PubMed

Interval training normalizes cardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy.

Stølen TO, Høydal MA, Kemi OJ, Catalucci D, Ceci M, Aasum E, Larsen T, Rolim N, Condorelli G, Smith GL, Wisløff U.

Circ Res. 2009 Sep 11;105(6):527-36. Epub 2009 Aug 13.PMID: 19679837 [PubMed - indexed for MEDLINE]Related articles

Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.

Krishnan J, Suter M, Windak R, Krebs T, Felley A, Montessuit C, Tokarska-Schlattner M, Aasum E, Bogdanova A, Perriard E, Perriard JC, Larsen T, Pedrazzini T, Krek W.

Cell Metab. 2009 Jun;9(6):512-24.PMID: 19490906 [PubMed - indexed for MEDLINE]Related articles

Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss.

Hafstad AD, Khalid AM, Hagve M, Lund T, Larsen TS, Severson DL, Clarke K, Berge RK, Aasum E.

Cardiovasc Res. 2009 Aug 1;83(3):519-26. Epub 2009 Apr 27.PMID: 19398469 [PubMed - indexed for MEDLINE]Related articles

Increased O2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice.

Boardman N, Hafstad AD, Larsen TS, Severson DL, Aasum E.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1373-9. Epub 2009 Mar 13.PMID: 19286944 [PubMed - indexed for MEDLINE]Related articles

Novel MRI method to detect altered left ventricular ejection and filling patterns in rodent models of disease.

Stuckey DJ, Carr CA, Tyler DJ, Aasum E, Clarke K.

Magn Reson Med. 2008 Sep;60(3):582-7.PMID: 18727095 [PubMed - indexed for MEDLINE]Related articles

Metabolic (in)flexibility of the diabetic heart.

Larsen TS, Aasum E.

Cardiovasc Drugs Ther. 2008 Apr;22(2):91-5. Review.PMID: 18247112 [PubMed - indexed for MEDLINE]Related articles

Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness.

Vinge LE, von Lueder TG, Aasum E, Qvigstad E, Gravning JA, How OJ, Edvardsen T, Bjørnerheim R, Ahmed MS, Mikkelsen BW, Oie E, Attramadal T, Skomedal T, Smiseth OA, Koch WJ, Larsen TS, Attramadal H.

J Biol Chem. 2008 Apr 18;283(16):10601-10. Epub 2007 Dec 29.PMID: 18165681 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice.

How OJ, Larsen TS, Hafstad AD, Khalid A, Myhre ES, Murray AJ, Boardman NT, Cole M, Clarke K, Severson DL, Aasum E.

Arch Physiol Biochem. 2007 Oct-Dec;113(4-5):211-20.PMID: 18158644 [PubMed - indexed for MEDLINE]Related articles

Myocardial mechanical dysfunction and calcium overload following rewarming from experimental hypothermia in vivo.

Kondratiev TV, Wold RM, Aasum E, Tveita T.

Cryobiology. 2008 Feb;56(1):15-21. Epub 2007 Oct 1.PMID: 17983615 [PubMed - indexed for MEDLINE]Related articles

Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice.

Aasum E, Khalid AM, Gudbrandsen OA, How OJ, Berge RK, Larsen TS.

J Mol Cell Cardiol. 2008 Jan;44(1):201-9. Epub 2007 Sep 7.PMID: 17931655 [PubMed - indexed for MEDLINE]Related articles

Work-independent assessment of efficiency in ex vivo working rodent hearts within the PVA-MVO2 framework.

How OJ, Aasum E, Larsen TS.

Acta Physiol (Oxf). 2007 Jun;190(2):171-5. Epub 2007 Mar 30. No abstract available. PMID: 17394570 [PubMed - indexed for MEDLINE]Related articles

Glucose and insulin improve cardiac efficiency and postischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice.

Hafstad AD, Khalid AM, How OJ, Larsen TS, Aasum E.

Am J Physiol Endocrinol Metab. 2007 May;292(5):E1288-94. Epub 2007 Jan 9.PMID: 17213470 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway.

Pellieux C, Aasum E, Larsen TS, Montessuit C, Papageorgiou I, Pedrazzini T, Lerch R.

J Mol Cell Cardiol. 2006 Sep;41(3):459-66. Epub 2006 Jul 21.PMID: 16859699 [PubMed - indexed for MEDLINE]Related articles

Reduced coronary reserve in response to short-term ischaemia and vasoactive drugs in ex vivo hearts from diabetic mice.

Bratkovsky SV, Aasum E, Riemersma RA, Myhre ES, Larsen TS.

Acta Physiol (Oxf). 2006 Mar;186(3):171-7.PMID: 16497196 [PubMed - indexed for MEDLINE]Related articles

Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice.

How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS.

Diabetes. 2006 Feb;55(2):466-73.PMID: 16443782 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes.

Oakes ND, Thalén P, Aasum E, Edgley A, Larsen T, Furler SM, Ljung B, Severson D.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E870-81. Epub 2005 Dec 13.PMID: 16352676 [PubMed - indexed for MEDLINE]Related articlesFree article

Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin.

Hafstad AD, Solevåg GH, Severson DL, Larsen TS, Aasum E.

Am J Physiol Heart Circ Physiol. 2006 May;290(5):H1763-9. Epub 2005 Dec 3.PMID: 16327015 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice.

Aasum E, Cooper M, Severson DL, Larsen TS.

Can J Physiol Pharmacol. 2005 Feb;83(2):183-90.PMID: 15791292 [PubMed - indexed for MEDLINE]Related articles

Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts.

How OJ, Aasum E, Kunnathu S, Severson DL, Myhre ES, Larsen TS.

Am J Physiol Heart Circ Physiol. 2005 Jun;288(6):H2979-85. Epub 2005 Mar 11.PMID: 15764683 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous glycogen prevents Ca2+ overload and hypercontracture in harp seal myocardial cells during simulated ischemia.

Henden T, Aasum E, Folkow L, Mjøs OD, Lathrop DA, Larsen TS.

J Mol Cell Cardiol. 2004 Jul;37(1):43-50.PMID: 15242734 [PubMed - indexed for MEDLINE]Related articles

Measurement of coronary flow reserve in isolated hearts from mice.

Bratkovsky S, Aasum E, Birkeland CH, Riemersma RA, Myhre ES, Larsen TS.

Acta Physiol Scand. 2004 Jun;181(2):167-72.PMID: 15180788 [PubMed - indexed for MEDLINE]Related articles

Treatment of type 2 diabetic db/db mice with a novel PPARgamma agonist improves cardiac metabolism but not contractile function.

Carley AN, Semeniuk LM, Shimoni Y, Aasum E, Larsen TS, Berger JP, Severson DL.

Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E449-55. Epub 2003 Nov 4.PMID: 14600074 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in substrate metabolism in isolated mouse hearts following ischemia-reperfusion.

Aasum E, Hafstad AD, Larsen TS.

Mol Cell Biochem. 2003 Jul;249(1-2):97-103.PMID: 12956404 [PubMed - indexed for MEDLINE]Related articles

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice.

Aasum E, Hafstad AD, Severson DL, Larsen TS.

Diabetes. 2003 Feb;52(2):434-41.PMID: 12540618 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator.

Aasum E, Belke DD, Severson DL, Riemersma RA, Cooper M, Andreassen M, Larsen TS.

Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H949-57.PMID: 12181123 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-insulin-potassium reduces infarct size when administered during reperfusion.

Jonassen AK, Aasum E, Riemersma RA, Mjøs OD, Larsen TS.

Cardiovasc Drugs Ther. 2000 Dec;14(6):615-23.PMID: 11300362 [PubMed - indexed for MEDLINE]Related articles

Different tolerance to hypothermia and rewarming of isolated rat and guinea pig hearts.

Aasum E, Larsen TS.

Cryobiology. 1999 May;38(3):243-9.PMID: 10328914 [PubMed - indexed for MEDLINE]Related articles

The role of glycolysis in myocardial calcium control.

Aasum E, Lathrop DA, Henden T, Sundset R, Larsen TS.

J Mol Cell Cardiol. 1998 Sep;30(9):1703-12.PMID: 9769226 [PubMed - indexed for MEDLINE]Related articles

Stimulation of carbohydrate metabolism reduces hypothermia-induced calcium load in fatty acid-perfused rat hearts.

Aasum E, Steigen TK, Larsen TS.

J Mol Cell Cardiol. 1997 Feb;29(2):527-34.PMID: 9140812 [PubMed - indexed for MEDLINE]Related articles

Pyruvate reverses fatty-acid-induced depression of ventricular function and calcium overload after hypothermia in guinea pig hearts.

Aasum E, Larsen TS.

Cardiovasc Res. 1997 Feb;33(2):370-7.PMID: 9074701 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of fatty acids on myocardial calcium control during hypothermic perfusion.

Steigen TK, Aasum E, Myrmel T, Larsen TS.

J Thorac Cardiovasc Surg. 1994 Jan;107(1):233-41.PMID: 8283891 [PubMed - indexed for MEDLINE]Related articles