PubMed

HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: A genome-wide association study in Koreans with replication in North Americans.

Zhou X, Lee JE, Arnett FC, Xiong M, Park MY, Yoo YK, Shin ES, Reveille JD, Mayes MD, Kim JH, Song R, Choi JY, Park JA, Lee YJ, Lee EY, Song YW, Lee EB.

Arthritis Rheum. 2009 Nov 30;60(12):3807-3814. [Epub ahead of print]PMID: 19950302 [PubMed - as supplied by publisher]

The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.

Broen J, Gourh P, Rueda B, Coenen M, Mayes M, Martin J, Arnett FC, Radstake TR; European Consortium on Systemic Sclerosis Genetics.

Arthritis Rheum. 2009 Nov 30;60(12):3815-3820. [Epub ahead of print]PMID: 19950259 [PubMed - as supplied by publisher]

Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: Evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines.

Gourh P, Agarwal SK, Divecha D, Assassi S, Paz G, Arora-Singh RK, Reveille JD, Shete S, Mayes MD, Arnett FC, Tan FK.

Arthritis Rheum. 2009 Nov 30;60(12):3794-3806. [Epub ahead of print]PMID: 19950257 [PubMed - as supplied by publisher]

Novel Sequence Feature Variant Type Analysis of the HLA Genetic Association in Systemic Sclerosis.

Karp DR, Marthandan N, Marsh SG, Ahn C, Arnett FC, Deluca DS, Diehl AD, Dunivin R, Eilbeck K, Feolo M, Guidry PA, Helmberg W, Lewis S, Mayes MD, Mungall C, Natale DA, Peters B, Petersdorf E, Reveille JD, Smith B, Thomson G, Waller MJ, Scheuermann RH.

Hum Mol Genet. 2009 Nov 18. [Epub ahead of print]PMID: 19933168 [PubMed - as supplied by publisher]

Association of Interleukin 23 Receptor Polymorphisms with Anti-Topoisomerase-I Positivity and Pulmonary Hypertension in Systemic Sclerosis.

Agarwal SK, Gourh P, Shete S, Paz G, Divecha D, Reveille JD, Assassi S, Tan FK, Mayes MD, Arnett FC.

J Rheumatol. 2009 Nov 16. [Epub ahead of print]PMID: 19918037 [PubMed - as supplied by publisher]Related articles

BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians.

Rueda B, Gourh P, Broen J, Agarwal SK, Simeón CP, Ortego-Centeno N, Vonk MC, Coenen M, Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assasi S, Garcia-Hernandez FJ, Carreira P, Camps M, Fernandez-Nebro A, Garcia de la Peña P, Nearney T, Hilda D, Gónzalez-Gay MA, Airo P, Beretta L, Scorza R, Radstake TR, Mayes M, Arnett FC, Martin J.

Ann Rheum Dis. 2009 Oct 8. [Epub ahead of print]PMID: 19815934 [PubMed - as supplied by publisher]Related articles

Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.

Gourh P, Arnett FC, Assassi S, Tan FK, Huang M, Diekman L, Mayes MD, Reveille JD, Agarwal SK.

Arthritis Res Ther. 2009;11(5):R147. Epub 2009 Oct 2.PMID: 19799786 [PubMed - as supplied by publisher]Related articles

Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations.

Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H, Assassi S, Paz G, Shete S, McNearney T, Draeger H, Reveille JD, Radstake TR, Simeon CP, Rodriguez L, Vicente E, Gonzalez-Gay MA, Mayes MD, Tan FK, Martin J, Arnett FC.

J Autoimmun. 2009 Sep 29. [Epub ahead of print]PMID: 19796918 [PubMed - as supplied by publisher]Related articles

Clinical and genetic factors predictive of mortality in early systemic sclerosis.

Assassi S, Del Junco D, Sutter K, McNearney TA, Reveille JD, Karnavas A, Gourh P, Estrada-Y-Martin RM, Fischbach M, Arnett FC, Mayes MD.

Arthritis Rheum. 2009 Oct 15;61(10):1403-11.PMID: 19790132 [PubMed - indexed for MEDLINE]Related articles

Association of TNFSF4 (OX40L) polymorphisms with susceptibility to Systemic Sclerosis.

Gourh P, Arnett FC, Tan FK, Assassi S, Divecha D, Paz G, McNearney T, Draeger H, Reveille JD, Mayes MD, Agarwal SK.

Ann Rheum Dis. 2009 Sep 23. [Epub ahead of print]PMID: 19778912 [PubMed - as supplied by publisher]Related articlesFree article

Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abnormalities in a large population of systemic sclerosis patients.

Assassi S, Fritzler MJ, Arnett FC, Norman GL, Shah KR, Gourh P, Manek N, Perry M, Ganesh D, Rahbar MH, Mayes MD.

J Rheumatol. 2009 Oct;36(10):2250-6. Epub 2009 Sep 1.PMID: 19723904 [PubMed - in process]Related articles

Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women.

Love LA, Weinberg CR, McConnaughey DR, Oddis CV, Medsger TA Jr, Reveille JD, Arnett FC, Targoff IN, Miller FW.

Arthritis Rheum. 2009 Aug;60(8):2499-504.PMID: 19644877 [PubMed - indexed for MEDLINE]Related articles

Major Histocompatibility Complex (MHC) class II alleles, haplotypes, and epitopes which confer susceptibility or protection in the fibrosing autoimmune disease systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls.

Arnett FC, Gourh P, Shete S, Ahn CW, Honey R, Agarwal SK, Tan FK, McNearney T, Fischbach M, Fritzler MJ, Mayes MD, Reveille JD.

Ann Rheum Dis. 2009 Jul 12. [Epub ahead of print]PMID: 19596691 [PubMed - as supplied by publisher]Related articlesFree article

A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus.

Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S; Italian Collaborative Group, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel B, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N.

Hum Mol Genet. 2009 Feb 1;18(3):569-79. Epub 2008 Nov 3.PMID: 18981062 [PubMed - indexed for MEDLINE]Related articles

Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic aneurysms.

He R, Guo DC, Sun W, Papke CL, Duraisamy S, Estrera AL, Safi HJ, Ahn C, Buja LM, Arnett FC, Zhang J, Geng YJ, Milewicz DM.

J Thorac Cardiovasc Surg. 2008 Oct;136(4):922-9, 929.e1. Epub 2008 Jun 12.PMID: 18954631 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis.

Kim D, Peck A, Santer D, Patole P, Schwartz SM, Molitor JA, Arnett FC, Elkon KB.

Arthritis Rheum. 2008 Jul;58(7):2163-73.PMID: 18576347 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics and genomic studies in scleroderma (systemic sclerosis).

Agarwal SK, Tan FK, Arnett FC.

Rheum Dis Clin North Am. 2008 Feb;34(1):17-40; v. Review.PMID: 18329530 [PubMed - indexed for MEDLINE]Related articles

Differential dynamic properties of scleroderma fibroblasts in response to perturbation of environmental stimuli.

Xiong M, Arnett FC, Guo X, Xiong H, Zhou X.

PLoS One. 2008 Feb 27;3(2):e1693.PMID: 18301770 [PubMed - indexed for MEDLINE]Related articlesFree article

CTGF polymorphism associated with systemic sclerosis.

Gourh P, Mayes MD, Arnett FC.

N Engl J Med. 2008 Jan 17;358(3):308-9; author reply 309. No abstract available. PMID: 18203332 [PubMed - indexed for MEDLINE]Related articles

Clinical, immunologic, and genetic features of familial systemic sclerosis.

Assassi S, Arnett FC, Reveille JD, Gourh P, Mayes MD.

Arthritis Rheum. 2007 Jun;56(6):2031-7.PMID: 17530643 [PubMed - indexed for MEDLINE]Related articlesFree article

An allograft inflammatory factor 1 (AIF1) single nucleotide polymorphism (SNP) is associated with anticentromere antibody positive systemic sclerosis.

Alkassab F, Gourh P, Tan FK, McNearney T, Fischbach M, Ahn C, Arnett FC, Mayes MD.

Rheumatology (Oxford). 2007 Aug;46(8):1248-51. Epub 2007 May 23.PMID: 17522098 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus.

Wu H, Boackle SA, Hanvivadhanakul P, Ulgiati D, Grossman JM, Lee Y, Shen N, Abraham LJ, Mercer TR, Park E, Hebert LA, Rovin BH, Birmingham DJ, Chang DM, Chen CJ, McCurdy D, Badsha HM, Thong BY, Chng HH, Arnett FC, Wallace DJ, Yu CY, Hahn BH, Cantor RM, Tsao BP.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3961-6. Epub 2007 Feb 22.PMID: 17360460 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors.

McNearney TA, Reveille JD, Fischbach M, Friedman AW, Lisse JR, Goel N, Tan FK, Zhou X, Ahn C, Feghali-Bostwick CA, Fritzler M, Arnett FC, Mayes MD.

Arthritis Rheum. 2007 Mar 15;57(2):318-26.PMID: 17330281 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the PTPN22 R620W polymorphism with anti-topoisomerase I- and anticentromere antibody-positive systemic sclerosis.

Gourh P, Tan FK, Assassi S, Ahn CW, McNearney TA, Fischbach M, Arnett FC, Mayes MD.

Arthritis Rheum. 2006 Dec;54(12):3945-53.PMID: 17133608 [PubMed - indexed for MEDLINE]Related articlesFree article

SPARC, an upstream regulator of connective tissue growth factor in response to transforming growth factor beta stimulation.

Zhou XD, Xiong MM, Tan FK, Guo XJ, Arnett FC.

Arthritis Rheum. 2006 Dec;54(12):3885-9.PMID: 17133596 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies.

O'Hanlon TP, Rider LG, Mamyrova G, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Chanock SJ, Foster CB, Bunch T, Reed AM, Love LA, Miller FW.

Arthritis Rheum. 2006 Nov;54(11):3670-81.PMID: 17075818 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma.

Wu SP, Leng L, Feng Z, Liu N, Zhao H, McDonald C, Lee A, Arnett FC, Gregersen PK, Mayes MD, Bucala R.

Arthritis Rheum. 2006 Nov;54(11):3661-9.PMID: 17075815 [PubMed - indexed for MEDLINE]Related articlesFree article

Is scleroderma an autoantibody mediated disease?

Arnett FC.

Curr Opin Rheumatol. 2006 Nov;18(6):579-81. Review.PMID: 17053501 [PubMed - indexed for MEDLINE]Related articles

A mariner with crippling arthritis and bleeding eyes.

Arnett FC, Merrill C, Albardaner F, Mackowiak PA.

Am J Med Sci. 2006 Sep;332(3):123-30.PMID: 16969141 [PubMed - indexed for MEDLINE]Related articles

Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma.

Zhou X, Tan FK, Guo X, Arnett FC.

Arthritis Rheum. 2006 Aug;54(8):2626-31.PMID: 16871529 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of apoptosis and fibrillin 1 expression in human dermal endothelial cells by scleroderma sera containing anti-endothelial cell antibodies.

Ahmed SS, Tan FK, Arnett FC, Jin L, Geng YJ.

Arthritis Rheum. 2006 Jul;54(7):2250-62.PMID: 16802364 [PubMed - indexed for MEDLINE]Related articlesFree article

Alu insertion polymorphisms in Native Americans and related Asian populations.

Battilana J, Fagundes NJ, Heller AH, Goldani A, Freitas LB, Tarazona-Santos E, Munkhbat B, Munkhtuvshin N, Krylov M, Benevolenskaia L, Arnett FC, Batzer MA, Deininger PL, Salzano FM, Bonatto SL.

Ann Hum Biol. 2006 Mar-Apr;33(2):142-60.PMID: 16684689 [PubMed - indexed for MEDLINE]Related articles

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

O'Hanlon TP, Carrick DM, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Blackshear PJ, Plotz PH, Love LA, Miller FW.

Medicine (Baltimore). 2006 Mar;85(2):111-27.PMID: 16609350 [PubMed - indexed for MEDLINE]Related articles

Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients.

Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, Marcum C, Jin L, Arnett FC Jr.

Rheumatology (Oxford). 2006 Jun;45(6):694-702. Epub 2006 Jan 17.PMID: 16418202 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians.

O'Hanlon TP, Carrick DM, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Dreyfuss J, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Plotz PH, Love LA, Miller FW.

Medicine (Baltimore). 2005 Nov;84(6):338-49.PMID: 16267409 [PubMed - indexed for MEDLINE]Related articles

Monozygotic twins clinically discordant for scleroderma show concordance for fibroblast gene expression profiles.

Zhou X, Tan FK, Xiong M, Arnett FC, Feghali-Bostwick CA.

Arthritis Rheum. 2005 Oct;52(10):3305-14.PMID: 16200604 [PubMed - indexed for MEDLINE]Related articlesFree article

A systems biology approach to genetic studies of complex diseases.

Xiong M, Feghali-Bostwick CA, Arnett FC, Zhou X.

FEBS Lett. 2005 Oct 10;579(24):5325-32.PMID: 16182293 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies to fibrillin-1 activate normal human fibroblasts in culture through the TGF-beta pathway to recapitulate the "scleroderma phenotype".

Zhou X, Tan FK, Milewicz DM, Guo X, Bona CA, Arnett FC.

J Immunol. 2005 Oct 1;175(7):4555-60.PMID: 16177099 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in systemic sclerosis.

Assassi S, Mayes MD, McNearney T, Fischbach M, Reveille JD, Arnett FC, Tan FK.

Am J Med. 2005 Aug;118(8):907-11. No abstract available. PMID: 16084185 [PubMed - indexed for MEDLINE]Related articles

Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups.

Sarkar K, Weinberg CR, Oddis CV, Medsger TA Jr, Plotz PH, Reveille JD, Arnett FC, Targoff IN, Genth E, Love LA, Miller FW.

Arthritis Rheum. 2005 Aug;52(8):2433-8.PMID: 16052581 [PubMed - indexed for MEDLINE]Related articlesFree article

Spondyloarthritis: update on pathogenesis and management.

Reveille JD, Arnett FC.

Am J Med. 2005 Jun;118(6):592-603. Review.PMID: 15922688 [PubMed - indexed for MEDLINE]Related articles

Intra- and intercontinental molecular variability of an Alu insertion in the 3' untranslated region of the LDLR gene.

Heller AH, Salzano FM, Barrantes R, Krylov M, Benevolenskaya L, Arnett FC, Munkhbat B, Munkhtuvshin N, Tsuji K, Hutz MH, Carnese FR, Goicoechea AS, Freitas LB, Bonatto SL.

Hum Biol. 2004 Aug;76(4):591-604.PMID: 15754974 [PubMed - indexed for MEDLINE]Related articles

Classification analysis of the transcriptosome of nonlesional cultured dermal fibroblasts from systemic sclerosis patients with early disease.

Tan FK, Hildebrand BA, Lester MS, Stivers DN, Pounds S, Zhou X, Wallis DD, Milewicz DM, Reveille JD, Mayes MD, Jin L, Arnett FC Jr.

Arthritis Rheum. 2005 Mar;52(3):865-76.PMID: 15751056 [PubMed - indexed for MEDLINE]Related articlesFree article

Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor beta1 in cultured normal human fibroblasts.

Zhou X, Tan FK, Guo X, Wallis D, Milewicz DM, Xue S, Arnett FC.

Arthritis Rheum. 2005 Jan;52(1):257-61.PMID: 15641096 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotypic analysis of the TGF beta-509 allele in patients with systemic lupus erythematosus and Sjogren's syndrome.

Caserta TM, Knisley AA, Tan FK, Arnett FC, Brown TL.

Ann Genet. 2004 Oct-Dec;47(4):359-63.PMID: 15581833 [PubMed - indexed for MEDLINE]Related articles

Genetic signatures of pre-expansion bottleneck in the Choctaw population of Oklahoma.

Wang N, Zhou X, Tan FK, Foster MW, Arnett FC, Chakraborty R.

Am J Phys Anthropol. 2004 Aug;124(4):373-9.PMID: 15252865 [PubMed - indexed for MEDLINE]Related articles

cDNA microarrays reveal distinct gene expression clusters in idiopathic inflammatory myopathies.

Zhou X, Dimachkie MM, Xiong M, Tan FK, Arnett FC.

Med Sci Monit. 2004 Jul;10(7):BR191-7. Epub 2004 Jun 29.PMID: 15232492 [PubMed - indexed for MEDLINE]Related articles

Fibrillin 1 abnormalities in dermal fibroblast cultures from first-degree relatives of patients with systemic sclerosis (scleroderma).

Wallis DD, Tan FK, Kessler R, Kimball MD, Cretoiu JS, Arnett FC, Milewicz DM.

Arthritis Rheum. 2004 Jan;50(1):329-32. No abstract available. PMID: 14730633 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome.

Manavalan SJ, Valiando JR, Reeves WH, Arnett FC, Necker A, Simantov R, Lyons R, Satoh M, Posnett DN.

Arthritis Rheum. 2004 Jan;50(1):187-98.PMID: 14730616 [PubMed - indexed for MEDLINE]Related articlesFree article

Examination of the possible role of biologically relevant genes around FBN1 in systemic sclerosis in the Choctaw population.

Tan FK, Tercero GM, Arnett FC, Wang N, Chakraborty R.

Arthritis Rheum. 2003 Nov;48(11):3295-6. No abstract available. PMID: 14613297 [PubMed - indexed for MEDLINE]Related articlesFree article