PubMed

Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis.

Zaitsev S, Spitzer D, Murciano JC, Ding BS, Tliba S, Kowalska MA, Bdeir K, Kuo A, Stepanova V, Atkinson JP, Poncz M, Cines DB, Muzykantov VR.

J Pharmacol Exp Ther. 2009 Dec 1. [Epub ahead of print]PMID: 19952305 [PubMed - as supplied by publisher]Related articlesFree article

Properdin: Emerging Roles of a Pattern-Recognition Molecule.

Kemper C, Atkinson JP, Hourcade DE.

Annu Rev Immunol. 2009 Nov 30. [Epub ahead of print]PMID: 19947883 [PubMed - as supplied by publisher]Related articles

CD46-induced human Treg enhance B-cell responses.

Fuchs A, Atkinson JP, Fremeaux-Bacchi V, Kemper C.

Eur J Immunol. 2009 Sep 25;39(11):3097-3109. [Epub ahead of print]PMID: 19784949 [PubMed - as supplied by publisher]Related articles

Smallpox inhibitor of complement enzymes (SPICE): dissecting functional sites and abrogating activity.

Liszewski MK, Leung MK, Hauhart R, Fang CJ, Bertram P, Atkinson JP.

J Immunol. 2009 Sep 1;183(5):3150-9. Epub 2009 Aug 10.PMID: 19667083 [PubMed - indexed for MEDLINE]Related articles

Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.

Reynolds R, Hartnett ME, Atkinson JP, Giclas PC, Rosner B, Seddon JM.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5818-27. Epub 2009 Aug 6.PMID: 19661236 [PubMed - in process]Related articles

Inhibiting complement activation on cells at the step of C3 cleavage.

Liszewski MK, Fang CJ, Atkinson JP.

Vaccine. 2008 Dec 30;26 Suppl 8:I22-7. Review.PMID: 19388160 [PubMed - indexed for MEDLINE]Related articles

Complement-dependent neutrophil recruitment is critical for the development of elastase-induced abdominal aortic aneurysm.

Pagano MB, Zhou HF, Ennis TL, Wu X, Lambris JD, Atkinson JP, Thompson RW, Hourcade DE, Pham CT.

Circulation. 2009 Apr 7;119(13):1805-13. Epub 2009 Mar 23.PMID: 19307471 [PubMed - indexed for MEDLINE]Related articles

Measles virus and CD46.

Kemper C, Atkinson JP.

Curr Top Microbiol Immunol. 2009;329:31-57. Review.PMID: 19198561 [PubMed - indexed for MEDLINE]Related articles

Surviving mousepox infection requires the complement system.

Moulton EA, Atkinson JP, Buller RM.

PLoS Pathog. 2008 Dec;4(12):e1000249. Epub 2008 Dec 26.PMID: 19112490 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic IL-17 responses in human and murine primary biliary cirrhosis.

Lan RY, Salunga TL, Tsuneyama K, Lian ZX, Yang GX, Hsu W, Moritoki Y, Ansari AA, Kemper C, Price J, Atkinson JP, Coppel RL, Gershwin ME.

J Autoimmun. 2009 Feb;32(1):43-51. Epub 2008 Dec 19.PMID: 19101114 [PubMed - indexed for MEDLINE]Related articles

Images in clinical medicine. New-onset clubbing associated with lung cancer.

Faller BA, Atkinson JP.

N Engl J Med. 2008 Sep 25;359(13):e15. No abstract available. PMID: 18815393 [PubMed - indexed for MEDLINE]Related articles

Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome.

Frémeaux-Bacchi V, Miller EC, Liszewski MK, Strain L, Blouin J, Brown AL, Moghal N, Kaplan BS, Weiss RA, Lhotta K, Kapur G, Mattoo T, Nivet H, Wong W, Gie S, Hurault de Ligny B, Fischbach M, Gupta R, Hauhart R, Meunier V, Loirat C, Dragon-Durey MA, Fridman WH, Janssen BJ, Goodship TH, Atkinson JP.

Blood. 2008 Dec 15;112(13):4948-52. Epub 2008 Sep 16.PMID: 18796626 [PubMed - indexed for MEDLINE]Related articles

Smallpox inhibitor of complement enzymes (SPICE): regulation of complement activation on cells and mechanism of its cellular attachment.

Liszewski MK, Bertram P, Leung MK, Hauhart R, Zhang L, Atkinson JP.

J Immunol. 2008 Sep 15;181(6):4199-207.PMID: 18768877 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in understanding of pathogenesis of aHUS and HELLP.

Fang CJ, Richards A, Liszewski MK, Kavanagh D, Atkinson JP.

Br J Haematol. 2008 Nov;143(3):336-48. Epub 2008 Aug 4. Review.PMID: 18691170 [PubMed - indexed for MEDLINE]Related articles

Membrane protein Crry maintains homeostasis of the complement system.

Wu X, Spitzer D, Mao D, Peng SL, Molina H, Atkinson JP.

J Immunol. 2008 Aug 15;181(4):2732-40.PMID: 18684964 [PubMed - indexed for MEDLINE]Related articlesFree article

New roles for the major human 3'-5' exonuclease TREX1 in human disease.

Kavanagh D, Spitzer D, Kothari PH, Shaikh A, Liszewski MK, Richards A, Atkinson JP.

Cell Cycle. 2008 Jun 15;7(12):1718-25. Epub 2008 Jun 16. Review.PMID: 18583934 [PubMed - indexed for MEDLINE]Related articles

Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E.

Avirutnan P, Zhang L, Punyadee N, Manuyakorn A, Puttikhunt C, Kasinrerk W, Malasit P, Atkinson JP, Diamond MS.

PLoS Pathog. 2007 Nov;3(11):e183.PMID: 18052531 [PubMed - indexed for MEDLINE]Related articlesFree article

Inherited complement regulatory protein deficiency predisposes to human disease in acute injury and chronic inflammatory statesthe examples of vascular damage in atypical hemolytic uremic syndrome and debris accumulation in age-related macular degeneration.

Richards A, Kavanagh D, Atkinson JP.

Adv Immunol. 2007;96:141-77. Review.PMID: 17981206 [PubMed - indexed for MEDLINE]Related articles

Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome.

Fang CJ, Fremeaux-Bacchi V, Liszewski MK, Pianetti G, Noris M, Goodship TH, Atkinson JP.

Blood. 2008 Jan 15;111(2):624-32. Epub 2007 Oct 3.PMID: 17914026 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic humoral autoimmunity but joint-specific inflammation: the syndrome of rheumatoid arthritis.

Wu X, Shih F, Atkinson JP.

Arthritis Rheum. 2007 Sep;56(9):2823-8. No abstract available. PMID: 17763409 [PubMed - indexed for MEDLINE]Related articlesFree article

Screening for complement system abnormalities in patients with atypical hemolytic uremic syndrome.

Kavanagh D, Richards A, Fremeaux-Bacchi V, Noris M, Goodship T, Remuzzi G, Atkinson JP.

Clin J Am Soc Nephrol. 2007 May;2(3):591-6. Epub 2007 Feb 14. Review. No abstract available. PMID: 17699467 [PubMed - indexed for MEDLINE]Related articlesFree article

Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly.

Spitzer D, Mitchell LM, Atkinson JP, Hourcade DE.

J Immunol. 2007 Aug 15;179(4):2600-8.PMID: 17675523 [PubMed - indexed for MEDLINE]Related articlesFree article

C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy.

Richards A, van den Maagdenberg AM, Jen JC, Kavanagh D, Bertram P, Spitzer D, Liszewski MK, Barilla-Labarca ML, Terwindt GM, Kasai Y, McLellan M, Grand MG, Vanmolkot KR, de Vries B, Wan J, Kane MJ, Mamsa H, Schäfer R, Stam AH, Haan J, de Jong PT, Storimans CW, van Schooneveld MJ, Oosterhuis JA, Gschwendter A, Dichgans M, Kotschet KE, Hodgkinson S, Hardy TA, Delatycki MB, Hajj-Ali RA, Kothari PH, Nelson SF, Frants RR, Baloh RW, Ferrari MD, Atkinson JP.

Nat Genet. 2007 Sep;39(9):1068-70. Epub 2007 Jul 29.PMID: 17660820 [PubMed - indexed for MEDLINE]Related articles

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome.

Kavanagh D, Richards A, Noris M, Hauhart R, Liszewski MK, Karpman D, Goodship JA, Fremeaux-Bacchi V, Remuzzi G, Goodship TH, Atkinson JP.

Mol Immunol. 2008 Jan;45(1):95-105. Epub 2007 Jun 26.PMID: 17597211 [PubMed - indexed for MEDLINE]Related articles

Complement factor H and the hemolytic uremic syndrome.

Atkinson JP, Goodship TH.

J Exp Med. 2007 Jun 11;204(6):1245-8. Epub 2007 Jun 4. Review.PMID: 17548524 [PubMed - indexed for MEDLINE]Related articlesFree article

The decay accelerating factor mutation I197V found in hemolytic uraemic syndrome does not impair complement regulation.

Kavanagh D, Burgess R, Spitzer D, Richards A, Diaz-Torres ML, Goodship JA, Hourcade DE, Atkinson JP, Goodship TH.

Mol Immunol. 2007 May;44(12):3162-7. Epub 2007 Mar 21.PMID: 17368771 [PubMed - indexed for MEDLINE]Related articles

CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes.

Caudy AA, Reddy ST, Chatila T, Atkinson JP, Verbsky JW.

J Allergy Clin Immunol. 2007 Feb;119(2):482-7. Epub 2006 Dec 27.PMID: 17196245 [PubMed - indexed for MEDLINE]Related articles

T-cell regulation: with complements from innate immunity.

Kemper C, Atkinson JP.

Nat Rev Immunol. 2007 Jan;7(1):9-18. Epub 2006 Dec 1. Review.PMID: 17170757 [PubMed - indexed for MEDLINE]Related articles

Homozygous C1 inhibitor deficiency: The conclusion of a long search.

Frank MM, Atkinson JP.

J Allergy Clin Immunol. 2006 Dec;118(6):1327-9. No abstract available. PMID: 17157664 [PubMed - indexed for MEDLINE]Related articles

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H.

Chung KM, Liszewski MK, Nybakken G, Davis AE, Townsend RR, Fremont DH, Atkinson JP, Diamond MS.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19111-6. Epub 2006 Nov 28.PMID: 17132743 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome.

Liszewski MK, Leung MK, Schraml B, Goodship TH, Atkinson JP.

Mol Immunol. 2007 Mar;44(7):1559-68. Epub 2006 Oct 5.PMID: 17027083 [PubMed - indexed for MEDLINE]Related articlesFree article

Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.

Spitzer D, Wu X, Ma X, Xu L, Ponder KP, Atkinson JP.

J Immunol. 2006 Oct 15;177(8):4953-6.PMID: 17015675 [PubMed - indexed for MEDLINE]Related articlesFree article

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.

Richards A, Kathryn Liszewski M, Kavanagh D, Fang CJ, Moulton E, Fremeaux-Bacchi V, Remuzzi G, Noris M, Goodship TH, Atkinson JP.

Mol Immunol. 2007 Jan;44(1-3):111-22. Epub 2006 Aug 1. Review.PMID: 16882452 [PubMed - indexed for MEDLINE]Related articles

Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.

Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, Arzouk N, Cleper R, Francois M, Guest G, Pourrat J, Seligman R, Fridman WH, Loirat C, Atkinson JP.

J Am Soc Nephrol. 2006 Jul;17(7):2017-25. Epub 2006 Jun 8.PMID: 16762990 [PubMed - indexed for MEDLINE]Related articlesFree article

Bypassing complement: evolutionary lessons and future implications.

Atkinson JP, Frank MM.

J Clin Invest. 2006 May;116(5):1215-8.PMID: 16670764 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, Bettinaglio P, Mele C, Bresin E, Cassis L, Gamba S, Porrati F, Bucchioni S, Monteferrante G, Fang CJ, Liszewski MK, Kavanagh D, Atkinson JP, Remuzzi G; International Registry of Recurrent and Familial HUS/TTP.

Blood. 2006 Aug 15;108(4):1267-79. Epub 2006 Apr 18.PMID: 16621965 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure and regulatory profile of the monkeypox inhibitor of complement: comparison to homologs in vaccinia and variola and evidence for dimer formation.

Liszewski MK, Leung MK, Hauhart R, Buller RM, Bertram P, Wang X, Rosengard AM, Kotwal GJ, Atkinson JP.

J Immunol. 2006 Mar 15;176(6):3725-34.PMID: 16517741 [PubMed - indexed for MEDLINE]Related articlesFree article

C5a and Fcgamma receptors: a mutual admiration society.

Atkinson JP.

J Clin Invest. 2006 Feb;116(2):304-6.PMID: 16453017 [PubMed - indexed for MEDLINE]Related articlesFree article

Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue.

Atkinson JP, Liszewski MK, Richards A, Kavanagh D, Moulton EA.

Ann N Y Acad Sci. 2005 Nov;1056:144-52. Review.PMID: 16387683 [PubMed - indexed for MEDLINE]Related articles

In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.

Spitzer D, Unsinger J, Mao D, Wu X, Molina H, Atkinson JP.

J Immunol. 2005 Dec 1;175(11):7763-70.PMID: 16301687 [PubMed - indexed for MEDLINE]Related articlesFree article

CD46 is a cellular receptor for all species B adenoviruses except types 3 and 7.

Marttila M, Persson D, Gustafsson D, Liszewski MK, Atkinson JP, Wadell G, Arnberg N.

J Virol. 2005 Nov;79(22):14429-36.PMID: 16254377 [PubMed - indexed for MEDLINE]Related articlesFree article

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.

Barchet W, Price JD, Cella M, Colonna M, MacMillan SK, Cobb JP, Thompson PA, Murphy KM, Atkinson JP, Kemper C.

Blood. 2006 Feb 15;107(4):1497-504. Epub 2005 Oct 20.PMID: 16239430 [PubMed - indexed for MEDLINE]Related articlesFree article

Release of host-derived membrane vesicles following pilus-mediated adhesion of Neisseria gonorrhoeae.

Gill DB, Spitzer D, Koomey M, Heuser JE, Atkinson JP.

Cell Microbiol. 2005 Nov;7(11):1672-83.PMID: 16207253 [PubMed - indexed for MEDLINE]Related articles

Emerging roles and new functions of CD46.

Liszewski MK, Kemper C, Price JD, Atkinson JP.

Springer Semin Immunopathol. 2005 Nov;27(3):345-58. Epub 2005 Nov 11. Review.PMID: 16200405 [PubMed - indexed for MEDLINE]Related articles

Synergy between two active sites of human complement receptor type 1 (CD35) in complement regulation: implications for the structure of the classical pathway C3 convertase and generation of more potent inhibitors.

Krych-Goldberg M, Hauhart RE, Porzukowiak T, Atkinson JP.

J Immunol. 2005 Oct 1;175(7):4528-35.PMID: 16177096 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell stimulation and regulation: with complements from CD46.

Kemper C, Verbsky JW, Price JD, Atkinson JP.

Immunol Res. 2005;32(1-3):31-43. Review.PMID: 16106057 [PubMed - indexed for MEDLINE]Related articles

Virulence differences between monkeypox virus isolates from West Africa and the Congo basin.

Chen N, Li G, Liszewski MK, Atkinson JP, Jahrling PB, Feng Z, Schriewer J, Buck C, Wang C, Lefkowitz EJ, Esposito JJ, Harms T, Damon IK, Roper RL, Upton C, Buller RM.

Virology. 2005 Sep 15;340(1):46-63.PMID: 16023693 [PubMed - indexed for MEDLINE]Related articles

Induction of a regulatory phenotype in human CD4+ T cells by streptococcal M protein.

Price JD, Schaumburg J, Sandin C, Atkinson JP, Lindahl G, Kemper C.

J Immunol. 2005 Jul 15;175(2):677-84.PMID: 16002662 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel complement inhibitors.

Liszewski MK, Atkinson JP.

Expert Opin Investig Drugs. 1998 Mar;7(3):323-31.PMID: 15991975 [PubMed]Related articles

Localization of regions in CD46 that interact with adenovirus.

Gaggar A, Shayakhmetov DM, Liszewski MK, Atkinson JP, Lieber A.

J Virol. 2005 Jun;79(12):7503-13.PMID: 15919905 [PubMed - indexed for MEDLINE]Related articlesFree article