nerve conduction velocity predict foot problems in diabetic subjects over a 6-year outcome period?

Carrington AL, Shaw JE, Van Schie CH, Abbott CA, Vileikyte L, Boulton AJ.

Diabetes Care. 2002 Nov;25(11):2010-5.PMID: 12401748 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison of the Neuropen against standard quantitative sensory-threshold measures for assessing peripheral nerve function.

Paisley AN, Abbott CA, van Schie CH, Boulton AJ.

Diabet Med. 2002 May;19(5):400-5.PMID: 12027928 [PubMed - indexed for MEDLINE]Related articles

The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort.

Abbott CA, Carrington AL, Ashe H, Bath S, Every LC, Griffiths J, Hann AW, Hussein A, Jackson N, Johnson KE, Ryder CH, Torkington R, Van Ross ER, Whalley AM, Widdows P, Williamson S, Boulton AJ; North-West Diabetes Foot Care Study.

Diabet Med. 2002 May;19(5):377-84.PMID: 12027925 [PubMed - indexed for MEDLINE]Related articles

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

Wang M, Gorrell MD, Abbott CA, Jaggi R, Marguet D, Dickinson RG.

J Gastroenterol Hepatol. 2002 Jan;17(1):66-71.PMID: 11895555 [PubMed - indexed for MEDLINE]Related articles

Risk of diabetes-related amputation in South Asians vs. Europeans in the UK.

Chaturvedi N, Abbott CA, Whalley A, Widdows P, Leggetter SY, Boulton AJ.

Diabet Med. 2002 Feb;19(2):99-104.PMID: 11874424 [PubMed - indexed for MEDLINE]Related articles

Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression.

Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW.

Am J Pathol. 2002 Feb;160(2):641-54.PMID: 11839585 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression.

Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW.

Gut. 2001 Oct;49(4):565-76.PMID: 11559656 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral vascular and nerve function associated with lower limb amputation in people with and without diabetes.

Carrington AL, Abbott CA, Griffiths J, Jackson N, Johnson SR, Kulkarni J, Van Ross ER, Boulton AJ.

Clin Sci (Lond). 2001 Sep;101(3):261-6.PMID: 11524043 [PubMed - indexed for MEDLINE]Related articles

A foot care program for diabetic unilateral lower-limb amputees.

Carrington AL, Abbott CA, Griffiths J, Jackson N, Johnson SR, Kulkarni J, Van Ross ER, Boulton AJ.

Diabetes Care. 2001 Feb;24(2):216-21.PMID: 11213868 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.

Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD.

Eur J Biochem. 2000 Oct;267(20):6140-50.PMID: 11012666 [PubMed - indexed for MEDLINE]Related articlesFree article

Post-proline-cleaving peptidases having DP IV like enzyme activity. Post-proline peptidases.

Abbott CA, Yu D, McCaughan GW, Gorrell MD.

Adv Exp Med Biol. 2000;477:103-9. Review.PMID: 10849735 [PubMed - indexed for MEDLINE]Related articles

Relating structure to function in the beta-propeller domain of dipeptidyl peptidase IV. Point mutations that influence adenosine deaminase binding, antibody binding and enzyme activity.

Gorrell MD, Abbott CA, Kähne T, Levy MT, Church WB, McCaughan GW.

Adv Exp Med Biol. 2000;477:89-95. Review.PMID: 10849733 [PubMed - indexed for MEDLINE]Related articles

Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance.

McCaughan GW, Gorrell MD, Bishop GA, Abbott CA, Shackel NA, McGuinness PH, Levy MT, Sharland AF, Bowen DG, Yu D, Slaitini L, Church WB, Napoli J.

Immunol Rev. 2000 Apr;174:172-91. Review.PMID: 10807516 [PubMed - indexed for MEDLINE]Related articles

Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted beta propeller domain.

Abbott CA, McCaughan GW, Levy MT, Church WB, Gorrell MD.

Eur J Biochem. 1999 Dec;266(3):798-810.PMID: 10583373 [PubMed - indexed for MEDLINE]Related articlesFree article

Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity.

Abbott CA, McCaughan GW, Gorrell MD.

FEBS Lett. 1999 Sep 24;458(3):278-84.PMID: 10570924 [PubMed - indexed for MEDLINE]Related articles

Laterality of lower limb amputation in diabetic patients. Study of 15 636 patients found no influence of laterality on risk of amputation.

Abbott CA, van Ross ER, Kulkarni J, Shaw JE, Carrington AL, Boulton AJ.

BMJ. 1999 Jul 31;319(7205):318-9. No abstract available. PMID: 10484642 [PubMed - indexed for MEDLINE]Related articles

Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis.

Levy MT, McCaughan GW, Abbott CA, Park JE, Cunningham AM, Müller E, Rettig WJ, Gorrell MD.

Hepatology. 1999 Jun;29(6):1768-78.PMID: 10347120 [PubMed - indexed for MEDLINE]Related articles

A comparative study of the Podotrack, a simple semiquantitative plantar pressure measuring device, and the optical pedobarograph in the assessment of pressures under the diabetic foot.

van Schie CH, Abbott CA, Vileikyte L, Shaw JE, Hollis S, Boulton AJ.

Diabet Med. 1999 Feb;16(2):154-9.PMID: 10229310 [PubMed - indexed for MEDLINE]Related articles

An analysis of dynamic forces transmitted through the foot in diabetic neuropathy.

Shaw JE, van Schie CH, Carrington AL, Abbott CA, Boulton AJ.

Diabetes Care. 1998 Nov;21(11):1955-9.PMID: 9802750 [PubMed - indexed for MEDLINE]Related articlesFree article

Multicenter study of the incidence of and predictive risk factors for diabetic neuropathic foot ulceration.

Abbott CA, Vileikyte L, Williamson S, Carrington AL, Boulton AJ.

Diabetes Care. 1998 Jul;21(7):1071-5.PMID: 9653597 [PubMed - indexed for MEDLINE]Related articlesFree article