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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1985 1
1986 1
1992 2
1993 2
1995 1
1996 6
1997 4
1998 2
1999 5
2000 3
2001 5
2002 9
2003 5
2004 6
2005 6
2006 7
2007 12
2008 14
2009 9
2010 12
2011 12
2012 24
2013 26
2014 15
2015 18
2016 33
2017 17
2018 17
2019 31
2020 36
2021 31
2022 28
2023 23
2024 14

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364 results

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Page 1
Opioid Management of Dyspnea at End of Life: A Systematic Review.
Obarzanek L, Wu W, Tutag-Lehr V. Obarzanek L, et al. J Palliat Med. 2023 May;26(5):711-726. doi: 10.1089/jpm.2022.0311. Epub 2022 Nov 28. J Palliat Med. 2023. PMID: 36453988 Review.
Objective: The objective of this systematic review is to consolidate the existing evidence on opioid use, including administration, dosing, and efficacy, for the relief of dyspnea at end of life. The overarching goal is to optimize clinical management of dyspnea
Objective: The objective of this systematic review is to consolidate the existing evidence on opioid use, including administration, dosing, …
Strategies to relieve dyspnoea in patients with advanced chronic respiratory diseases. A narrative review.
Ambrosino N, Fracchia C. Ambrosino N, et al. Pulmonology. 2019 Sep-Oct;25(5):289-298. doi: 10.1016/j.pulmoe.2019.04.002. Epub 2019 May 22. Pulmonology. 2019. PMID: 31129045 Free article. Review.
This review summarizes the latest evidence on interventions to relieve dyspnoea in these patients. METHODS: We searched randomised controlled trials, observational studies, systematic reviews, and meta-analyses published between 1990 and 2019 in English in PubMed da …
This review summarizes the latest evidence on interventions to relieve dyspnoea in these patients. METHODS: We searched randomised
Management of Dyspnea in Advanced Cancer: ASCO Guideline.
Hui D, Bohlke K, Bao T, Campbell TC, Coyne PJ, Currow DC, Gupta A, Leiser AL, Mori M, Nava S, Reinke LF, Roeland EJ, Seigel C, Walsh D, Campbell ML. Hui D, et al. J Clin Oncol. 2021 Apr 20;39(12):1389-1411. doi: 10.1200/JCO.20.03465. Epub 2021 Feb 22. J Clin Oncol. 2021. PMID: 33617290
PURPOSE: To provide guidance on the clinical management of dyspnea in adult patients with advanced cancer. ...A meta-analysis of specialty breathlessness services reported improvements in distress because of dyspnea. RECOMMENDATIONS: A hierarchical approach t …
PURPOSE: To provide guidance on the clinical management of dyspnea in adult patients with advanced cancer. ...A meta-analysis …
Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial.
Ekström M, Ferreira D, Chang S, Louw S, Johnson MJ, Eckert DJ, Fazekas B, Clark KJ, Agar MR, Currow DC; Australian National Palliative Care Clinical Studies Collaborative. Ekström M, et al. JAMA. 2022 Nov 22;328(20):2022-2032. doi: 10.1001/jama.2022.20206. JAMA. 2022. PMID: 36413230 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: Multicenter, double-blind, placebo-controlled randomized clinical trial including people with COPD and chronic breathlessness (defined as a modified Medical Research Council score of 3 to 4) conducted at 20 centers in Austra …
DESIGN, SETTING, AND PARTICIPANTS: Multicenter, double-blind, placebo-controlled randomized clinical trial including pe …
Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.
COVID STEROID 2 Trial Group; Munch MW, Myatra SN, Vijayaraghavan BKT, Saseedharan S, Benfield T, Wahlin RR, Rasmussen BS, Andreasen AS, Poulsen LM, Cioccari L, Khan MS, Kapadia F, Divatia JV, Brøchner AC, Bestle MH, Helleberg M, Michelsen J, Padmanaban A, Bose N, Møller A, Borawake K, Kristiansen KT, Shukla U, Chew MS, Dixit S, Ulrik CS, Amin PR, Chawla R, Wamberg CA, Shah MS, Darfelt IS, Jørgensen VL, Smitt M, Granholm A, Kjær MN, Møller MH, Meyhoff TS, Vesterlund GK, Hammond NE, Micallef S, Bassi A, John O, Jha A, Cronhjort M, Jakob SM, Gluud C, Lange T, Kadam V, Marcussen KV, Hollenberg J, Hedman A, Nielsen H, Schjørring OL, Jensen MQ, Leistner JW, Jonassen TB, Kristensen CM, Clapp EC, Hjortsø CJS, Jensen TS, Halstad LS, Bak ERB, Zaabalawi R, Metcalf-Clausen M, Abdi S, Hatley EV, Aksnes TS, Gleipner-Andersen E, Alarcón AF, Yamin G, Heymowski A, Berggren A, La Cour K, Weihe S, Pind AH, Engstrøm J, Jha V, Venkatesh B, Perner A. COVID STEROID 2 Trial Group, et al. JAMA. 2021 Nov 9;326(18):1807-1817. doi: 10.1001/jama.2021.18295. JAMA. 2021. PMID: 34673895 Free PMC article. Clinical Trial.
OBJECTIVE: To assess the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia. DESIGN, SETTING, AND PARTICIPANTS: A multicenter, randomized clinical trial was conducted between August 2020 and May 2021 at 26 hospitals i …
OBJECTIVE: To assess the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia. DESIGN, SETTING, AND …
An integrated palliative and respiratory care service for patients with advanced disease and refractory breathlessness: a randomised controlled trial.
Higginson IJ, Bausewein C, Reilly CC, Gao W, Gysels M, Dzingina M, McCrone P, Booth S, Jolley CJ, Moxham J. Higginson IJ, et al. Lancet Respir Med. 2014 Dec;2(12):979-87. doi: 10.1016/S2213-2600(14)70226-7. Epub 2014 Oct 29. Lancet Respir Med. 2014. PMID: 25465642 Free article. Clinical Trial.
METHODS: In this single-blind randomised trial, we enrolled consecutive adults with refractory breathlessness and advanced disease from three large teaching hospitals and via general practitioners in South London. ...Randomisation was computer generated centr …
METHODS: In this single-blind randomised trial, we enrolled consecutive adults with refractory breathlessness and advanced dis …
Intrapleural therapy.
Huggins JT, Doelken P, Sahn SA. Huggins JT, et al. Respirology. 2011 Aug;16(6):891-9. doi: 10.1111/j.1440-1843.2011.02011.x. Respirology. 2011. PMID: 21672085 Review.
In the largest randomized trial, the use of streptokinase had no reduction in mortality, decortication rates or hospital days compared with placebo in the treatment of empyema. ...For patients with malignant-related lung entrapment, pleurodesis often fails due to th …
In the largest randomized trial, the use of streptokinase had no reduction in mortality, decortication rates or hospital days …
Telephone interventions for symptom management in adults with cancer.
Ream E, Hughes AE, Cox A, Skarparis K, Richardson A, Pedersen VH, Wiseman T, Forbes A, Bryant A. Ream E, et al. Cochrane Database Syst Rev. 2020 Jun 2;6(6):CD007568. doi: 10.1002/14651858.CD007568.pub2. Cochrane Database Syst Rev. 2020. PMID: 32483832 Free PMC article.
Finally, we handsearched the following journals: Cancer, Journal of Clinical Oncology, Psycho-oncology, Cancer Practice, Cancer Nursing, Oncology Nursing Forum, Journal of Pain and Symptom Management, and Palliative Medicine. We restricted our search to publications …
Finally, we handsearched the following journals: Cancer, Journal of Clinical Oncology, Psycho-oncology, Cancer Practice, Cancer Nursi …
Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status: A Randomized Clinical Trial.
Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Hameleers N, Wouters EFM, Janssen DJA. Verberkt CA, et al. JAMA Intern Med. 2020 Oct 1;180(10):1306-1314. doi: 10.1001/jamainternmed.2020.3134. JAMA Intern Med. 2020. PMID: 32804188 Free PMC article. Clinical Trial.
No morphine-related hospital admissions or deaths occurred. CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, regular, low-dose, oral sustained-release morphine for 4 weeks improved disease-specific health status in patients with COPD without affe …
No morphine-related hospital admissions or deaths occurred. CONCLUSIONS AND RELEVANCE: In this randomized clinical trial
Dyspnoea-12 and Multidimensional Dyspnea Profile: Systematic Review of Use and Properties.
Williams MT, Lewthwaite H, Paquet C, Johnston K, Olsson M, Belo LF, Pitta F, Morelot-Panzini C, Ekström M. Williams MT, et al. J Pain Symptom Manage. 2022 Jan;63(1):e75-e87. doi: 10.1016/j.jpainsymman.2021.06.023. Epub 2021 Jul 15. J Pain Symptom Manage. 2022. PMID: 34273524 Free article. Review.
CONTEXT: The Dyspnoea-12 (D-12) and Multidimensional Dyspnea Profile (MDP) were specifically developed for assessment of multiple sensations of breathlessness. ...Study and participant characteristics, instrument use, reported scores and minimal clinical impo …
CONTEXT: The Dyspnoea-12 (D-12) and Multidimensional Dyspnea Profile (MDP) were specifically developed for assessment of multi …
364 results